Mark Wesley Dewhirst
Gustavo S. Montana Distinguished Professor Emeritus of Radiation Oncology
Mark W. Dewhirst, DVM, PhD is the Gustavo S. Montana Professor of Radiation Oncology and Vice Director for Basic Science in the Duke Cancer Institute. Dr. Dewhirst has research interests in tumor hypoxia, angiogenesis, hyperthermia and drug transport. He has spent 30 years studying causes of tumor hypoxia and the use of hyperthermia to treat cancer. In collaboration with Professor David Needham in the Pratt School of Engineering, he has developed a novel thermally sensitive drug carrying liposome that has been successfully translated to human clinical trials. He has utilized the thermal characteristics of this liposome to develop an MR imageable form that can accurately reflect drug concentrations in tumors, which then is related to the extent of anti-tumor effect in pre-clinical models. This property has been widely used by other investigators, world-wide, particularly in the area of high intensity focused ultrasound, where it would be possible to literally paint drug to a target zone and visualize this process in real time, during heating. For his work in this area, Dr. Dewhirst was named a Fellow in the AAAS. Dr. Dewhirst has well over 500 peer-reviewed publications, book chapters and reviews, with >20,000 citations and an H-index of 73. He has given named lectures at the University of Western Ontario, Thomas Jefferson University and the New Zealand Cancer Society. He was awarded the Failla Medal and Lecture at the Radiation Research Society in 2008, the Eugene Robinson award for excellence hyperthermia research in 1992 and a similar award from the European Society for Hyperthermic Oncology in 2009. He was named a fellow of ASTRO in 2009 and was awarded the prestigious Gold Medal from the same society in 2012. He is a Senior Editor of Cancer Research and Editor-in-Chief of the International Journal of Hyperthermia. He has mentored 24 graduate students, and many postdoctoral fellows, residents, junior faculty and medical students. He has been particularly skillful in assisting those he has mentored to obtain DOD and NIH fellowships, K awards and first R01 grants. His skill in mentoring has been recognized by the Duke Comprehensive Cancer Center, the Medical Physics Graduate Training programs and the School of Medicine, where he has received “Mentor of the Year” awards. In 2011 he was selected to become the first Associate Dean of Faculty Mentoring in the Duke School of Medicine. In this position, he is implementing a comprehensive program to enhance success in obtaining NIH funding. He graduated from the University of Arizona in 1971 with a degree in Chemistry and Colorado State University in 1975 and 1979 with DVM and PhD degrees, respectively.
Current Appointments & Affiliations
- Gustavo S. Montana Distinguished Professor Emeritus of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2019
- Professor Emeritus of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2019
- Associate Dean for Faculty Mentoring, School of Medicine, Duke University 2011
Contact Information
- 201 Med Sci Res Bldg, Research Drive, Durham, NC 27710
- Box 3455 Med Ctr, Durham, NC 27710
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mark.dewhirst@duke.edu
(919) 684-4180
- Background
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Education, Training, & Certifications
- Ph.D., Colorado State University 1979
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Previous Appointments & Affiliations
- Professor in Pathology, Pathology, Clinical Science Departments 1999 - 2020
- Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 1993 - 2019
- Gustavo S. Montana Distinguished Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2002 - 2019
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2002 - 2019
- Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2015 - 2018
- Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 1999 - 2010
- Assistant Professor in Pathology, Pathology, Clinical Science Departments 1994 - 1999
- Associate Professor in Radiation Oncology, Radiation Oncology, Clinical Science Departments 1988 - 1993
- Recognition
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In the News
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MAY 9, 2017 Duke Cancer Institute -
APR 20, 2016 The Scientist -
DEC 14, 2015 -
MAR 25, 2015 The New York Times -
JAN 22, 2014 WRAL -
JUL 3, 2013 Sydney Daily Telegraph
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Awards & Honors
- Research
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Selected Grants
- Proteomic Signatures of Space Radiation Induced Cardiovascular Degeneration awarded by National Aeronautics and Space Administration 2016 - 2022
- Characterization of Tumor Immunobiological Factors that Promote Lymphovascular Invasion and Dissemination in Locally Advanced Breast Cancer awarded by Department of Defense 2017 - 2022
- Preclinical Oxygen Imager to Model Efficient Cancer Treatment awarded by O2M Technologies, LLC 2019 - 2022
- Role of RBC Reactive Oxygen Species and Their Vicious Cycle in Sickle Vasculopathy awarded by National Institutes of Health 2017 - 2021
- Systemically administrered EGRFvIII-targeted bispecific antibody as an immunotherapeutic for glioblastoma. awarded by National Institutes of Health 2015 - 2019
- Dissecting mechanism(s) by which ionizing radiation promotes clonal expansion of premalignant cells in the thymus awarded by National Institutes of Health 2016 - 2018
- Duke CTSA (UL1) awarded by National Institutes of Health 2013 - 2018
- Optimization of radiofrequency ablation with electrically conductive particles awarded by National Institutes of Health 2015 - 2018
- The role of ERRalpha/PGC-1 in disease pathogenesis awarded by National Institutes of Health 2006 - 2018
- Luminescent Oxygen Nanosensors for Tumor Hypoxia Imaging awarded by University of Virginia - Charlottesville 2012 - 2017
- Effects of Exercise Training on Tumor Growth in Triple Negative Breast Cancer awarded by Memorial Sloan-Kettering Cancer Center 2014 - 2017
- A Quantitative Optical Sensor to Monitor Tumor Vascular Physiology awarded by Zenalux Biomedical, Inc. 2015 - 2016
- Janssen Research AGreement awarded by Janssen Research & Development, LLC 2014 - 2016
- HIF-1 driven therapeutic resistance mechanisms in chest wall recurrences of inflammatory breast cancer (IBC) awarded by Inflammatory Breast Cancer Research Foundation 2013 - 2016
- Targeting nuclear FGF receptor to improve chemotherapy response in triple-negative breast cancer awarded by Department of Defense 2013 - 2016
- Research Training In Neuro-Oncology awarded by National Institutes of Health 1998 - 2016
- Thermally Triggered Multivalent Targeting of Tumors awarded by National Institutes of Health 2007 - 2016
- BMX-001 as a Radio-Protector in Head and Neck Cancer Therapy awarded by BioMimetix Pharmaceutical, Inc. 2015 - 2016
- Thermally Targeted Drug Delivery by Elastin Biopolymers awarded by National Institutes of Health 2002 - 2016
- Cancer Biology Training Grant awarded by National Cancer Institute 1993 - 2016
- Radiation Therapy: Dissecting the Role of Stromal Cells in Tumor Control awarded by National Institutes of Health 2013 - 2016
- Detection of Novel Alternative Splicing Biomarkers of Hypoxia in Breast and Lung Tumors awarded by Rsna Research & Education Fund 2014 - 2015
- Heat and Radiation Effects on Tumor Microcirculation awarded by National Institutes of Health 1985 - 2015
- Harnessing the power of light to see and treat breast cancer awarded by United States Army Medical Research and Materiel Command 2009 - 2015
- Clinical Oncology Research Career Development Program awarded by National Institutes of Health 2009 - 2015
- 27-hydroxycholesterol as a link between obesity and breast cancer pathogenesis awarded by National Institutes of Health 2013 - 2014
- Resveratrol, Carbohydrate Restriction and Prostate Cancer Progression awarded by National Institutes of Health 2008 - 2014
- Truncated GLI1 In Glioblastoma awarded by National Institutes of Health 2014
- Modulation of the blood-tumor barrier through targeted suppression of claudin 5 awarded by National Institutes of Health 2011 - 2013
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
- The Use of Hyperthermia and Copper Chelation to Overcome Cisplatin Resistance awarded by National Institutes of Health 2011 - 2013
- Inhibition of metastasis-initiating cells by chimeric polypeptide nanoparticles awarded by National Institutes of Health 2010 - 2012
- Can Optical Spectroscopy Predict Early Treatment Response in Solid Tumors awarded by National Institutes of Health 2010 - 2012
- Nuclear EGFR Signaling Network in Human Cancer awarded by National Institutes of Health 2006 - 2012
- Molecular mechanisms of chemoresistance in breast cancer awarded by National Institutes of Health 2010 - 2012
- Small Animal PET / CT Molecular Imaging awarded by National Institutes of Health 2011 - 2012
- Investigation of Anti-Angiogenic Mechanisms Using Novel Imaging Techniques awarded by US Army Medical Research and Materiel Command 2009 - 2012
- The Role of PTEN in Endothelial Biology awarded by National Institutes of Health 2008 - 2012
- Image-Guided Radiation Therapy and Radiosurgery for Small Animals awarded by National Institutes of Health 2009 - 2011
- Hyperthermia and Perfusion Effects in Cancer Therapy awarded by National Institutes of Health 2005 - 2011
- Intravital point-scanning confocal microscope awarded by National Institutes of Health 2010 - 2011
- Accurate Models for Predicting Radiation-Induced Injury awarded by National Institutes of Health 2006 - 2011
- Role of XIAP in Therapeutic Resistance in Inflammatory Breast Cancer awarded by Dept. of the Army -- USAMRAA 2008 - 2010
- Research Training In Neuro-Oncology awarded by National Institutes of Health 2005 - 2010
- Functional Optical Coherence Tomography for Monitoring Drug Resistance in Cancer awarded by National Institutes of Health 2009 - 2010
- Hyperthermia and Perfusion Effects in Cancer Therapy awarded by National Institutes of Health 1987 - 2010
- Erythropoietin Receptors in Breast Cancer awarded by National Institutes of Health 2004 - 2010
- Training in Biomolecular and Tissue Engineering awarded by National Institutes of Health 2003 - 2009
- Stem Cell-Like Glioma Cells in Angiogenesis awarded by National Institutes of Health 2008 - 2009
- TGFbeta-PTEN Interactions in Glioma Biology & Therapy awarded by National Institutes of Health 2006 - 2008
- 13th International Congress of Radiation Research awarded by Department of Energy 2007 - 2008
- 13th International Congress of Radiation Research awarded by National Institutes of Health 2007 - 2008
- Biomarker Studies for Novel Anti-Cancer Agents awarded by National Institutes of Health 2003 - 2008
- Noninvasive Monitoring Glutathione Metabolism in Tumors awarded by National Institutes of Health 2006 - 2007
- Mechanism of hypoxia mediated radiation lung injury awarded by National Institutes of Health 2003 - 2007
- Activation of Sickle Red Cell Adhesion awarded by National Institutes of Health 2003 - 2007
- Imaging Alternative Splicing During Tumor Progression awarded by National Institutes of Health 2002 - 2007
- The Duke University Molecular Imaging Center awarded by National Institutes of Health 2001 - 2006
- Mentored Clinical Research Scholar Program awarded by National Institutes of Health 2002 - 2006
- Hyperthermia-mediated gene therapy approach for cancer awarded by National Institutes of Health 1999 - 2006
- Cancer Immunotherapy Targeting Endothelial Antigens awarded by National Institutes of Health 2003 - 2006
- The Role of Glucose Metabolism on Tumor PO2 awarded by National Institutes of Health 2003 - 2006
- The Role of Glucose and O2 Transport on Tumor PO2 awarded by National Institutes of Health 2000 - 2006
- Antiestrogenic Effects on Tumor Angiogenesis awarded by National Institutes of Health 2001 - 2006
- Measurement of Hypoxia in Non-Small Cell Lung Carcinoma awarded by National Institutes of Health 2002 - 2006
- New Clinical Biomarker for Cancer--Wound Angiogenesis awarded by National Institutes of Health 2000 - 2006
- Cell Viability in Implantable Diffusion Chambers awarded by National Institutes of Health 2000 - 2005
- same awarded by National Institutes of Health 1999 - 2005
- TIE2-Associated Molecular Targets in Tumor Vasculature awarded by National Institutes of Health 2002 - 2005
- Upgrade of a Shared Instrumentation Resource in the PSOE: The Laser Scanning Confocal Microscope awarded by Lord Foundation of North Carolina 2002 - 2005
- Molecular Imaging Center Planning Grant awarded by National Institutes of Health 2000 - 2004
- Heat and Radiation Effects on Tumor Microcirculation awarded by National Cancer Institute 1985 - 2004
- Hyperglycemia and Oxygen Breathing in Head & Neck Cancer awarded by National Institutes of Health 2000 - 2004
- Methods To Improve Camptothecan-Based Chemotherapy awarded by National Institutes of Health 1998 - 2001
- Predicting Human Tumor Response by 31p MRS awarded by National Institutes of Health 1995 - 2001
- Impaired Leukocyte/Endothelium Interactions In Tumors awarded by National Institutes of Health 1997 - 2000
- Hyperthermia And Perfusion Effects In Cancer Therapy awarded by National Institutes of Health 1997 - 1999
- Hyperthermia And Perfusion Effects In Cancer Therapy awarded by National Institutes of Health 1995 - 1999
- Hyperthermia And Perfusion Effects In Cancer Therapy awarded by National Institutes of Health 1987 - 1999
- Tek Kinase And Breast Tunor Angiogenesis awarded by National Institutes of Health 1995 - 1999
- Heat & Radiation Effects On Tumor Microcirculation awarded by National Institutes of Health 1997 - 1999
- Effects Of Heat And Radiation On Tumor awarded by National Institutes of Health 1996 - 1999
- Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1994 - 1999
- Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1993 - 1999
- Astatine And Iodine Radiolabeled Monoclonal Antibodies awarded by National Institutes of Health 1985 - 1999
- Cancer Center Core Support Grant awarded by National Institutes of Health 1976 - 1998
- Comprehensive Cancer Center Core Support Grant awarded by National Institutes of Health 1976 - 1998
- Comprehensive Cancer Center Core Support Grant awarded by National Institutes of Health 1976 - 1998
- Spore In Breast Cancer awarded by National Institutes of Health 1995 - 1998
- Spore In Breast Cancer awarded by National Institutes of Health 1995 - 1998
- Spore In Breast Cancer awarded by National Institutes of Health 1995 - 1998
- Tek Kinase And Breast Tumor Angiogenesis awarded by National Institutes of Health 1995 - 1998
- Effects Of Heat And Radiation On Tumor Microcirculation awarded by National Institutes of Health 1994 - 1996
- Effects Of Heat And Radiation On Tumor Microcirculation awarded by National Institutes of Health 1985 - 1996
- Hyperthermia And Perfusion Effects In Cancer Therapy awarded by National Institutes of Health 1993 - 1995
- Hyperthermia & Perfusion Effects In Cancer Therapy awarded by National Institutes of Health 1990 - 1995
- Heat And Radiation Effects In Tumor Microcirculation awarded by National Institutes of Health 1992 - 1993
- Response Of Canine Tumors To Nonstandard Fractionation awarded by National Institutes of Health 1987 - 1988
- Heat And Readiation Effects In Tumor Microcirculation awarded by National Institutes of Health 1986 - 1987
- Heat And Radiaition Effects In Tumor Microcirculation awarded by National Institutes of Health 1984 - 1985
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External Relationships
- Elmedix, Inc
- Hyperboost; Academic Medical Center, Amsterdam, The Netherlands
- Neo Therma
- Sensius
- Siva Therapeutics
- Taylor and Francis Group (Informa)
- Xenalux
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Bishawi, Muath, Franklin H. Lee, Dennis M. Abraham, Carolyn Glass, Stephanie J. Blocker, Daniel J. Cox, Zachary D. Brown, et al. “Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure.” Iscience 25, no. 4 (April 15, 2022): 104086. https://doi.org/10.1016/j.isci.2022.104086.Full Text Link to Item
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Dewhirst, Mark W., James R. Oleson, John Kirkpatrick, and Timothy W. Secomb. “Accurate Three-Dimensional Thermal Dosimetry and Assessment of Physiologic Response Are Essential for Optimizing Thermoradiotherapy.” Cancers (Basel) 14, no. 7 (March 27, 2022). https://doi.org/10.3390/cancers14071701.Full Text Link to Item
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Cao, X., J. Geradts, M. W. Dewhirst, and H. -. W. Lo. “Correction: Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.” Oncogene 41, no. 8 (February 2022): 1225–26. https://doi.org/10.1038/s41388-021-02043-6.Full Text Link to Item
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Boss, Mary-Keara, Remy Watts, Lauren G. Harrison, Sophie Hopkins, Lyndah Chow, Erin Trageser, Carina Easton, et al. “Immunologic Effects of Stereotactic Body Radiotherapy in Dogs with Spontaneous Tumors and the Impact of Intratumoral OX40/TLR Agonist Immunotherapy.” Int J Mol Sci 23, no. 2 (January 13, 2022). https://doi.org/10.3390/ijms23020826.Full Text Link to Item
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Garrett, Joy, Erin Metzger, Mark W. Dewhirst, Karen E. Pollok, John J. Turchi, Isabelle C. Le Poole, Kira Couch, et al. “Characterization and initial demonstration of in vivo efficacy of a novel heat-activated metalloenediyne anti-cancer agent.” Int J Hyperthermia 39, no. 1 (2022): 405–13. https://doi.org/10.1080/02656736.2021.2024280.Full Text Link to Item
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Borys, Nicholas, and Mark W. Dewhirst. “Drug development of lyso-thermosensitive liposomal doxorubicin: Combining hyperthermia and thermosensitive drug delivery.” Adv Drug Deliv Rev 178 (November 2021): 113985. https://doi.org/10.1016/j.addr.2021.113985.Full Text Link to Item
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Boss, Mary-Keara, Rebecca E. Oberley-Deegan, Ines Batinic-Haberle, Geoffrey A. Talmon, Jason A. Somarelli, Shengnan Xu, Elizabeth A. Kosmacek, et al. “Manganese Porphyrin and Radiotherapy Improves Local Tumor Response and Overall Survival in Orthotopic Murine Mammary Carcinoma Models.” Radiat Res 195, no. 2 (February 1, 2021): 128–39. https://doi.org/10.1667/RADE-20-00109.1.Full Text Link to Item
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Dewhirst, Mark. “Editors' awardees for 2021.” Int J Hyperthermia 38, no. 1 (2021): 795–97. https://doi.org/10.1080/02656736.2021.1930433.Full Text Link to Item
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Nief, Corrine, Robert Morhard, Erika Chelales, Daniel Adrianzen Alvarez, Ioanna Bourla Bs, Christopher T. Lam, Alan A. Sag, et al. “Polymer-assisted intratumoral delivery of ethanol: Preclinical investigation of safety and efficacy in a murine breast cancer model.” Plos One 16, no. 1 (2021): e0234535. https://doi.org/10.1371/journal.pone.0234535.Full Text Link to Item
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Bader, Samuel B., Mark W. Dewhirst, and Ester M. Hammond. “Cyclic Hypoxia: An Update on Its Characteristics, Methods to Measure It and Biological Implications in Cancer.” Cancers (Basel) 13, no. 1 (December 23, 2020). https://doi.org/10.3390/cancers13010023.Full Text Link to Item
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Rickard, Ashlyn G., Meng Zhuang, Christopher A. DeRosa, Xiaojie Zhang, Mark W. Dewhirst, Cassandra L. Fraser, and Gregory M. Palmer. “Dual-emissive, oxygen-sensing boron nanoparticles quantify oxygen consumption rate in breast cancer cells.” J Biomed Opt 25, no. 11 (November 2020). https://doi.org/10.1117/1.JBO.25.11.116504.Full Text Open Access Copy Link to Item
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Buhimschi, Alexandru D., David M. Gooden, Hongwu Jing, Diane R. Fels, Katherine S. Hansen, Wayne F. Beyer, Mark W. Dewhirst, Harold Walder, and Francis P. Gasparro. “Psoralen Derivatives with Enhanced Potency.” Photochem Photobiol 96, no. 5 (September 2020): 1014–31. https://doi.org/10.1111/php.13263.Full Text Link to Item
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Poirier, Yannick, Matthew D. Belley, Mark W. Dewhirst, Terry T. Yoshizumic, and Julian D. Down. “Transitioning from Gamma Rays to X Rays for Comparable Biomedical Research Irradiations: Energy Matters.” Radiat Res 193, no. 6 (June 1, 2020): 506–11. https://doi.org/10.1667/RADE-20-00039.1.Full Text Link to Item
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Muschel, Ruth J., Ester M. Hammond, and Mark W. Dewhirst. “A New Assay to Measure Intestinal Crypt Survival after Irradiation: Challenges and Opportunities.” Cancer Res 80, no. 5 (March 1, 2020): 927–28. https://doi.org/10.1158/0008-5472.CAN-19-4045.Full Text Link to Item
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Dewhirst, Mark W., and Rodney L. Page. “Editorial: Emerging Translational Opportunities in Comparative Oncology with Companion Canine Cancers.” Front Oncol 10 (2020): 270. https://doi.org/10.3389/fonc.2020.00270.Full Text Link to Item
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Dewhirst, Mark. “Editors' awardees for 2020.” Int J Hyperthermia 37, no. 1 (2020): 868–69. https://doi.org/10.1080/02656736.2020.1781392.Full Text Link to Item
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Dunne, Michael, James C. Evans, Mark W. Dewhirst, and Christine Allen. “The integration of hyperthermia and drug delivery.” Adv Drug Deliv Rev 163–164 (2020): 1–2. https://doi.org/10.1016/j.addr.2020.11.011.Full Text Link to Item
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Celik, Haydar, Paul Wakim, William F. Pritchard, Meryll Castro, Shelby Leonard, John W. Karanian, Mark W. Dewhirst, Riccardo Lencioni, and Bradford J. Wood. “Radiofrequency Ablation Duration per Tumor Volume May Correlate with Overall Survival in Solitary Hepatocellular Carcinoma Patients Treated with Radiofrequency Ablation Plus Lyso-Thermosensitive Liposomal Doxorubicin.” J Vasc Interv Radiol 30, no. 12 (December 2019): 1908–14. https://doi.org/10.1016/j.jvir.2019.04.023.Full Text Link to Item
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Celik, Haydar, Paul Wakim, William F. Pritchard, Meryll Castro, Shelby Leonard, John W. Karanian, Mark W. Dewhirst, Riccardo Lencioni, and Bradford J. Wood. “Radiofrequency Ablation Duration per Tumor Volume May Correlate with Overall Survival in Solitary Hepatocellular Carcinoma Patients Treated with Radiofrequency Ablation Plus Lyso-Thermosensitive Liposomal Doxorubicin.” Journal of Vascular and Interventional Radiology 30, no. 12 (December 1, 2019): 1908–14. https://doi.org/10.1016/i.jvir.2019.04.023.Full Text Open Access Copy Link to Item
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Gammon, Seth T., Federica Pisaneschi, Madhavi L. Bandi, Melinda G. Smith, Yuting Sun, Yi Rao, Florian Muller, et al. “Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [18F]FAZA PET In Vivo.” Cells 8, no. 12 (November 21, 2019). https://doi.org/10.3390/cells8121487.Full Text Link to Item
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Langsten, K. L., J. H. Kim, A. L. Sarver, M. Dewhirst, and J. F. Modiano. “Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment.” Frontiers in Oncology 9 (November 7, 2019). https://doi.org/10.3389/fonc.2019.01185.Full Text Open Access Copy
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Jolly, Mohit Kumar, Kathryn E. Ware, Shengnan Xu, Shivee Gilja, Samantha Shetler, Yanjun Yang, Xueyang Wang, et al. “E-Cadherin Represses Anchorage-Independent Growth in Sarcomas through Both Signaling and Mechanical Mechanisms.” Mol Cancer Res 17, no. 6 (June 2019): 1391–1402. https://doi.org/10.1158/1541-7786.MCR-18-0763.Full Text Link to Item
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Zhang, Xiaojie, Kathleen A. Ashcraft, Allison Betof Warner, Smita K. Nair, and Mark W. Dewhirst. “Can Exercise-Induced Modulation of the Tumor Physiologic Microenvironment Improve Antitumor Immunity?” Cancer Res 79, no. 10 (May 15, 2019): 2447–56. https://doi.org/10.1158/0008-5472.CAN-18-2468.Full Text Link to Item
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Ashcraft, Kathleen A., Johanna L. Hannan, Gary Eichenbaum, Xiaojie Zhang, Elena S. Pak, Austin M. Faught, Pranalee Patel, Mark W. Dewhirst, and Bridget F. Koontz. “Clarifying the Relative Impacts of Vascular and Nerve Injury That Culminate in Erectile Dysfunction in a Pilot Study Using a Rat Model of Prostate Irradiation and a Thrombopoietin Mimetic.” Int J Radiat Oncol Biol Phys 103, no. 5 (April 1, 2019): 1212–20. https://doi.org/10.1016/j.ijrobp.2018.11.064.Full Text Link to Item
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Alhaddad, Mehdi, Mark Dewhirst, Kenichi Soga, and Michael Devriendt. “A new photogrammetric system for high-precision monitoring of tunnel deformations.” Proceedings of the Institution of Civil Engineers Transport 172, no. 2 (April 2019): 81–93. https://doi.org/10.1680/jtran.18.00001.Full Text
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Zhu, Caigang, Martin Li, Thomas Vincent, Hannah L. Martin, Brian T. Crouch, Amy F. Martinez, Megan C. Madonna, Gregory M. Palmer, Mark W. Dewhirst, and Nimmi Ramanujam. “Simultaneous in vivo optical quantification of key metabolic and vascular endpoints reveals tumor metabolic diversity in murine breast tumor models.” J Biophotonics 12, no. 4 (April 2019): e201800372. https://doi.org/10.1002/jbio.201800372.Full Text Link to Item
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Dewhirst, M. W., Y. M. Mowery, J. B. Mitchell, M. K. Cherukuri, and T. W. Secomb. “Rationale for hypoxia assessment and amelioration for precision therapy and immunotherapy studies.” Journal of Clinical Investigation 129, no. 2 (February 1, 2019): 489–91. https://doi.org/10.1172/JCI12604.Full Text
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Dewhirst, Mark W., Yvonne M. Mowery, James B. Mitchell, Murali K. Cherukuri, and Timothy W. Secomb. “Rationale for hypoxia assessment and amelioration for precision therapy and immunotherapy studies.” J Clin Invest 129, no. 2 (February 1, 2019): 489–91. https://doi.org/10.1172/JCI126044.Full Text Link to Item
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Ashcraft, Kathleen A., Allison Betof Warner, Lee W. Jones, and Mark W. Dewhirst. “Exercise as Adjunct Therapy in Cancer.” Semin Radiat Oncol 29, no. 1 (January 2019): 16–24. https://doi.org/10.1016/j.semradonc.2018.10.001.Full Text Link to Item
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Rickard, Ashlyn G., Gregory M. Palmer, and Mark W. Dewhirst. “Clinical and Pre-clinical Methods for Quantifying Tumor Hypoxia.” Adv Exp Med Biol 1136 (2019): 19–41. https://doi.org/10.1007/978-3-030-12734-3_2.Full Text Link to Item
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Dewhirst, Mark W. “A potential solution for eliminating hypoxia as a cause for radioresistance.” Proc Natl Acad Sci U S A 115, no. 42 (October 16, 2018): 10548–50. https://doi.org/10.1073/pnas.1814212115.Full Text Link to Item
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Ashcraft, Kathleen A., Devin Miles, Mary E. Sunday, Kingshuk Roy Choudhury, Kenneth H. Young, Gregory M. Palmer, Pranalee Patel, et al. “Development and Preliminary Evaluation of a Murine Model of Chronic Radiation-Induced Proctitis.” Int J Radiat Oncol Biol Phys 101, no. 5 (August 1, 2018): 1194–1201. https://doi.org/10.1016/j.ijrobp.2018.04.061.Full Text Link to Item
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Ashcraft, Kathleen A., Kingshuk Roy Choudhury, Sam R. Birer, Hansford C. Hendargo, Pranalee Patel, Gary Eichenbaum, and Mark W. Dewhirst. “Application of a Novel Murine Ear Vein Model to Evaluate the Effects of a Vascular Radioprotectant on Radiation-Induced Vascular Permeability and Leukocyte Adhesion.” Radiat Res 190, no. 1 (July 2018): 12–21. https://doi.org/10.1667/RR14896.1.Full Text Link to Item
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Zhu, Caigang, Hannah L. Martin, Brian T. Crouch, Amy F. Martinez, Martin Li, Gregory M. Palmer, Mark W. Dewhirst, and Nimmi Ramanujam. “Near-simultaneous quantification of glucose uptake, mitochondrial membrane potential, and vascular parameters in murine flank tumors using quantitative diffuse reflectance and fluorescence spectroscopy.” Biomed Opt Express 9, no. 7 (July 1, 2018): 3399–3412. https://doi.org/10.1364/BOE.9.003399.Full Text Link to Item
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Oldham, Mark, Suk W. Yoon, Justus Adamson, Xiaofeng Zhang, Peter Fecci, and Mark Dewhirst. “In Reply to Pratx and Kapp.” Int J Radiat Oncol Biol Phys 101, no. 2 (June 1, 2018): 495–96. https://doi.org/10.1016/j.ijrobp.2018.02.018.Full Text Link to Item
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Palmer, Gregory M., Hengtao Zhang, Chen-Ting Lee, Husam Mikati, Joseph A. Herbert, Marlee Krieger, Jesko von Windheim, et al. “Assessing effects of pressure on tumor and normal tissue physiology using an automated self-calibrated, pressure-sensing probe for diffuse reflectance spectroscopy.” J Biomed Opt 23, no. 5 (May 2018): 1–8. https://doi.org/10.1117/1.JBO.23.5.057004.Full Text Link to Item
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Dewhirst, Mark W., and David Kirsch. “Technological Advances, Biologic Rationales, and the Associated Success of Chemotherapy With Hyperthermia in Improved Outcomes in Patients With Sarcoma.” Jama Oncol 4, no. 4 (April 1, 2018): 493–94. https://doi.org/10.1001/jamaoncol.2017.4941.Full Text Link to Item
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Martinez, Amy F., Samuel S. McCachren, Marianne Lee, Helen A. Murphy, Caigang Zhu, Brian T. Crouch, Hannah L. Martin, et al. “Metaboloptics: Visualization of the tumor functional landscape via metabolic and vascular imaging.” Sci Rep 8, no. 1 (March 8, 2018): 4171. https://doi.org/10.1038/s41598-018-22480-w.Full Text Link to Item
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Yoon, Suk W., Vadim Tsvankin, Zachary Shrock, Boyu Meng, Xiaofeng Zhang, Mark Dewhirst, Peter Fecci, Justus Adamson, and Mark Oldham. “Enhancing Radiation Therapy Through Cherenkov Light-Activated Phototherapy.” Int J Radiat Oncol Biol Phys 100, no. 3 (March 1, 2018): 794–801. https://doi.org/10.1016/j.ijrobp.2017.11.013.Full Text Open Access Copy Link to Item
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Dewhirst, Mark. “Concurrent tracking of anatomy and metabolism.” Nat Biomed Eng 2, no. 2 (February 2018): 54–55. https://doi.org/10.1038/s41551-018-0196-z.Full Text Link to Item
