Skip to main content
Journal cover image

The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats.

Publication ,  Journal Article
Cao, H; Glazebrook, J; Clarke, JD; Volko, S; Dong, X
Published in: Cell
January 1997

The Arabidopsis NPR1 gene controls the onset of systemic acquired resistance (SAR), a plant immunity, to a broad spectrum of pathogens that is normally established after a primary exposure to avirulent pathogens. Mutants with defects in NPR1 fail to respond to various SAR-inducing treatments, displaying little expression of pathogenesis-related (PR) genes and exhibiting increased susceptibility to infections. NPR1 was cloned using a map-based approach and was found to encode a novel protein containing ankyrin repeats. The lesion in one npr1 mutant allele disrupted the ankyrin consensus sequence, suggesting that these repeats are important for NPR1 function. Furthermore, transformation of the cloned wild-type NPR1 gene into npr1 mutants not only complemented the mutations, restoring the responsiveness to SAR induction with respect to PR-gene expression and resistance to infections, but also rendered the transgenic plants more resistant to infection by P. syringae in the absence of SAR induction.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Cell

DOI

EISSN

1097-4172

ISSN

0092-8674

Publication Date

January 1997

Volume

88

Issue

1

Start / End Page

57 / 63

Related Subject Headings

  • Sequence Homology, Amino Acid
  • Sequence Analysis, DNA
  • RNA, Plant
  • RNA, Messenger
  • Plant Proteins
  • Plant Diseases
  • Molecular Sequence Data
  • Genetic Complementation Test
  • Genes, Plant
  • Gene Expression Regulation, Plant
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Cao, H., Glazebrook, J., Clarke, J. D., Volko, S., & Dong, X. (1997). The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats. Cell, 88(1), 57–63. https://doi.org/10.1016/s0092-8674(00)81858-9
Cao, H., J. Glazebrook, J. D. Clarke, S. Volko, and X. Dong. “The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats.Cell 88, no. 1 (January 1997): 57–63. https://doi.org/10.1016/s0092-8674(00)81858-9.
Cao, H., et al. “The Arabidopsis NPR1 gene that controls systemic acquired resistance encodes a novel protein containing ankyrin repeats.Cell, vol. 88, no. 1, Jan. 1997, pp. 57–63. Epmc, doi:10.1016/s0092-8674(00)81858-9.
Journal cover image

Published In

Cell

DOI

EISSN

1097-4172

ISSN

0092-8674

Publication Date

January 1997

Volume

88

Issue

1

Start / End Page

57 / 63

Related Subject Headings

  • Sequence Homology, Amino Acid
  • Sequence Analysis, DNA
  • RNA, Plant
  • RNA, Messenger
  • Plant Proteins
  • Plant Diseases
  • Molecular Sequence Data
  • Genetic Complementation Test
  • Genes, Plant
  • Gene Expression Regulation, Plant