Clathrin adaptor EPSIN1 (EPS1) modulates plasma membrane abundance of PLEIOTROPIC DRUG RESISTANCE PDR9 for effective hormone homeostasis.
Publication
, Journal Article
Nguyen, NT; LaMontagne-Mueller, ED; Kauffman, GF; Vedra, M; Peck, SC; Strader, LC; Heese, A
Published in: The New phytologist
April 2026
The cellular machinery that directs the indole-3-butyric acid (IBA) effluxer PLEIOTROPIC DRUG RESISTANCE 9 (PDR9) to the outer plasma membrane (PM) domain of the root epidermis remains poorly understood. This study combines biochemical fractionation, live-cell imaging, and physiological assays to identify the trans-Golgi Network-localized clathrin adaptor EPSIN1 (EPS1) as a novel modulator of PDR9 abundance at the root PM for IBA-dependent physiological processes. These findings expand EPS1's roles from plant immunity to hormone homeostasis, thereby advancing the limited understanding of biological functions for plant EPSINs.
Duke Scholars
Published In
The New phytologist
DOI
EISSN
1469-8137
ISSN
1469-8137
Publication Date
April 2026
Related Subject Headings
- Plant Biology & Botany
- 4102 Ecological applications
- 4101 Climate change impacts and adaptation
- 3108 Plant biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Nguyen, N. T., LaMontagne-Mueller, E. D., Kauffman, G. F., Vedra, M., Peck, S. C., Strader, L. C., & Heese, A. (2026). Clathrin adaptor EPSIN1 (EPS1) modulates plasma membrane abundance of PLEIOTROPIC DRUG RESISTANCE PDR9 for effective hormone homeostasis. The New Phytologist. https://doi.org/10.1111/nph.71208
Nguyen, Nga T., Erica D. LaMontagne-Mueller, Gabriela F. Kauffman, Margaret Vedra, Scott C. Peck, Lucia C. Strader, and Antje Heese. “Clathrin adaptor EPSIN1 (EPS1) modulates plasma membrane abundance of PLEIOTROPIC DRUG RESISTANCE PDR9 for effective hormone homeostasis.” The New Phytologist, April 2026. https://doi.org/10.1111/nph.71208.
Nguyen NT, LaMontagne-Mueller ED, Kauffman GF, Vedra M, Peck SC, Strader LC, et al. Clathrin adaptor EPSIN1 (EPS1) modulates plasma membrane abundance of PLEIOTROPIC DRUG RESISTANCE PDR9 for effective hormone homeostasis. The New phytologist. 2026 Apr;
Nguyen, Nga T., et al. “Clathrin adaptor EPSIN1 (EPS1) modulates plasma membrane abundance of PLEIOTROPIC DRUG RESISTANCE PDR9 for effective hormone homeostasis.” The New Phytologist, Apr. 2026. Epmc, doi:10.1111/nph.71208.
Nguyen NT, LaMontagne-Mueller ED, Kauffman GF, Vedra M, Peck SC, Strader LC, Heese A. Clathrin adaptor EPSIN1 (EPS1) modulates plasma membrane abundance of PLEIOTROPIC DRUG RESISTANCE PDR9 for effective hormone homeostasis. The New phytologist. 2026 Apr;
Published In
The New phytologist
DOI
EISSN
1469-8137
ISSN
1469-8137
Publication Date
April 2026
Related Subject Headings
- Plant Biology & Botany
- 4102 Ecological applications
- 4101 Climate change impacts and adaptation
- 3108 Plant biology