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Mastria, Eric M., Leon Y. Cai, Matthew J. Kan, Xinghai Li, Jeffrey L. Schaal, Steven Fiering, Michael D. Gunn, Mark W. Dewhirst, Smita K. Nair, and Ashutosh Chilkoti. “Nanoparticle formulation improves doxorubicin efficacy by enhancing host antitumor immunity.” J Control Release 269 (January 10, 2018): 364–73. https://doi.org/10.1016/j.jconrel.2017.11.021.Full Text Link to Item
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Lu, Min, Sydney M. Sanderson, Amelia Zessin, Kathleen A. Ashcraft, Lee W. Jones, Mark W. Dewhirst, Jason W. Locasale, and David S. Hsu. “Exercise inhibits tumor growth and central carbon metabolism in patient-derived xenograft models of colorectal cancer.” Cancer Metab 6 (2018): 14. https://doi.org/10.1186/s40170-018-0190-7.Full Text Link to Item
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Hu, Fangyao, Hannah Martin, Amy Martinez, Jeffrey Everitt, Alaattin Erkanli, Walter T. Lee, Mark Dewhirst, and Nimmi Ramanujam. “Distinct Angiogenic Changes during Carcinogenesis Defined by Novel Label-Free Dark-Field Imaging in a Hamster Cheek Pouch Model.” Cancer Res 77, no. 24 (December 15, 2017): 7109–19. https://doi.org/10.1158/0008-5472.CAN-17-1058.Full Text Link to Item
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Dewhirst, Mark W., and Timothy W. Secomb. “Transport of drugs from blood vessels to tumour tissue.” Nat Rev Cancer 17, no. 12 (December 2017): 738–50. https://doi.org/10.1038/nrc.2017.93.Full Text Link to Item
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Glass, Oliver K., Michelle Bowie, Julie Fuller, David Darr, Jerry Usary, Keara Boss, Kingshuk Roy Choudhury, et al. “Differential response to exercise in claudin-low breast cancer.” Oncotarget 8, no. 60 (November 24, 2017): 100989–4. https://doi.org/10.18632/oncotarget.21054.Full Text Open Access Copy Link to Item
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Lai, Thung-S, Robert A. Lindberg, Hua-Lin Zhou, Zishan A. Haroon, Mark W. Dewhirst, Alfred Hausladen, Y. -. L. Juang, Jonathan S. Stamler, and Charles S. Greenberg. “Endothelial cell-surface tissue transglutaminase inhibits neutrophil adhesion by binding and releasing nitric oxide.” Sci Rep 7, no. 1 (November 23, 2017): 16163. https://doi.org/10.1038/s41598-017-16342-0.Full Text Link to Item
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Freel, Stephanie A., Paige C. Smith, Ebony N. Burns, Joanna B. Downer, Ann J. Brown, and Mark W. Dewhirst. “Multidisciplinary Mentoring Programs to Enhance Junior Faculty Research Grant Success.” Acad Med 92, no. 10 (October 2017): 1410–15. https://doi.org/10.1097/ACM.0000000000001620.Full Text Link to Item
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Hofmann, Christina L., Melanie C. O’Sullivan, Alexandre Detappe, Yingjie Yu, Xi Yang, Wei Qi, Chelsea D. Landon, et al. “NIR-emissive PEG-b-TCL micelles for breast tumor imaging and minimally invasive pharmacokinetic analysis.” Nanoscale 9, no. 36 (September 21, 2017): 13465–76. https://doi.org/10.1039/c7nr02363d.Full Text Link to Item
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Bindra, Ranjit S., Anthony J. Chalmers, Sydney Evans, and Mark Dewhirst. “GBM radiosensitizers: dead in the water…or just the beginning?” J Neurooncol 134, no. 3 (September 2017): 513–21. https://doi.org/10.1007/s11060-017-2427-7.Full Text Link to Item
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Morhard, Robert, Corrine Nief, Carlos Barrero Castedo, Fangyao Hu, Megan Madonna, Jenna L. Mueller, Mark W. Dewhirst, David F. Katz, and Nirmala Ramanujam. “Development of enhanced ethanol ablation as an alternative to surgery in treatment of superficial solid tumors.” Sci Rep 7, no. 1 (August 18, 2017): 8750. https://doi.org/10.1038/s41598-017-09371-2.Full Text Link to Item
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Zhang, Xiaofeng, Sai Kit Lam, Gregory Palmer, Shiva Das, Mark Oldham, and Mark Dewhirst. “Noninvasive measurement of tissue blood oxygenation with Cerenkov imaging during therapeutic radiation delivery.” Opt Lett 42, no. 16 (August 15, 2017): 3101–4. https://doi.org/10.1364/OL.42.003101.Full Text Open Access Copy Link to Item
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Boss, M. K., M. W. Dewhirst, R. S. Sampaio, A. Bennett, A. Tovmasyan, K. G. Berman, A. W. Beaven, et al. “Potential for a novel manganese porphyrin compound as adjuvant canine lymphoma therapy.” Cancer Chemother Pharmacol 80, no. 2 (August 2017): 421–31. https://doi.org/10.1007/s00280-017-3372-z.Full Text Link to Item
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Lee, Chen-Ting, Yingchun Zhou, Kingshuk Roy-Choudhury, Sharareh Siamakpour-Reihani, Kenneth Young, Peter Hoang, John P. Kirkpatrick, Jen-Tsan Chi, Mark W. Dewhirst, and Janet K. Horton. “Subtype-Specific Radiation Response and Therapeutic Effect of FAS Death Receptor Modulation in Human Breast Cancer.” Radiat Res 188, no. 2 (August 2017): 169–80. https://doi.org/10.1667/RR14664.1.Full Text Link to Item
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Birer, Samuel R., Chen-Ting Lee, Kingshuk Roy Choudhury, Kenneth H. Young, Ivan Spasojevic, Ines Batinic-Haberle, James D. Crapo, Mark W. Dewhirst, and Kathleen A. Ashcraft. “Inhibition of the Continuum of Radiation-Induced Normal Tissue Injury by a Redox-Active Mn Porphyrin.” Radiat Res 188, no. 1 (July 2017): 94–104. https://doi.org/10.1667/RR14757.1.S1.Full Text Link to Item
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Arora, Jay, Scott J. Sauer, Michael Tarpley, Peter Vermeulen, Charlotte Rypens, Steven Van Laere, Kevin P. Williams, Gayathri R. Devi, and Mark W. Dewhirst. “Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies.” Oncotarget 8, no. 16 (April 18, 2017): 25848–63. https://doi.org/10.18632/oncotarget.15667.Full Text Link to Item
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Arora, Jay, Scott J. Sauer, Michael Tarpley, Peter Vermeulen, Charlotte Rypens, Steven Van Laere, Kevin P. Williams, Gayathri R. Devi, and Mark W. Dewhirst. “Inflammatory breast cancer tumor emboli express high levels of anti-apoptotic proteins: use of a quantitative high content and high-throughput 3D IBC spheroid assay to identify targeting strategies.” Oncotarget 8, no. 16 (April 18, 2017): 25848–63.Link to Item
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Masko, Elizabeth M., Mahmoud A. Alfaqih, Keith R. Solomon, William T. Barry, Christopher B. Newgard, Michael J. Muehlbauer, Nikolaos A. Valilis, et al. “Evidence for Feedback Regulation Following Cholesterol Lowering Therapy in a Prostate Cancer Xenograft Model.” Prostate 77, no. 5 (April 2017): 446–57. https://doi.org/10.1002/pros.23282.Full Text Link to Item
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Bhattacharyya, Jayanta, Isaac Weitzhandler, Shihan Bryan Ho, Jonathan R. McDaniel, Xinghai Li, Lei Tang, Jinyao Liu, Mark Dewhirst, and Ashutosh Chilkoti. “Encapsulating a Hydrophilic Chemotherapeutic into Rod-like Nanoparticles of a Genetically Encoded Asymmetric Triblock Polypeptide Improves its Efficacy.” Adv Funct Mater 27, no. 12 (March 24, 2017). https://doi.org/10.1002/adfm.201605421.Full Text Link to Item
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Hu, Fangyao, Karthik Vishwanath, Joseph K. Salama, Alaattin Erkanli, Bercedis Peterson, James R. Oleson, Walter T. Lee, David M. Brizel, Nimmi Ramanujam, and Mark W. Dewhirst. “Oxygen and Perfusion Kinetics in Response to Fractionated Radiation Therapy in FaDu Head and Neck Cancer Xenografts Are Related to Treatment Outcome.” Int J Radiat Oncol Biol Phys 96, no. 2 (October 1, 2016): 462–69. https://doi.org/10.1016/j.ijrobp.2016.06.007.Full Text Link to Item
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Koontz, B. F., K. Ashcraft, A. Faught, P. Patel, E. Woska, L. Mao, and M. W. Dewhirst. “Etiology of Radiation-Induced Erectile Dysfunction: Vessel or Nerve?” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): E590–91. https://doi.org/10.1016/j.ijrobp.2016.06.2107.Full Text Link to Item
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Geer Wallace, M Ariel, Do-Yeon Kwon, Douglas H. Weitzel, Chen-Ting Lee, Tesia N. Stephenson, Jen-Tsan Chi, Robert A. Mook, Mark W. Dewhirst, Jiyong Hong, and Michael C. Fitzgerald. “Discovery of Manassantin A Protein Targets Using Large-Scale Protein Folding and Stability Measurements.” J Proteome Res 15, no. 8 (August 5, 2016): 2688–96. https://doi.org/10.1021/acs.jproteome.6b00237.Full Text Link to Item
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Ashcraft, Kathleen A., Ralph M. Peace, Allison S. Betof, Mark W. Dewhirst, and Lee W. Jones. “Efficacy and Mechanisms of Aerobic Exercise on Cancer Initiation, Progression, and Metastasis: A Critical Systematic Review of In Vivo Preclinical Data.” Cancer Res 76, no. 14 (July 15, 2016): 4032–50. https://doi.org/10.1158/0008-5472.CAN-16-0887.Full Text Link to Item
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Coleman, C Norman, Geoff S. Higgins, J Martin Brown, Michael Baumann, David G. Kirsch, Henning Willers, Pataje G. S. Prasanna, Mark W. Dewhirst, Eric J. Bernhard, and Mansoor M. Ahmed. “Improving the Predictive Value of Preclinical Studies in Support of Radiotherapy Clinical Trials.” Clin Cancer Res 22, no. 13 (July 1, 2016): 3138–47. https://doi.org/10.1158/1078-0432.CCR-16-0069.Full Text Link to Item
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Dewhirst, Mark W., and Kathleen A. Ashcraft. “Implications of Increase in Vascular Permeability in Tumors by VEGF: A Commentary on the Pioneering Work of Harold Dvorak.” Cancer Res 76, no. 11 (June 1, 2016): 3118–20. https://doi.org/10.1158/0008-5472.CAN-16-1292.Full Text Link to Item
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Heijden, Antoine G. van der, and Mark W. Dewhirst. “Effects of hyperthermia in neutralising mechanisms of drug resistance in non-muscle-invasive bladder cancer.” Int J Hyperthermia 32, no. 4 (June 2016): 434–45. https://doi.org/10.3109/02656736.2016.1155761.Full Text Link to Item
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Weitzel, Douglas H., Artak Tovmasyan, Kathleen A. Ashcraft, Alina Boico, Samuel R. Birer, Kingshuk Roy Choudhury, James Herndon, et al. “Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier.” Environ Mol Mutagen 57, no. 5 (June 2016): 372–81. https://doi.org/10.1002/em.22021.Full Text Link to Item
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Yoon, S., B. Langloss, M. Boss, S. Birer, M. Dewhirst, and M. Oldham. “SU-G-IeP4-08: Initial Investigations of Up-Converting Nanoparticles (UCNP) for 3D Tissue Imaging in Optical-ECT.” Med Phys 43, no. 6 (June 2016): 3679. https://doi.org/10.1118/1.4957103.Full Text Link to Item
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Yoon, S., M. Boss, S. Birer, M. Dewhirst, and M. Oldham. “TH-EF-207A-06: High-Resolution Optical-CT/ECT Imaging of Unstained Mice Femur, Brain, Spleen, and Tumor.” Med Phys 43, no. 6 (June 2016): 3901. https://doi.org/10.1118/1.4958278.Full Text Link to Item
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Oldham, M., S. Yoon, B. Meng, Z. Fathi, W. Beyer, J. Adamson, D. Alcorta, et al. “WE-FG-BRA-01: Cancer Treatment Utilizing Photo-Activation of Psoralen with KV X-Rays.” Med Phys 43, no. 6 (June 2016): 3823. https://doi.org/10.1118/1.4957901.Full Text Link to Item
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Park, Sunghee, Ching-Yi Chang, Rachid Safi, Xiaojing Liu, Robert Baldi, Jeff S. Jasper, Grace R. Anderson, et al. “ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer.” Cell Rep 15, no. 2 (April 12, 2016): 323–35. https://doi.org/10.1016/j.celrep.2016.03.026.Full Text Link to Item
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Dewhirst, Mark W., and Samuel R. Birer. “Oxygen-Enhanced MRI Is a Major Advance in Tumor Hypoxia Imaging.” Cancer Res 76, no. 4 (February 15, 2016): 769–72. https://doi.org/10.1158/0008-5472.CAN-15-2818.Full Text Link to Item
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LeBlanc, Amy K., Matthew Breen, Peter Choyke, Mark Dewhirst, Timothy M. Fan, Daniel L. Gustafson, Lee J. Helman, et al. “Perspectives from man's best friend: National Academy of Medicine's Workshop on Comparative Oncology.” Sci Transl Med 8, no. 324 (February 3, 2016): 324ps5. https://doi.org/10.1126/scitranslmed.aaf0746.Full Text Link to Item
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Dewhirst, Mark W., Chen-Ting Lee, and Kathleen A. Ashcraft. “The future of biology in driving the field of hyperthermia.” Int J Hyperthermia 32, no. 1 (2016): 4–13. https://doi.org/10.3109/02656736.2015.1091093.Full Text Link to Item
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Oldham, Mark, Paul Yoon, Zak Fathi, Wayne F. Beyer, Justus Adamson, Leihua Liu, David Alcorta, et al. “X-Ray Psoralen Activated Cancer Therapy (X-PACT).” Plos One 11, no. 9 (2016): e0162078. https://doi.org/10.1371/journal.pone.0162078.Full Text Open Access Copy Link to Item
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Tovmasyan, Artak, Romulo S. Sampaio, Mary-Keara Boss, Jacqueline C. Bueno-Janice, Bader H. Bader, Milini Thomas, Julio S. Reboucas, et al. “Anticancer therapeutic potential of Mn porphyrin/ascorbate system.” Free Radic Biol Med 89 (December 2015): 1231–47. https://doi.org/10.1016/j.freeradbiomed.2015.10.416.Full Text Link to Item
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Ashcraft, Kathleen A., Mary-Keara Boss, Artak Tovmasyan, Kingshuk Roy Choudhury, Andrew N. Fontanella, Kenneth H. Young, Gregory M. Palmer, et al. “Novel Manganese-Porphyrin Superoxide Dismutase-Mimetic Widens the Therapeutic Margin in a Preclinical Head and Neck Cancer Model.” Int J Radiat Oncol Biol Phys 93, no. 4 (November 15, 2015): 892–900. https://doi.org/10.1016/j.ijrobp.2015.07.2283.Full Text Open Access Copy Link to Item
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Horton, Janet K., Sharareh Siamakpour-Reihani, Chen-Ting Lee, Ying Zhou, Wei Chen, Joseph Geradts, Diane R. Fels, et al. “FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target.” Radiat Res 184, no. 5 (November 2015): 456–69. https://doi.org/10.1667/RR14089.1.Full Text Link to Item
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Kwon, Do-Yeon, Hye Eun Lee, Douglas H. Weitzel, Kyunghye Park, Sun Hee Lee, Chen-Ting Lee, Tesia N. Stephenson, et al. “Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α Inhibition.” J Med Chem 58, no. 19 (October 8, 2015): 7659–71. https://doi.org/10.1021/acs.jmedchem.5b01220.Full Text Link to Item
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Belley, Matthew D., Kathleen A. Ashcraft, Chen-Ting Lee, Milton R. Cornwall-Brady, Jane-Jane Chen, Rathnayaka Gunasingha, Markus Burkhart, Mark Dewhirst, Terry T. Yoshizumi, and Julian D. Down. “Microdosimetric and Biological Effects of Photon Irradiation at Different Energies in Bone Marrow.” Radiat Res 184, no. 4 (October 2015): 378–91. https://doi.org/10.1667/RR14095.1.Full Text Link to Item
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Siamakpour-Reihani, Sharareh, Kouros Owzar, Chen Jiang, Taylor Turner, Yiwen Deng, Sarah M. Bean, Janet K. Horton, et al. “Prognostic significance of differential expression of angiogenic genes in women with high-grade serous ovarian carcinoma.” Gynecol Oncol 139, no. 1 (October 2015): 23–29. https://doi.org/10.1016/j.ygyno.2015.08.001.Full Text Link to Item
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Horton, Janet K., Rachel C. Blitzblau, Sua Yoo, Joseph Geradts, Zheng Chang, Jay A. Baker, Gregory S. Georgiade, et al. “Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers.” Int J Radiat Oncol Biol Phys 92, no. 4 (July 15, 2015): 846–55. https://doi.org/10.1016/j.ijrobp.2015.03.007.Full Text Link to Item
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Mastria, Eric M., Mingnan Chen, Jonathan R. McDaniel, Xinghai Li, Jinho Hyun, Mark W. Dewhirst, and Ashutosh Chilkoti. “Doxorubicin-conjugated polypeptide nanoparticles inhibit metastasis in two murine models of carcinoma.” J Control Release 208 (June 28, 2015): 52–58. https://doi.org/10.1016/j.jconrel.2015.01.033.Full Text Link to Item
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Choudhury, Kingshuk Roy, Stephen T. Keir, Kathleen A. Ashcraft, Mary-Keara Boss, and Mark W. Dewhirst. “Dynamic treatment effect (DTE) curves reveal the mode of action for standard and experimental cancer therapies.” Oncotarget 6, no. 16 (June 10, 2015): 14656–68. https://doi.org/10.18632/oncotarget.4141.Full Text Link to Item
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Malcolm, J., K. Boss, M. Dewhirst, and M. Oldham. “WE-EF-BRA-11: Precision Partial-Tumor Irradiation of Dorsal Rodent Mammary Tumors.” Med Phys 42, no. 6 (June 2015): 3677. https://doi.org/10.1118/1.4925990.Full Text Link to Item
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Siamakpour-Reihani, Sharareh, Kouros Owzar, Chen Jiang, Peter M. Scarbrough, Oana I. Craciunescu, Janet K. Horton, Holly K. Dressman, Kimberly L. Blackwell, and Mark W. Dewhirst. “Genomic profiling in locally advanced and inflammatory breast cancer and its link to DCE-MRI and overall survival.” Int J Hyperthermia 31, no. 4 (June 2015): 386–95. https://doi.org/10.3109/02656736.2015.1016557.Full Text Link to Item
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Zhang, Minsi, Qiong Qiu, Zhizhong Li, Mohit Sachdeva, Hooney Min, Diana M. Cardona, Thomas F. DeLaney, et al. “HIF-1 Alpha Regulates the Response of Primary Sarcomas to Radiation Therapy through a Cell Autonomous Mechanism.” Radiat Res 183, no. 6 (June 2015): 594–609. https://doi.org/10.1667/RR14016.1.Full Text Link to Item
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Boss, Mary-Keara, and Mark Dewhirst. “A tribute to Philip Marcus and the development of the clonogenic assay.” Radiat Res 183, no. 5 (May 2015): 497–500. https://doi.org/10.1667/rr14048.1.Full Text Link to Item
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Betof, Allison S., Christopher D. Lascola, Douglas Weitzel, Chelsea Landon, Peter M. Scarbrough, Gayathri R. Devi, Gregory Palmer, Lee W. Jones, and Mark W. Dewhirst. “Modulation of murine breast tumor vascularity, hypoxia and chemotherapeutic response by exercise.” J Natl Cancer Inst 107, no. 5 (May 2015). https://doi.org/10.1093/jnci/djv040.Full Text Open Access Copy Link to Item
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Dewhirst, M. W. “Exercise Affects Tumor Growth and Drug Response in a Mouse Model of Breast Cancer.” Journal of the National Cancer Institute 107, no. 5 (May 1, 2015). https://doi.org/10.1093/JNCI/DJV089.Full Text
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Chitneni, Satish K., Gerald T. Bida, Michael R. Zalutsky, and Mark W. Dewhirst. “Reply: Pharmacokinetic and Pharmacodynamic Modifiers of EF5 Uptake and Binding.” J Nucl Med 56, no. 4 (April 2015): 653–54. https://doi.org/10.2967/jnumed.115.154054.Full Text Link to Item
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Samonina-Kosicka, Jelena, Douglas H. Weitzel, Christina L. Hofmann, Hansford Hendargo, Gabi Hanna, Mark W. Dewhirst, Gregory M. Palmer, and Cassandra L. Fraser. “Luminescent difluoroboron β-diketonate PEG-PLA oxygen nanosensors for tumor imaging.” Macromol Rapid Commun 36, no. 7 (April 2015): 694–99. https://doi.org/10.1002/marc.201500022.Full Text Link to Item
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Dewhirst, Mark W. “From the guest editor: an integrated multidisciplinary view of tumor metabolism.” Cancer J 21, no. 2 (March 2015): 47–48. https://doi.org/10.1097/PPO.0000000000000108.Full Text Link to Item
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Payen, Valéry L., Lucie Brisson, Mark W. Dewhirst, and Pierre Sonveaux. “Common responses of tumors and wounds to hypoxia.” Cancer J 21, no. 2 (March 2015): 75–87. https://doi.org/10.1097/PPO.0000000000000098.Full Text Link to Item
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Turley, Ryan S., Yoshihiro Tokuhisa, Hiroaki Toshimitsu, Michael E. Lidsky, James C. Padussis, Andrew Fontanella, Wanleng Deng, et al. “Targeting N-cadherin increases vascular permeability and differentially activates AKT in melanoma.” Ann Surg 261, no. 2 (February 2015): 368–77. https://doi.org/10.1097/SLA.0000000000000635.Full Text Link to Item
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Fontanella, Andrew N., Mary-Keara Boss, Michael Hadsell, Jian Zhang, Thies Schroeder, Katherine G. Berman, Mark W. Dewhirst, Sha Chang, and Gregory M. Palmer. “Effects of high-dose microbeam irradiation on tumor microvascular function and angiogenesis.” Radiat Res 183, no. 2 (February 2015): 147–58. https://doi.org/10.1667/RR13712.1.Full Text Link to Item
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Carpenter, R. L., I. Paw, M. W. Dewhirst, and H. -. W. Lo. “Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells.” Oncogene 34, no. 5 (January 29, 2015): 546–57. https://doi.org/10.1038/onc.2013.582.Full Text Link to Item
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Weitzel, Douglas H., Artak Tovmasyan, Kathleen A. Ashcraft, Zrinka Rajic, Tin Weitner, Chunlei Liu, Wei Li, et al. “Radioprotection of the brain white matter by Mn(III) n-Butoxyethylpyridylporphyrin-based superoxide dismutase mimic MnTnBuOE-2-PyP5+.” Mol Cancer Ther 14, no. 1 (January 2015): 70–79. https://doi.org/10.1158/1535-7163.MCT-14-0343.Full Text Link to Item
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Blueschke, Gert, Gabi Hanna, Andrew N. Fontanella, Gregory M. Palmer, Alina Boico, Hooney Min, Mark W. Dewhirst, David C. Irwin, Yulin Zhao, and Thies Schroeder. “Automated measurement of microcirculatory blood flow velocity in pulmonary metastases of rats.” J Vis Exp, no. 93 (November 30, 2014): e51630. https://doi.org/10.3791/51630.Full Text Link to Item
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Tovmasyan, Artak, Emily R. H. Roberts, Yuliana Yuliana, Sinisa Haberle, Mary-Keara Boss, Talaignair N. Venkatraman, Christopher Lascola, et al. “The Role of Ascorbate in Therapeutic Actions of Cationic Mn Porphyrin-Based SOD Mimics.” Free Radical Biology and Medicine 76 (November 2014): S94–95. https://doi.org/10.1016/j.freeradbiomed.2014.10.327.Full Text
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Horton, Janet K., Mark W. Dewhirst, Sharareh Siamakpour-Reihani, Yingchun Zhou, Joseph Geradts, Jen-Tsan Ashley Chi, and Wei Chen. “Changes in Gene Expression After Radiation in Human Breast Cancers: A Guide to Predicting and Modulating Radiation Response.” Journal of Womens Health 23, no. 10 (October 1, 2014): 861–861.Link to Item
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Jones, Leslie Braziel, Timothy W. Secomb, Mark W. Dewhirst, and Ardith W. El-Kareh. “The additive damage model: a mathematical model for cellular responses to drug combinations.” J Theor Biol 357 (September 21, 2014): 10–20. https://doi.org/10.1016/j.jtbi.2014.04.032.Full Text Link to Item
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Viglianti, Benjamin L., Mark W. Dewhirst, R. J. Boruta, Ji-Young Park, Chelsea Landon, Andrew N. Fontanella, Jing Guo, Ashley Manzoor, Christina L. Hofmann, and Gregory M. Palmer. “Systemic anti-tumour effects of local thermally sensitive liposome therapy.” Int J Hyperthermia 30, no. 6 (September 2014): 385–92. https://doi.org/10.3109/02656736.2014.944587.Full Text Link to Item
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Viglianti, Benjamin L., Mark W. Dewhirst, John P. Abraham, John M. Gorman, and Eph M. Sparrow. “Rationalization of thermal injury quantification methods: application to skin burns.” Burns 40, no. 5 (August 2014): 896–902. https://doi.org/10.1016/j.burns.2013.12.005.Full Text Link to Item
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Wang, Chu, Matthew D. Belley, Nelson J. Chao, Mark W. Dewhirst, and Terry Yoshizumi. “Verification of a novel method for tube voltage constancy measurement of orthovoltage x-ray irradiators.” Med Phys 41, no. 8 (August 2014): 084101. https://doi.org/10.1118/1.4889778.Full Text Link to Item
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Zagar, Timothy M., Zeljko Vujaskovic, Silvia Formenti, Hope Rugo, Franco Muggia, Brigid O’Connor, Robert Myerson, et al. “Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer.” Int J Hyperthermia 30, no. 5 (August 2014): 285–94. https://doi.org/10.3109/02656736.2014.936049.Full Text Link to Item
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Lee, Chen-Ting, Mary-Keara Boss, and Mark W. Dewhirst. “Imaging tumor hypoxia to advance radiation oncology.” Antioxid Redox Signal 21, no. 2 (July 10, 2014): 313–37. https://doi.org/10.1089/ars.2013.5759.Full Text Link to Item
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Pries, Axel R., Bettina Reglin, Mark W. Dewhirst, and Timothy W. Secomb. “Making microvascular networks work: angiogenesis, remodeling and pruning.” Angiogenesis 17, no. 3 (July 1, 2014): 716–716.Link to Item
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Chitneni, Satish K., Gerald T. Bida, Michael R. Zalutsky, and Mark W. Dewhirst. “Comparison of the Hypoxia PET Tracer (18)F-EF5 to Immunohistochemical Marker EF5 in 3 Different Human Tumor Xenograft Models.” J Nucl Med 55, no. 7 (July 2014): 1192–97. https://doi.org/10.2967/jnumed.114.137448.Full Text Link to Item
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Yu, Bing, Amy Shah, Bingqing Wang, Narasimhan Rajaram, Quanli Wang, Nirmala Ramanujam, Gregory M. Palmer, and Mark W. Dewhirst. “Measuring tumor cycling hypoxia and angiogenesis using a side-firing fiber optic probe.” J Biophotonics 7, no. 7 (July 2014): 552–64. https://doi.org/10.1002/jbio.201200187.Full Text Link to Item
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Boss, Mary-Keara, Robert Bristow, and Mark W. Dewhirst. “Linking the history of radiation biology to the hallmarks of cancer.” Radiat Res 181, no. 6 (June 2014): 561–77. https://doi.org/10.1667/RR13675.1.Full Text Link to Item
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Chang, S., A. Fontanella, M. Boss, J. Zhang, M. Hadsell, T. Schroeder, K. Berman, G. Palmer, and M. Dewhirst. “WE-E-BRE-06: High-Dose Microbeam Radiation Induces Different Responses in Tumor Microenvironment Compared to Conventional Seamless Radiation in Window Chamber Tumor Models.” Med Phys 41, no. 6 (June 2014): 505. https://doi.org/10.1118/1.4889435.Full Text Link to Item
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McDaniel, Jonathan R., Sarah R. MacEwan, Xinghai Li, D Christopher Radford, Chelsea D. Landon, Mark Dewhirst, and Ashutosh Chilkoti. “Rational design of "heat seeking" drug loaded polypeptide nanoparticles that thermally target solid tumors.” Nano Lett 14, no. 5 (May 14, 2014): 2890–95. https://doi.org/10.1021/nl5009376.Full Text Link to Item
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Inman, Brant A., Paul R. Stauffer, Oana A. Craciunescu, Paolo F. Maccarini, Mark W. Dewhirst, and Zeljko Vujaskovic. “A pilot clinical trial of intravesical mitomycin-C and external deep pelvic hyperthermia for non-muscle-invasive bladder cancer.” Int J Hyperthermia 30, no. 3 (May 2014): 171–75. https://doi.org/10.3109/02656736.2014.882021.Full Text Link to Item
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Juang, Titania, Paul R. Stauffer, Oana A. Craciunescu, Paolo F. Maccarini, Yu Yuan, Shiva K. Das, Mark W. Dewhirst, Brant A. Inman, and Zeljko Vujaskovic. “Thermal dosimetry characteristics of deep regional heating of non-muscle invasive bladder cancer.” Int J Hyperthermia 30, no. 3 (May 2014): 176–83. https://doi.org/10.3109/02656736.2014.898338.Full Text Link to Item
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Speicher, Paul J., Georgia M. Beasley, Betty Jiang, Michael E. Lidsky, Gregory M. Palmer, Peter M. Scarbrough, Paul J. Mosca, Mark W. Dewhirst, and Douglas S. Tyler. “Hypoxia in melanoma: using optical spectroscopy and EF5 to assess tumor oxygenation before and during regional chemotherapy for melanoma.” Ann Surg Oncol 21, no. 5 (May 2014): 1435–40. https://doi.org/10.1245/s10434-013-3222-0.Full Text Link to Item
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Jones, Lee W., and Mark W. Dewhirst. “Therapeutic properties of aerobic training after a cancer diagnosis: more than a one-trick pony?” J Natl Cancer Inst 106, no. 4 (April 2014): dju042. https://doi.org/10.1093/jnci/dju042.Full Text Link to Item
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Belley, Matthew D., Chu Wang, Giao Nguyen, Rathnayaka Gunasingha, Nelson J. Chao, Benny J. Chen, Mark W. Dewhirst, and Terry T. Yoshizumi. “Toward an organ based dose prescription method for the improved accuracy of murine dose in orthovoltage x-ray irradiators.” Med Phys 41, no. 3 (March 2014): 034101. https://doi.org/10.1118/1.4864237.Full Text Link to Item
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“Corrigendum.” Microcirculation 21, no. 2 (February 2014): 196–196. https://doi.org/10.1111/micc.12118.Full Text
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Frees, Amy E., Narasimhan Rajaram, Samuel S. McCachren, Andrew N. Fontanella, Mark W. Dewhirst, and Nimmi Ramanujam. “Delivery-corrected imaging of fluorescently-labeled glucose reveals distinct metabolic phenotypes in murine breast cancer.” Plos One 9, no. 12 (2014): e115529. https://doi.org/10.1371/journal.pone.0115529.Full Text Link to Item
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Radiloff, Daniel, Yulin Zhao, Alina Boico, Gert Blueschke, Gregory Palmer, Andrew Fontanella, Mark Dewhirst, et al. “Anti-hypotensive treatment and endothelin blockade synergistically antagonize exercise fatigue in rats under simulated high altitude.” Plos One 9, no. 6 (2014): e99309. https://doi.org/10.1371/journal.pone.0099309.Full Text Open Access Copy Link to Item
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Rugo, H. S., T. M. Zagar, S. C. Formenti, Z. Vujaskovic, F. Muggia, B. M. O’Connor, R. J. Myerson, et al. “Abstract P4-15-05: Novel targeted therapy for breast cancer chest wall recurrence: Low temperature liposomal doxorubicin and mild local hyperthermia.” Poster Session Abstracts, December 15, 2013. https://doi.org/10.1158/0008-5472.sabcs13-p4-15-05.Full Text
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Oliveira, Tiago R., Paul R. Stauffer, Chen-Ting Lee, Chelsea D. Landon, Wiguins Etienne, Kathleen A. Ashcraft, Katie L. McNerny, et al. “Magnetic fluid hyperthermia for bladder cancer: a preclinical dosimetry study.” Int J Hyperthermia 29, no. 8 (December 2013): 835–44. https://doi.org/10.3109/02656736.2013.834384.Full Text Link to Item
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Needham, D., and M. W. Dewhirst. “Materials science and engineering of the low temperature sensitive liposome (LTSL): Composition-structure-property relationships that underlie its design and performance.” Rsc Smart Materials 1, no. 1 (November 25, 2013): 33–79.
