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Electrophoretic evaluation of sera from dogs with cancer.

Publication ,  Journal Article
Phillips, RK; Dewhirst, MW; Gillette, EL; Clow, DJ
Published in: Am J Vet Res
September 1978

A quantitative electrophoretic method was developed for evaluating sera from dogs with naturally occurring malignant tumors. Electrophoretic migration ratios (EMR) were devised to standardize characteristic protein components and to analyze alterations in mobility of these protein components, using a computerized densitometric technique. Sera values from dogs with lymphosarcomas, osteosarcomas, and mammary tumors were compared, using conventional methods of statistical analysis. Results indicate a statistical difference existed between mean values of EMR and alpha2-globulins of sera from dogs with tumors and those values from normal dogs. In addition, unique EMR and concentration of protein components were identified for dogs with lymphosarcomas, osteosarcomas, and mammary tumors.

Duke Scholars

Published In

Am J Vet Res

ISSN

0002-9645

Publication Date

September 1978

Volume

39

Issue

9

Start / End Page

1482 / 1486

Location

United States

Related Subject Headings

  • Veterinary Sciences
  • Osteosarcoma
  • Neoplasms
  • Mammary Glands, Animal
  • Male
  • Lymphoma, Non-Hodgkin
  • Female
  • Dogs
  • Dog Diseases
  • Bone Neoplasms
 

Citation

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Phillips, R. K., Dewhirst, M. W., Gillette, E. L., & Clow, D. J. (1978). Electrophoretic evaluation of sera from dogs with cancer. Am J Vet Res, 39(9), 1482–1486.
Phillips, R. K., M. W. Dewhirst, E. L. Gillette, and D. J. Clow. “Electrophoretic evaluation of sera from dogs with cancer.Am J Vet Res 39, no. 9 (September 1978): 1482–86.
Phillips RK, Dewhirst MW, Gillette EL, Clow DJ. Electrophoretic evaluation of sera from dogs with cancer. Am J Vet Res. 1978 Sep;39(9):1482–6.
Phillips, R. K., et al. “Electrophoretic evaluation of sera from dogs with cancer.Am J Vet Res, vol. 39, no. 9, Sept. 1978, pp. 1482–86.
Phillips RK, Dewhirst MW, Gillette EL, Clow DJ. Electrophoretic evaluation of sera from dogs with cancer. Am J Vet Res. 1978 Sep;39(9):1482–1486.

Published In

Am J Vet Res

ISSN

0002-9645

Publication Date

September 1978

Volume

39

Issue

9

Start / End Page

1482 / 1486

Location

United States

Related Subject Headings

  • Veterinary Sciences
  • Osteosarcoma
  • Neoplasms
  • Mammary Glands, Animal
  • Male
  • Lymphoma, Non-Hodgkin
  • Female
  • Dogs
  • Dog Diseases
  • Bone Neoplasms