Location and Characterization of Myocardial Infarctions Using a Multielectrode, Intracavitary Probe

It has been suggested that catheter ablation would be more effective if it could completely ablate the thin rim of spared endocardium overlying a myocardial infarction (MI). In order to accomplish such an MI-related ablation, the MI must be located and its boundaries delineated. This model study ezplores the we of a multielectrode, intracavitary probe to locate and characterize MI’S. Maximum likelihood estimation (MLE) was performed on the average of many cardiac cycles from a spherical shells model. In repeated simulations, it was always possible to reduce the rms estimation error for both size and location to below 1 mm of endocardial distance, even in the presence of noise and probe movement.

Duke Scholars

Author Robert A. Malkin Biomedical Engineering