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Batinic-Haberle, Ines, Artak Tovmasyan, Tin Weitner, Zrinka Rajic, Stephen T. Keir, Ting-Ting Huang, David Leu, et al. “Mechanistic Considerations of the Therapeutic Effects of Mn Porphyrins, Commonly Regarded as SOD Mimics, in Anticancer Therapy: Lessons from Brain and Lymphoma Studies.” Free Radical Biology and Medicine 65 (November 2013): S120–21. https://doi.org/10.1016/j.freeradbiomed.2013.10.691.Full Text
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Fontanella, Andrew N., Thies Schroeder, Daryl W. Hochman, Raymond E. Chen, Gabi Hanna, Michael M. Haglund, Narasimhan Rajaram, et al. “Quantitative mapping of hemodynamics in the lung, brain, and dorsal window chamber-grown tumors using a novel, automated algorithm.” Microcirculation 20, no. 8 (November 2013): 724–35. https://doi.org/10.1111/micc.12072.Full Text Link to Item
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Yuan, Hsiangkuo, Christina L. Hofmann, Jelena Samonina-Kosicka, Hansford Hendargo, Gabi Hanna, Tuan Vo-Dinh, Cassandra L. Fraser, Mark W. Dewhirst, and Gregory M. Palmer. “Abstract B151: Monitoring tumor microenvironment (Hb saturation and oxygenation) in response to plasmonics-assisted photothermal cancer therapy.” Molecular Cancer Therapeutics 12, no. 11_Supplement (November 1, 2013): B151–B151. https://doi.org/10.1158/1535-7163.targ-13-b151.Full Text
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Zhang, Tian, Shiva K. Das, Diane R. Fels, Katherine S. Hansen, Terence Z. Wong, Mark W. Dewhirst, and Gordana Vlahovic. “PET with 62Cu-ATSM and 62Cu-PTSM is a useful imaging tool for hypoxia and perfusion in pulmonary lesions.” Ajr Am J Roentgenol 201, no. 5 (November 2013): W698–706. https://doi.org/10.2214/AJR.12.9698.Full Text Link to Item
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Cao, Yiting, Joseph M. Eble, Ejung Moon, Hong Yuan, Douglas H. Weitzel, Chelsea D. Landon, Charleen Yu-Chih Nien, et al. “Tumor cells upregulate normoxic HIF-1α in response to doxorubicin.” Cancer Res 73, no. 20 (October 15, 2013): 6230–42. https://doi.org/10.1158/0008-5472.CAN-12-1345.Full Text Link to Item
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Dewhirst, Mark W. “Introduction: tumor as an organ.” Semin Radiat Oncol 23, no. 4 (October 2013): 235–36. https://doi.org/10.1016/j.semradonc.2013.05.005.Full Text Link to Item
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Dewhirst, Mark W., and Jen-Tsan Chi. “Understanding the tumor microenvironment and radioresistance by combining functional imaging with global gene expression.” Semin Radiat Oncol 23, no. 4 (October 2013): 296–305. https://doi.org/10.1016/j.semradonc.2013.05.004.Full Text Link to Item
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Repasky, Elizabeth A., Sharon S. Evans, and Mark W. Dewhirst. “Temperature matters! And why it should matter to tumor immunologists.” Cancer Immunol Res 1, no. 4 (October 2013): 210–16. https://doi.org/10.1158/2326-6066.CIR-13-0118.Full Text Link to Item
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Landon, Chelsea D., Sarah E. Benjamin, Kathleen A. Ashcraft, and Mark W. Dewhirst. “A role for the copper transporter Ctr1 in the synergistic interaction between hyperthermia and cisplatin treatment.” Int J Hyperthermia 29, no. 6 (September 2013): 528–38. https://doi.org/10.3109/02656736.2013.790563.Full Text Link to Item
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McDaniel, Jonathan R., Mark W. Dewhirst, and Ashutosh Chilkoti. “Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia.” Int J Hyperthermia 29, no. 6 (September 2013): 501–10. https://doi.org/10.3109/02656736.2013.819999.Full Text Link to Item
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Davis, Ryan M., Benjamin L. Viglianti, Pavel Yarmolenko, Ji-Young Park, Paul Stauffer, David Needham, and Mark W. Dewhirst. “A method to convert MRI images of temperature change into images of absolute temperature in solid tumours.” Int J Hyperthermia 29, no. 6 (September 2013): 569–81. https://doi.org/10.3109/02656736.2013.790091.Full Text Link to Item
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Jones, Lee W., Diane R. Fels, Miranda West, Jason D. Allen, Gloria Broadwater, William T. Barry, Lee G. Wilke, et al. “Modulation of circulating angiogenic factors and tumor biology by aerobic training in breast cancer patients receiving neoadjuvant chemotherapy.” Cancer Prev Res (Phila) 6, no. 9 (September 2013): 925–37. https://doi.org/10.1158/1940-6207.CAPR-12-0416.Full Text Link to Item
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Chitneni, Satish K., Gerald T. Bida, Hong Yuan, Gregory M. Palmer, Michael P. Hay, Thorsten Melcher, William R. Wilson, Michael R. Zalutsky, and Mark W. Dewhirst. “18F-EF5 PET imaging as an early response biomarker for the hypoxia-activated prodrug SN30000 combined with radiation treatment in a non-small cell lung cancer xenograft model.” J Nucl Med 54, no. 8 (August 2013): 1339–46. https://doi.org/10.2967/jnumed.112.116293.Full Text Link to Item
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Rhoon, Gerard C. van, Theodoros Samaras, Pavel S. Yarmolenko, Mark W. Dewhirst, Esra Neufeld, and Niels Kuster. “CEM43°C thermal dose thresholds: a potential guide for magnetic resonance radiofrequency exposure levels?” Eur Radiol 23, no. 8 (August 2013): 2215–27. https://doi.org/10.1007/s00330-013-2825-y.Full Text Link to Item
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Dewhirst, Mark W., Chelsea D. Landon, Christina L. Hofmann, and Paul R. Stauffer. “Novel approaches to treatment of hepatocellular carcinoma and hepatic metastases using thermal ablation and thermosensitive liposomes.” Surg Oncol Clin N Am 22, no. 3 (July 2013): 545–61. https://doi.org/10.1016/j.soc.2013.02.009.Full Text Link to Item
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Bache, S., T. Juang, J. Adamovics, R. Benning, B. Koontz, K. Predmore, M. Dewhirst, and M. Oldham. “WE-E-108-09: An Investigation of the Feasibility of Rodentmorphic 3D Dosimeters for Verification of Precision Micro-Irradiator Treatment.” Med Phys 40, no. 6Part29 (June 2013): 490. https://doi.org/10.1118/1.4815587.Full Text Link to Item
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Kinev, Alexander V., Vrad Levering, Kenneth Young, Francis Ali-Osman, George A. Truskey, Mark W. Dewhirst, and Dora Il’yasova. “Endothelial colony forming cells (ECFCs) as a model for studying effects of low-dose ionizing radiation: growth inhibition by a single dose.” Cancer Invest 31, no. 5 (June 2013): 359–64. https://doi.org/10.3109/07357907.2013.789903.Full Text Link to Item
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Oldham, M., A. Thomas, and M. Dewhirst. “MO-D-141-09: An Investigation of the Feasibility of Volumetric Imaging of Fluorescent Bio-Markers Using Optical-ECT.” Med Phys 40, no. 6Part24 (June 2013): 401. https://doi.org/10.1118/1.4815256.Full Text Link to Item
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Yu, B., A. Shah, B. Wang, N. Rajaram, Q. Wang, N. Ramanujam, G. M. Palmer, and M. W. Dewhirst. “Monitoring of cycling hypoxia and angiogenesis in FaDu head and neck tumors using a side-firing sensor.” Progress in Biomedical Optics and Imaging Proceedings of Spie 8578 (May 27, 2013). https://doi.org/10.1117/12.2002837.Full Text
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Kurokawa, Manabu, Jiyeon Kim, Joseph Geradts, Kenkyo Matsuura, Liu Liu, Xu Ran, Wenle Xia, et al. “A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.” Sci Signal 6, no. 274 (May 7, 2013): ra32. https://doi.org/10.1126/scisignal.2003741.Full Text Open Access Copy Link to Item
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Klink, Joseph C., Alok K. Tewari, Elizabeth M. Masko, Jodi Antonelli, Phillip G. Febbo, Pinchas Cohen, Mark W. Dewhirst, Salvatore V. Pizzo, and Stephen J. Freedland. “Resveratrol worsens survival in SCID mice with prostate cancer xenografts in a cell-line specific manner, through paradoxical effects on oncogenic pathways.” Prostate 73, no. 7 (May 2013): 754–62. https://doi.org/10.1002/pros.22619.Full Text Link to Item
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Inman, Brant A., Wiguins Etienne, Rainier Rubin, Richmond A. Owusu, Tiago R. Oliveira, Dario B. Rodriques, Paolo F. Maccarini, Paul R. Stauffer, Alireza Mashal, and Mark W. Dewhirst. “The impact of temperature and urinary constituents on urine viscosity and its relevance to bladder hyperthermia treatment.” Int J Hyperthermia 29, no. 3 (May 2013): 206–10. https://doi.org/10.3109/02656736.2013.775355.Full Text Link to Item
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Azrad, Maria, Robin T. Vollmer, John Madden, Mark Dewhirst, Thomas J. Polascik, Denise C. Snyder, Mack T. Ruffin, Judd W. Moul, Dean E. Brenner, and Wendy Demark-Wahnefried. “Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer.” J Med Food 16, no. 4 (April 2013): 357–60. https://doi.org/10.1089/jmf.2012.0159.Full Text Link to Item
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Caso, Jorge, Elizabeth M. Masko, Jean A Thomas Ii, Susan H. Poulton, Mark Dewhirst, Salvatore V. Pizzo, and Stephen J. Freedland. “The effect of carbohydrate restriction on prostate cancer tumor growth in a castrate mouse xenograft model.” Prostate 73, no. 5 (April 2013): 449–54. https://doi.org/10.1002/pros.22586.Full Text Link to Item
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Betof, Allison S., Mark W. Dewhirst, and Lee W. Jones. “Effects and potential mechanisms of exercise training on cancer progression: a translational perspective.” Brain Behav Immun 30 Suppl (March 2013): S75–87. https://doi.org/10.1016/j.bbi.2012.05.001.Full Text Link to Item
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Zhong, Jim, Narasimhan Rajaram, David M. Brizel, Amy E. Frees, Nirmala Ramanujam, Ines Batinic-Haberle, and Mark W. Dewhirst. “Radiation induces aerobic glycolysis through reactive oxygen species.” Radiother Oncol 106, no. 3 (March 2013): 390–96. https://doi.org/10.1016/j.radonc.2013.02.013.Full Text Link to Item
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Hanna, Gabi, Andrew Fontanella, Gregory Palmer, Siqing Shan, Daniel R. Radiloff, Yulin Zhao, David Irwin, et al. “Automated measurement of blood flow velocity and direction and hemoglobin oxygen saturation in the rat lung using intravital microscopy.” Am J Physiol Lung Cell Mol Physiol 304, no. 2 (January 15, 2013): L86–91. https://doi.org/10.1152/ajplung.00178.2012.Full Text Link to Item
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Kennedy, Kelly M., Peter M. Scarbrough, Anthony Ribeiro, Rachel Richardson, Hong Yuan, Pierre Sonveaux, Chelsea D. Landon, et al. “Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.” Plos One 8, no. 9 (2013): e75154. https://doi.org/10.1371/journal.pone.0075154.Full Text Link to Item
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Rajaram, Narasimhan, Amy E. Frees, Andrew N. Fontanella, Jim Zhong, Katherine Hansen, Mark W. Dewhirst, and Nirmala Ramanujam. “Delivery rate affects uptake of a fluorescent glucose analog in murine metastatic breast cancer.” Plos One 8, no. 10 (2013): e76524. https://doi.org/10.1371/journal.pone.0076524.Full Text Link to Item
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Secomb, Timothy W., Jonathan P. Alberding, Richard Hsu, Mark W. Dewhirst, and Axel R. Pries. “Angiogenesis: an adaptive dynamic biological patterning problem.” Plos Comput Biol 9, no. 3 (2013): e1002983. https://doi.org/10.1371/journal.pcbi.1002983.Full Text Link to Item
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Terman, David S., Benjamin L. Viglianti, Rahima Zennadi, Diane Fels, Richard J. Boruta, Hong Yuan, Mathew R. Dreher, et al. “Sickle erythrocytes target cytotoxics to hypoxic tumor microvessels and potentiate a tumoricidal response.” Plos One 8, no. 1 (2013): e52543. https://doi.org/10.1371/journal.pone.0052543.Full Text Open Access Copy Link to Item
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Beasley, Georgia M., Ketan Sharma, Joyce Wong, Mike Miller, Ryan S. Turley, Michael Lidsky, Melanie Masoud, et al. “A multi-institution experience comparing the clinical and physiologic differences between upper extremity and lower extremity melphalan-based isolated limb infusion.” Cancer 118, no. 24 (December 15, 2012): 6136–43. https://doi.org/10.1002/cncr.27676.Full Text Link to Item
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Manzoor, Ashley A., Lars H. Lindner, Chelsea D. Landon, Ji-Young Park, Andrew J. Simnick, Matthew R. Dreher, Shiva Das, et al. “Overcoming limitations in nanoparticle drug delivery: triggered, intravascular release to improve drug penetration into tumors.” Cancer Res 72, no. 21 (November 1, 2012): 5566–75. https://doi.org/10.1158/0008-5472.CAN-12-1683.Full Text Link to Item
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Yan, Bin, Ruoyun Ouyang, Chenghui Huang, Franklin Liu, Daniel Neill, Chuanyuan Li, and Mark Dewhirst. “Heat induces gene amplification in cancer cells.” Biochem Biophys Res Commun 427, no. 3 (October 26, 2012): 473–77. https://doi.org/10.1016/j.bbrc.2012.09.011.Full Text Link to Item
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Horton, Janet K., Diane R. Fels, Hsiu-Ni Kung, Yingchun Zhou, Kathleen Ashcraft, Mark W. Dewhirst, and Jen-Tsan Ashley Chi. “Differential Activation of Cell Death Pathways After Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines.” Journal of Womens Health 21, no. 10 (October 1, 2012): 992–992.Link to Item
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Kim, Howard S., Elizabeth M. Masko, Susan L. Poulton, Kelly M. Kennedy, Salvatore V. Pizzo, Mark W. Dewhirst, and Stephen J. Freedland. “Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer.” Bju Int 110, no. 7 (October 2012): 1062–69. https://doi.org/10.1111/j.1464-410X.2012.10971.x.Full Text Link to Item
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Chitneni, Satish K., Gerald T. Bida, Mark W. Dewhirst, and Michael R. Zalutsky. “A simplified synthesis of the hypoxia imaging agent 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-[(18)F]pentafluoropropyl)-acetamide ([18F]EF5).” Nucl Med Biol 39, no. 7 (October 2012): 1012–18. https://doi.org/10.1016/j.nucmedbio.2012.05.006.Full Text Link to Item
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Jones, Lee W., Jodi Antonelli, Elizabeth M. Masko, Gloria Broadwater, Christopher D. Lascola, Diane Fels, Mark W. Dewhirst, et al. “Exercise modulation of the host-tumor interaction in an orthotopic model of murine prostate cancer.” J Appl Physiol (1985) 113, no. 2 (July 2012): 263–72. https://doi.org/10.1152/japplphysiol.01575.2011.Full Text Link to Item
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Turley, Ryan S., Andrew N. Fontanella, James C. Padussis, Hiroaki Toshimitsu, Yoshihiro Tokuhisa, Eugenia H. Cho, Gabi Hanna, et al. “Bevacizumab-induced alterations in vascular permeability and drug delivery: a novel approach to augment regional chemotherapy for in-transit melanoma.” Clin Cancer Res 18, no. 12 (June 15, 2012): 3328–39. https://doi.org/10.1158/1078-0432.CCR-11-3000.Full Text Link to Item
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Wang, C., M. Dewhirst, X. Jiang, Z. Qian, S. Boon, and T. Yoshizumi. “SU-E-I-07: Proposal for a Novel Algorithm of Effective Dose Evaluation for Medical Radiation Exposure.” Med Phys 39, no. 6Part4 (June 2012): 3626. https://doi.org/10.1118/1.4734721.Full Text Link to Item
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McDaniel, Jonathan R., Sarah R. Macewan, Mark Dewhirst, and Ashutosh Chilkoti. “Doxorubicin-conjugated chimeric polypeptide nanoparticles that respond to mild hyperthermia.” J Control Release 159, no. 3 (May 10, 2012): 362–67. https://doi.org/10.1016/j.jconrel.2012.02.030.Full Text Link to Item
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Masko, Elizabeth M., Keith R. Solomon, Nikolaos A. Valilis, Alexis R. Gaines, Michael J. Muehlbauer, Christopher B. Newgard, Mark W. Dewhirst, Salvatore V. Pizzo, and Stephen J. Freedland. “Abstract 3220: The effects of cholesterol treatment drugs alone and in combination on prostate tumor xenograft growth.” Molecular and Cellular Biology, April 15, 2012. https://doi.org/10.1158/1538-7445.am2012-3220.Full Text
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Yuan, Yu, Cory Wyatt, Paolo Maccarini, Paul Stauffer, Oana Craciunescu, James Macfall, Mark Dewhirst, and Shiva K. Das. “A heterogeneous human tissue mimicking phantom for RF heating and MRI thermal monitoring verification.” Phys Med Biol 57, no. 7 (April 7, 2012): 2021–37. https://doi.org/10.1088/0031-9155/57/7/2021.Full Text Link to Item
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Humm, John L., Mark W. Dewhirst, and Zaver M. Bhujwalla. “Introduction to the special issue on molecular imaging in radiation biology.” Radiat Res 177, no. 4 (April 2012): 329–30. https://doi.org/10.1667/rr2959.1.Full Text Link to Item
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Palmer, Gregory M., Karthik Vishwanath, and Mark W. Dewhirst. “Application of optical imaging and spectroscopy to radiation biology.” Radiat Res 177, no. 4 (April 2012): 365–75. https://doi.org/10.1667/rr2531.1.Full Text Link to Item
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Palmer, G. M., Z. Tiran, Z. Zhou, M. E. Capozzi, W. Park, C. Coletta, A. Pyriochou, et al. “A novel angiopoietin-derived peptide displays anti-angiogenic activity and inhibits tumour-induced and retinal neovascularization.” Br J Pharmacol 165, no. 6 (March 2012): 1891–1903. https://doi.org/10.1111/j.1476-5381.2011.01677.x.Full Text Link to Item
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Yuan, Yu, Kung-Shan Cheng, Oana I. Craciunescu, Paul R. Stauffer, Paolo F. Maccarini, Kavitha Arunachalam, Zeljko Vujaskovic, Mark W. Dewhirst, and Shiva K. Das. “Utility of treatment planning for thermochemotherapy treatment of nonmuscle invasive bladder carcinoma.” Med Phys 39, no. 3 (March 2012): 1170–81. https://doi.org/10.1118/1.3679839.Full Text Link to Item
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Betof, A. S., Z. N. Rabbani, M. E. Hardee, S. J. Kim, G. Broadwater, R. C. Bentley, S. A. Snyder, et al. “Carbonic anhydrase IX is a predictive marker of doxorubicin resistance in early-stage breast cancer independent of HER2 and TOP2A amplification.” Br J Cancer 106, no. 5 (February 28, 2012): 916–22. https://doi.org/10.1038/bjc.2012.32.Full Text Link to Item
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Aird, Katherine M., Jennifer L. Allensworth, Ines Batinic-Haberle, H Kim Lyerly, Mark W. Dewhirst, and Gayathri R. Devi. “ErbB1/2 tyrosine kinase inhibitor mediates oxidative stress-induced apoptosis in inflammatory breast cancer cells.” Breast Cancer Res Treat 132, no. 1 (February 2012): 109–19. https://doi.org/10.1007/s10549-011-1568-1.Full Text Link to Item
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Shenoy, S. K., S. Han, Y. L. Zhao, M. R. Hara, T. Oliver, Y. Cao, and M. W. Dewhirst. “β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression.” Oncogene 31, no. 3 (January 19, 2012): 282–92. https://doi.org/10.1038/onc.2011.238.Full Text Link to Item
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Cao, X., J. Geradts, M. W. Dewhirst, and H. -. W. Lo. “Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.” Oncogene 31, no. 1 (January 5, 2012): 104–15. https://doi.org/10.1038/onc.2011.219.Full Text Link to Item
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Batinic-Haberle, I., I. Spasojevic, H. M. Tse, A. Tovmasyan, Z. Rajic, D. K. S. Clair, Z. Vujaskovic, M. W. Dewhirst, and J. D. Piganelli. “Erratum: Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities (Amino Acids DOI: 10.1007/s00726-010-0603-6).” Amino Acids 42, no. 1 (January 1, 2012): 115–16. https://doi.org/10.1007/s00726-010-0821-y.Full Text
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Batinic-Haberle, Ines, Ivan Spasojevic, Hubert M. Tse, Artak Tovmasyan, Zrinka Rajic, Daret K. St Clair, Zeljko Vujaskovic, Mark W. Dewhirst, and Jon D. Piganelli. “Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.” Amino Acids 42, no. 1 (January 2012): 95–113. https://doi.org/10.1007/s00726-010-0603-6.Full Text Link to Item
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Salahi, Sara, Paolo F. Maccarini, Dario B. Rodrigues, Wiguins Etienne, Chelsea D. Landon, Brant A. Inman, Mark W. Dewhirst, and Paul R. Stauffer. “Miniature microwave applicator for murine bladder hyperthermia studies.” Int J Hyperthermia 28, no. 5 (2012): 456–65. https://doi.org/10.3109/02656736.2012.677931.Full Text Link to Item
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Secomb, Timothy W., Mark W. Dewhirst, and Axel R. Pries. “Structural adaptation of normal and tumour vascular networks.” Basic Clin Pharmacol Toxicol 110, no. 1 (January 2012): 63–69. https://doi.org/10.1111/j.1742-7843.2011.00815.x.Full Text Link to Item
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Thrall, Donald E., Paolo Maccarini, Paul Stauffer, James Macfall, Marlene Hauck, Stacey Snyder, Beth Case, et al. “Thermal dose fractionation affects tumour physiological response.” Int J Hyperthermia 28, no. 5 (2012): 431–40. https://doi.org/10.3109/02656736.2012.689087.Full Text Link to Item
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Palmer, Gregory M., Andrew N. Fontanella, Siqing Shan, and Mark W. Dewhirst. “High-resolution in vivo imaging of fluorescent proteins using window chamber models.” Methods Mol Biol 872 (2012): 31–50. https://doi.org/10.1007/978-1-61779-797-2_3.Full Text Link to Item
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Sonveaux, Pierre, Tamara Copetti, Christophe J. De Saedeleer, Frédérique Végran, Julien Verrax, Kelly M. Kennedy, Eui Jung Moon, et al. “Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis.” Plos One 7, no. 3 (2012): e33418. https://doi.org/10.1371/journal.pone.0033418.Full Text Link to Item
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Ye, Xiaodong, Diane Fels, Artak Tovmasyan, Katherine M. Aird, Casey Dedeugd, Jennifer L. Allensworth, Ivan Kos, et al. “Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate.” Free Radic Res 45, no. 11–12 (November 2011): 1289–1306. https://doi.org/10.3109/10715762.2011.616199.Full Text Link to Item
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Grant, Gerald A., Christy Wilson, Sara Salami, Paolo Macaroni, Shuqin Li, Ji-Young Park, David Needham, Darell Bigner, and Mark Dewhirst. “PRECLINICAL USE OF MILD HYPERTHERMIA TO ENHANCE DRUG DELIVERY TO BRAIN TUMORS.” Neuro Oncology 13 (November 1, 2011): 111–111.Link to Item
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Simnick, Andrew J., Miriam Amiram, Wenge Liu, Gabi Hanna, Mark W. Dewhirst, Christopher D. Kontos, and Ashutosh Chilkoti. “In vivo tumor targeting by a NGR-decorated micelle of a recombinant diblock copolypeptide.” J Control Release 155, no. 2 (October 30, 2011): 144–51. https://doi.org/10.1016/j.jconrel.2011.06.044.Full Text Link to Item
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Fisher, Daniel T., Qing Chen, Joseph J. Skitzki, Jason B. Muhitch, Lei Zhou, Michelle M. Appenheimer, Trupti D. Vardam, et al. “IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells.” J Clin Invest 121, no. 10 (October 2011): 3846–59. https://doi.org/10.1172/JCI44952.Full Text Link to Item
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Heymach, John V., Terry J. Shackleford, Hai T. Tran, Suk-Young Yoo, Kim-Anh Do, Melanie Wergin, Pierre Saintigny, et al. “Effect of low-fat diets on plasma levels of NF-κB-regulated inflammatory cytokines and angiogenic factors in men with prostate cancer.” Cancer Prev Res (Phila) 4, no. 10 (October 2011): 1590–98. https://doi.org/10.1158/1940-6207.CAPR-10-0136.Full Text Link to Item
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Horton, J. K., D. R. Fels, J. A. Chi, H. Kung, J. P. Kirkpatrick, and M. Dewhirst. “Protein Pathway Activation after Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines.” International Journal of Radiation Oncology*Biology*Physics 81, no. 2 (October 2011): S160–61. https://doi.org/10.1016/j.ijrobp.2011.06.1658.Full Text
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Horton, Janet K., Diane R. Fels, Hsiu-Ni Kung, Mark W. Dewhirst, and Jen-Tsan Ashley Chi. “Gene Expression Response of Luminal and Basal Breast Cancer Cell Lines to Ionizing Radiation.” Journal of Womens Health 20, no. 10 (October 1, 2011): 1404–5.Link to Item
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Yan, B., D. M. Neill, T. Liu, and M. W. Dewhirst. “42 and 44°C Hyperthermia Induces Gene Amplification in Colorectal Cancer HCT116 Cells.” International Journal of Radiation Oncology*Biology*Physics 81, no. 2 (October 2011): S701–S701. https://doi.org/10.1016/j.ijrobp.2011.06.1340.Full Text
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Batinic-Haberle, Ines, Zrinka Rajic, Artak Tovmasyan, Julio S. Reboucas, Xiaodong Ye, Kam W. Leong, Mark W. Dewhirst, Zeljko Vujaskovic, Ludmil Benov, and Ivan Spasojevic. “Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics.” Free Radic Biol Med 51, no. 5 (September 1, 2011): 1035–53. https://doi.org/10.1016/j.freeradbiomed.2011.04.046.Full Text Link to Item
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Palmer, Gregory M., Andrew N. Fontanella, Siqing Shan, Gabi Hanna, Guoqing Zhang, Cassandra L. Fraser, and Mark W. Dewhirst. “In vivo optical molecular imaging and analysis in mice using dorsal window chamber models applied to hypoxia, vasculature and fluorescent reporters.” Nat Protoc 6, no. 9 (August 18, 2011): 1355–66. https://doi.org/10.1038/nprot.2011.349.Full Text Link to Item
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Gatza, Michael L., Hsiu-Ni Kung, Kimberly L. Blackwell, Mark W. Dewhirst, Jeffrey R. Marks, and Jen-Tsan Chi. “Analysis of tumor environmental response and oncogenic pathway activation identifies distinct basal and luminal features in HER2-related breast tumor subtypes.” Breast Cancer Res 13, no. 3 (June 7, 2011): R62. https://doi.org/10.1186/bcr2899.Full Text Link to Item
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Zhang, Tian, Diane R. Fels, Katherine S. Hansen, Shiva K. Das, Terence Z. Wong, Mark W. Dewhirst, and Gordana Vlahovic. “62CUATSM AND 62CUPTSM PET IS A USEFUL IMAGING TOOL FOR HYPOXIA AND PERFUSION IN LUNG CANCER.” Journal of Thoracic Oncology 6, no. 6 (June 1, 2011): S919–20.Link to Item
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Cao, Xinyu, Mark Dewhirst, Francis Ali-Osman, and Hui-Wen Lo. “Abstract 2337: Defining significance of the novel tGLI1 transcription factor in cancer growth and progression.” Tumor Biology, April 15, 2011. https://doi.org/10.1158/1538-7445.am2011-2337.Full Text
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Chi, Jen-Tsan, Donald E. Thrall, Chen Jiang, Stacey Snyder, Diane Fels, Chelsea Landon, Linda McCall, et al. “Comparison of genomics and functional imaging from canine sarcomas treated with thermoradiotherapy predicts therapeutic response and identifies combination therapeutics.” Clin Cancer Res 17, no. 8 (April 15, 2011): 2549–60. https://doi.org/10.1158/1078-0432.CCR-10-2583.Full Text Link to Item
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Chitneni, Satish K., Gerald T. Bida, Michael P. Hay, Michael R. Zalutsky, Thorsten Melcher, William R. Wilson, and Mark W. Dewhirst. “Abstract 5306:18F-EF5 microPET imaging of treatment response from a novel, hypoxia-selective cytotoxin SN30000 in a human lung cancer xenograft model.” Tumor Biology, April 15, 2011. https://doi.org/10.1158/1538-7445.am2011-5306.Full Text
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Spasojevic, Ivan, Ivan Kos, Ludmil T. Benov, Zrinka Rajic, Diane Fels, Casey Dedeugd, Xiaodong Ye, et al. “Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site.” Free Radic Res 45, no. 2 (February 2011): 188–200. https://doi.org/10.3109/10715762.2010.522575.Full Text Link to Item
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Chitneni, Satish K., Gregory M. Palmer, Michael R. Zalutsky, and Mark W. Dewhirst. “Molecular imaging of hypoxia.” J Nucl Med 52, no. 2 (February 2011): 165–68. https://doi.org/10.2967/jnumed.110.075663.Full Text Link to Item
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Keir, Stephen T., Mark W. Dewhirst, John P. Kirkpatrick, Darell D. Bigner, and Ines Batinic-Haberle. “Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors.” Anticancer Agents Med Chem 11, no. 2 (February 2011): 202–12. https://doi.org/10.2174/187152011795255957.Full Text Link to Item
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Il’yasova, Dora, Kelly Kennedy, Ivan Spasojevic, Frances Wang, Adviye A. Tolun, Karel Base, Sarah P. Young, et al. “Individual responses to chemotherapy-induced oxidative stress.” Breast Cancer Res Treat 125, no. 2 (January 2011): 583–89. https://doi.org/10.1007/s10549-010-1158-7.Full Text Link to Item
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Negussie, Ayele H., Pavel S. Yarmolenko, Ari Partanen, Ashish Ranjan, Genevieve Jacobs, David Woods, Henry Bryant, et al. “Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound.” Int J Hyperthermia 27, no. 2 (2011): 140–55. https://doi.org/10.3109/02656736.2010.528140.Full Text Link to Item
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Yarmolenko, Pavel S., Eui Jung Moon, Chelsea Landon, Ashley Manzoor, Daryl W. Hochman, Benjamin L. Viglianti, and Mark W. Dewhirst. “Thresholds for thermal damage to normal tissues: an update.” Int J Hyperthermia 27, no. 4 (2011): 320–43. https://doi.org/10.3109/02656736.2010.534527.Full Text Link to Item
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Landon, Chelsea D., Ji-Young Park, David Needham, and Mark W. Dewhirst. “Nanoscale Drug Delivery and Hyperthermia: The Materials Design and Preclinical and Clinical Testing of Low Temperature-Sensitive Liposomes Used in Combination with Mild Hyperthermia in the Treatment of Local Cancer.” Open Nanomed J 3 (January 1, 2011): 38–64. https://doi.org/10.2174/1875933501103010038.Full Text Link to Item
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Zagar, Timothy M., Kristin A. Higgins, Edward F. Miles, Zeljko Vujaskovic, Mark W. Dewhirst, Robert W. Clough, Leonard R. Prosnitz, and Ellen L. Jones. “Durable palliation of breast cancer chest wall recurrence with radiation therapy, hyperthermia, and chemotherapy.” Radiother Oncol 97, no. 3 (December 2010): 535–40. https://doi.org/10.1016/j.radonc.2010.10.020.Full Text Link to Item
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Moon, Eui Jung, Pierre Sonveaux, Paolo E. Porporato, Pierre Danhier, Bernard Gallez, Ines Batinic-Haberle, Yu-Chih Nien, Thies Schroeder, and Mark W. Dewhirst. “NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment.” Proc Natl Acad Sci U S A 107, no. 47 (November 23, 2010): 20477–82. https://doi.org/10.1073/pnas.1006646107.Full Text Link to Item
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Palmer, Gregory M., Andrew N. Fontanella, Guoqing Zhang, Gabi Hanna, Cassandra L. Fraser, and Mark W. Dewhirst. “Optical imaging of tumor hypoxia dynamics.” J Biomed Opt 15, no. 6 (November 2010): 066021. https://doi.org/10.1117/1.3523363.Full Text Link to Item
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Kersey, Farrell R., Guoqing Zhang, Gregory M. Palmer, Mark W. Dewhirst, and Cassandra L. Fraser. “Stereocomplexed poly(lactic acid)-poly(ethylene glycol) nanoparticles with dual-emissive boron dyes for tumor accumulation.” Acs Nano 4, no. 9 (September 28, 2010): 4989–96. https://doi.org/10.1021/nn901873t.Full Text Open Access Copy Link to Item
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Brady, Samuel L., Rathnayaka Gunasingha, Terry T. Yoshizumi, Calvin R. Howell, Alexander S. Crowell, Brent Fallin, Anton P. Tonchev, and Mark W. Dewhirst. “A feasibility study using radiochromic films for fast neutron 2D passive dosimetry.” Phys Med Biol 55, no. 17 (September 7, 2010): 4977–92. https://doi.org/10.1088/0031-9155/55/17/007.Full Text Link to Item
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Masko, Elizabeth M., Jean A. Thomas, Jodi A. Antonelli, Jessica C. Lloyd, Tameika E. Phillips, Susan H. Poulton, Mark W. Dewhirst, Salvatore V. Pizzo, and Stephen J. Freedland. “Low-carbohydrate diets and prostate cancer: how low is "low enough"?” Cancer Prev Res (Phila) 3, no. 9 (September 2010): 1124–31. https://doi.org/10.1158/1940-6207.CAPR-10-0071.Full Text Link to Item
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Betof, A. S., and M. W. Dewhirst. “Establishing the Tumor Microenvironment,” August 31, 2010, 7–33. https://doi.org/10.1002/9780470669891.ch2.Full Text
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Pries, Axel R., Michael Höpfner, Ferdinand le Noble, Mark W. Dewhirst, and Timothy W. Secomb. “The shunt problem: control of functional shunting in normal and tumour vasculature.” Nat Rev Cancer 10, no. 8 (August 2010): 587–93. https://doi.org/10.1038/nrc2895.Full Text Link to Item
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Thomas, Andrew, James Bowsher, Justin Roper, Tim Oliver, Mark Dewhirst, and Mark Oldham. “A comprehensive method for optical-emission computed tomography.” Phys Med Biol 55, no. 14 (July 21, 2010): 3947–57. https://doi.org/10.1088/0031-9155/55/14/001.Full Text Link to Item
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Tei, Lorenzo, Galit Mazooz, Yael Shellef, Reut Avni, Katrien Vandoorne, Alessandro Barge, Vyacheslav Kalchenko, et al. “Novel MRI and fluorescent probes responsive to the Factor XIII transglutaminase activity.” Contrast Media Mol Imaging 5, no. 4 (July 2010): 213–22. https://doi.org/10.1002/cmmi.392.Full Text Link to Item
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Jenista, Elizabeth R., Gigi Galiana, Rosa T. Branca, Pavel S. Yarmolenko, Ashley M. Stokes, Mark W. Dewhirst, and Warren S. Warren. “Application of mixed spin iMQCs for temperature and chemical-selective imaging.” J Magn Reson 204, no. 2 (June 2010): 208–18. https://doi.org/10.1016/j.jmr.2010.02.021.Full Text Link to Item
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Tailor, Tina D., Gabi Hanna, Pavel S. Yarmolenko, Matthew R. Dreher, Allison S. Betof, Andrew B. Nixon, Ivan Spasojevic, and Mark W. Dewhirst. “Effect of pazopanib on tumor microenvironment and liposome delivery.” Mol Cancer Ther 9, no. 6 (June 2010): 1798–1808. https://doi.org/10.1158/1535-7163.MCT-09-0856.Full Text Link to Item
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Jones, L. W., B. L. Viglianti, J. A. Tashjian, S. M. Kothadia, S. T. Keir, S. J. Freedland, M. Q. Potter, et al. “Erratum: Effect of aerobic exercise on tumor physiology in an animal model of human breast cancer (Journal of Applied Physiology (2010) 108: (343-348) DOI: 10.1152/japplphysiol.00424.2009).” Journal of Applied Physiology 108, no. 4 (April 1, 2010): 1021. https://doi.org/10.1152/japplphysiol.zdg-9024-corr.2010.Full Text
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Secomb, Timothy W., Jonathan P. Alberding, Mark W. Dewhirst, and Axel R. Pries. “Theoretical simulation of angiogenesis and structural adaptation in microvascular networks.” Faseb Journal 24 (April 2010).Link to Item
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Palmer, Gregory M., Richard J. Boruta, Benjamin L. Viglianti, Lan Lan, Ivan Spasojevic, and Mark W. Dewhirst. “Non-invasive monitoring of intra-tumor drug concentration and therapeutic response using optical spectroscopy.” J Control Release 142, no. 3 (March 19, 2010): 457–64. https://doi.org/10.1016/j.jconrel.2009.10.034.Full Text Link to Item
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Cheng, Kung-Shan, Mark W. Dewhirst, Paul F. Stauffer, and Shiva Das. “Mathematical formulation and analysis of the nonlinear system reconstruction of the online image-guided adaptive control of hyperthermia.” Med Phys 37, no. 3 (March 2010): 980–94. https://doi.org/10.1118/1.3298005.Full Text Link to Item
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Cheng, Kung-Shan, Mark W. Dewhirst, Paul R. Stauffer, and Shiva Das. “Effective learning strategies for real-time image-guided adaptive control of multiple-source hyperthermia applicators.” Med Phys 37, no. 3 (March 2010): 1285–97. https://doi.org/10.1118/1.3302829.Full Text Link to Item
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Kim, Seok Jin, Zahid N. Rabbani, Fan Dong, Robin T. Vollmer, Ernst-Gilbert Schreiber, Mark W. Dewhirst, Zeljko Vujaskovic, and Michael J. Kelley. “Phosphorylated epidermal growth factor receptor and cyclooxygenase-2 expression in localized non-small cell lung cancer.” Med Oncol 27, no. 1 (March 2010): 91–97. https://doi.org/10.1007/s12032-009-9178-z.Full Text Link to Item
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Robinson, Timothy J., Michaela A. Dinan, Mark Dewhirst, Mariano A. Garcia-Blanco, and James L. Pearson. “SplicerAV: a tool for mining microarray expression data for changes in RNA processing.” Bmc Bioinformatics 11 (February 25, 2010): 108. https://doi.org/10.1186/1471-2105-11-108.Full Text Open Access Copy Link to Item
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Jones, Lee W., Benjamin L. Viglianti, Jessica A. Tashjian, Sejal M. Kothadia, Stephen T. Keir, Stephen J. Freedland, Michael Q. Potter, et al. “Effect of aerobic exercise on tumor physiology in an animal model of human breast cancer.” J Appl Physiol (1985) 108, no. 2 (February 2010): 343–48. https://doi.org/10.1152/japplphysiol.00424.2009.Full Text Link to Item
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Dewhirst, Mark. “Why Would Hyperthermia Work?” Journal of the National Cancer Institute 102, no. 2 (January 20, 2010): 80–80.Link to Item
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Kennedy, Kelly M., and Mark W. Dewhirst. “Tumor metabolism of lactate: the influence and therapeutic potential for MCT and CD147 regulation.” Future Oncol 6, no. 1 (January 2010): 127–48. https://doi.org/10.2217/fon.09.145.Full Text Link to Item
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Skala, Melissa C., Andrew Fontanella, Lan Lan, Joseph A. Izatt, and Mark W. Dewhirst. “Longitudinal optical imaging of tumor metabolism and hemodynamics.” J Biomed Opt 15, no. 1 (January 2010): 011112. https://doi.org/10.1117/1.3285584.Full Text Link to Item
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Craciunescu, Oana I., Donald E. Thrall, Zeljko Vujaskovic, and Mark W. Dewhirst. “Magnetic resonance imaging: a potential tool in assessing the addition of hyperthermia to neoadjuvant therapy in patients with locally advanced breast cancer.” Int J Hyperthermia 26, no. 7 (2010): 625–37. https://doi.org/10.3109/02656736.2010.499526.Full Text Link to Item
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Dewhirst, Mark W., Donald E. Thrall, Gregory Palmer, Thies Schroeder, Zeljko Vujaskovic, H. Cecil Charles, James Macfall, and Terence Wong. “Utility of functional imaging in prediction or assessment of treatment response and prognosis following thermotherapy.” Int J Hyperthermia 26, no. 3 (2010): 283–93. https://doi.org/10.3109/02656730903286214.Full Text Link to Item
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Vujaskovic, Zeljko, Dong W. Kim, Ellen Jones, Lan Lan, Linda McCall, Mark W. Dewhirst, Oana Craciunescu, et al. “A phase I/II study of neoadjuvant liposomal doxorubicin, paclitaxel, and hyperthermia in locally advanced breast cancer.” Int J Hyperthermia 26, no. 5 (2010): 514–21. https://doi.org/10.3109/02656731003639364.Full Text Link to Item
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Yarmolenko, Pavel S., Yulin Zhao, Chelsea Landon, Ivan Spasojevic, Fan Yuan, David Needham, Benjamin L. Viglianti, and Mark W. Dewhirst. “Comparative effects of thermosensitive doxorubicin-containing liposomes and hyperthermia in human and murine tumours.” Int J Hyperthermia 26, no. 5 (2010): 485–98. https://doi.org/10.3109/02656731003789284.Full Text Link to Item
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Zagar, Timothy M., James R. Oleson, Zeljko Vujaskovic, Mark W. Dewhirst, Oana I. Craciunescu, Kimberly L. Blackwell, Leonard R. Prosnitz, and Ellen L. Jones. “Hyperthermia for locally advanced breast cancer.” Int J Hyperthermia 26, no. 7 (2010): 618–24. https://doi.org/10.3109/02656736.2010.501051.Full Text Link to Item
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Zagar, Timothy M., James R. Oleson, Zeljko Vujaskovic, Mark W. Dewhirst, Oana I. Craciunescu, Kimberly L. Blackwell, Leonard R. Prosnitz, and Ellen L. Jones. “Hyperthermia combined with radiation therapy for superficial breast cancer and chest wall recurrence: a review of the randomised data.” Int J Hyperthermia 26, no. 7 (2010): 612–17. https://doi.org/10.3109/02656736.2010.487194.Full Text Link to Item
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Dewey, W. C., C. J. Diederich, and M. W. Dewhirst. “Erratum: Arrhenius relationships from the molecule and cell to the clinic (International Journal of Hyperthermia (2009) 25 (21-24)).” International Journal of Hyperthermia 25, no. 3 (December 3, 2009): 248. https://doi.org/10.1080/02656730902841118.Full Text
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Dewhirst, Mark W. “Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress.” Radiat Res 172, no. 6 (December 2009): 653–65. https://doi.org/10.1667/RR1926.1.Full Text Link to Item
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Skala, M., A. Fontanella, H. Hendargo, M. Dewhirst, and J. Izatt. “Combined hyperspectral and optical coherence tomography microscope for non-invasive hemodynamic imaging.” Optics Infobase Conference Papers, December 1, 2009.
