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Localization of the mouse gene for secreted phosphoprotein 1 (Spp-1) (2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphoprotein, tumor-secreted phosphoprotein) to chromosome 5, closely linked to Ric (Rickettsia resistance).
Publication
, Journal Article
Fet, V; Dickinson, ME; Hogan, BL
Published in: Genomics
August 1989
We have used a cDNA probe for mouse secreted phosphoprotein 1 (Spp-1, also known as 2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphotein, tumor-secreted protein) to find a restriction fragment length polymorphism in the gene from C57BL/6J and DBA/2J mice. The strain distribution pattern in 25 BXD recombinant inbred lines is identical with that previously determined for the dominant, autosomal gene, Ricr (Rickettsia resistance). This places Spp-1 on mouse chromosome 5 with a 95% confidence limit of being within 4.32 cM of Ric. Evidence supporting the possibility of allelism between Spp-1 and Ric is briefly discussed.
Duke Scholars
Published In
Genomics
DOI
ISSN
0888-7543
Publication Date
August 1989
Volume
5
Issue
2
Start / End Page
375 / 377
Location
United States
Related Subject Headings
- Sialoglycoproteins
- Rickettsia Infections
- Polymorphism, Restriction Fragment Length
- Phosphoproteins
- Osteopontin
- Mice, Inbred DBA
- Mice, Inbred C57BL
- Mice
- Genetics & Heredity
- DNA Probes
Citation
APA
Chicago
ICMJE
MLA
NLM
Fet, V., Dickinson, M. E., & Hogan, B. L. (1989). Localization of the mouse gene for secreted phosphoprotein 1 (Spp-1) (2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphoprotein, tumor-secreted phosphoprotein) to chromosome 5, closely linked to Ric (Rickettsia resistance). Genomics, 5(2), 375–377. https://doi.org/10.1016/0888-7543(89)90074-8
Fet, V., M. E. Dickinson, and B. L. Hogan. “Localization of the mouse gene for secreted phosphoprotein 1 (Spp-1) (2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphoprotein, tumor-secreted phosphoprotein) to chromosome 5, closely linked to Ric (Rickettsia resistance).” Genomics 5, no. 2 (August 1989): 375–77. https://doi.org/10.1016/0888-7543(89)90074-8.
Fet V, Dickinson ME, Hogan BL. Localization of the mouse gene for secreted phosphoprotein 1 (Spp-1) (2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphoprotein, tumor-secreted phosphoprotein) to chromosome 5, closely linked to Ric (Rickettsia resistance). Genomics. 1989 Aug;5(2):375–7.
Fet, V., et al. “Localization of the mouse gene for secreted phosphoprotein 1 (Spp-1) (2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphoprotein, tumor-secreted phosphoprotein) to chromosome 5, closely linked to Ric (Rickettsia resistance).” Genomics, vol. 5, no. 2, Aug. 1989, pp. 375–77. Pubmed, doi:10.1016/0888-7543(89)90074-8.
Fet V, Dickinson ME, Hogan BL. Localization of the mouse gene for secreted phosphoprotein 1 (Spp-1) (2ar, osteopontin, bone sialoprotein 1, 44-kDa bone phosphoprotein, tumor-secreted phosphoprotein) to chromosome 5, closely linked to Ric (Rickettsia resistance). Genomics. 1989 Aug;5(2):375–377.
![Journal cover image](https://secure.syndetics.com/index.aspx?isbn=/lc.gif&issn=0888-7543&client=dukeuniv)
Published In
Genomics
DOI
ISSN
0888-7543
Publication Date
August 1989
Volume
5
Issue
2
Start / End Page
375 / 377
Location
United States
Related Subject Headings
- Sialoglycoproteins
- Rickettsia Infections
- Polymorphism, Restriction Fragment Length
- Phosphoproteins
- Osteopontin
- Mice, Inbred DBA
- Mice, Inbred C57BL
- Mice
- Genetics & Heredity
- DNA Probes