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Craciunescu, Oana I., Paul R. Stauffer, Brian J. Soher, Cory R. Wyatt, Omar Arabe, Paolo Maccarini, Shiva K. Das, et al. “Accuracy of real time noninvasive temperature measurements using magnetic resonance thermal imaging in patients treated for high grade extremity soft tissue sarcomas.” Med Phys 36, no. 11 (November 2009): 4848–58. https://doi.org/10.1118/1.3227506.Full Text Link to Item
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Yan, Bin, Huili Wang, Donghua Xie, Nobuko Wakamatsu, Mitchell S. Anscher, Mark W. Dewhirst, Ron E. J. Mitchel, Benny J. Chen, and Chuan-Yuan Li. “Increased skin carcinogenesis in caspase-activated DNase knockout mice.” Carcinogenesis 30, no. 10 (October 2009): 1776–80. https://doi.org/10.1093/carcin/bgp146.Full Text Link to Item
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Rabbani, Zahid N., Ivan Spasojevic, Xiuwu Zhang, Benjamin J. Moeller, Sinisa Haberle, Jeannette Vasquez-Vivar, Mark W. Dewhirst, Zeljko Vujaskovic, and Ines Batinic-Haberle. “Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumor.” Free Radic Biol Med 47, no. 7 (October 1, 2009): 992–1004. https://doi.org/10.1016/j.freeradbiomed.2009.07.001.Full Text Link to Item
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Brady, Samuel L., Greta Toncheva, Mark W. Dewhirst, and Terry T. Yoshizumi. “Characterization of a 137Cs irradiator from a new perspective with modern dosimetric tools.” Health Phys 97, no. 3 (September 2009): 195–205. https://doi.org/10.1097/HP.0b013e3181a9bd42.Full Text Link to Item
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Vishwanath, Karthik, Daniel Klein, Kevin Chang, Thies Schroeder, Mark W. Dewhirst, and Nimmi Ramanujam. “Quantitative optical spectroscopy can identify long-term local tumor control in irradiated murine head and neck xenografts.” J Biomed Opt 14, no. 5 (September 2009): 054051. https://doi.org/10.1117/1.3251013.Full Text Link to Item
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Vishwanath, Karthik, Hong Yuan, William T. Barry, Mark W. Dewhirst, and Nimmi Ramanujam. “Using optical spectroscopy to longitudinally monitor physiological changes within solid tumors.” Neoplasia 11, no. 9 (September 2009): 889–900. https://doi.org/10.1593/neo.09580.Full Text Link to Item
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Zhang, Guoqing, Gregory M. Palmer, Mark W. Dewhirst, and Cassandra L. Fraser. “A dual-emissive-materials design concept enables tumour hypoxia imaging.” Nat Mater 8, no. 9 (September 2009): 747–51. https://doi.org/10.1038/nmat2509.Full Text Link to Item
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Zhang, Guoqing, Cassandra L. Fraser, Sarah Hamm-Alvarez, Jiansong Xie, Richard J. Price, Gregory M. Palmer, and Mark W. Dewhirst. “POLY 216-Boron biomaterials for imaging and oxygen sensing.” Abstracts of Papers of the American Chemical Society 238 (August 16, 2009).Link to Item
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Viglianti, Benjamin L., Michael Lora-Michiels, Jeanie M. Poulson, Lan Lan, Daohai Yu, Linda Sanders, Oana Craciunescu, et al. “Dynamic contrast-enhanced magnetic resonance imaging as a predictor of clinical outcome in canine spontaneous soft tissue sarcomas treated with thermoradiotherapy.” Clin Cancer Res 15, no. 15 (August 1, 2009): 4993–5001. https://doi.org/10.1158/1078-0432.CCR-08-2222.Full Text Link to Item
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Kasper, Amanda C., Eui Jung Moon, Xiangqian Hu, Yongho Park, Ceshea M. Wooten, Hyoungsu Kim, Weitao Yang, Mark W. Dewhirst, and Jiyong Hong. “Analysis of HIF-1 inhibition by manassantin A and analogues with modified tetrahydrofuran configurations.” Bioorg Med Chem Lett 19, no. 14 (July 15, 2009): 3783–86. https://doi.org/10.1016/j.bmcl.2009.04.071.Full Text Link to Item
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Kos, Ivan, Júlio S. Rebouças, Gilson DeFreitas-Silva, Daniela Salvemini, Zeljko Vujaskovic, Mark W. Dewhirst, Ivan Spasojević, and Ines Batinić-Haberle. “Lipophilicity of potent porphyrin-based antioxidants: comparison of ortho and meta isomers of Mn(III) N-alkylpyridylporphyrins.” Free Radic Biol Med 47, no. 1 (July 1, 2009): 72–78. https://doi.org/10.1016/j.freeradbiomed.2009.04.002.Full Text Link to Item
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Hardee, Matthew E., Mark W. Dewhirst, Nikita Agarwal, and Brian S. Sorg. “Novel imaging provides new insights into mechanisms of oxygen transport in tumors.” Curr Mol Med 9, no. 4 (May 2009): 435–41. https://doi.org/10.2174/156652409788167122.Full Text Link to Item
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Moon, Eui Jung, Chuan-Yuan Li, Ines Batinic-Haberle, and Mark Dewhirst. “Hyperthermia-induced HIF-1 activation and tumor reoxygenation.” Cancer Research 69 (May 1, 2009).Link to Item
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Pries, Axel R., Annemiek J. M. Cornelissen, Anoek A. Sloot, Marlene Hinkeldey, Matthew R. Dreher, Michael Höpfner, Mark W. Dewhirst, and Timothy W. Secomb. “Structural adaptation and heterogeneity of normal and tumor microvascular networks.” Plos Comput Biol 5, no. 5 (May 2009): e1000394. https://doi.org/10.1371/journal.pcbi.1000394.Full Text Link to Item
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Cheng, Kung-Shan, Yu Yuan, Zhen Li, Paul R. Stauffer, Paolo Maccarini, William T. Joines, Mark W. Dewhirst, and Shiva K. Das. “The performance of a reduced-order adaptive controller when used in multi-antenna hyperthermia treatments with nonlinear temperature-dependent perfusion.” Phys Med Biol 54, no. 7 (April 7, 2009): 1979–95. https://doi.org/10.1088/0031-9155/54/7/008.Full Text Link to Item
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Stakhursky, Vadim L., Omar Arabe, Kung-Shan Cheng, James Macfall, Paolo Maccarini, Oana Craciunescu, Mark Dewhirst, Paul Stauffer, and Shiva K. Das. “Real-time MRI-guided hyperthermia treatment using a fast adaptive algorithm.” Phys Med Biol 54, no. 7 (April 7, 2009): 2131–45. https://doi.org/10.1088/0031-9155/54/7/019.Full Text Link to Item
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Kim, H., A. C. Kasper, E. J. Moon, Y. Park, C. M. Wooten, M. W. Dewhirst, and J. Hong. “Nucleophilic Addition of Organozinc Reagents to 2-Sulfonyl Cyclic Ethers: Stereoselective Synthesis of Manassantins A and B (Org. Lett., (2009) 11:7 (1671-1671).” Organic Letters 11, no. 7 (April 2, 2009): 1671. https://doi.org/10.1021/ol900421x.Full Text
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Zhang, Guoqing, Ruffin E. Evans, Gregory M. Palmer, Mark W. Dewhirst, Jiansong Xie, Sarah Hamm-Alvarez, Richard J. Price, and Cassandra L. Fraser. “Light emitting boron biomaterials for imaging and oxygen sensing.” Abstracts of Papers of the American Chemical Society 237 (March 22, 2009).Link to Item
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Palmer, Gregory M., Ronald J. Viola, Thies Schroeder, Pavel S. Yarmolenko, Mark W. Dewhirst, and Nirmala Ramanujam. “Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo.” J Biomed Opt 14, no. 2 (March 2009): 024010. https://doi.org/10.1117/1.3103586.Full Text Link to Item
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Dewhirst, M. W. “The International Journal of Hyperthermia - The first 25 years.” International Journal of Hyperthermia 25, no. 1 (February 27, 2009): 1–2. https://doi.org/10.1080/02656730802691217.Full Text
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Stauffer, Pr, Oi Craciunescu, P. Maccarini, C. Wyatt, K. Arunachalam, O. Arabe, V. Stakhursky, et al. “Clinical Utility of Magnetic Resonance Thermal Imaging (MRTI) For Realtime Guidance of Deep Hyperthermia.” Proc Spie Int Soc Opt Eng 7181 (February 25, 2009). https://doi.org/10.1117/12.812188.Full Text Link to Item
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Cheng, Kung-Shan, Yu Yuan, Zhen Li, Paul R. Stauffer, William T. Joines, Mark W. Dewhirst, and Shiva K. Das. “Control time reduction using virtual source projection for treating a leg sarcoma with nonlinear perfusion.” Proc Spie Int Soc Opt Eng 7181 (February 12, 2009). https://doi.org/10.1117/12.808499.Full Text Link to Item
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Dewey, William C., Chris J. Diederich, and Mark W. Dewhirst. “Hyperthermia classic commentary: 'Arrhenius relationships from the molecule and cell to the clinic' by William Dewey, Int. J. Hyperthermia, 10:457-483, 1994.” Int J Hyperthermia 25, no. 1 (February 2009): 21–24. https://doi.org/10.1080/02656730902733695.Full Text Link to Item
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Skala, Melissa C., Andrew Fontanella, Hansford Hendargo, Mark W. Dewhirst, and Joseph A. Izatt. “Combined hyperspectral and spectral domain optical coherence tomography microscope for noninvasive hemodynamic imaging.” Opt Lett 34, no. 3 (February 1, 2009): 289–91. https://doi.org/10.1364/ol.34.000289.Full Text Link to Item
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Hardee, Matthew E., Rose J. Eapen, Zahid N. Rabbani, Matthew R. Dreher, Jeffrey Marks, Kimberly L. Blackwell, and Mark W. Dewhirst. “Her2/neu signaling blockade improves tumor oxygenation in a multifactorial fashion in Her2/neu+ tumors.” Cancer Chemother Pharmacol 63, no. 2 (January 2009): 219–28. https://doi.org/10.1007/s00280-008-0729-3.Full Text Link to Item
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Kim, Hyoungsu, Amanda C. Kasper, Eui Jung Moon, Yongho Park, Ceshea M. Wooten, Mark W. Dewhirst, and Jiyong Hong. “Nucleophilic addition of organozinc reagents to 2-sulfonyl cyclic ethers: stereoselective synthesis of manassantins A and B.” Org Lett 11, no. 1 (January 1, 2009): 89–92. https://doi.org/10.1021/ol8024617.Full Text Link to Item
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Craciunescu, Oana I., Kimberly L. Blackwell, Ellen L. Jones, James R. Macfall, Daohai Yu, Zeljko Vujaskovic, Terence Z. Wong, et al. “DCE-MRI parameters have potential to predict response of locally advanced breast cancer patients to neoadjuvant chemotherapy and hyperthermia: a pilot study.” Int J Hyperthermia 25, no. 6 (2009): 405–15. https://doi.org/10.1080/02656730903022700.Full Text Link to Item
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Sonveaux, Pierre, Frédérique Végran, Thies Schroeder, Melanie C. Wergin, Julien Verrax, Zahid N. Rabbani, Christophe J. De Saedeleer, et al. “Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice.” J Clin Invest 118, no. 12 (December 2008): 3930–42. https://doi.org/10.1172/JCI36843.Full Text Link to Item
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Viola, Ronald J., James M. Provenzale, Fang Li, Chuan-Yuan Li, Hong Yuan, Jessica Tashjian, and Mark W. Dewhirst. “In vivo bioluminescence imaging monitoring of hypoxia-inducible factor 1alpha, a promoter that protects cells, in response to chemotherapy.” Ajr Am J Roentgenol 191, no. 6 (December 2008): 1779–84. https://doi.org/10.2214/AJR.07.4060.Full Text Link to Item
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Chen, Julia Ling-Yu, Joseph E. Lucas, Thies Schroeder, Seiichi Mori, Jianli Wu, Joseph Nevins, Mark Dewhirst, Mike West, and Jen-Tsan Chi. “The genomic analysis of lactic acidosis and acidosis response in human cancers.” Plos Genet 4, no. 12 (December 2008): e1000293. https://doi.org/10.1371/journal.pgen.1000293.Full Text Link to Item
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Snyder, S. A., M. W. Dewhirst, and M. L. Hauck. “The role of hypoxia in canine cancer.” Vet Comp Oncol 6, no. 4 (December 2008): 213–23. https://doi.org/10.1111/j.1476-5829.2008.00163.x.Full Text Link to Item
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Mertyna, Pawel, Mark W. Dewhirst, Elkan Halpern, Wallace Goldberg, and S Nahum Goldberg. “Radiofrequency ablation: the effect of distance and baseline temperature on thermal dose required for coagulation.” Int J Hyperthermia 24, no. 7 (November 2008): 550–59. https://doi.org/10.1080/02656730802035662.Full Text Link to Item
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Stein, Rebecca A., Ching-Yi Chang, Dmitri A. Kazmin, James Way, Thies Schroeder, Melanie Wergin, Mark W. Dewhirst, and Donald P. McDonnell. “Estrogen-related receptor alpha is critical for the growth of estrogen receptor-negative breast cancer.” Cancer Res 68, no. 21 (November 1, 2008): 8805–12. https://doi.org/10.1158/0008-5472.CAN-08-1594.Full Text Link to Item
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Kim, E., J. Bowsher, A. S. Thomas, H. Sakhalkar, M. Dewhirst, and M. Oldham. “Improving the quantitative accuracy of optical-emission computed tomography by incorporating an attenuation correction: application to HIF1 imaging.” Phys Med Biol 53, no. 19 (October 7, 2008): 5371–83. https://doi.org/10.1088/0031-9155/53/19/007.Full Text Link to Item
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Dewhirst, Mark W. “Hyperthermia and nanotechnology - a note from the Editor-in-chief.” Int J Hyperthermia 24, no. 6 (September 2008): 449–50. https://doi.org/10.1080/02656730802227236.Full Text Link to Item
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Chen, Qing, Ava Krol, Alex Wright, David Needham, Mark W. Dewhirst, and Fan Yuan. “Tumor microvascular permeability is a key determinant for antivascular effects of doxorubicin encapsulated in a temperature sensitive liposome.” Int J Hyperthermia 24, no. 6 (September 2008): 475–82. https://doi.org/10.1080/02656730701854767.Full Text Link to Item
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Dewhirst, Mark W., Yiting Cao, and Benjamin Moeller. “Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response (vol 8, pg 425, 2008).” Nature Reviews Cancer 8, no. 8 (August 2008).Link to Item
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Dewhirst, Mark. “First international association of hyperthermic oncology Tsudomu Sugahara award.” Int J Hyperthermia 24, no. 5 (August 2008): 442–43. https://doi.org/10.1080/02656730802195052.Full Text Link to Item
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Dewhirst, M. W., Y. Cao, and B. Moeller. “Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response (Nature Reviews Cancer (2008) 8, (425-437)).” Nature Reviews Cancer 8, no. 8 (August 1, 2008): 654. https://doi.org/10.1038/nrc2438.Full Text
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Cárdenas-Navia, Laura I., Daniel Mace, Rachel A. Richardson, David F. Wilson, Siqing Shan, and Mark W. Dewhirst. “The pervasive presence of fluctuating oxygenation in tumors.” Cancer Res 68, no. 14 (July 15, 2008): 5812–19. https://doi.org/10.1158/0008-5472.CAN-07-6387.Full Text Link to Item
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Fitzhugh, David J., Siqing Shan, Mark W. Dewhirst, and Laura P. Hale. “Bromelain treatment decreases neutrophil migration to sites of inflammation.” Clin Immunol 128, no. 1 (July 2008): 66–74. https://doi.org/10.1016/j.clim.2008.02.015.Full Text Link to Item
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Schroeder, Thies, Benjamin L. Viglianti, and Mark W. Dewhirst. “Low-intensity alternating electric fields: a potentially safe and effective treatment of cancer?” Onkologie 31, no. 7 (July 2008): 357–58. https://doi.org/10.1159/000140601.Full Text Link to Item
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Siddiqui, Farzan, Paul R. Avery, Chuan-Yuan Li, Xiuwu Zhang, Susan M. LaRue, Mark W. Dewhirst, and Robert L. Ullrich. “Induction of the human heat shock promoter HSP70B by nutritional stress: implications for cancer gene therapy.” Cancer Invest 26, no. 6 (July 2008): 553–61. https://doi.org/10.1080/07357900701788015.Full Text Link to Item
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Barboriak, Daniel P., James R. MacFall, Benjamin L. Viglianti, and Mark W. Dewhirst Dvm. “Comparison of three physiologically-based pharmacokinetic models for the prediction of contrast agent distribution measured by dynamic MR imaging.” J Magn Reson Imaging 27, no. 6 (June 2008): 1388–98. https://doi.org/10.1002/jmri.21344.Full Text Link to Item
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Dewhirst, Mark W., Yiting Cao, and Benjamin Moeller. “Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response.” Nat Rev Cancer 8, no. 6 (June 2008): 425–37. https://doi.org/10.1038/nrc2397.Full Text Link to Item
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Manzoor, Ashley A., Thies Schroeder, and Mark W. Dewhirst. “One-stop-shop tumor imaging: buy hypoxia, get lactate free.” J Clin Invest 118, no. 5 (May 2008): 1616–19. https://doi.org/10.1172/JCI35543.Full Text Link to Item
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Sarraf-Yazdi, Shiva, Jing Mi, Benjamin J. Moeller, Xilin Niu, Rebekah R. White, Christopher D. Kontos, Bruce A. Sullenger, Mark W. Dewhirst, and Bryan M. Clary. “Inhibition of in vivo tumor angiogenesis and growth via systemic delivery of an angiopoietin 2-specific RNA aptamer.” J Surg Res 146, no. 1 (May 1, 2008): 16–23. https://doi.org/10.1016/j.jss.2007.04.028.Full Text Link to Item
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Pries, Axel R., Annemiek J. M. Cornelissen, Anouk A. Sloot, Matthew Dreher, Marlene Hinkeldey, Michael Hoepfner, Mark W. Dewhirst, and Timothy W. Secomb. “Changed microvascular adaptation characteristics may explain heterogeneity and hypoxia of tumor perfusion.” Faseb Journal 22 (April 1, 2008).Link to Item
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Sarraf-Yazdi, S., J. Mi, M. W. Dewhirst, and B. M. Clary. “Use of bioluminescence imaging to detect enhanced hepatic and systemic tumor growth following partial hepatectomy in mice.” Eur J Surg Oncol 34, no. 4 (April 2008): 476–81. https://doi.org/10.1016/j.ejso.2007.06.001.Full Text Link to Item
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Cheng, Kung-Shan, Vadim Stakhursky, Oana I. Craciunescu, Paul Stauffer, Mark Dewhirst, and Shiva K. Das. “Fast temperature optimization of multi-source hyperthermia applicators with reduced-order modeling of 'virtual sources'.” Phys Med Biol 53, no. 6 (March 21, 2008): 1619–35. https://doi.org/10.1088/0031-9155/53/6/008.Full Text Link to Item
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Kirkpatrick, John P., and Mark W. Dewhirst. “Analytic solution to steady-state radial diffusion of a substrate with first-order reaction kinetics in the tissue of a Krogh's cylinder.” Radiat Res 169, no. 3 (March 2008): 350–54. https://doi.org/10.1667/RR1166.1.Full Text Link to Item
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Oldham, Mark, Harshad Sakhalkar, Tim Oliver, G. Allan Johnson, and Mark Dewhirst. “Optical clearing of unsectioned specimens for three-dimensional imaging via optical transmission and emission tomography.” J Biomed Opt 13, no. 2 (March 2008): 021113. https://doi.org/10.1117/1.2907968.Full Text Link to Item
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Kirkpatrick, John P., Zahid N. Rabbani, Rex C. Bentley, Matt E. Hardee, Seth Karol, Jeffrey Meyer, Egbert Oosterwijk, et al. “Elevated CAIX Expression is Associated with an Increased Risk of Distant Failure in Early-Stage Cervical Cancer.” Biomark Insights 3 (February 1, 2008): 45–55. https://doi.org/10.4137/bmi.s570.Full Text Link to Item
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Tashjian, Jessica A., Mark W. Dewhirst, David Needham, and Benjamin L. Viglianti. “Rationale for and measurement of liposomal drug delivery with hyperthermia using non-invasive imaging techniques.” Int J Hyperthermia 24, no. 1 (February 2008): 79–90. https://doi.org/10.1080/02656730701840147.Full Text Link to Item
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Wong, Terence Z., Jeffrey L. Lacy, Neil A. Petry, Thomas C. Hawk, Thomas A. Sporn, Mark W. Dewhirst, and Gordana Vlahovic. “PET of hypoxia and perfusion with 62Cu-ATSM and 62Cu-PTSM using a 62Zn/62Cu generator.” Ajr Am J Roentgenol 190, no. 2 (February 2008): 427–32. https://doi.org/10.2214/AJR.07.2876.Full Text Link to Item
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Sathornsumetee, Sith, Yiting Cao, Jennifer E. Marcello, James E. Herndon, Roger E. McLendon, Annick Desjardins, Henry S. Friedman, Mark W. Dewhirst, James J. Vredenburgh, and Jeremy N. Rich. “Tumor angiogenic and hypoxic profiles predict radiographic response and survival in malignant astrocytoma patients treated with bevacizumab and irinotecan.” J Clin Oncol 26, no. 2 (January 10, 2008): 271–78. https://doi.org/10.1200/JCO.2007.13.3652.Full Text Link to Item
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Black, R. D., N. G. Bolick, R. A. Richardson, and M. W. Dewhirst. “In vivo monitoring of a fluorescently labeled antibody in mice with breast cancer xenografts.” Ieee Sensors Journal 8, no. 1 (January 1, 2008): 81–88. https://doi.org/10.1109/JSEN.2007.912911.Full Text
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DEWHIRST, M. W. “Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response.” Nat Rev Cancer 8 (2008): 425–37.
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Mi, Jing, Xiuwu Zhang, Zahid N. Rabbani, Yingmiao Liu, Srinevas K. Reddy, Zhen Su, Fawzia K. Salahuddin, et al. “RNA Aptamer-targeted Inhibition of NF-κB Suppresses Non-small Cell Lung Cancer Resistance to Doxorubicin.” Mol Ther 16, no. 1 (January 2008): 66–73. https://doi.org/10.1038/sj.mt.6300320.Full Text Link to Item
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Sorg, Brian S., Matthew E. Hardee, Nikita Agarwal, Benjamin J. Moeller, and Mark W. Dewhirst. “Spectral imaging facilitates visualization and measurements of unstable and abnormal microvascular oxygen transport in tumors.” J Biomed Opt 13, no. 1 (January 2008): 014026. https://doi.org/10.1117/1.2837439.Full Text Link to Item
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Zhou, S. M., E. J. Hoppenworth, S. K. Das, Z. H. Wang, X. J. Sun, F. F. Yin, and M. W. Dewhirst. “Response to comments by Dr. Luijik and Dr. Schippers.” Medical Physics 35, no. 6 (January 1, 2008): 2560. https://doi.org/10.1118/1.2912367.Full Text
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Vishwanath, K., H. Yuan, L. Moore, J. Bender, M. Dewhirst, and N. Ramanujam. “Longitudinal monitoring of 4t1-tumor physiology in vivo with doxorubicin treatment via diffuse optical spectroscopy.” Biomedical Optics, Biomed 2008, January 1, 2008. https://doi.org/10.1364/biomed.2008.btuc3.Full Text
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Dewhirst, M. W. “State of the journal, 2007.” International Journal of Hyperthermia 23, no. 8 (December 1, 2007): 607–8. https://doi.org/10.1080/02656730701836962.Full Text
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Cheng, Kung-Shan, Vadim Stakhursky, Paul Stauffer, Mark Dewhirst, and Shiva K. Das. “Online feedback focusing algorithm for hyperthermia cancer treatment.” Int J Hyperthermia 23, no. 7 (November 2007): 539–54. https://doi.org/10.1080/02656730701678877.Full Text Link to Item
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Rabbani, Zahid N., Fawzia K. Salahuddin, Pavel Yarmolenko, Ines Batinic-Haberle, Bradley A. Thrasher, Benjamin Gauter-Fleckenstein, Mark W. Dewhirst, Mitchell S. Anscher, and Zeljko Vujaskovic. “Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation.” Free Radic Res 41, no. 11 (November 2007): 1273–82. https://doi.org/10.1080/10715760701689550.Full Text Link to Item
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Arabe, O. A., P. F. Maccarini, E. L. Jones, G. Hanna, T. V. Samulski, M. W. Dewhirst, D. E. Thrall, and P. R. Stauffer. “A 400 MHz hyperthermia system using rotating spiral antennas for uniform treatment of large superficial and sub-surface tumors.” Ieee Mtt S International Microwave Symposium Digest, October 2, 2007, 1333–36. https://doi.org/10.1109/MWSYM.2007.380458.Full Text
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Wergin, M., C. G. Willett, and M. W. Dewhirst. “Monitoring changes in the microenvironment during targeted therapies.” Oncology 21, no. 11 (October 1, 2007): 1354–70.
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Zennadi, Rahima, Benjamin J. Moeller, Erin J. Whalen, Milena Batchvarova, Ke Xu, Siqing Shan, Martha Delahunty, Mark W. Dewhirst, and Marilyn J. Telen. “Epinephrine-induced activation of LW-mediated sickle cell adhesion and vaso-occlusion in vivo.” Blood 110, no. 7 (October 1, 2007): 2708–17. https://doi.org/10.1182/blood-2006-11-056101.Full Text Link to Item
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Shan, S., and M. W. Dewhirst. “Corneal Angiogenesis Assay,” September 27, 2007, 203–28. https://doi.org/10.1002/9780470029350.ch11.Full Text
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Vlahovic, G., A. M. Ponce, Z. Rabbani, F. K. Salahuddin, L. Zgonjanin, I. Spasojevic, Z. Vujaskovic, and M. W. Dewhirst. “Treatment with imatinib improves drug delivery and efficacy in NSCLC xenografts.” Br J Cancer 97, no. 6 (September 17, 2007): 735–40. https://doi.org/10.1038/sj.bjc.6603941.Full Text Link to Item
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Gridley, D. S., A. Y. Makinde, X. Luo, A. Rizvi, J. D. Crapo, M. W. Dewhirst, B. J. Moeller, R. D. Pearlstein, and J. M. Slater. “Radiation and a metalloporphyrin radioprotectant in a mouse prostate tumor model.” Anticancer Research 27, no. 5 A (September 1, 2007): 3101–9.
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Gridley, Daila S., Adeola Y. Makinde, Xian Luo, Asma Rizvi, James D. Crapo, Mark W. Dewhirst, Benjamin J. Moeller, Robert D. Pearlstein, and James M. Slater. “Radiation and a metalloporphyrin radioprotectant in a mouse prostate tumor model.” Anticancer Res 27, no. 5A (September 2007): 3101–9.Link to Item
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Davis, Bryce H., Thies Schroeder, Pavel S. Yarmolenko, Farshid Guilak, Mark W. Dewhirst, and Doris A. Taylor. “An in vitro system to evaluate the effects of ischemia on survival of cells used for cell therapy.” Ann Biomed Eng 35, no. 8 (August 2007): 1414–24. https://doi.org/10.1007/s10439-007-9301-2.Full Text Link to Item
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Moon, Eui Jung, David M. Brizel, Jen-Tsan Ashley Chi, and Mark W. Dewhirst. “The potential role of intrinsic hypoxia markers as prognostic variables in cancer.” Antioxid Redox Signal 9, no. 8 (August 2007): 1237–94. https://doi.org/10.1089/ars.2007.1623.Full Text Link to Item
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Das, Shiva K., Sumin Zhou, Junan Zhang, Fang-Fang Yin, Mark W. Dewhirst, and Lawrence B. Marks. “Predicting lung radiotherapy-induced pneumonitis using a model combining parametric Lyman probit with nonparametric decision trees.” Int J Radiat Oncol Biol Phys 68, no. 4 (July 15, 2007): 1212–21. https://doi.org/10.1016/j.ijrobp.2007.03.064.Full Text Link to Item
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Zhou, Su-Min, Shiva K. Das, Zhiheng Wang, Xuejun Sun, Mark Dewhirst, Fang-Fang Yin, and Lawrence B. Marks. “Self-consistent tumor control probability and normal tissue complication probability models based on generalized EUDa).” Med Phys 34, no. 7 (July 2007): 2807–15. https://doi.org/10.1118/1.2740010.Full Text Link to Item
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Dewhirst, M. W. “A note from the Editor-in-Chief.” International Journal of Hyperthermia 23, no. 1 (June 27, 2007): 1–2. https://doi.org/10.1080/02656730601161651.Full Text
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Hardee, Matthew E., Yiting Cao, Ping Fu, Xiaohong Jiang, Yulin Zhao, Zahid N. Rabbani, Zeljko Vujaskovic, Mark W. Dewhirst, and Murat O. Arcasoy. “Erythropoietin blockade inhibits the induction of tumor angiogenesis and progression.” Plos One 2, no. 6 (June 20, 2007): e549. https://doi.org/10.1371/journal.pone.0000549.Full Text Link to Item
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Huang, Julie H., L Isabel Cárdenas-Navia, Charles C. Caldwell, Troy J. Plumb, Caius G. Radu, Paulo N. Rocha, Tuere Wilder, et al. “Requirements for T lymphocyte migration in explanted lymph nodes.” J Immunol 178, no. 12 (June 15, 2007): 7747–55. https://doi.org/10.4049/jimmunol.178.12.7747.Full Text Link to Item
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Dewhirst, Mark W. “In memoriam: Edward L Gillette (1932-2006).” Radiat Res 167, no. 6 (June 2007): 745–47. https://doi.org/10.1667/RRXX01.1.Full Text Link to Item
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Dewhirst, Mark W., Yiting Cao, Chuan Yuan Li, and Benjamin Moeller. “Exploring the role of HIF-1 in early angiogenesis and response to radiotherapy.” Radiother Oncol 83, no. 3 (June 2007): 249–55. https://doi.org/10.1016/j.radonc.2007.05.016.Full Text Link to Item
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Moeller, Benjamin J., Rachel A. Richardson, and Mark W. Dewhirst. “Hypoxia and radiotherapy: opportunities for improved outcomes in cancer treatment.” Cancer Metastasis Rev 26, no. 2 (June 2007): 241–48. https://doi.org/10.1007/s10555-007-9056-0.Full Text Link to Item
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Chi, Sulene L., Miriam L. Wahl, Yvonne M. Mowery, Siqing Shan, Somnath Mukhopadhyay, Susana C. Hilderbrand, Daniel J. Kenan, et al. “Angiostatin-like activity of a monoclonal antibody to the catalytic subunit of F1F0 ATP synthase.” Cancer Res 67, no. 10 (May 15, 2007): 4716–24. https://doi.org/10.1158/0008-5472.CAN-06-1094.Full Text Link to Item
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Cardenas-Navia, L Isabel, Rachel A. Richardson, and Mark W. Dewhirst. “Targeting the molecular effects of a hypoxic tumor microenvironment.” Front Biosci 12 (May 1, 2007): 4061–78. https://doi.org/10.2741/2372.Full Text Link to Item
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Dreher, Matthew R., Wenge Liu, Charles R. Michelich, Mark W. Dewhirst, and Ashutosh Chilkoti. “Thermal cycling enhances the accumulation of a temperature-sensitive biopolymer in solid tumors.” Cancer Res 67, no. 9 (May 1, 2007): 4418–24. https://doi.org/10.1158/0008-5472.CAN-06-4444.Full Text Link to Item
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Sakhalkar, H. S., M. Dewhirst, T. Oliver, Y. Cao, and M. Oldham. “Functional imaging in bulk tissue specimens using optical emission tomography: fluorescence preservation during optical clearing.” Phys Med Biol 52, no. 8 (April 21, 2007): 2035–54. https://doi.org/10.1088/0031-9155/52/8/001.Full Text Link to Item
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Cao, Yiting, Pierre Sonveaux, Shanling Liu, Yulin Zhao, Jing Mi, Bryan M. Clary, Chuan-Yuan Li, Christopher D. Kontos, and Mark W. Dewhirst. “Systemic overexpression of angiopoietin-2 promotes tumor microvessel regression and inhibits angiogenesis and tumor growth.” Cancer Res 67, no. 8 (April 15, 2007): 3835–44. https://doi.org/10.1158/0008-5472.CAN-06-4056.Full Text Link to Item
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Li, Fang, Pierre Sonveaux, Zahid N. Rabbani, Shanling Liu, Bin Yan, Qian Huang, Zeljko Vujaskovic, Mark W. Dewhirst, and Chuan-Yuan Li. “Regulation of HIF-1alpha stability through S-nitrosylation.” Mol Cell 26, no. 1 (April 13, 2007): 63–74. https://doi.org/10.1016/j.molcel.2007.02.024.Full Text Link to Item
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Cárdenas-Navia, L Isabel, Timothy W. Secomb, and Mark W. Dewhirst. “Effects of fluctuating oxygenation on tirapazamine efficacy: Theoretical predictions.” Int J Radiat Oncol Biol Phys 67, no. 2 (February 1, 2007): 581–86. https://doi.org/10.1016/j.ijrobp.2006.10.002.Full Text Link to Item
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Dewhirst, Mark W. “Intermittent hypoxia furthers the rationale for hypoxia-inducible factor-1 targeting.” Cancer Res 67, no. 3 (February 1, 2007): 854–55. https://doi.org/10.1158/0008-5472.CAN-06-4744.Full Text Link to Item
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Rabbani, Zahid N., Ines Batinic-Haberle, Mitchell S. Anscher, Jie Huang, Brian J. Day, Elaine Alexander, Mark W. Dewhirst, and Zeljko Vujaskovic. “Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury.” Int J Radiat Oncol Biol Phys 67, no. 2 (February 1, 2007): 573–80. https://doi.org/10.1016/j.ijrobp.2006.09.053.Full Text Link to Item
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Dewhirst, Mark W., Isabel Cardenas Navia, David M. Brizel, Christopher Willett, and Timothy W. Secomb. “Multiple etiologies of tumor hypoxia require multifaceted solutions.” Clin Cancer Res 13, no. 2 Pt 1 (January 15, 2007): 375–77. https://doi.org/10.1158/1078-0432.CCR-06-2629.Full Text Link to Item
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Ponce, Ana M., Benjamin L. Viglianti, Daohai Yu, Pavel S. Yarmolenko, Charles R. Michelich, Janet Woo, Marcel B. Bally, and Mark W. Dewhirst. “Magnetic resonance imaging of temperature-sensitive liposome release: drug dose painting and antitumor effects.” J Natl Cancer Inst 99, no. 1 (January 3, 2007): 53–63. https://doi.org/10.1093/jnci/djk005.Full Text Link to Item
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Oldham, Mark, Harshad Sakhalkar, Ying Min Wang, Pengyi Guo, Tim Oliver, Rex Bentley, Zeljko Vujaskovic, and Mark Dewhirst. “Three-dimensional imaging of whole rodent organs using optical computed and emission tomography.” J Biomed Opt 12, no. 1 (January 2007): 014009. https://doi.org/10.1117/1.2709858.Full Text Link to Item
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Siddiqui, Farzan, Chuan-Yuan Li, Susan M. Larue, Jean M. Poulson, Paul R. Avery, Amy F. Pruitt, Xiuwu Zhang, et al. “A phase I trial of hyperthermia-induced interleukin-12 gene therapy in spontaneously arising feline soft tissue sarcomas.” Mol Cancer Ther 6, no. 1 (January 2007): 380–89. https://doi.org/10.1158/1535-7163.MCT-06-0342.Full Text Link to Item
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Yan, Bin, Huili Wang, Zahid N. Rabbani, Yulin Zhao, Wenrong Li, Yuqing Yuan, Fang Li, Mark W. Dewhirst, and Chuan-Yuan Li. “Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation.” Cancer Res 66, no. 24 (December 15, 2006): 11565–70. https://doi.org/10.1158/0008-5472.CAN-06-2540.Full Text Link to Item
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Bao, Shideng, Qiulian Wu, Roger E. McLendon, Yueling Hao, Qing Shi, Anita B. Hjelmeland, Mark W. Dewhirst, Darell D. Bigner, and Jeremy N. Rich. “Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.” Nature 444, no. 7120 (December 7, 2006): 756–60. https://doi.org/10.1038/nature05236.Full Text Link to Item
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McGuire, Sarah M., Sumin Zhou, Lawrence B. Marks, Mark Dewhirst, Fang-Fang Yin, and Shiva K. Das. “A methodology for using SPECT to reduce intensity-modulated radiation therapy (IMRT) dose to functioning lung.” Int J Radiat Oncol Biol Phys 66, no. 5 (December 1, 2006): 1543–52. https://doi.org/10.1016/j.ijrobp.2006.07.1377.Full Text Link to Item
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Kleiter, Miriam M., Daohai Yu, Lenore A. Mohammadian, Nelsen Niehaus, Ivan Spasojevic, Linda Sanders, Benjamin L. Viglianti, et al. “A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral doxil extravasation.” Clin Cancer Res 12, no. 22 (November 15, 2006): 6800–6807. https://doi.org/10.1158/1078-0432.CCR-06-0839.Full Text Link to Item
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Viglianti, Benjamin L., Ana M. Ponce, Charles R. Michelich, Daohai Yu, Sheela A. Abraham, Linda Sanders, Pavel S. Yarmolenko, et al. “Chemodosimetry of in vivo tumor liposomal drug concentration using MRI.” Magn Reson Med 56, no. 5 (November 2006): 1011–18. https://doi.org/10.1002/mrm.21032.Full Text Link to Item
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Siddiqui, Farzan, E. J. Ehrhart, Brad Charles, Laura Chubb, Chuan-Yuan Li, Xiuwu Zhang, Susan M. Larue, Paul R. Avery, Mark W. Dewhirst, and Robert L. Ullrich. “Anti-angiogenic effects of interleukin-12 delivered by a novel hyperthermia induced gene construct.” Int J Hyperthermia 22, no. 7 (November 2006): 587–606. https://doi.org/10.1080/02656730600983063.Full Text Link to Item
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Vlahovic, G., Z. N. Rabbani, J. E. Herndon, M. W. Dewhirst, and Z. Vujaskovic. “Treatment with Imatinib in NSCLC is associated with decrease of phosphorylated PDGFR-beta and VEGF expression, decrease in interstitial fluid pressure and improvement of oxygenation.” Br J Cancer 95, no. 8 (October 23, 2006): 1013–19. https://doi.org/10.1038/sj.bjc.6603366.Full Text Open Access Copy Link to Item
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Anscher, Mitchell S., Jennifer Garst, Lawrence B. Marks, Nicole Larrier, Frank Dunphy, James E. Herndon, Robert Clough, et al. “Assessing the ability of the antiangiogenic and anticytokine agent thalidomide to modulate radiation-induced lung injury.” Int J Radiat Oncol Biol Phys 66, no. 2 (October 1, 2006): 477–82. https://doi.org/10.1016/j.ijrobp.2006.05.031.Full Text Link to Item
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Lora-Michiels, Michaël, Daohai Yu, Linda Sanders, Jean M. Poulson, Chieko Azuma, Beth Case, Zeljko Vujaskovic, Donald E. Thrall, H Cecil Charles, and Mark W. Dewhirst. “Extracellular pH and P-31 magnetic resonance spectroscopic variables are related to outcome in canine soft tissue sarcomas treated with thermoradiotherapy.” Clin Cancer Res 12, no. 19 (October 1, 2006): 5733–40. https://doi.org/10.1158/1078-0432.CCR-05-2669.Full Text Link to Item
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Oltean, Sebastian, Brian S. Sorg, Todd Albrecht, Vivian I. Bonano, Robert M. Brazas, Mark W. Dewhirst, and Mariano A. Garcia-Blanco. “Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity.” Proc Natl Acad Sci U S A 103, no. 38 (September 19, 2006): 14116–21. https://doi.org/10.1073/pnas.0603090103.Full Text Link to Item
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Oldham, Mark, Harshad Sakhalkar, Tim Oliver, Ying Min Wang, John Kirpatrick, Yiting Cao, Cristian Badea, G Allan Johnson, and Mark Dewhirst. “Three-dimensional imaging of xenograft tumors using optical computed and emission tomography.” Med Phys 33, no. 9 (September 2006): 3193–3202. https://doi.org/10.1118/1.2217109.Full Text Link to Item
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Yan, B., H. Wang, D. Zhuo, F. Li, T. Kon, M. Dewhirst, and C. -. Y. Li. “Apoptotic DNA fragmentation factor maintains chromosome stability in a P53-independent manner.” Oncogene 25, no. 39 (August 31, 2006): 5370–76. https://doi.org/10.1038/sj.onc.1209535.Full Text Link to Item
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Hicks, Kevin O., Frederik B. Pruijn, Timothy W. Secomb, Michael P. Hay, Richard Hsu, J Martin Brown, William A. Denny, Mark W. Dewhirst, and William R. Wilson. “Use of three-dimensional tissue cultures to model extravascular transport and predict in vivo activity of hypoxia-targeted anticancer drugs.” J Natl Cancer Inst 98, no. 16 (August 16, 2006): 1118–28. https://doi.org/10.1093/jnci/djj306.Full Text Link to Item
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Dewhirst, M. W., D. Thrall, Z. Vujaskovic, D. Yu, E. Jones, and P. Corry. “In Reply to van der Zee et al. [2].” International Journal of Hyperthermia 22, no. 5 (August 1, 2006): 437–46. https://doi.org/10.1080/02656730600768589.Full Text
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Dewhirst, Mark W., Donald Thrall, Zeljko Vujaskovic, Daohai Yu, Ellen Jones, and Peter Corry. “Untitled - Reply.” International Journal of Hyperthermia 22, no. 5 (August 1, 2006): 437–46.Link to Item
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Shan, Siqing, Clay Flowers, Cathy D. Peltz, Heather Sweet, Norbert Maurer, Eun-Joo Gina Kwon, Ave Krol, Fan Yuan, and Mark W. Dewhirst. “Preferential extravasation and accumulation of liposomal vincristine in tumor comparing to normal tissue enhances antitumor activity.” Cancer Chemother Pharmacol 58, no. 2 (August 2006): 245–55. https://doi.org/10.1007/s00280-005-0145-x.Full Text Link to Item
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Thrall, D. E., S. M. Larue, A. F. Pruitt, B. Case, and M. W. Dewhirst. “Changes in tumour oxygenation during fractionated hyperthermia and radiation therapy in spontaneous canine sarcomas.” Int J Hyperthermia 22, no. 5 (August 2006): 365–73. https://doi.org/10.1080/02656730600836386.Full Text Link to Item
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Moeller, B. J., and M. W. Dewhirst. “HIF-1 and tumour radiosensitivity.” Br J Cancer 95, no. 1 (July 3, 2006): 1–5. https://doi.org/10.1038/sj.bjc.6603201.Full Text Link to Item
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Hauck, Marlene L., Susan M. LaRue, William P. Petros, Jean M. Poulson, Daohai Yu, Ivan Spasojevic, Amy F. Pruitt, et al. “Phase I trial of doxorubicin-containing low temperature sensitive liposomes in spontaneous canine tumors.” Clin Cancer Res 12, no. 13 (July 1, 2006): 4004–10. https://doi.org/10.1158/1078-0432.CCR-06-0226.Full Text Link to Item
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Jackson, I. L., I. Batinic-Haberle, P. Sonveaux, M. W. Dewhirst, and Z. Vujaskovic. “ROS production and angiogenic regulation by macrophages in response to heat therapy.” Int J Hyperthermia 22, no. 4 (June 2006): 263–73. https://doi.org/10.1080/02656730600594027.Full Text Link to Item
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Yuan, Hong, Thies Schroeder, James E. Bowsher, Laurence W. Hedlund, Terence Wong, and Mark W. Dewhirst. “Intertumoral differences in hypoxia selectivity of the PET imaging agent 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone).” J Nucl Med 47, no. 6 (June 2006): 989–98.Link to Item
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Kelly, Patrick, Benjamin J. Moeller, Juhi Juneja, Michelle A. Booden, Channing J. Der, Yehia Daaka, Mark W. Dewhirst, Timothy A. Fields, and Patrick J. Casey. “The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.” Proc Natl Acad Sci U S A 103, no. 21 (May 23, 2006): 8173–78. https://doi.org/10.1073/pnas.0510254103.Full Text Link to Item
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Sorg, B. S., M. E. Hardee, B. J. Moeller, and M. W. Dewhirst. “Optical imaging measurements of oxygen transport fluctuations and gradients in tumor microvascular networks.” Progress in Biomedical Optics and Imaging Proceedings of Spie 6088 (May 8, 2006). https://doi.org/10.1117/12.644174.Full Text
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Jones, Ellen, Donald Thrall, Mark W. Dewhirst, and Zeljko Vujaskovic. “Prospective thermal dosimetry: the key to hyperthermia's future.” Int J Hyperthermia 22, no. 3 (May 2006): 247–53. https://doi.org/10.1080/02656730600765072.Full Text Link to Item
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Ponce, Ana M., Zeljko Vujaskovic, Fan Yuan, David Needham, and Mark W. Dewhirst. “Hyperthermia mediated liposomal drug delivery.” Int J Hyperthermia 22, no. 3 (May 2006): 205–13. https://doi.org/10.1080/02656730600582956.Full Text Link to Item
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Thrall, D. E., M. W. Dewhirst, E. L. Jones, Z. Vujaskovic, D. Yu, and O. I. Craciunescu. “A clinically proven, prospective, thermal dose descriptor exists [4].” Clinical Cancer Research 12, no. 6 (March 15, 2006): 1944–46. https://doi.org/10.1158/1078-0432.CCR-05-2446.Full Text
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Dreher, Matthew R., Wenge Liu, Charles R. Michelich, Mark W. Dewhirst, Fan Yuan, and Ashutosh Chilkoti. “Tumor vascular permeability, accumulation, and penetration of macromolecular drug carriers.” J Natl Cancer Inst 98, no. 5 (March 1, 2006): 335–44. https://doi.org/10.1093/jnci/djj070.Full Text Link to Item
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Jones, Ellen, Angeles Alvarez Secord, Leonard R. Prosnitz, Thaddeus V. Samulski, James R. Oleson, Andrew Berchuck, Daniel Clarke-Pearson, John Soper, Mark W. Dewhirst, and Zeljko Vujaskovic. “Intra-peritoneal cisplatin and whole abdomen hyperthermia for relapsed ovarian carcinoma.” Int J Hyperthermia 22, no. 2 (March 2006): 161–72. https://doi.org/10.1080/02656730500515270.Full Text Link to Item
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Sonveaux, Pierre, Timothy J. McMahon, Jonathan S. Stamler, Olivier Feron, and Mark W. Dewhirst. “Oxygen regulation of tumor perfusion by S-nitrosohemoglobin: Implications for radiotherapy.” Acta Clinica Belgica 61, no. 2 (March 1, 2006): 95–95.Link to Item
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Mi, Jing, Shiva Sarraf-Yazdi, Xiuwu Zhang, Yiting Cao, Mark W. Dewhirst, Christopher D. Kontos, Chuan-Yuan Li, and Bryan M. Clary. “A comparison of antiangiogenic therapies for the prevention of liver metastases.” J Surg Res 131, no. 1 (March 2006): 97–104. https://doi.org/10.1016/j.jss.2005.09.008.Full Text Link to Item
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Siddiqui, Farzan, Chuan-Yuan Li, Xiuwu Zhang, Susan M. Larue, Mark W. Dewhirst, Robert L. Ullrich, and Paul R. Avery. “Characterization of a recombinant adenovirus vector encoding heat-inducible feline interleukin-12 for use in hyperthermia-induced gene-therapy.” Int J Hyperthermia 22, no. 2 (March 2006): 117–34. https://doi.org/10.1080/02656730500462309.Full Text Link to Item
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Lanzen, Jennifer, Rod D. Braun, Bruce Klitzman, David Brizel, Timothy W. Secomb, and Mark W. Dewhirst. “Direct demonstration of instabilities in oxygen concentrations within the extravascular compartment of an experimental tumor.” Cancer Res 66, no. 4 (February 15, 2006): 2219–23. https://doi.org/10.1158/0008-5472.CAN-03-2958.Full Text Link to Item
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Hardee, Matthew E., Zahid N. Rabbani, Murat O. Arcasoy, John P. Kirkpatrick, Zeljko Vujaskovic, Mark W. Dewhirst, and Kimberly L. Blackwell. “Erythropoietin inhibits apoptosis in breast cancer cells via an Akt-dependent pathway without modulating in vivo chemosensitivity.” Mol Cancer Ther 5, no. 2 (February 2006): 356–61. https://doi.org/10.1158/1535-7163.MCT-05-0196.Full Text Link to Item
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Kirkpatrick, John P., Matthew E. Hardee, Stacey A. Snyder, Catherine M. Peltz, Yulin Zhao, David M. Brizel, Mark W. Dewhirst, and Kimberly L. Blackwell. “The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma.” Radiat Res 165, no. 2 (February 2006): 192–201. https://doi.org/10.1667/rr3499.1.Full Text Link to Item
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Dressman, Holly K., Christopher Hans, Andrea Bild, John A. Olson, Eric Rosen, P Kelly Marcom, Vlayka B. Liotcheva, et al. “Gene expression profiles of multiple breast cancer phenotypes and response to neoadjuvant chemotherapy.” Clin Cancer Res 12, no. 3 Pt 1 (February 1, 2006): 819–26. https://doi.org/10.1158/1078-0432.CCR-05-1447.Full Text Link to Item
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Yan, Bin, Huili Wang, Yuanlin Peng, Ye Hu, He Wang, Xiuwu Zhang, Qi Chen, Joel S. Bedford, Mark W. Dewhirst, and Chuan-Yuan Li. “A unique role of the DNA fragmentation factor in maintaining genomic stability.” Proc Natl Acad Sci U S A 103, no. 5 (January 31, 2006): 1504–9. https://doi.org/10.1073/pnas.0507779103.Full Text Link to Item
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Batinić-Haberle, Ines, Ivan Spasojević, Robert D. Stevens, Bruce Bondurant, Ayako Okado-Matsumoto, Irwin Fridovich, Zeljko Vujasković, and Mark W. Dewhirst. “New PEG-ylated Mn(III) porphyrins approaching catalytic activity of SOD enzyme.” Dalton Trans, no. 4 (January 28, 2006): 617–24. https://doi.org/10.1039/b513761f.Full Text Link to Item
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Hardee, Matthew E., Murat O. Arcasoy, Kimberly L. Blackwell, John P. Kirkpatrick, and Mark W. Dewhirst. “Erythropoietin biology in cancer.” Clin Cancer Res 12, no. 2 (January 15, 2006): 332–39. https://doi.org/10.1158/1078-0432.CCR-05-1771.Full Text Link to Item
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Adams, David J., Miriam L. Wahl, James L. Flowers, Banalata Sen, Michael Colvin, Mark W. Dewhirst, Govindarajan Manikumar, and Mansukh C. Wani. “Camptothecin analogs with enhanced activity against human breast cancer cells. II. Impact of the tumor pH gradient.” Cancer Chemother Pharmacol 57, no. 2 (January 2006): 145–54. https://doi.org/10.1007/s00280-005-0008-5.Full Text Link to Item
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Ko, Sae Hee, Tomio Ueno, Yasunori Yoshimoto, Jin Soo Yoo, Omar I. Abdel-Wahab, Zeinab Abdel-Wahab, Edward Chu, et al. “Optimizing a novel regional chemotherapeutic agent against melanoma: hyperthermia-induced enhancement of temozolomide cytotoxicity.” Clin Cancer Res 12, no. 1 (January 1, 2006): 289–97. https://doi.org/10.1158/1078-0432.CCR-05-0210.Full Text Link to Item
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Tong, Sheng, Qing Chen, Si-Qing Shan, Mark W. Dewhirst, and Fan Yuan. “Quantitative comparison of the inhibitory effects of GW5638 and tamoxifen on angiogenesis in the cornea pocket assay.” Angiogenesis 9, no. 2 (2006): 53–58. https://doi.org/10.1007/s10456-006-9029-x.Full Text Link to Item
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Hardee, M. E., J. P. Kirkpatrick, S. Shan, S. A. Snyder, Z. Vujaskovic, Z. N. Rabbani, M. W. Dewhirst, and K. L. Blackwell. “Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis.” Br J Cancer 93, no. 12 (December 12, 2005): 1350–55. https://doi.org/10.1038/sj.bjc.6602846.Full Text Link to Item
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Corry, Peter M., and Mark W. Dewhirst. “Thermal medicine, heat shock proteins and cancer.” Int J Hyperthermia 21, no. 8 (December 2005): 675–77. https://doi.org/10.1080/02656730500272856.Full Text Link to Item
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Dewhirst, Mark W., Zeljko Vujaskovic, Ellen Jones, and Donald Thrall. “Re-setting the biologic rationale for thermal therapy.” Int J Hyperthermia 21, no. 8 (December 2005): 779–90. https://doi.org/10.1080/02656730500271668.Full Text Link to Item
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Hart, Justin P., Gloria Broadwater, Zahid Rabbani, Benjamin J. Moeller, Robert Clough, Dale Huang, Gregory A. Sempowski, et al. “Cytokine profiling for prediction of symptomatic radiation-induced lung injury.” Int J Radiat Oncol Biol Phys 63, no. 5 (December 1, 2005): 1448–54. https://doi.org/10.1016/j.ijrobp.2005.05.032.Full Text Link to Item
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Moeller, B. J., and M. W. Dewhirst. “In regard to Arvold et al. (Int J Radiat Oncol Biol Phys 2005;62:207-212).” International Journal of Radiation Oncology, Biology, Physics 63, no. 3 (November 2005): 970–71.
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Moeller, Benjamin J., and Mark W. Dewhirst. “In regard to Arvold et al. (Int J Radiat Oncol Biol Phys 2005;62:207-212).” Int J Radiat Oncol Biol Phys 63, no. 3 (November 1, 2005): 970–71. https://doi.org/10.1016/j.ijrobp.2005.06.019.Full Text Link to Item
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Sorg, Brian S., Cathryn D. Peltz, Bruce Klitzman, and Mark W. Dewhirst. “Method for improved accuracy in endogenous urea recovery marker calibrations for microdialysis in tumors.” J Pharmacol Toxicol Methods 52, no. 3 (November 2005): 341–49. https://doi.org/10.1016/j.vascn.2005.05.004.Full Text Link to Item
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Das, Shiva K., James Macfall, Robert McCauley, Oana Craciunescu, Mark W. Dewhirst, and Thaddeus V. Samulski. “Improved magnetic resonance thermal imaging by combining proton resonance frequency shift (PRFS) and apparent diffusion coefficient (ADC) data.” Int J Hyperthermia 21, no. 7 (November 2005): 657–67. https://doi.org/10.1080/02656730500186346.Full Text Link to Item
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Jones, Ellen L., Leonard R. Prosnitz, Mark W. Dewhirst, Zeljko Vujaskovic, Thaddeus V. Samulski, James R. Oleson, Daohi Yu, et al. “In regard to Vasanathan et al. (Int J Radiat Oncol Biol Phys 2005;61:145-153).” Int J Radiat Oncol Biol Phys 63, no. 2 (October 1, 2005): 644. https://doi.org/10.1016/j.ijrobp.2005.06.017.Full Text Link to Item
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Moeller, Benjamin J., Ines Batinic-Haberle, Ivan Spasojevic, Zahid N. Rabbani, Mitchell S. Anscher, Zeljko Vujaskovic, and Mark W. Dewhirst. “A manganese porphyrin superoxide dismutase mimetic enhances tumor radioresponsiveness.” Int J Radiat Oncol Biol Phys 63, no. 2 (October 1, 2005): 545–52. https://doi.org/10.1016/j.ijrobp.2005.05.026.Full Text Link to Item
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Kim, Seok Jin, Zahid N. Rabbani, Mark W. Dewhirst, Zeljko Vujaskovic, Robin T. Vollmer, Ernst-Gilbert Schreiber, Egbert Oosterwijk, and Michael J. Kelley. “Expression of HIF-1alpha, CA IX, VEGF, and MMP-9 in surgically resected non-small cell lung cancer.” Lung Cancer 49, no. 3 (September 2005): 325–35. https://doi.org/10.1016/j.lungcan.2005.03.036.Full Text Link to Item
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Provenzale, James M., Srinivasan Mukundan, and Mark Dewhirst. “The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.” Ajr Am J Roentgenol 185, no. 3 (September 2005): 763–67. https://doi.org/10.2214/ajr.185.3.01850763.Full Text Link to Item
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Sorg, B. S., B. J. Moeller, O. Donovan, Y. Cao, and M. W. Dewhirst. “Measurement of hemoglobin saturation in tumor microvasculature in preclinical models using hyperspectral imaging.” Progress in Biomedical Optics and Imaging Proceedings of Spie 5694 (August 16, 2005): 74–81. https://doi.org/10.1117/12.585520.Full Text
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Moeller, Benjamin J., Matthew R. Dreher, Zahid N. Rabbani, Thies Schroeder, Yiting Cao, Chuan Y. Li, and Mark W. Dewhirst. “Pleiotropic effects of HIF-1 blockade on tumor radiosensitivity.” Cancer Cell 8, no. 2 (August 2005): 99–110. https://doi.org/10.1016/j.ccr.2005.06.016.Full Text Link to Item
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Thrall, Donald E., Susan M. LaRue, Daohai Yu, Thaddeus Samulski, Linda Sanders, Beth Case, Gary Rosner, et al. “Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy.” Clin Cancer Res 11, no. 14 (July 15, 2005): 5206–14. https://doi.org/10.1158/1078-0432.CCR-05-0091.Full Text Link to Item
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Cao, Yiting, Chuan-Yuan Li, Benjamin J. Moeller, Daohai Yu, Yulin Zhao, Matthew R. Dreher, Siqing Shan, and Mark W. Dewhirst. “Observation of incipient tumor angiogenesis that is independent of hypoxia and hypoxia inducible factor-1 activation.” Cancer Res 65, no. 13 (July 1, 2005): 5498–5505. https://doi.org/10.1158/0008-5472.CAN-04-4553.Full Text Link to Item
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Dewhirst, M. “Lev Aleksandrovish Zil'ber (1894-1966). Life in science.” Europe Asia Studies 57, no. 5 (July 1, 2005): 794–96.Link to Item
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Sorg, Brian S., Benjamin J. Moeller, Owen Donovan, Yiting Cao, and Mark W. Dewhirst. “Hyperspectral imaging of hemoglobin saturation in tumor microvasculature and tumor hypoxia development.” J Biomed Opt 10, no. 4 (July 2005): 44004. https://doi.org/10.1117/1.2003369.Full Text Link to Item
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Schroeder, Thies, Hong Yuan, Benjamin L. Viglianti, Cathryn Peltz, Shubha Asopa, Zeljko Vujaskovic, and Mark W. Dewhirst. “Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat.” Cancer Res 65, no. 12 (June 15, 2005): 5163–71. https://doi.org/10.1158/0008-5472.CAN-04-3900.Full Text Link to Item
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Rabbani, Zahid N., Mitchell S. Anscher, Rodney J. Folz, Emerald Archer, Hong Huang, Liguang Chen, Maria L. Golson, Thaddeus S. Samulski, Mark W. Dewhirst, and Zeljko Vujaskovic. “Overexpression of extracellular superoxide dismutase reduces acute radiation induced lung toxicity.” Bmc Cancer 5 (June 10, 2005): 59. https://doi.org/10.1186/1471-2407-5-59.Full Text Link to Item
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Alvarez Secord, A., E. L. Jones, C. A. Hahn, W. P. Petros, D. Yu, L. J. Havrilesky, J. T. Soper, et al. “Phase I/II trial of intravenous Doxil and whole abdomen hyperthermia in patients with refractory ovarian cancer.” Int J Hyperthermia 21, no. 4 (June 2005): 333–47. https://doi.org/10.1080/02656730500110155.Full Text Link to Item
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Hahn, C. A., E. L. Jones, J. L. Blivin, L. L. Sanders, D. Yu, M. W. Dewhirst, A. A. Secord, and L. R. Prosnitz. “Prospective assessment of quality of life in ovarian cancer patients receiving whole abdomen hyperthermia and liposomal doxorubicin.” Int J Hyperthermia 21, no. 4 (June 2005): 349–57. https://doi.org/10.1080/02656730400022260.Full Text Link to Item
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Kim, S. J., Z. N. Rabbani, R. T. Vollmer, E. G. Schreiber, M. W. Dewhirst, Z. Vujaskovic, and M. J. Kelley. “Expression of phosphorylated epidermal growth factor receptor (p-EGFR) in early stage non-small cell lung cancer: its relationship with overexpression of EGFR and cyclooxygenase-2 (COX-2), and survival.” J Clin Oncol 23, no. 16_suppl (June 2005): 9614.Link to Item
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Sonveaux, Pierre, Andrew M. Kaz, Stacey A. Snyder, Rachel A. Richardson, L Isabel Cárdenas-Navia, Rodney D. Braun, John R. Pawloski, et al. “Oxygen regulation of tumor perfusion by S-nitrosohemoglobin reveals a pressor activity of nitric oxide.” Circ Res 96, no. 10 (May 27, 2005): 1119–26. https://doi.org/10.1161/01.RES.0000168740.04986.a7.Full Text Link to Item
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Anscher, Mitchell S., Liguang Chen, Zahid Rabbani, Song Kang, Nicole Larrier, Hong Huang, Thaddeus V. Samulski, et al. “Recent progress in defining mechanisms and potential targets for prevention of normal tissue injury after radiation therapy.” Int J Radiat Oncol Biol Phys 62, no. 1 (May 1, 2005): 255–59. https://doi.org/10.1016/j.ijrobp.2005.01.040.Full Text Link to Item
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Jones, Ellen L., James R. Oleson, Leonard R. Prosnitz, Thaddeus V. Samulski, Zeljko Vujaskovic, Daohai Yu, Linda L. Sanders, and Mark W. Dewhirst. “Randomized trial of hyperthermia and radiation for superficial tumors.” J Clin Oncol 23, no. 13 (May 1, 2005): 3079–85. https://doi.org/10.1200/JCO.2005.05.520.Full Text Link to Item
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Mazooz, Galit, Tevie Mehlman, Thung-Shen Lai, Charles S. Greenberg, Mark W. Dewhirst, and Michal Neeman. “Development of magnetic resonance imaging contrast material for in vivo mapping of tissue transglutaminase activity.” Cancer Res 65, no. 4 (February 15, 2005): 1369–75. https://doi.org/10.1158/0008-5472.CAN-04-2269.Full Text Link to Item
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Dewhirst, Mark W., Jean M. Poulson, Daohai Yu, Linda Sanders, Michaël Lora-Michiels, Zeljko Vujaskovic, Ellen L. Jones, et al. “Relation between pO2, 31P magnetic resonance spectroscopy parameters and treatment outcome in patients with high-grade soft tissue sarcomas treated with thermoradiotherapy.” Int J Radiat Oncol Biol Phys 61, no. 2 (February 1, 2005): 480–91. https://doi.org/10.1016/j.ijrobp.2004.06.211.Full Text Link to Item
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Biaglow, John, Mark Dewhirst, Dennis Leeper, Randy Burd, and Steve Tuttle. “Factors controlling oxygen utilization.” Adv Exp Med Biol 566 (2005): 317–23. https://doi.org/10.1007/0-387-26206-7_42.Full Text Link to Item
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Peltz, Cathryn, Thies Schroeder, and Mark W. Dewhirst. “Monitoring metabolite gradients in the blood, liver, and tumor after induced hyperglycemia in rats with R3230 flank tumors using microdialysis and bioluminescence imaging.” Adv Exp Med Biol 566 (2005): 343–48. https://doi.org/10.1007/0-387-26206-7_45.Full Text Link to Item
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Craciunescu, O. I., E. L. Jones, K. L. Blackwell, T. Z. Wong, E. L. Rosen, Z. Vujaskovic, J. R. MacFall, et al. “Characterizing tumor changes during neoadjuvant treatment of locally advanced breast cancer patients (LABC) using dynamic-enhanced magnetic resonance imaging (DE-MRI).” Proc. Spie Int. Soc. Opt. Eng. (Usa) 5698, no. 1 (2005): 116–25. https://doi.org/10.1117/12.591173.Full Text Link to Item
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Das, Shiva K., Alan H. Baydush, Sumin Zhou, Moyed Miften, Xiaoli Yu, Oana Craciunescu, Mark Oldham, et al. “Predicting radiotherapy-induced cardiac perfusion defects.” Med Phys 32, no. 1 (January 2005): 19–27. https://doi.org/10.1118/1.1823571.Full Text Link to Item
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Kim, Seok Jin, Zahid N. Rabbani, Robin T. Vollmer, Ernst-Gilbert Schreiber, Egbert Oosterwijk, Mark W. Dewhirst, Zeljko Vujaskovic, and Michael J. Kelley. “Carbonic anhydrase IX in early-stage non-small cell lung cancer.” Clin Cancer Res 10, no. 23 (December 1, 2004): 7925–33. https://doi.org/10.1158/1078-0432.CCR-04-0636.Full Text Link to Item
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Zhang, Xiuwu, Takashi Kon, He Wang, Fang Li, Qian Huang, Zahid N. Rabbani, John P. Kirkpatrick, Zeljko Vujaskovic, Mark W. Dewhirst, and Chuan-Yuan Li. “Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha.” Cancer Res 64, no. 22 (November 15, 2004): 8139–42. https://doi.org/10.1158/0008-5472.CAN-03-2301.Full Text Link to Item
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Secomb, Timothy W., Richard Hsu, Eric Y. H. Park, and Mark W. Dewhirst. “Green's function methods for analysis of oxygen delivery to tissue by microvascular networks.” Ann Biomed Eng 32, no. 11 (November 2004): 1519–29. https://doi.org/10.1114/b:abme.0000049036.08817.44.Full Text Link to Item
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Chen, Qing, Sheng Tong, Mark W. Dewhirst, and Fan Yuan. “Targeting tumor microvessels using doxorubicin encapsulated in a novel thermosensitive liposome.” Mol Cancer Ther 3, no. 10 (October 2004): 1311–17.Link to Item
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Dewhirst, Mark W., Rachel Richardson, Isabel Cardenas-Navia, and Yiting Cao. “The relationship between the tumor physiologic microenvironment and angiogenesis.” Hematol Oncol Clin North Am 18, no. 5 (October 2004): 973–vii. https://doi.org/10.1016/j.hoc.2004.06.006.Full Text Link to Item
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Dreher, Matthew R., Martyna Elas, Kazuhiro Ichikawa, Eugene D. Barth, Ashutosh Chilkoti, Gerald M. Rosen, Howard J. Halpern, and Mark Dewhirst. “Nitroxide conjugate of a thermally responsive elastin-like polypeptide for noninvasive thermometry.” Med Phys 31, no. 10 (October 2004): 2755–62. https://doi.org/10.1118/1.1782677.Full Text Link to Item
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Abdel-Wahab, Omar I., Elizabeth Grubbs, Benjamin L. Viglianti, Tsung-Yen Cheng, Tomio Ueno, SaeHee Ko, Zahid Rabbani, et al. “The role of hyperthermia in regional alkylating agent chemotherapy.” Clin Cancer Res 10, no. 17 (September 1, 2004): 5919–29. https://doi.org/10.1158/1078-0432.CCR-04-0096.Full Text Link to Item
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Cárdenas-Navia, L Isabel, Daohai Yu, Rod D. Braun, David M. Brizel, Timothy W. Secomb, and Mark W. Dewhirst. “Tumor-dependent kinetics of partial pressure of oxygen fluctuations during air and oxygen breathing.” Cancer Res 64, no. 17 (September 1, 2004): 6010–17. https://doi.org/10.1158/0008-5472.CAN-03-0947.Full Text Link to Item
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Jones, E. L., L. R. Prosnitz, M. W. Dewhirst, P. K. Marcom, P. H. Hardenbergh, L. B. Marks, D. M. Brizel, Z. Vujaskovic, and T. A. Buchholz. “Thermochemoradiotherapy improves oxygenation in locally advanced breast cancer.” Women’S Oncology Review 4, no. 3 (September 1, 2004): 221–22. https://doi.org/10.1080/14733400400012958.Full Text
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Moeller, Benjamin J., and Mark W. Dewhirst. “Raising the bar: how HIF-1 helps determine tumor radiosensitivity.” Cell Cycle 3, no. 9 (September 2004): 1107–10.Link to Item
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Poulson, J. M., Z. Vujaskovic, A. A. Gaskin, S. M. Larue, R. E. Meyer, D. M. Prescott, T. V. Samulski, D. E. Thrall, and M. W. Dewhirst. “Effect of calcitonin gene related peptide vs sodium nitroprusside to increase temperature in spontaneous canine tumours during local hyperthermia.” Int J Hyperthermia 20, no. 5 (August 2004): 477–89. https://doi.org/10.1080/0265673032000173906.Full Text Link to Item
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Sarraf-Yazdi, Shiva, Jing Mi, Mark W. Dewhirst, and Bryan M. Clary. “Use of in vivo bioluminescence imaging to predict hepatic tumor burden in mice.” J Surg Res 120, no. 2 (August 2004): 249–55. https://doi.org/10.1016/j.jss.2004.03.013.Full Text Link to Item
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Hardee, M. E., J. P. Kirkpatrick, S. Snyder, S. Shan, Z. Vujaskovic, Z. N. Rabbani, M. W. Dewhirst, and K. L. Blackwell. “Erythropoietin (EPO) has no direct effect on tumor growth or angiogenesis in animal models.” J Clin Oncol 22, no. 14_suppl (July 15, 2004): 9530.Link to Item
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Jones, E. L., L. R. Prosnitz, T. V. Samulski, J. Soper, A. Berchuck, D. Clarke-Pearson, M. W. Dewhirst, and Z. Vujaskovic. “Intraperitoneal cisplatin and whole abdomen hyperthermia for relapsed ovarian carcinoma.” J Clin Oncol 22, no. 14_suppl (July 15, 2004): 5038.Link to Item
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Secord, A. A., E. Jones, C. A. Hahn, L. J. Havrilesky, J. T. Soper, A. Berchuck, D. L. Clarke-Pearson, L. R. Prosnitz, and M. W. Dewhirst. “Phase I/II trial of intravenous liposomal doxorubicin and whole abdomen hyperthermia in patients with refractory ovarian cancer.” J Clin Oncol 22, no. 14_suppl (July 15, 2004): 5089.Link to Item
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Blackwell, Kimberly, Herbert Hurwitz, Grazyna Liebérman, William Novotny, Stacey Snyder, Mark Dewhirst, and Charles Greenberg. “Circulating D-dimer levels are better predictors of overall survival and disease progression than carcinoembryonic antigen levels in patients with metastatic colorectal carcinoma.” Cancer 101, no. 1 (July 1, 2004): 77–82. https://doi.org/10.1002/cncr.20336.Full Text Link to Item
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Jones, Ellen L., Leonard R. Prosnitz, Mark W. Dewhirst, P Kelly Marcom, Patricia H. Hardenbergh, Lawrence B. Marks, David M. Brizel, and Zeljko Vujaskovic. “Thermochemoradiotherapy improves oxygenation in locally advanced breast cancer.” Clin Cancer Res 10, no. 13 (July 1, 2004): 4287–93. https://doi.org/10.1158/1078-0432.CCR-04-0133.Full Text Link to Item
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Kirkpatrick, J. P., L. I. Cárdenas-Navia, and M. W. Dewhirst. “Predicting the effect of temporal variations in PO2 on tumor radiosensitivity.” Int J Radiat Oncol Biol Phys 59, no. 3 (July 1, 2004): 822–33. https://doi.org/10.1016/j.ijrobp.2004.02.015.Full Text Link to Item
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Moeller, Benjamin J., Yiting Cao, Zeljko Vujaskovic, Chuan Y. Li, Zishan A. Haroon, and Mark W. Dewhirst. “The relationship between hypoxia and angiogenesis.” Semin Radiat Oncol 14, no. 3 (July 2004): 215–21. https://doi.org/10.1016/j.semradonc.2004.04.005.Full Text Link to Item
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Blackwell, Kimberly L., Mark W. Dewhirst, Vlayka Liotcheva, Stacey Snyder, Gloria Broadwater, Rex Bentley, Anita Lal, et al. “HER-2 gene amplification correlates with higher levels of angiogenesis and lower levels of hypoxia in primary breast tumors.” Clin Cancer Res 10, no. 12 Pt 1 (June 15, 2004): 4083–88. https://doi.org/10.1158/1078-0432.CCR-03-0695.Full Text Link to Item
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Secomb, Timothy W., Richard Hsu, and Mark W. Dewhirst. “Synergistic effects of hyperoxic gas breathing and reduced oxygen consumption on tumor oxygenation: a theoretical model.” Int J Radiat Oncol Biol Phys 59, no. 2 (June 1, 2004): 572–78. https://doi.org/10.1016/j.ijrobp.2004.01.039.Full Text Link to Item
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Viglianti, Benjamin L., Sheela A. Abraham, Charles R. Michelich, Pavel S. Yarmolenko, James R. MacFall, Marcel B. Bally, and Mark W. Dewhirst. “In vivo monitoring of tissue pharmacokinetics of liposome/drug using MRI: illustration of targeted delivery.” Magn Reson Med 51, no. 6 (June 2004): 1153–62. https://doi.org/10.1002/mrm.20074.Full Text Link to Item
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Das, S. K., M. M. Miften, S. Zhou, M. Bell, M. T. Munley, C. S. Whiddon, O. Craciunescu, et al. “Feasibility of optimizing the dose distribution in lung tumors using fluorine-18-fluorodeoxyglucose positron emission tomography and single photon emission computed tomography guided dose prescriptions.” Med Phys 31, no. 6 (June 2004): 1452–61. https://doi.org/10.1118/1.1750991.Full Text Link to Item
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Moeller, Benjamin J., Yiting Cao, Chuan Y. Li, and Mark W. Dewhirst. “Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors: role of reoxygenation, free radicals, and stress granules.” Cancer Cell 5, no. 5 (May 2004): 429–41. https://doi.org/10.1016/s1535-6108(04)00115-1.Full Text Link to Item
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Ward, Erika R., Laurence W. Hedlund, William C. Kurylo, Charles T. Wheeler, Gary P. Cofer, Mark W. Dewhirst, Lawrence B. Marks, and Zeljko Vujaskovic. “Proton and hyperpolarized helium magnetic resonance imaging of radiation-induced lung injury in rats.” Int J Radiat Oncol Biol Phys 58, no. 5 (April 1, 2004): 1562–69. https://doi.org/10.1016/j.ijrobp.2003.12.010.Full Text Link to Item
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Shan, Siqing, Nicole D. Robson, Yiting Cao, Tong Qiao, Chuan Y. Li, Christopher D. Kontos, Mariano Garcia-Blanco, and Mark W. Dewhirst. “Responses of vascular endothelial cells to angiogenic signaling are important for tumor cell survival.” Faseb J 18, no. 2 (February 2004): 326–28. https://doi.org/10.1096/fj.03-0765fje.Full Text Link to Item
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Peters, Kevin G., Christopher D. Kontos, P Charles Lin, Adrianne L. Wong, Prema Rao, Liwen Huang, Mark W. Dewhirst, and Sabita Sankar. “Functional significance of Tie2 signaling in the adult vasculature.” Recent Prog Horm Res 59 (2004): 51–71. https://doi.org/10.1210/rp.59.1.51.Full Text Link to Item
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Eu, Jerry P., Joshua M. Hare, Douglas T. Hess, Michel Skaf, Junhui Sun, Isabella Cardenas-Navina, Qi-An Sun, Mark Dewhirst, Gerhard Meissner, and Jonathan S. Stamler. “Concerted regulation of skeletal muscle contractility by oxygen tension and endogenous nitric oxide.” Proc Natl Acad Sci U S A 100, no. 25 (December 9, 2003): 15229–34. https://doi.org/10.1073/pnas.2433468100.Full Text Link to Item
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Kang, Song K., Zahid N. Rabbani, Rodney J. Folz, Maria L. Golson, Hong Huang, Daohai Yu, Thaddeus S. Samulski, Mark W. Dewhirst, Mitchell S. Anscher, and Zeljko Vujaskovic. “Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury.” Int J Radiat Oncol Biol Phys 57, no. 4 (November 15, 2003): 1056–66. https://doi.org/10.1016/s0360-3016(03)01369-5.Full Text Link to Item
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Rosen, Eric L., Kimberly L. Blackwell, Jay A. Baker, Mary Scott Soo, Rex C. Bentley, Daohai Yu, Thaddeus V. Samulski, and Mark W. Dewhirst. “Accuracy of MRI in the detection of residual breast cancer after neoadjuvant chemotherapy.” Ajr Am J Roentgenol 181, no. 5 (November 2003): 1275–82. https://doi.org/10.2214/ajr.181.5.1811275.Full Text Link to Item
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Blackwell, Kimberly L., John P. Kirkpatrick, Stacey A. Snyder, Gloria Broadwater, Francis Farrell, Linda Jolliffe, David M. Brizel, and Mark W. Dewhirst. “Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin.” Cancer Res 63, no. 19 (October 1, 2003): 6162–65.Link to Item
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Dewhirst, Mark W., and Penny K. Sneed. “Those in gene therapy should pay closer attention to lessons from hyperthermia.” Int J Radiat Oncol Biol Phys 57, no. 2 (October 1, 2003): 597–99. https://doi.org/10.1016/s0360-3016(03)00421-8.Full Text Link to Item
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Flowers, James L., Robert M. Hoffman, Timothy A. Driscoll, Monroe E. Wall, Mansukh C. Wani, Govindarajan Manikumar, Henry S. Friedman, Mark Dewhirst, O Michael Colvin, and David J. Adams. “The activity of camptothecin analogues is enhanced in histocultures of human tumors and human tumor xenografts by modulation of extracellular pH.” Cancer Chemother Pharmacol 52, no. 3 (September 2003): 253–61. https://doi.org/10.1007/s00280-003-0635-7.Full Text Link to Item
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Vujaskovic, Z., E. L. Rosen, K. L. Blackwell, E. L. Jones, D. M. Brizel, L. R. Prosnitz, T. V. Samulski, and M. W. Dewhirst. “Ultrasound guided pO2 measurement of breast cancer reoxygenation after neoadjuvant chemotherapy and hyperthermia treatment.” Int J Hyperthermia 19, no. 5 (September 2003): 498–506. https://doi.org/10.1080/0265673031000121517.Full Text Link to Item
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Erickson, Kristian, Rod D. Braun, Daohai Yu, Jennifer Lanzen, David Wilson, David M. Brizel, Timothy W. Secomb, John E. Biaglow, and Mark W. Dewhirst. “Effect of longitudinal oxygen gradients on effectiveness of manipulation of tumor oxygenation.” Cancer Res 63, no. 15 (August 1, 2003): 4705–12.Link to Item
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Nair, Smita, David Boczkowski, Benjamin Moeller, Mark Dewhirst, Johannes Vieweg, and Eli Gilboa. “Synergy between tumor immunotherapy and antiangiogenic therapy.” Blood 102, no. 3 (August 1, 2003): 964–71. https://doi.org/10.1182/blood-2002-12-3738.Full Text Link to Item
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Voss, Miranda, Jose Pinheiro, James Reynolds, Rebecca Greene, Mark Dewhirst, Steven N. Vaslef, Erik Clary, and W Steve Eubanks. “Endoscopic components separation for abdominal compartment syndrome.” Am J Surg 186, no. 2 (August 2003): 158–63. https://doi.org/10.1016/s0002-9610(03)00171-5.Full Text Link to Item
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Jones, Ellen L., Thaddeus V. Samulski, Mark W. Dewhirst, Angeles Alvarez-Secord, Andrew Berchuck, Daniel Clarke-Pearson, Laura J. Havrilesky, John Soper, and Leonard R. Prosnitz. “A pilot Phase II trial of concurrent radiotherapy, chemotherapy, and hyperthermia for locally advanced cervical carcinoma.” Cancer 98, no. 2 (July 15, 2003): 277–82. https://doi.org/10.1002/cncr.11475.Full Text Link to Item
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Lockhart, A Craig, Rod D. Braun, Daohai Yu, Joel R. Ross, Mark W. Dewhirst, Bruce Klitzman, Fan Yuan, et al. “A clinical model of dermal wound angiogenesis.” Wound Repair Regen 11, no. 4 (July 2003): 306–13. https://doi.org/10.1046/j.1524-475x.2003.11411.x.Full Text Link to Item
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Dewhirst, Mark W., Benjamin L. Viglianti, Michael Lora-Michiels, P Jack Hoopes, and Margaret Hanson. “THERMAL DOSE REQUIREMENT FOR TISSUE EFFECT: EXPERIMENTAL AND CLINICAL FINDINGS.” Proc Spie Int Soc Opt Eng 4954 (June 2, 2003): 37. https://doi.org/10.1117/12.476637.Full Text Link to Item
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Dewhirst, M. W. “A summary report on the reorganization of cancer and radiobiology teaching for radiation oncology residents.” Radiation Research 159, no. 5 (May 1, 2003): 698–701. https://doi.org/10.1667/0033-7587(2003)159[0698:ASROTR]2.0.CO;2.Full Text
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Dewhirst, M. W., B. L. Viglianti, M. Lora-Michiels, M. Hanson, and P. J. Hoopes. “Basic principles of thermal dosimetry and thermal thresholds for tissue damage from hyperthermia.” Int J Hyperthermia 19, no. 3 (May 2003): 267–94. https://doi.org/10.1080/0265673031000119006.Full Text Link to Item
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Dewhirst, M. W., M. Lora-Michiels, B. L. Viglianti, W. C. Dewey, and M. Repacholi. “Carcinogenic effects of hyperthermia.” Int J Hyperthermia 19, no. 3 (May 2003): 236–51. https://doi.org/10.1080/0265673031000070811.Full Text Link to Item
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Goldstein, L. S., M. W. Dewhirst, M. Repacholi, and L. Kheifets. “Summary, conclusions and recommendations: adverse temperature levels in the human body.” Int J Hyperthermia 19, no. 3 (May 2003): 373–84. https://doi.org/10.1080/0265673031000090701.Full Text Link to Item
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White, Rebekah R., Siqing Shan, Christopher P. Rusconi, Geetha Shetty, Mark W. Dewhirst, Christopher D. Kontos, and Bruce A. Sullenger. “Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2.” Proc Natl Acad Sci U S A 100, no. 9 (April 29, 2003): 5028–33. https://doi.org/10.1073/pnas.0831159100.Full Text Link to Item
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Amin, Khalid, Jie Li, Wan Ru Chao, Mark W. Dewhirst, and Zishan A. Haroon. “Dietary glycine inhibits angiogenesis during wound healing and tumor growth.” Cancer Biol Ther 2, no. 2 (March 2003): 173–78. https://doi.org/10.4161/cbt.2.2.280.Full Text Link to Item
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Kirkpatrick, John P., David M. Brizel, and Mark W. Dewhirst. “A mathematical model of tumor oxygen and glucose mass transport and metabolism with complex reaction kinetics.” Radiat Res 159, no. 3 (March 2003): 336–44. https://doi.org/10.1667/0033-7587(2003)159[0336:ammoto]2.0.co;2.Full Text Link to Item
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Krol, A., M. W. Dewhirst, and F. Yuan. “Effects of cell damage and glycosaminoglycan degradation on available extravascular space of different dextrans in a rat fibrosarcoma.” Int J Hyperthermia 19, no. 2 (March 2003): 154–64. https://doi.org/10.1080/02656730210166519.Full Text Link to Item
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Shan, Siqing, Brian Sorg, and Mark W. Dewhirst. “A novel rodent mammary window of orthotopic breast cancer for intravital microscopy.” Microvasc Res 65, no. 2 (March 2003): 109–17. https://doi.org/10.1016/s0026-2862(02)00017-1.Full Text Link to Item
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Zhang, Xiuwu, Yongping Li, Qian Huang, He Wang, Bin Yan, Mark W. Dewhirst, and Chuan-Yuan Li. “Increased resistance of tumor cells to hyperthermia mediated by integrin-linked kinase.” Clin Cancer Res 9, no. 3 (March 2003): 1155–60.Link to Item
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Lockhart, A Craig, Rod D. Braun, Daohai Yu, Joel R. Ross, Mark W. Dewhirst, Jeffrey S. Humphrey, Seth Thompson, et al. “Reduction of wound angiogenesis in patients treated with BMS-275291, a broad spectrum matrix metalloproteinase inhibitor.” Clin Cancer Res 9, no. 2 (February 2003): 586–93.Link to Item
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Biaglow, John E., Intae Lee, Jerry Donahue, Kathy Held, John Mieyal, Mark Dewhirst, and Steve Tuttle. “Glutathione depletion or radiation treatment alters respiration and induces apoptosis in R3230Ac mammary carcinoma.” Adv Exp Med Biol 530 (2003): 153–64. https://doi.org/10.1007/978-1-4615-0075-9_15.Full Text Link to Item
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Cárdenas-Navia, L Isabel, Rod Braun, Kristina Lewis, and Mark Dewhirst. “Comparison of fluctuations of oxygen tension in FSA, 9L, and R3230AC tumors in rats.” Adv Exp Med Biol 510 (2003): 7–12. https://doi.org/10.1007/978-1-4615-0205-0_2.Full Text Link to Item
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Dewhirst, Mark W. “Mechanisms underlying hypoxia development in tumors.” Adv Exp Med Biol 510 (2003): 51–56. https://doi.org/10.1007/978-1-4615-0205-0_9.Full Text Link to Item
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Lee, Intae, Jerry D. Glickson, Mark W. Dewhirst, Dennis B. Leeper, Randy Burd, Harish Poptani, Lydie Nadal, W Gillies McKenna, and John E. Biaglow. “Effect of mild hyperglycemia +/- meta-iodo-benzylguanidine on the radiation response of R3230 Ac tumors.” Adv Exp Med Biol 530 (2003): 177–86. https://doi.org/10.1007/978-1-4615-0075-9_17.Full Text Link to Item
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Richardson, Rachel A., and Mark W. Dewhirst. “The effect of nicotinamide & hyperoxic gases on blood glucose.” Adv Exp Med Biol 510 (2003): 375–78. https://doi.org/10.1007/978-1-4615-0205-0_62.Full Text Link to Item
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Li, C. Y., and M. W. Dewhirst. “Hyperthermia-regulated immunogene therapy.” Int J Hyperthermia 18, no. 6 (November 2002): 586–96. https://doi.org/10.1080/0265673021000017082.Full Text Link to Item
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Zeman, Elaine M., Joseph R. Dynlacht, Barry S. Rosenstein, Mark W. Dewhirst, and Mark W. ASTRO Joint Working Group on Radiobiology Teaching. “Toward a national consensus: teaching radiobiology to radiation oncology residents.” Int J Radiat Oncol Biol Phys 54, no. 3 (November 1, 2002): 861–72. https://doi.org/10.1016/s0360-3016(02)02968-1.Full Text Link to Item
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SCOPE Steering Committee and Subcommittees, U. “Report of the American Society for Therapeutic Radiology and Oncology Working Group on the scope of radiation oncology (SCOPE).” Int J Radiat Oncol Biol Phys 54, no. 2 (October 1, 2002): 317–26. https://doi.org/10.1016/s0360-3016(02)03745-8.Full Text Link to Item
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Vujaskovic, Zeljko, Ines Batinic-Haberle, Zahid N. Rabbani, Qin-fu Feng, Song K. Kang, Ivan Spasojevic, Thaddeus V. Samulski, Irwin Fridovich, Mark W. Dewhirst, and Mitchell S. Anscher. “A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.” Free Radic Biol Med 33, no. 6 (September 15, 2002): 857–63. https://doi.org/10.1016/s0891-5849(02)00980-2.Full Text Link to Item
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Wong, Christopher W., Chun Song, Maggie M. Grimes, Weili Fu, Mark W. Dewhirst, Ruth J. Muschel, and Abu-Bakr Al-Mehdi. “Intravascular location of breast cancer cells after spontaneous metastasis to the lung.” Am J Pathol 161, no. 3 (September 2002): 749–53. https://doi.org/10.1016/S0002-9440(10)64233-2.Full Text Link to Item
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Dynlacht, Joseph R., Mark W. Dewhirst, Eric J. Hall, Barry S. Rosenstein, and Elaine M. Zeman. “Toward a consensus on radiobiology teaching to radiation oncology residents.” Radiat Res 157, no. 5 (May 2002): 599–606. https://doi.org/10.1667/0033-7587(2002)157[0599:tacort]2.0.co;2.Full Text Link to Item
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Kavanagh, Brian D., Timothy W. Secomb, Richard Hsu, Peck Sun Lin, Jurgen Venitz, and Mark W. Dewhirst. “A theoretical model for the effects of reduced hemoglobin-oxygen affinity on tumor oxygenation.” Int J Radiat Oncol Biol Phys 53, no. 1 (May 1, 2002): 172–79. https://doi.org/10.1016/s0360-3016(02)02740-2.Full Text Link to Item
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Hale, Laura P., Rod D. Braun, William M. Gwinn, Paula K. Greer, and Mark W. Dewhirst. “Hypoxia in the thymus: role of oxygen tension in thymocyte survival.” Am J Physiol Heart Circ Physiol 282, no. 4 (April 2002): H1467–77. https://doi.org/10.1152/ajpheart.00682.2001.Full Text Link to Item
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Haroon, Zishan A., Khalid Amin, Wilfred Saito, William Wilson, Charles S. Greenberg, and Mark W. Dewhirst. “SU5416 delays wound healing through inhibition of TGF-beta 1 activation.” Cancer Biol Ther 1, no. 2 (March 2002): 121–26. https://doi.org/10.4161/cbt.55.Full Text Link to Item
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Dewhirst, M. W. “Hyperthermia and the Immune System.” International Journal of Hyperthermia 18, no. 6 (January 1, 2002): 485. https://doi.org/10.1080/0265673021000036522.Full Text
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Dewhirst, Mark W., S. Shan, Yiting Cao, Benjamin Moeller, Fan Yuan, and Chuan-Yuan Li. “Intravital fluorescence facilitates measurement of multiple physiologic functions and gene expression in tumors of live animals.” Dis Markers 18, no. 5–6 (2002): 293–311. https://doi.org/10.1155/2002/820102.Full Text Link to Item
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Vujaskovic, Z., I. Batinic-Haberle, Z. N. Rabbani, I. Spasojevic, T. V. Samulski, I. Fridovich, M. W. Dewhirst, and M. S. Anscher. “Effects of metalloporphyrin catalytic antioxidant AEOL 10113 on radiation-induced lung injury.” Free Radical Biology and Medicine 33 (January 1, 2002): S239–S239.Link to Item
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Needham, D., and M. W. Dewhirst. “The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors.” Adv Drug Deliv Rev 53, no. 3 (December 31, 2001): 285–305. https://doi.org/10.1016/s0169-409x(01)00233-2.Full Text Link to Item
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Dewhirst, M. “Archives of Russia: A directory and bibliographic guide to holdings in Moscow and St. Petersburg.” Europe Asia Studies 53, no. 8 (December 1, 2001): 1275–1275.Link to Item
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Müller, P., G. L. Rosner, L. Y. T. Inoue, and M. W. Dewhirst. “A bayesian model for detecting acute change in nonlinear profiles.” Journal of the American Statistical Association 96, no. 456 (December 1, 2001): 1215–22. https://doi.org/10.1198/016214501753381869.Full Text
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Amin, K., J. Li, M. W. Dewhirst, and Z. A. Haroon. “Dietary glycine reduces wound healing response and tumor growth by inhibition of angiogenesis: Introduction of a new method to screen anti- and pro-angiogenic compounds.” Clinical Cancer Research 7, no. 11 (November 1, 2001): 3704S-3704S.Link to Item
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Ettinger, S. N., C. C. Poellmann, N. A. Wisniewski, A. A. Gaskin, J. S. Shoemaker, J. M. Poulson, M. W. Dewhirst, and B. Klitzman. “Urea as a recovery marker for quantitative assessment of tumor interstitial solutes with microdialysis.” Cancer Res 61, no. 21 (November 1, 2001): 7964–70.Link to Item
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Lohr, F., Q. Huang, K. Hu, M. W. Dewhirst, and C. Y. Li. “Systemic vector leakage and transgene expression by intratumorally injected recombinant adenovirus vectors.” Clin Cancer Res 7, no. 11 (November 2001): 3625–28.Link to Item
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Pogue, B. W., R. D. Braun, J. L. Lanzen, C. Erickson, and M. W. Dewhirst. “Analysis of the heterogeneity of pO2 dynamics during photodynamic therapy with verteporfin.” Photochem Photobiol 74, no. 5 (November 2001): 700–706. https://doi.org/10.1562/0031-8655(2001)074<0700:aothop>2.0.co;2.Full Text Link to Item
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Poulson, J. M., M. W. Dewhirst, A. A. Gaskin, Z. Vujaskovic, T. V. Samulski, D. M. Prescott, R. E. Meyer, R. L. Page, and D. E. Thrall. “Acute pancreatitis associated with administration of a nitric oxide synthase inhibitor in tumor-bearing dogs (vol 14, pg 709, 2000).” In Vivo 15, no. 6 (November 1, 2001).Link to Item
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Shan, S., K. Hu, W. Saito, C. Li, and M. W. Dewhirst. “Effects of soluble Tie-2 receptor and bFGF on GFP-4T1 tumor growth and initiation of angiogenesis in BALB/C mouse dorsal skinfold window chamber.” Clinical Cancer Research 7, no. 11 (November 1, 2001): 3658S-3658S.Link to Item
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Walenta, S., S. Snyder, Z. A. Haroon, R. D. Braun, K. Amin, D. Brizel, W. Mueller-Klieser, B. Chance, and M. W. Dewhirst. “Tissue gradients of energy metabolites mirror oxygen tension gradients in a rat mammary carcinoma model.” Int J Radiat Oncol Biol Phys 51, no. 3 (November 1, 2001): 840–48. https://doi.org/10.1016/s0360-3016(01)01700-x.Full Text Link to Item
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Snyder, S. A., J. L. Lanzen, R. D. Braun, G. Rosner, T. W. Secomb, J. Biaglow, D. M. Brizel, and M. W. Dewhirst. “Simultaneous administration of glucose and hyperoxic gas achieves greater improvement in tumor oxygenation than hyperoxic gas alone.” Int J Radiat Oncol Biol Phys 51, no. 2 (October 1, 2001): 494–506. https://doi.org/10.1016/s0360-3016(01)01654-6.Full Text Link to Item
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Brizel, D. M., T. Schroeder, R. L. Scher, S. Walenta, R. W. Clough, M. W. Dewhirst, and W. Mueller-Klieser. “Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer.” Int J Radiat Oncol Biol Phys 51, no. 2 (October 1, 2001): 349–53. https://doi.org/10.1016/s0360-3016(01)01630-3.Full Text Link to Item
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Lal, A., H. Peters, B. St Croix, Z. A. Haroon, M. W. Dewhirst, R. L. Strausberg, J. H. Kaanders, A. J. van der Kogel, and G. J. Riggins. “Transcriptional response to hypoxia in human tumors.” J Natl Cancer Inst 93, no. 17 (September 5, 2001): 1337–43. https://doi.org/10.1093/jnci/93.17.1337.Full Text Link to Item
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Tozer, G. M., V. E. Prise, J. Wilson, M. Cemazar, S. Shan, M. W. Dewhirst, P. R. Barber, B. Vojnovic, and D. J. Chaplin. “Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability.” Cancer Res 61, no. 17 (September 1, 2001): 6413–22.Link to Item
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Shan, S., A. C. Lockhart, W. Y. Saito, A. M. Knapp, K. R. Laderoute, and M. W. Dewhirst. “The novel tubulin-binding drug BTO-956 inhibits R3230AC mammary carcinoma growth and angiogenesis in Fischer 344 rats.” Clin Cancer Res 7, no. 8 (August 2001): 2590–96.Link to Item
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Vujaskovic, Z., M. S. Anscher, Q. F. Feng, Z. N. Rabbani, K. Amin, T. S. Samulski, M. W. Dewhirst, and Z. A. Haroon. “Radiation-induced hypoxia may perpetuate late normal tissue injury.” Int J Radiat Oncol Biol Phys 50, no. 4 (July 15, 2001): 851–55. https://doi.org/10.1016/s0360-3016(01)01593-0.Full Text Link to Item
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Meyer, D. E., B. C. Shin, G. A. Kong, M. W. Dewhirst, and A. Chilkoti. “Drug targeting using thermally responsive polymers and local hyperthermia.” J Control Release 74, no. 1–3 (July 6, 2001): 213–24. https://doi.org/10.1016/s0168-3659(01)00319-4.Full Text Link to Item
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Maguire, P. D., T. V. Samulski, L. R. Prosnitz, E. L. Jones, G. L. Rosner, B. Powers, L. W. Layfield, et al. “A phase II trial testing the thermal dose parameter CEM43 degrees T90 as a predictor of response in soft tissue sarcomas treated with pre-operative thermoradiotherapy.” Int J Hyperthermia 17, no. 4 (July 2001): 283–90. https://doi.org/10.1080/02656730110039449.Full Text Link to Item
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Braun, R. D., J. L. Lanzen, S. A. Snyder, and M. W. Dewhirst. “Comparison of tumor and normal tissue oxygen tension measurements using OxyLite or microelectrodes in rodents.” Am J Physiol Heart Circ Physiol 280, no. 6 (June 2001): H2533–44. https://doi.org/10.1152/ajpheart.2001.280.6.H2533.Full Text Link to Item
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Braun, R. D., J. L. Lanzen, J. A. Turnage, G. Rosner, and M. W. Dewhirst. “Effects of the interaction between carbogen and nicotinamide on R3230 Ac tumor blood flow in Fischer 344 rats.” Radiat Res 155, no. 5 (May 2001): 724–33. https://doi.org/10.1667/0033-7587(2001)155[0724:eotibc]2.0.co;2.Full Text Link to Item
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Neeman, M., H. Dafni, O. Bukhari, R. D. Braun, and M. W. Dewhirst. “In vivo BOLD contrast MRI mapping of subcutaneous vascular function and maturation: validation by intravital microscopy.” Magn Reson Med 45, no. 5 (May 2001): 887–98. https://doi.org/10.1002/mrm.1118.Full Text Link to Item
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Lohr, F., D. Y. Lo, D. A. Zaharoff, K. Hu, X. Zhang, Y. Li, Y. Zhao, M. W. Dewhirst, F. Yuan, and C. Y. Li. “Effective tumor therapy with plasmid-encoded cytokines combined with in vivo electroporation.” Cancer Res 61, no. 8 (April 15, 2001): 3281–84.Link to Item
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Connor, C. E., J. D. Norris, G. Broadwater, T. M. Willson, M. M. Gottardis, M. W. Dewhirst, and D. P. McDonnell. “Circumventing tamoxifen resistance in breast cancers using antiestrogens that induce unique conformational changes in the estrogen receptor.” Cancer Res 61, no. 7 (April 1, 2001): 2917–22.Link to Item
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Kong, G., R. D. Braun, and M. W. Dewhirst. “Characterization of the effect of hyperthermia on nanoparticle extravasation from tumor vasculature.” Cancer Res 61, no. 7 (April 1, 2001): 3027–32.Link to Item
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Meyer, D. E., G. A. Kong, M. W. Dewhirst, M. R. Zalutsky, and A. Chilkoti. “Targeting a genetically engineered elastin-like polypeptide to solid tumors by local hyperthermia.” Cancer Res 61, no. 4 (February 15, 2001): 1548–54.Link to Item
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Li, C. Y., J. B. Little, K. Hu, W. Zhang, L. Zhang, M. W. Dewhirst, and Q. Huang. “Persistent genetic instability in cancer cells induced by non-DNA-damaging stress exposures.” Cancer Res 61, no. 2 (January 15, 2001): 428–32.Link to Item
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Neeman, M., J. M. Provenzale, and M. W. Dewhirst. “Magnetic resonance imaging applications in the evaluation of tumor angiogenesis.” Semin Radiat Oncol 11, no. 1 (January 2001): 70–82. https://doi.org/10.1053/srao.2001.18105.Full Text Link to Item
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Pogue, B. W., R. D. Braun, J. L. Lanzen, C. Erickson, and M. W. Dewhirst. “Oxygen microelectrode measurements in R3230Ac tumors during photodynamic therapy with verteporfin.” Proceedings of Spie the International Society for Optical Engineering 4248 (January 1, 2001): 144–49. https://doi.org/10.1117/12.424446.Full Text
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Vujaskovic, Z., I. Batinic-Haberle, I. Spasojevic, I. Fridovich, M. S. Anscher, and M. W. Dewhirst. “Superoxide dismutase (SOD) mimetics in radiation therapy.” Free Radical Biology and Medicine 31 (January 1, 2001): S128–S128.Link to Item
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Kong, G., G. Anyarambhatla, W. P. Petros, R. D. Braun, O. M. Colvin, D. Needham, and M. W. Dewhirst. “Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release.” Cancer Res 60, no. 24 (December 15, 2000): 6950–57.Link to Item
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Haroon, Z. A., K. Amin, J. Hu, C. S. Greenberg, and M. W. Dewhirst. “Inhibition of tyrosine kinase activity by sugen 5416 inhibits fibrin dependent angiogenesis.” Blood 96, no. 11 PART II (December 1, 2000).
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Krol, A., F. Yuan, and M. Dewhirst. “Available volume fraction of macromolecules in solid tumors.” Annals of Biomedical Engineering 28, no. SUPPL. 1 (December 1, 2000).
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Lai, T. S., R. A. Lindberg, A. Hausladen, T. F. Slaughter, Z. A. Haroon, M. W. Dewhirst, J. S. Stamler, and C. S. Greenberg. “Human erythrocyte and endothelial cells contain tbs ce transglutaminase that can regulates inflammation a nd platelet function by binding and releasing nitric oxde.” Blood 96, no. 11 PART I (December 1, 2000).
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Lohr, F., K. Hu, Q. Huang, L. Zhang, T. V. Samulski, M. W. Dewhirst, and C. Y. Li. “Enhancement of radiotherapy by hyperthermia-regulated gene therapy.” Int J Radiat Oncol Biol Phys 48, no. 5 (December 1, 2000): 1513–18. https://doi.org/10.1016/s0360-3016(00)00788-4.Full Text Link to Item
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McGuire, S., X. Y. Zhang, M. Dewhirst, and F. Yuan. “New technique for measurement of distribution volume of color molecules in solid tumors.” Annals of Biomedical Engineering 28, no. SUPPL. 1 (December 1, 2000).
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Yuan, F., D. Zaharoff, X. Y. Zhang, F. Lohr, M. W. Dewhirst, and C. Y. Li. “Delivery of plasmid DNA through intratumoral infusion and electroporation.” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 48 (December 1, 2000): 173–76.
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Zhang, X. Y., J. Luck, M. W. Dewhirst, and F. Yuan. “Interstitial hydraulic conductivity in a fibrosarcoma.” Am J Physiol Heart Circ Physiol 279, no. 6 (December 2000): H2726–34. https://doi.org/10.1152/ajpheart.2000.279.6.H2726.Full Text Link to Item
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Haroon, Z. A., K. Amin, J. Hu, C. S. Greenberg, and M. W. Dewhirst. “Inhibition of tyrosine kinase activity by SUGEN 5416 inhibits fibrin dependent angiogenesis.” Blood 96, no. 11 (November 16, 2000): 57B-57B.Link to Item
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Lai, T. S., R. A. Lindberg, A. Hausladen, T. F. Slaughter, Z. A. Haroon, M. W. Dewhirst, J. S. Stamler, and C. S. Greenberg. “Human erythrocyte and endothelial cells contain tissue transglutaminase that can regulates inflammation and platelet function by binding and releasing nitric oxide.” Blood 96, no. 11 (November 16, 2000): 38A-38A.Link to Item
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Blackwell, K. L., Z. A. Haroon, S. Shan, W. Saito, G. Broadwater, C. S. Greenberg, and M. W. Dewhirst. “Tamoxifen inhibits angiogenesis in estrogen receptor-negative animal models.” Clin Cancer Res 6, no. 11 (November 2000): 4359–64.Link to Item
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Poulson, J. M., M. W. Dewhirst, A. A. Gaskin, Z. Vujaskovic, T. V. Samulski, D. M. Prescott, R. E. Meyer, R. L. Page, and D. E. Thrall. “Acute pancreatitis associated with administration of a nitric oxide synthase inhibitor in tumor-bearing dogs.” In Vivo 14, no. 6 (November 2000): 709–14.Link to Item
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Dewhirst, M. W., B. Klitzman, R. D. Braun, D. M. Brizel, Z. A. Haroon, and T. W. Secomb. “Review of methods used to study oxygen transport at the microcirculatory level.” Int J Cancer 90, no. 5 (October 20, 2000): 237–55.Link to Item
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Hoffman, R. M. “Re: initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models.” J Natl Cancer Inst 92, no. 17 (September 6, 2000): 1445–46. https://doi.org/10.1093/jnci/92.17.1445.Full Text Link to Item
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Li, C. Y., S. Shan, Q. Huang, and M. W. Dewhirst. “RESPONSE: re: initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models.” J Natl Cancer Inst 92, no. 17 (September 6, 2000): 1445–46. https://doi.org/10.1093/jnci/92.17.1445-a.Full Text Link to Item
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Lohr, F., K. Hu, Z. Haroon, T. V. Samulski, Q. Huang, J. Beaty, M. W. Dewhirst, and C. Y. Li. “Combination treatment of murine tumors by adenovirus-mediated local B7/IL12 immunotherapy and radiotherapy.” Mol Ther 2, no. 3 (September 2000): 195–203. https://doi.org/10.1006/mthe.2000.0114.Full Text Link to Item
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Thrall, D. E., G. L. Rosner, C. Azuma, S. M. Larue, B. C. Case, T. Samulski, and M. W. Dewhirst. “Using units of CEM 43 degrees C T90, local hyperthermia thermal dose can be delivered as prescribed.” Int J Hyperthermia 16, no. 5 (September 2000): 415–28. https://doi.org/10.1080/026567300416712.Full Text Link to Item
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Matteucci, M. L., G. Anyarambhatla, G. Rosner, C. Azuma, P. E. Fisher, M. W. Dewhirst, D. Needham, and D. E. Thrall. “Hyperthermia increases accumulation of technetium-99m-labeled liposomes in feline sarcomas.” Clin Cancer Res 6, no. 9 (September 2000): 3748–55.Link to Item
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Kong, G., R. D. Braun, and M. W. Dewhirst. “Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size.” Cancer Res 60, no. 16 (August 15, 2000): 4440–45.Link to Item
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Meyer, R. E., R. D. Braun, G. L. Rosner, and M. W. Dewhirst. “Local 42 degrees C hyperthermia improves vascular conductance of the R3230Ac rat mammary adenocarcinoma during sodium nitroprusside infusion.” Radiat Res 154, no. 2 (August 2000): 196–201. https://doi.org/10.1667/0033-7587(2000)154[0196:lchivc]2.0.co;2.Full Text Link to Item
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Huang, Q., J. K. Hu, F. Lohr, L. Zhang, R. Braun, J. Lanzen, J. B. Little, M. W. Dewhirst, and C. Y. Li. “Heat-induced gene expression as a novel targeted cancer gene therapy strategy.” Cancer Res 60, no. 13 (July 1, 2000): 3435–39.Link to Item
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Meyer, R. E., R. D. Braun, G. L. Rosner, and M. W. Dewhirst. “Nitroprusside improves tumor perfusion during local 42°C hyperthermia.” Vet Anaesth Analg 27, no. 2 (July 2000): 105. https://doi.org/10.1016/S1467-2987(16)31354-X.Full Text Link to Item
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Anscher, M. S., C. Lee, H. Hurwitz, D. Tyler, L. R. Prosnitz, P. Jowell, G. Rosner, T. Samulski, and M. W. Dewhirst. “A pilot study of preoperative continuous infusion 5-fluorouracil, external microwave hyperthermia, and external beam radiotherapy for treatment of locally advanced, unresectable, or recurrent rectal cancer.” Int J Radiat Oncol Biol Phys 47, no. 3 (June 1, 2000): 719–24. https://doi.org/10.1016/s0360-3016(00)00473-9.Full Text Link to Item
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Prescott, D. M., H. C. Charles, J. M. Poulson, R. L. Page, D. E. Thrall, Z. Vujaskovic, and M. W. Dewhirst. “The relationship between intracellular and extracellular pH in spontaneous canine tumors.” Clin Cancer Res 6, no. 6 (June 2000): 2501–5.Link to Item
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Minning, D. M., A. J. Gow, J. Bonaventura, R. Braun, M. Dewhirst, D. E. Goldberg, and J. Stamler. “Ascaris haemoglobin is a nitric oxide-activated "deoxygenase".” Chemtracts 13, no. 5 (May 1, 2000): 320–25.
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Chilkoti, A., D. E. Meyer, G. H. Kong, M. W. Dewhirst, C. Foulon, and M. R. Zalutsky. “Genetically engineered biopolymer conjugate for thermal targeting of anticancer therapeutics.” Abstracts of Papers of the American Chemical Society 219 (March 26, 2000): U453–U453.Link to Item
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Krol, A., S. Nagaraj, M. Dewhirst, and F. Yuan. “Available volume fraction of macromolecules in tumor tissues.” Faseb Journal 14, no. 4 (March 15, 2000): A167–A167.Link to Item
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Meyer, D. E., G. A. Kong, M. W. Dewhirst, C. Foulon, M. R. Zalutsky, and A. Chilkoti. “Genetically engineered polypeptide carrier for thermal targeting of anticancer therapeutics.” American Chemical Society, Polymer Preprints, Division of Polymer Chemistry 41, no. 1 (March 1, 2000): 1020–21.
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Needham, D., G. Anyarambhatla, G. Kong, and M. W. Dewhirst. “A new temperature-sensitive liposome for use with mild hyperthermia: characterization and testing in a human tumor xenograft model.” Cancer Res 60, no. 5 (March 1, 2000): 1197–1201.Link to Item
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Blackwell, K., Z. Haroon, G. Broadwater, D. Berry, L. Harris, J. D. Iglehart, M. Dewhirst, and C. Greenberg. “Plasma D-dimer levels in operable breast cancer patients correlate with clinical stage and axillary lymph node status.” J Clin Oncol 18, no. 3 (February 2000): 600–608. https://doi.org/10.1200/JCO.2000.18.3.600.Full Text Link to Item
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Li, C. Y., S. Shan, Q. Huang, R. D. Braun, J. Lanzen, K. Hu, P. Lin, and M. W. Dewhirst. “Initial stages of tumor cell-induced angiogenesis: evaluation via skin window chambers in rodent models.” J Natl Cancer Inst 92, no. 2 (January 19, 2000): 143–47. https://doi.org/10.1093/jnci/92.2.143.Full Text Link to Item
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Adams, D. J., M. W. Dewhirst, J. L. Flowers, M. P. Gamcsik, O. M. Colvin, G. Manikumar, M. C. Wani, and M. E. Wall. “Camptothecin analogues with enhanced antitumor activity at acidic pH.” Cancer Chemother Pharmacol 46, no. 4 (2000): 263–71. https://doi.org/10.1007/s002800000157.Full Text Link to Item
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Haroon, Z. A., J. A. Raleigh, C. S. Greenberg, and M. W. Dewhirst. “Early wound healing exhibits cytokine surge without evidence of hypoxia.” Ann Surg 231, no. 1 (January 2000): 137–47. https://doi.org/10.1097/00000658-200001000-00020.Full Text Link to Item
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Klitzman, B., R. D. Braun, A. C. Lockhart, L. Heller, M. W. Dewhirst, and H. I. Hurwitz. “Wound-induced angiogenesis: A clinical model.” Edited by K. Messmer. Orthogonal Polarization Spectral Imaging 24 (January 1, 2000): 110–14.Link to Item
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Li, C. Y., S. Shan, Y. Cao, and M. W. Dewhirst. “Role of incipient angiogenesis in cancer metastasis.” Cancer Metastasis Rev 19, no. 1–2 (2000): 7–11. https://doi.org/10.1023/a:1026538601947.Full Text Link to Item
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Vujaskovic, Z., J. M. Poulson, A. A. Gaskin, D. E. Thrall, R. L. Page, H. C. Charles, J. R. MacFall, et al. “Temperature-dependent changes in physiologic parameters of spontaneous canine soft tissue sarcomas after combined radiotherapy and hyperthermia treatment.” Int J Radiat Oncol Biol Phys 46, no. 1 (January 1, 2000): 179–85. https://doi.org/10.1016/s0360-3016(99)00362-4.Full Text Link to Item
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Dewhirst, M. “Boris Pasternak: A literary biography, vol 2, 1928-1960.” Europe Asia Studies 51, no. 8 (December 1, 1999): 1505–6.Link to Item
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Haroon, Z. A., T. S. Lai, J. M. Hettasch, R. A. Lindberg, M. W. Dewhirst, and C. S. Greenberg. “Tissue transglutaminase is expressed as a host response to tumor invasion and inhibits tumor growth.” Lab Invest 79, no. 12 (December 1999): 1679–86.Link to Item
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Meyer, D. E., G. Kong, M. Dewhirst, and A. Chilkoti. “Genetically-engineered polypeptide carrier for thermal targeting of therapeutics.” Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings 2 (December 1, 1999): 1289.
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Craciunescu, O., S. K. Das, and M. W. Dewhirst. “Three-dimensional microvascular networks fractal structure: potential for tissue characterization?” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 44 (December 1, 1999): 9–13.
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Secomb, T. W., R. Hsu, R. D. Braun, and M. W. Dewhirst. “Analysis of oxygen transport to tumors: causes of heterogeneous tissue oxygenation.” American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed 42 (December 1, 1999): 487–88.
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Brizel, D. M., R. K. Dodge, R. W. Clough, and M. W. Dewhirst. “Oxygenation of head and neck cancer: changes during radiotherapy and impact on treatment outcome.” Radiother Oncol 53, no. 2 (November 1999): 113–17. https://doi.org/10.1016/s0167-8140(99)00102-4.Full Text Link to Item
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Larue, S. M., M. H. Fox, G. K. Ogilvie, R. L. Page, D. M. Getzy, D. E. Thrall, J. L. Johnson, M. W. Dewhirst, and E. L. Gillette. “Tumour cell kinetics as predictors of response in canine lymphoma treated with chemotherapy alone or combined with whole body hyperthermia.” Int J Hyperthermia 15, no. 6 (November 1999): 475–86. https://doi.org/10.1080/026567399285477.Full Text Link to Item
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Prosnitz, L. R., P. Maguire, J. M. Anderson, S. P. Scully, J. M. Harrelson, E. L. Jones, M. Dewhirst, et al. “The treatment of high-grade soft tissue sarcomas with preoperative thermoradiotherapy.” Int J Radiat Oncol Biol Phys 45, no. 4 (November 1, 1999): 941–49. https://doi.org/10.1016/s0360-3016(99)00272-2.Full Text Link to Item
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Huang, Q., S. Shan, R. D. Braun, J. Lanzen, G. Anyrhambatla, G. Kong, M. Borelli, P. Corry, M. W. Dewhirst, and C. Y. Li. “Noninvasive visualization of tumors in rodent dorsal skin window chambers.” Nat Biotechnol 17, no. 10 (October 1999): 1033–35. https://doi.org/10.1038/13736.Full Text Link to Item
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Haroon, Z. A., J. M. Hettasch, T. S. Lai, M. W. Dewhirst, and C. S. Greenberg. “Tissue transglutaminase is expressed, active, and directly involved in rat dermal wound healing and angiogenesis.” Faseb J 13, no. 13 (October 1999): 1787–95. https://doi.org/10.1096/fasebj.13.13.1787.Full Text Link to Item
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Minning, D. M., A. J. Gow, J. Bonaventura, R. Braun, M. Dewhirst, D. E. Goldberg, and J. S. Stamler. “Ascaris haemoglobin is a nitric oxide-activated 'deoxygenase'.” Nature 401, no. 6752 (September 30, 1999): 497–502. https://doi.org/10.1038/46822.Full Text Link to Item
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Kong, G., and M. W. Dewhirst. “Hyperthermia and liposomes.” Int J Hyperthermia 15, no. 5 (September 1999): 345–70. https://doi.org/10.1080/026567399285558.Full Text Link to Item
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Thrall, D. E., S. M. Larue, B. E. Powers, R. L. Page, J. Johnson, S. L. George, J. N. Kornegay, et al. “Use of whole body hyperthermia as a method to heat inaccessible tumours uniformly: a phase III trial in canine brain masses.” Int J Hyperthermia 15, no. 5 (September 1999): 383–98. https://doi.org/10.1080/026567399285576.Full Text Link to Item
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Krol, A., J. Maresca, M. W. Dewhirst, and F. Yuan. “Available volume fraction of macromolecules in the extravascular space of a fibrosarcoma: implications for drug delivery.” Cancer Res 59, no. 16 (August 15, 1999): 4136–41.Link to Item
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Braun, R. D., J. L. Lanzen, and M. W. Dewhirst. “Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats.” Am J Physiol 277, no. 2 (August 1999): H551–68. https://doi.org/10.1152/ajpheart.1999.277.2.H551.Full Text Link to Item
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Braun, R. D., J. L. Lanzen, and M. W. Dewhirst. “Fourier analysis of fluctuations of oxygen tension and blood flow in R3230Ac tumors and muscle in rats.” American Journal of Physiology Heart and Circulatory Physiology 277, no. 2 (August 1, 1999): H551–68.Link to Item
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Haroon, Z. A., J. A. Raleigh, C. S. Greenberg, and M. W. Dewhirst. “Early wound healing exhibits pro-angiogenic cytokine surge without evidence of hypoxia.” Faseb Journal 13, no. 7 (April 23, 1999): A1512–A1512.Link to Item
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Dewhirst, M. W., E. T. Ong, R. D. Braun, B. Smith, B. Klitzman, S. M. Evans, and D. Wilson. “Quantification of longitudinal tissue pO2 gradients in window chamber tumours: impact on tumour hypoxia.” Br J Cancer 79, no. 11–12 (April 1999): 1717–22. https://doi.org/10.1038/sj.bjc.6690273.Full Text Link to Item
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Dunn, T. J., R. D. Braun, W. E. Rhemus, G. L. Rosner, T. W. Secomb, G. M. Tozer, D. J. Chaplin, and M. W. Dewhirst. “The effects of hyperoxic and hypercarbic gases on tumour blood flow.” Br J Cancer 80, no. 1–2 (April 1999): 117–26. https://doi.org/10.1038/sj.bjc.6690330.Full Text Link to Item
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Hettasch, J. M., R. A. Lindberg, T. S. Lai, M. W. Dewhirst, and C. S. Greenberg. “Nitric oxide modulates extracellular matrix stabilization by inhibiting endothelial cell transglutaminase activity.” Blood 92, no. 10 (November 15, 1998): 77B-77B.Link to Item
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Biaglow, J. E., Y. Manevich, D. Leeper, B. Chance, M. W. Dewhirst, W. T. Jenkins, S. W. Tuttle, et al. “MIBG inhibits respiration: potential for radio- and hyperthermic sensitization.” Int J Radiat Oncol Biol Phys 42, no. 4 (November 1, 1998): 871–76. https://doi.org/10.1016/s0360-3016(98)00334-4.Full Text Link to Item
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Dewhirst, M. W., R. D. Braun, and J. L. Lanzen. “Temporal changes in PO2 of R3230AC tumors in Fischer-344 rats.” Int J Radiat Oncol Biol Phys 42, no. 4 (November 1, 1998): 723–26. https://doi.org/10.1016/s0360-3016(98)00304-6.Full Text Link to Item
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Lanzen, J. L., R. D. Braun, A. L. Ong, and M. W. Dewhirst. “Variability in blood flow and pO2 in tumors in response to carbogen breathing.” Int J Radiat Oncol Biol Phys 42, no. 4 (November 1, 1998): 855–59. https://doi.org/10.1016/s0360-3016(98)00312-5.Full Text Link to Item
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Peters, K. G., C. Lin, A. Acheson, C. Redziejewski, P. Maisonpierre, G. D. Yancopoulos, M. W. Dewhirst, et al. “Role of Tie2 in pathologic angiogenesis.” Journal of Vascular Research 35, no. 5 (September 1, 1998): 373–373.Link to Item
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Lin, P., J. A. Buxton, A. Acheson, C. Radziejewski, P. C. Maisonpierre, G. D. Yancopoulos, K. M. Channon, et al. “Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2.” Proc Natl Acad Sci U S A 95, no. 15 (July 21, 1998): 8829–34. https://doi.org/10.1073/pnas.95.15.8829.Full Text Link to Item
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Dewhirst, M. W. “Concepts of oxygen transport at the microcirculatory level.” Semin Radiat Oncol 8, no. 3 (July 1998): 143–50. https://doi.org/10.1016/s1053-4296(98)80040-4.Full Text Link to Item
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Dewhirst, M. W., and J. B. Mitchell. “Introduction.” Semin Radiat Oncol 8, no. 3 (July 1998): 141–42. https://doi.org/10.1016/s1053-4296(98)80039-8.Full Text Link to Item
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Bryce, T. J., M. W. Dewhirst, C. E. Floyd, V. Hars, and D. M. Brizel. “Artificial neural network model of survival in patients treated with irradiation with and without concurrent chemotherapy for advanced carcinoma of the head and neck.” Int J Radiat Oncol Biol Phys 41, no. 2 (May 1, 1998): 339–45. https://doi.org/10.1016/s0360-3016(98)00016-9.Full Text Link to Item
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Dewhirst, M. W., and P. M. Corry. “Further justification for development of non-invasive thermometry.” Int J Hyperthermia 14, no. 3 (May 1998): 255. https://doi.org/10.3109/02656739809018230.Full Text Link to Item
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Secomb, T. W., R. Hsu, R. D. Braun, J. R. Ross, J. F. Gross, and M. W. Dewhirst. “Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels.” Journal of Vascular Research 35, no. 3 (May 1, 1998): 229–30.Link to Item
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Wink, D. A., Y. Vodovotz, J. Laval, F. Laval, M. W. Dewhirst, and J. B. Mitchell. “The multifaceted roles of nitric oxide in cancer.” Carcinogenesis 19, no. 5 (May 1998): 711–21. https://doi.org/10.1093/carcin/19.5.711.Full Text Link to Item
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Acker, J. C., L. B. Marks, D. P. Spencer, W. Yang, M. A. Avery, R. K. Dodge, G. L. Rosner, and M. W. Dewhirst. “Serial in vivo observations of cerebral vasculature after treatment with a large single fraction of radiation.” Radiat Res 149, no. 4 (April 1998): 350–59.Link to Item
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Sneed, P. K., M. W. Dewhirst, T. Samulski, J. Blivin, and L. R. Prosnitz. “Should interstitial thermometry be used for deep hyperthermia?” Int J Radiat Oncol Biol Phys 40, no. 5 (March 15, 1998): 1015–17. https://doi.org/10.1016/s0360-3016(98)00007-8.Full Text Link to Item
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Lin, P., S. Sankar, S. Shan, M. W. Dewhirst, P. J. Polverini, T. Q. Quinn, and K. G. Peters. “Inhibition of tumor growth by targeting tumor endothelium using a soluble vascular endothelial growth factor receptor.” Cell Growth Differ 9, no. 1 (January 1998): 49–58.Link to Item
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Secomb, T. W., R. Hsu, R. D. Braun, J. R. Ross, J. F. Gross, and M. W. Dewhirst. “Theoretical simulation of oxygen transport to tumors by three-dimensional networks of microvessels.” Adv Exp Med Biol 454 (1998): 629–34. https://doi.org/10.1007/978-1-4615-4863-8_74.Full Text Link to Item
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Tozer, G. M., V. E. Prise, J. Wilson, B. Vojnovic, S. Q. Shan, M. W. Dewhirst, and D. J. Chaplin. “Combretastatin A-4 P as a tumour vascular targeting agent.” British Journal of Cancer 78 (January 1, 1998): 48–48.Link to Item
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Wilson, D. F., S. M. Evans, W. T. Jenkins, S. A. Vinogradov, E. Ong, and M. W. Dewhirst. “Oxygen distributions within R3230Ac tumors growing in dorsal flap window chambers in rats.” Adv Exp Med Biol 454 (1998): 603–9. https://doi.org/10.1007/978-1-4615-4863-8_71.Full Text Link to Item
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Dewhirst, M. W., L. Prosnitz, D. Thrall, D. Prescott, S. Clegg, C. Charles, J. MacFall, et al. “Hyperthermic treatment of malignant diseases: current status and a view toward the future.” Semin Oncol 24, no. 6 (December 1997): 616–25.Link to Item
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Lindberg, R. A., B. Haribabu, R. Syal, R. Snyderman, and M. W. Dewhirst. “L-selectin-dependent leukocyte rolling on endothelial monolayers under flow.” Faseb Journal 11, no. 3 (December 1, 1997).
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Haroon, Z. A., J. M. Hettasch, M. W. Dewhirst, and C. S. Greenberg. “The transglutaminase enzyme derived from vascular cells contributes to the proangiogenic properties of fibrin.” Blood 90, no. 10 (November 15, 1997): 3043–3043.Link to Item
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Brizel, David M., and Mark W. Dewhirst. “Response to the Letter of Drs. Hartmann et al.” Radiation Research 148, no. 5 (November 1997): 524–524. https://doi.org/10.2307/3579328.Full Text
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Bryce, T. J., M. W. Dewhirst, C. E. Floyd, V. Hars, and D. M. Brizel. “An artificial neural network predictive model of survival in patients treated for advanced carcinoma of the head and neck.” Radiology 205 (November 1, 1997): 1419–1419.Link to Item
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Hartmann, K. A., A. J. Van der Kleij, C. J. Schneider, and P. Sminia. “Is hyperbaric oxygen more effective than carbogen/nicotinamide in tumor radiation response?” Radiat Res 148, no. 5 (November 1997): 523–25.Link to Item
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Lin, P., P. Polverini, M. Dewhirst, S. Shan, P. S. Rao, and K. Peters. “Inhibition of tumor angiogenesis using a soluble receptor establishes a role for Tie2 in pathologic vascular growth.” J Clin Invest 100, no. 8 (October 15, 1997): 2072–78. https://doi.org/10.1172/JCI119740.Full Text Link to Item
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Wong, A. L., Z. A. Haroon, S. Werner, M. W. Dewhirst, C. S. Greenberg, and K. G. Peters. “Tie2 expression and phosphorylation in angiogenic and quiescent adult tissues.” Circ Res 81, no. 4 (October 1997): 567–74. https://doi.org/10.1161/01.res.81.4.567.Full Text Link to Item
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Nozue, M., I. Lee, F. Yuan, B. A. Teicher, D. M. Brizel, M. W. Dewhirst, C. G. Milross, et al. “Interlaboratory variation in oxygen tension measurement by Eppendorf "Histograph" and comparison with hypoxic marker.” J Surg Oncol 66, no. 1 (September 1997): 30–38. https://doi.org/10.1002/(sici)1096-9098(199709)66:1<30::aid-jso7>3.0.co;2-o.Full Text Link to Item
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Brizel, D. M., W. D. Hage, R. K. Dodge, M. T. Munley, C. A. Piantadosi, and M. W. Dewhirst. “Hyperbaric oxygen improves tumor radiation response significantly more than carbogen/nicotinamide.” Radiat Res 147, no. 6 (June 1997): 715–20.Link to Item
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Brizel, D. M., G. S. Sibley, L. R. Prosnitz, R. L. Scher, and M. W. Dewhirst. “Tumor hypoxia adversely affects the prognosis of carcinoma of the head and neck.” Int J Radiat Oncol Biol Phys 38, no. 2 (May 1, 1997): 285–89. https://doi.org/10.1016/s0360-3016(97)00101-6.Full Text Link to Item
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Hauck, M. L., D. O. Coffin, R. K. Dodge, M. W. Dewhirst, J. B. Mitchell, and M. R. Zalutsky. “A local hyperthermia treatment which enhances antibody uptake in a glioma xenograft model does not affect tumour interstitial fluid pressure.” Int J Hyperthermia 13, no. 3 (May 1997): 307–16. https://doi.org/10.3109/02656739709023538.Full Text Link to Item
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Anscher, M. S., T. V. Samulski, R. Dodge, L. R. Prosnitz, and M. W. Dewhirst. “Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostate.” Int J Radiat Oncol Biol Phys 37, no. 5 (March 15, 1997): 1059–65. https://doi.org/10.1016/s0360-3016(97)00109-0.Full Text Link to Item
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Braun, R. D., M. W. Dewhirst, and D. L. Hatchell. “Quantification of erythrocyte flow in the choroid of the albino rat.” Am J Physiol 272, no. 3 Pt 2 (March 1997): H1444–53. https://doi.org/10.1152/ajpheart.1997.272.3.H1444.Full Text Link to Item
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Braun, R. D., M. W. Dewhirst, and D. L. Hatchell. “Quantification of erythrocyte flow in the choroid of the albino rat.” American Journal of Physiology Heart and Circulatory Physiology 272, no. 3 (March 1, 1997): H1444–53.Link to Item
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Wu, N. Z., R. D. Braun, M. H. Gaber, G. M. Lin, E. T. Ong, S. Shan, D. Papahadjopoulos, and M. W. Dewhirst. “Simultaneous measurement of liposome extravasation and content release in tumors.” Microcirculation 4, no. 1 (March 1997): 83–101. https://doi.org/10.3109/10739689709148320.Full Text Link to Item
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Lindberg, R. A., B. Haribabu, R. Syal, R. Snyderman, and M. W. Dewhirst. “L-selectin-dependent leukocyte rolling on endothelial monolayers under flow.” Faseb Journal 11, no. 3 (February 28, 1997): 1752–1752.Link to Item
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Hahn, J. S., R. D. Braun, M. W. Dewhirst, S. Shan, S. A. Snyder, J. M. Taube, E. T. Ong, et al. “Stroma-free human hemoglobin A decreases R3230Ac rat mammary adenocarcinoma blood flow and oxygen partial pressure.” Radiat Res 147, no. 2 (February 1997): 185–94.Link to Item
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Bean, J. M., G. E. Archer, M. T. Munley, E. Ong, S. A. Snyder, Z. A. Haroon, R. E. McLendon, et al. “2013 The impact of hypoxia and oxygenation modification on the radiation response of an intracranial rat glioma.” International Journal of Radiation Oncology*Biology*Physics 39, no. 2 (January 1997): 247–247. https://doi.org/10.1016/s0360-3016(97)80782-1.Full Text
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Dewhirst, Mark W., Edgardo T. Ong, Rod D. Braun, Sydney M. Evans, and David Wilson. “152 Identification of longitudinal tissue pO2 gradients as one cause for vascular hypoxia in window chamber tumors.” International Journal of Radiation Oncology*Biology*Physics 39, no. 2 (January 1997): 211–211. https://doi.org/10.1016/s0360-3016(97)80710-9.Full Text
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Shan, S. Q., G. L. Rosner, R. D. Braun, J. Hahn, C. Pearce, and M. W. Dewhirst. “Effects of diethylamine/nitric oxide on blood perfusion and oxygenation in the R3230Ac mammary carcinoma.” Br J Cancer 76, no. 4 (1997): 429–37. https://doi.org/10.1038/bjc.1997.406.Full Text Link to Item
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Hauck, M. L., M. W. Dewhirst, D. D. Bigner, and M. R. Zalutsky. “Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model.” Clin Cancer Res 3, no. 1 (January 1997): 63–70.Link to Item
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Brizel, D. M., S. P. Scully, J. M. Harrelson, L. J. Layfield, R. K. Dodge, H. C. Charles, T. V. Samulski, L. R. Prosnitz, and M. W. Dewhirst. “Radiation therapy and hyperthermia improve the oxygenation of human soft tissue sarcomas.” Cancer Res 56, no. 23 (December 1, 1996): 5347–50.Link to Item
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Dewhirst, M. W. “Abstract of the Thirty-Ninth Annual Meeting of the Japan Radiation Research Society, Osaka, November 18-20, 1996, with author index.” Journal of Radiation Research 37, no. 4 (December 1, 1996): 278–408.Link to Item
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Dewhirst, M. “The politics of religion in Russia and the new states of Eurasia, the international politics of Eurasia, vol 3 - Bourdeaux,M.” Europe Asia Studies 48, no. 8 (December 1, 1996): 1448–49.Link to Item
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Gaber, M. H., N. Z. Wu, K. Hong, S. K. Huang, M. W. Dewhirst, and D. Papahadjopoulos. “Thermosensitive liposomes: extravasation and release of contents in tumor microvascular networks.” Int J Radiat Oncol Biol Phys 36, no. 5 (December 1, 1996): 1177–87. https://doi.org/10.1016/s0360-3016(96)00389-6.Full Text Link to Item
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Haroon, Z. A., R. L. McCauley, J. M. Hettasch, T. S. Lai, R. Lindberg, K. Peters, M. W. Dewhirst, and C. S. Greenberg. “Recombinant human tissue transglutaminase modifies angiogenesis and delays mammary tumor growth in vivo.” Faseb Journal 10, no. 6 (December 1, 1996).
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Kimura, H., R. D. Braun, E. T. Ong, R. Hsu, T. W. Secomb, D. Papahadjopoulos, K. Hong, and M. W. Dewhirst. “Fluctuations in red cell flux in tumor microvessels can lead to transient hypoxia and reoxygenation in tumor parenchyma.” Cancer Res 56, no. 23 (December 1, 1996): 5522–28.Link to Item
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Lindberg, R. A., M. W. Dewhirst, B. J. Buckley, C. S. Hughes, and A. Richard Whorton. “Ca2+-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells.” American Journal of Physiology 271, no. 1 PART 1 (December 1, 1996).
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Thrall, D. E., T. V. Samulski, M. W. Dewhirst, and D. M. Prescott. “Re: Kapp editorial IJROBP 35:189-194; 1996.” Int J Radiat Oncol Biol Phys 36, no. 4 (November 1, 1996): 989. https://doi.org/10.1016/s0360-3016(97)89875-6.Full Text Link to Item
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Hettasch, J. M., N. Bandarenko, J. L. Burchette, T. S. Lai, J. R. Marks, Z. A. Haroon, K. Peters, M. W. Dewhirst, J. D. Iglehart, and C. S. Greenberg. “Tissue transglutaminase expression in human breast cancer.” Lab Invest 75, no. 5 (November 1996): 637–45.Link to Item
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Jones, D. N., G. B. McCowage, H. D. Sostman, D. M. Brizel, L. Layfield, H. C. Charles, M. W. Dewhirst, et al. “Monitoring of neoadjuvant therapy response of soft-tissue and musculoskeletal sarcoma using fluorine-18-FDG PET.” J Nucl Med 37, no. 9 (September 1996): 1438–44.Link to Item
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Dewhirst, M. W., E. T. Ong, G. L. Rosner, S. W. Rehmus, S. Shan, R. D. Braun, D. M. Brizel, and T. W. Secomb. “Arteriolar oxygenation in tumour and subcutaneous arterioles: effects of inspired air oxygen content.” Br J Cancer Suppl 27 (July 1996): S241–46.Link to Item
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Dewhirst, M. W., H. Kimura, S. W. Rehmus, R. D. Braun, D. Papahadjopoulos, K. Hong, and T. W. Secomb. “Microvascular studies on the origins of perfusion-limited hypoxia.” Br J Cancer Suppl 27 (July 1996): S247–51.Link to Item
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Dewhirst, Martin. “Modern tsars and princes: the struggle for hegemony in Russia.” International Affairs 72, no. 3 (July 1996): 619–619. https://doi.org/10.2307/2625639.Full Text
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Lindberg, R. A., M. W. Dewhirst, B. J. Buckley, C. S. Hughes, and A. R. Whorton. “Ca(2+)-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells.” Am J Physiol 271, no. 1 Pt 1 (July 1996): C332–37. https://doi.org/10.1152/ajpcell.1996.271.1.C332.Full Text Link to Item
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Lindberg, R. A., M. W. Dewhirst, B. J. Buckley, C. S. Hughes, and A. R. Whorton. “Ca2+-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells.” American Journal of Physiology Cell Physiology 271, no. 1 (July 1, 1996): C332–37.Link to Item
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Hauck, M. L., G. S. Price, G. K. Ogilvie, J. Johnson, E. L. Gillette, D. E. Thrall, M. W. Dewhirst, and R. L. Page. “Phase I evaluation of mitoxantrone alone and combined with whole body hyperthermia in dogs with lymphoma.” Int J Hyperthermia 12, no. 3 (May 1996): 309–20. https://doi.org/10.3109/02656739609022520.Full Text Link to Item
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Hauck, M. L., M. W. Dewhirst, and M. R. Zalutsky. “The effects of clinically relevant hyperthermic temperatures on the kinetic binding parameters of a monoclonal antibody.” Nucl Med Biol 23, no. 4 (May 1996): 551–57. https://doi.org/10.1016/0969-8051(96)00039-x.Full Text Link to Item
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Haroon, Z. A., R. L. McCauley, J. M. Hettasch, T. S. Lai, R. Lindberg, K. Peters, M. W. Dewhirst, and C. S. Greenberg. “Recombinant human tissue transglutaminase modifies angiogenesis and delays mammary tumor growth in vivo.” Faseb Journal 10, no. 6 (April 30, 1996): 2403–2403.Link to Item
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Hettasch, J. M., Z. Haroon, M. W. Dewhirst, J. Marks, D. Iglehart, K. Peters, and C. S. Greenberg. “Tissue transglutaminase is associated with the neovasculature and extracellular matrix of human breast cancer.” Faseb Journal 10, no. 6 (April 30, 1996): 2402–2402.Link to Item
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Thrall, D. E., D. M. Prescott, T. V. Samulski, G. L. Rosner, D. L. Denman, R. L. Legorreta, R. K. Dodge, et al. “Radiation plus local hyperthermia versus radiation plus the combination of local and whole-body hyperthermia in canine sarcomas.” Int J Radiat Oncol Biol Phys 34, no. 5 (March 15, 1996): 1087–96. https://doi.org/10.1016/0360-3016(95)02260-0.Full Text Link to Item
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Brizel, D. M., S. P. Scully, J. M. Harrelson, L. J. Layfield, J. M. Bean, L. R. Prosnitz, and M. W. Dewhirst. “Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma.” Cancer Res 56, no. 5 (March 1, 1996): 941–43.Link to Item
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Gulledge, C. J., and M. W. Dewhirst. “Tumor oxygenation: a matter of supply and demand.” Anticancer Res 16, no. 2 (March 1996): 741–49.Link to Item
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Rosner, G. L., S. T. Clegg, D. M. Prescott, and M. W. Dewhirst. “Estimation of cell survival in tumours heated to nonuniform temperature distributions.” Int J Hyperthermia 12, no. 2 (March 1996): 303–4. https://doi.org/10.3109/02656739609022518.Full Text Link to Item
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Rosner, G. L., S. T. Clegg, D. M. Prescott, and M. W. Dewhirst. “Estimation of cell survival in tumours heated to nonuniform temperature distributions.” Int J Hyperthermia 12, no. 2 (March 1996): 223–39. https://doi.org/10.3109/02656739609022511.Full Text Link to Item
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Braun, R. D., M. W. Dewhirst, D. Papahadjopoulos, and D. L. Hatchell. “Observation and quantification of erythrocyte flow in the choroid of the albino rat.” Investigative Ophthalmology and Visual Science 37, no. 3 (February 15, 1996).
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Braun, R. D., M. W. Dewhirst, D. Papahadjopoulos, and D. L. Hatchell. “Observation and quantification of erythrocyte flow in the choroid of the albino rat.” Investigative Ophthalmology & Visual Science 37, no. 3 (February 15, 1996): 4422–4422.Link to Item
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Dewhirst, M. W. “Editorial Comment.” International Journal of Hyperthermia 12, no. 2 (January 1996): 209–10. https://doi.org/10.3109/02656739609022509.Full Text
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Dewhirst, M. W., E. T. Ong, G. L. Rosner, S. W. Rehmus, S. Shan, R. D. Braun, D. M. Brizel, and T. W. Secomb. “Arteriolar oxygenation in tumour and subcutaneous arterioles: Effects of inspired air oxygen content.” British Journal of Cancer 74, no. SUPPL. XXVII (January 1, 1996).
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Dewhirst, M. W., H. Kimura, S. Rehmus, R. D. Braun, D. Papahadjopoulos, K. Hong, and T. W. Secomb. “Microvascular studies on the origins of perfusion-limited hypoxia.” British Journal of Cancer 74, no. SUPPL. XXVII (January 1, 1996).
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Field, S. B., M. W. Dewhirst, J. Overgaard, and T. Sugahara. “Editorial.” International Journal of Hyperthermia 12, no. 1 (January 1996): 1–2. https://doi.org/10.3109/02656739609023684.Full Text
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Lindberg, R. A., M. W. Dewhirst, B. J. Buckley, C. S. Hughes, and A. R. Whorton. “Ca2+-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells.” American Journal of Physiology Cell Physiology 271, no. 1 40-1 (1996): C332–37.
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Lindberg, R. A., M. W. Dewhirst, B. J. Buckley, C. S. Hughes, and A. R. Whorton. “Ca2+-dependent nitric oxide release in endothelial but not R3230Ac rat mammary adenocarcinoma cells.” American Journal of Physiology 271, no. 1 PART 1 (1996): C338–46.
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Raleigh, J. A., M. W. Dewhirst, and D. E. Thrall. “Measuring Tumor Hypoxia.” Semin Radiat Oncol 6, no. 1 (January 1996): 37–45. https://doi.org/10.1053/SRAO0060037.Full Text Link to Item
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Zalutsky, M. R., J. M. Schuster, P. K. Garg, G. E. Archer, M. W. Dewhirst, and D. D. Bigner. “Two approaches for enhancing radioimmunotherapy: alpha emitters and hyperthermia.” Recent Results Cancer Res 141 (1996): 101–22. https://doi.org/10.1007/978-3-642-79952-5_7.Full Text Link to Item
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Brizel, D. M., S. Lin, J. L. Johnson, J. Brooks, M. W. Dewhirst, and C. A. Piantadosi. “The mechanisms by which hyperbaric oxygen and carbogen improve tumour oxygenation.” Br J Cancer 72, no. 5 (November 1995): 1120–24. https://doi.org/10.1038/bjc.1995.474.Full Text Link to Item
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Prosnitz, L. R., and M. W. Dewhirst. “Progress toward a thermal dosimetry system.” Int J Radiat Oncol Biol Phys 33, no. 4 (November 1, 1995): 963–64. https://doi.org/10.1016/0360-3016(95)02143-2.Full Text Link to Item
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Kimura, H., N. Z. Wu, R. Dodge, D. P. Spencer, B. M. Klitzman, T. M. McIntyre, and M. W. Dewhirst. “Inhibition of radiation-induced up-regulation of leukocyte adhesion to endothelial cells with the platelet-activating factor inhibitor, BN52021.” Int J Radiat Oncol Biol Phys 33, no. 3 (October 15, 1995): 627–33. https://doi.org/10.1016/0360-3016(95)00205-D.Full Text Link to Item
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Dewhirst, Martin. “The legacy of history in Russia and the new states of Eurasia.” International Affairs 71, no. 4 (October 1995): 893–94. https://doi.org/10.2307/2625189.Full Text
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Dewhirst, M. W., S. M. LaRue, and L. Gerweck. “Tumor physiology and cell kinetics.” Semin Vet Med Surg Small Anim 10, no. 3 (August 1995): 148–57.Link to Item
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Brizel, D. M., G. L. Rosner, L. R. Prosnitz, and M. W. Dewhirst. “Patterns and variability of tumor oxygenation in human soft tissue sarcomas, cervical carcinomas, and lymph node metastases.” Int J Radiat Oncol Biol Phys 32, no. 4 (July 15, 1995): 1121–25. https://doi.org/10.1016/0360-3016(95)00106-9.Full Text Link to Item
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Page, R. L., J. Lee, J. E. Riviere, R. K. Dodge, D. E. Thrall, and M. W. Dewhirst. “Absence of whole body hyperthermia effect on cisplatin distribution in spontaneous canine tumors.” Int J Radiat Oncol Biol Phys 32, no. 4 (July 15, 1995): 1097–1102. https://doi.org/10.1016/0360-3016(94)00483-2.Full Text Link to Item
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Castellino, S. M., H. S. Friedman, G. B. Elion, E. T. Ong, S. L. Marcelli, R. Page, D. D. Bigner, and M. W. Dewhirst. “Flunarizine enhancement of melphalan activity against drug-sensitive/resistant rhabdomyosarcoma.” Br J Cancer 71, no. 6 (June 1995): 1181–87. https://doi.org/10.1038/bjc.1995.230.Full Text Link to Item
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Meyer, R. E., S. Shan, J. DeAngelo, R. K. Dodge, J. Bonaventura, E. T. Ong, and M. W. Dewhirst. “Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma.” Br J Cancer 71, no. 6 (June 1995): 1169–74. https://doi.org/10.1038/bjc.1995.228.Full Text Link to Item
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Foltz, R. M., R. E. McLendon, H. S. Friedman, R. K. Dodge, D. D. Bigner, and M. W. Dewhirst. “A pial window model for the intracranial study of human glioma microvascular function.” Neurosurgery 36, no. 5 (May 1995): 976–84. https://doi.org/10.1227/00006123-199505000-00014.Full Text Link to Item
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LINDBERG, R. A., M. W. DEWHIRST, B. J. BUCKLEY, and A. R. WHORTON. “CALCIUM-DEPENDENT NITRIC-OXIDE RELEASE IN ENDOTHELIAL-CELLS BUT NOT IN RAT MAMMARY ADENOCARCINOMA CELLS.” Faseb Journal 9, no. 3 (March 9, 1995): A29–A29.Link to Item
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Meyer, R. E., S. Shan, J. DeAngelo, R. K. Dodge, J. Bonaventura, E. T. Ong, and M. W. Dewhirst. “Nitric oxide synthase inhibition irreversibly decreases perfusion in the R3230Ac rat mammary adenocarcinoma.” British Journal of Cancer 71, no. 6 (January 1, 1995): 1169–74. https://doi.org/10.1038/bjc.1995.228.Full Text
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Secomb, T. W., R. Hsu, E. T. Ong, J. F. Gross, and M. W. Dewhirst. “Analysis of the effects of oxygen supply and demand on hypoxic fraction in tumors.” Acta Oncol 34, no. 3 (1995): 313–16. https://doi.org/10.3109/02841869509093981.Full Text Link to Item
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Schuster, J. M., M. R. Zalutsky, M. A. Noska, R. Dodge, H. S. Friedman, D. D. Bigner, and M. W. Dewhirst. “Hyperthermic modulation of radiolabelled antibody uptake in a human glioma xenograft and normal tissues.” Int J Hyperthermia 11, no. 1 (January 1995): 59–72. https://doi.org/10.3109/02656739509004948.Full Text Link to Item
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Brizel, D. M., R. Dodge, and M. W. Dewhirst. “The effect of the perflubron emulsion Oxygent on the calibration characteristics of polarographic oxygen electrodes.” Radiother Oncol 33, no. 3 (December 1994): 262–65. https://doi.org/10.1016/0167-8140(94)90362-x.Full Text Link to Item
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Page, R. L., M. C. McEntee, P. L. Williams, S. L. George, G. S. Price, C. A. Novotney, M. L. Hauck, J. E. Riviere, M. W. Dewhirst, and D. E. Thrall. “Effect of whole body hyperthermia on carboplatin disposition and toxicity in dogs.” Int J Hyperthermia 10, no. 6 (November 1994): 807–16. https://doi.org/10.3109/02656739409012373.Full Text Link to Item
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Brizel, D. M., G. L. Rosner, J. Harrelson, L. R. Prosnitz, and M. W. Dewhirst. “Pretreatment oxygenation profiles of human soft tissue sarcomas.” Int J Radiat Oncol Biol Phys 30, no. 3 (October 15, 1994): 635–42. https://doi.org/10.1016/0360-3016(92)90950-m.Full Text Link to Item
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Dewhirst, M. W., T. W. Secomb, E. T. Ong, R. Hsu, and J. F. Gross. “Determination of local oxygen consumption rates in tumors.” Cancer Res 54, no. 13 (July 1, 1994): 3333–36.Link to Item
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Dewhirst, M. W. “Future directions in hyperthermia biology.” Int J Hyperthermia 10, no. 3 (May 1994): 339–45. https://doi.org/10.3109/02656739409010277.Full Text Link to Item
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JONES, D. N., D. M. BRIZEL, H. C. CHARLES, M. W. DEWHIRST, H. S. FRIEDMAN, G. MCCOWAGE, D. M. PRESCOTT, H. D. SOSTMAN, and R. E. COLEMAN. “MONITORING OF RESPONSE TO NEOADJUVANT THERAPY OF SOFT-TISSUE AND MUSCULOSKELETAL SARCOMAS USING F-18-FDG PET.” Journal of Nuclear Medicine 35, no. 5 (May 1, 1994): P38–P38.Link to Item
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Wu, N. Z., B. A. Ross, C. Gulledge, B. Klitzman, R. Dodge, and M. W. Dewhirst. “Differences in leucocyte-endothelium interactions between normal and adenocarcinoma bearing tissues in response to radiation.” Br J Cancer 69, no. 5 (May 1994): 883–89. https://doi.org/10.1038/bjc.1994.171.Full Text Link to Item
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Clegg, S. T., T. V. Samulski, K. A. Murphy, G. L. Rosner, and M. W. Dewhirst. “Inverse techniques in hyperthermia: a sensitivity study.” Ieee Trans Biomed Eng 41, no. 4 (April 1994): 373–82. https://doi.org/10.1109/10.284965.Full Text Link to Item
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Krishna, M. C., M. W. Dewhirst, H. S. Friedman, J. A. Cook, W. DeGraff, A. Samuni, A. Russo, and J. B. Mitchell. “Hyperthermic sensitization by the radical initiator 2,2'-azobis (2-amidinopropane) dihydrochloride (AAPH). I. In vitro studies.” Int J Hyperthermia 10, no. 2 (March 1994): 271–81. https://doi.org/10.3109/02656739409009348.Full Text Link to Item
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Prescott, D. M., H. C. Charles, H. D. Sostman, R. K. Dodge, D. E. Thrall, R. L. Page, J. A. Tucker, J. M. Harrelson, K. A. Leopold, and J. R. Oleson. “Therapy monitoring in human and canine soft tissue sarcomas using magnetic resonance imaging and spectroscopy.” Int J Radiat Oncol Biol Phys 28, no. 2 (January 15, 1994): 415–23. https://doi.org/10.1016/0360-3016(94)90065-5.Full Text Link to Item
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DEWHIRST, M. “BEYOND METAFICTION - SELF-CONSCIOUSNESS IN SOVIET LITERATURE - SHEPHERD,D.” Europe Asia Studies 46, no. 1 (January 1, 1994): 160–61.Link to Item
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DEWHIRST, M. “THE LAST YEARS OF SOVIET RUSSIAN LITERATURE - PROSE-FICTION 1975-1991 - BROWN,D.” Europe Asia Studies 46, no. 3 (January 1, 1994): 554–554.Link to Item
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Kapp, Daniel S., Mark Dewhirst, and Stanley B. Field. “Dedication of the special issue of the International Journal of Hyperthermia honouring the retirement of George M. Hahn PhD.” International Journal of Hyperthermia 10, no. 3 (January 1994): 307–8. https://doi.org/10.3109/02656739409010273.Full Text
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Sostman, H. D., D. M. Prescott, M. W. Dewhirst, R. K. Dodge, D. E. Thrall, R. L. Page, J. A. Tucker, J. M. Harrelson, G. Reece, and K. A. Leopold. “MR imaging and spectroscopy for prognostic evaluation in soft-tissue sarcomas.” Radiology 190, no. 1 (January 1994): 269–75. https://doi.org/10.1148/radiology.190.1.8259418.Full Text Link to Item
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Dewhirst, M. W. “Mechanisms of hyperthermic cytotoxicity and effects at the tissue level.” American Society of Mechanical Engineers, Heat Transfer Division, (Publication) Htd 268 (December 1, 1993): 133–35.
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Leopold, K. A., J. R. Oleson, D. Clarke-Pearson, J. Soper, A. Berchuck, T. V. Samulski, R. L. Page, J. Blivin, J. K. Tomberlin, and M. W. Dewhirst. “Intraperitoneal cisplatin and regional hyperthermia for ovarian carcinoma.” Int J Radiat Oncol Biol Phys 27, no. 5 (December 1, 1993): 1245–51. https://doi.org/10.1016/0360-3016(93)90550-f.Full Text Link to Item
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Anscher, M., G. Montana, R. Dodge, E. Gaydica, M. Dewhirst, and L. Prosnitz. “The lack of impact of treatment time on the outcome of definitive radiotherapy for carcinoma of the prostate.” Int J Oncol 3, no. 4 (October 1993): 707–11. https://doi.org/10.3892/ijo.3.4.707.Full Text Link to Item
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Prescott, D. M., H. C. Charles, H. D. Sostman, R. L. Page, D. E. Thrall, D. Moore, J. R. Oleson, and M. W. Dewhirst. “Manipulation of intra- and extracellular pH in spontaneous canine tumours by use of hyperglycaemia.” Int J Hyperthermia 9, no. 5 (September 1993): 745–54. https://doi.org/10.3109/02656739309032061.Full Text Link to Item
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Wu, N. Z., B. Klitzman, G. Rosner, D. Needham, and M. W. Dewhirst. “Measurement of material extravasation in microvascular networks using fluorescence video-microscopy.” Microvasc Res 46, no. 2 (September 1993): 231–53. https://doi.org/10.1006/mvre.1993.1049.Full Text Link to Item
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Wu, N. Z., D. Da, T. L. Rudoll, D. Needham, A. R. Whorton, and M. W. Dewhirst. “Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue.” Cancer Res 53, no. 16 (August 15, 1993): 3765–70.Link to Item
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Page, R. L., M. C. McEntee, S. L. George, P. L. Williams, G. L. Heidner, C. A. Novotney, J. E. Riviere, M. W. Dewhirst, and D. E. Thrall. “Pharmacokinetic and phase I evaluation of carboplatin in dogs.” J Vet Intern Med 7, no. 4 (July 1993): 235–40. https://doi.org/10.1111/j.1939-1676.1993.tb01013.x.Full Text Link to Item
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Dewhirst, M. W., T. W. Griffin, A. R. Smith, R. G. Parker, G. E. Hanks, and L. W. Brady. “Intersociety Council on Radiation Oncology essay on the introduction of new medical treatments into practice.” J Natl Cancer Inst 85, no. 12 (June 16, 1993): 951–57. https://doi.org/10.1093/jnci/85.12.951.Full Text Link to Item
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Teicher, B. A., S. A. Holden, D. Northey, M. W. Dewhirst, and T. S. Herman. “Therapeutic effect of infused Fluosol-DA/carbogen with ephedrine, flunarizine, or nitroprusside.” Int J Radiat Oncol Biol Phys 26, no. 1 (April 30, 1993): 103–9. https://doi.org/10.1016/0360-3016(93)90179-y.Full Text Link to Item
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Leopold, K. A., M. W. Dewhirst, T. V. Samulski, R. K. Dodge, S. L. George, J. L. Blivin, L. R. Prosnitz, and J. R. Oleson. “Cumulative minutes with T90 greater than Tempindex is predictive of response of superficial malignancies to hyperthermia and radiation.” Int J Radiat Oncol Biol Phys 25, no. 5 (April 2, 1993): 841–47. https://doi.org/10.1016/0360-3016(93)90314-l.Full Text Link to Item
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Kavanagh, B. D., B. E. Coffey, D. Needham, R. M. Hochmuth, and M. W. Dewhirst. “The effect of flunarizine on erythrocyte suspension viscosity under conditions of extreme hypoxia, low pH, and lactate treatment.” Br J Cancer 67, no. 4 (April 1993): 734–41. https://doi.org/10.1038/bjc.1993.134.Full Text Link to Item
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Dewhirst, M. W. “Factors influencing hyperthermic enhancement of drug cytotoxicity.” Int J Radiat Oncol Biol Phys 25, no. 3 (February 15, 1993): 569–70. https://doi.org/10.1016/0360-3016(93)90084-9.Full Text Link to Item
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Secomb, T. W., R. Hsu, M. W. Dewhirst, B. Klitzman, and J. F. Gross. “Analysis of oxygen transport to tumor tissue by microvascular networks.” Int J Radiat Oncol Biol Phys 25, no. 3 (February 15, 1993): 481–89. https://doi.org/10.1016/0360-3016(93)90070-c.Full Text Link to Item
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NEEDHAM, D., D. DA, T. L. RUDOLL, H. P. TINGBEALL, N. WU, and M. W. DEWHIRST. “PERMEABILITY OF IMPLANTED-TUMOR VASCULATURE TO POLYMER-GRAFTED LIPOSOMES.” Biophysical Journal 64, no. 2 (February 1, 1993): A338–A338.Link to Item
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Brizel, D. M., B. Klitzman, J. M. Cook, J. Edwards, G. Rosner, and M. W. Dewhirst. “A comparison of tumor and normal tissue microvascular hematocrits and red cell fluxes in a rat window chamber model.” Int J Radiat Oncol Biol Phys 25, no. 2 (January 15, 1993): 269–76. https://doi.org/10.1016/0360-3016(93)90348-y.Full Text Link to Item
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Oleson, J. R., T. V. Samulski, K. A. Leopold, S. T. Clegg, M. W. Dewhirst, R. K. Dodge, and S. L. George. “Sensitivity of hyperthermia trial outcomes to temperature and time: implications for thermal goals of treatment.” Int J Radiat Oncol Biol Phys 25, no. 2 (January 15, 1993): 289–97. https://doi.org/10.1016/0360-3016(93)90351-u.Full Text Link to Item
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Acker, J. C., D. P. Spencer, W. Yang, M. A. Avery, R. K. Dodge, L. B. Marks, and M. W. Dewhirst. “Serial in vivo observations of cerebral vasculature after a single fraction of radiation using a rat brain window.” International Journal of Radiation Oncology*Biology*Physics 27 (1993): 321–321. https://doi.org/10.1016/0360-3016(93)90948-u.Full Text
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Castellino, S., G. B. Elion, O. W. Griffith, M. Dewhirst, J. Kurtzberg, R. C. Cattley, P. Scott, D. D. Bigner, and H. S. Friedman. “Development of a model of melphalan-induced gastrointestinal toxicity in mice.” Cancer Chemother Pharmacol 31, no. 5 (1993): 376–80. https://doi.org/10.1007/BF00686151.Full Text Link to Item
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Dewhirst, M. W., D. Madwed, R. E. Meyer, E. T. Ong, B. Klitzman, G. L. Rosner, and R. Dodge. “Reduction in tumor blood flow in skin flap tumor after hydralazine is not due to a vascular steal phenomenon.” Radiation Oncology Investigations 1, no. 5 (January 1, 1993): 270–78. https://doi.org/10.1002/roi.2970010504.Full Text
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Secomb, T. W., R. Hsu, and M. W. Dewhirst. “Models for oxygen exchange between microvascular networks and surrounding tissue.” American Society of Mechanical Engineers, Heat Transfer Division, (Publication) Htd 231 (December 1, 1992): 121–27.
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Page, R. L., D. E. Thrall, S. L. George, G. S. Price, G. L. Heidner, M. C. McEntee, C. A. Novotney, M. L. Hauck, and M. W. Dewhirst. “Quantitative estimation of the thermal dose-modifying factor for cis-diamminedichloroplatinum (CDDP) in tumour-bearing dogs.” Int J Hyperthermia 8, no. 6 (November 1992): 761–69. https://doi.org/10.3109/02656739209005024.Full Text Link to Item
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Dewhirst, M. W., E. T. Ong, D. Madwed, B. Klitzman, T. Secomb, D. Brizel, J. Bonaventura, G. Rosner, B. Kavanagh, and J. Edwards. “Effects of the calcium channel blocker flunarizine on the hemodynamics and oxygenation of tumor microvasculature.” Radiat Res 132, no. 1 (October 1992): 61–68.Link to Item
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Wu, N. Z., B. Klitzman, R. Dodge, and M. W. Dewhirst. “Diminished leukocyte-endothelium interaction in tumor microvessels.” Cancer Res 52, no. 15 (August 1, 1992): 4265–68.Link to Item
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Novotney, C. A., R. L. Page, D. W. Macy, M. W. Dewhirst, G. K. Ogilvie, S. J. Withrow, M. C. McEntee, G. L. Heidner, S. A. Allen, and D. E. Thrall. “Phase I evaluation of doxorubicin and whole-body hyperthermia in dogs with lymphoma.” J Vet Intern Med 6, no. 4 (July 1992): 245–49. https://doi.org/10.1111/j.1939-1676.1992.tb00346.x.Full Text Link to Item
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Dewhirst, M. W., R. Z. Vinuya, E. T. Ong, B. Klitzman, G. Rosner, T. W. Secomb, and J. F. Gross. “Effects of bradykinin on the hemodynamics of tumor and granulating normal tissue microvasculature.” Radiat Res 130, no. 3 (June 1992): 345–54.Link to Item
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Dewhirst, M. W., E. T. Ong, B. Klitzman, T. W. Secomb, R. Z. Vinuya, R. Dodge, D. Brizel, and J. F. Gross. “Perivascular oxygen tensions in a transplantable mammary tumor growing in a dorsal flap window chamber.” Radiat Res 130, no. 2 (May 1992): 171–82.Link to Item
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Gillette, S. M., M. W. Dewhirst, E. L. Gillette, D. E. Thrall, R. L. Page, B. E. Powers, S. J. Withrow, G. Rosner, C. Wong, and D. A. Sim. “Response of canine soft tissue sarcomas to radiation or radiation plus hyperthermia: a randomized phase II study.” Int J Hyperthermia 8, no. 3 (May 1992): 309–20. https://doi.org/10.3109/02656739209021786.Full Text Link to Item
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Laskowitz, D. T., G. B. Elion, M. W. Dewhirst, O. W. Griffith, R. A. Casero, P. A. Scott, N. Bullock, D. D. Bigner, and H. S. Friedman. “Effects of glutathione or polyamine depletion on in vivo thermosensitization.” Int J Hyperthermia 8, no. 2 (March 1992): 199–208. https://doi.org/10.3109/02656739209021775.Full Text Link to Item
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Page, R. L., D. W. Macy, G. K. Ogilvie, G. L. Rosner, M. W. Dewhirst, D. E. Thrall, S. J. Withrow, M. C. McEntee, J. M. Cline, and G. L. Heidner. “Phase III evaluation of doxorubicin and whole-body hyperthermia in dogs with lymphoma.” Int J Hyperthermia 8, no. 2 (March 1992): 187–97. https://doi.org/10.3109/02656739209021774.Full Text Link to Item
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Laskowitz, D. T., G. B. Elion, M. W. Dewhirst, O. W. Griffith, P. M. Savina, M. R. Blum, D. M. Prescott, D. D. Bigner, and H. S. Friedman. “Hyperthermia-induced enhancement of melphalan activity against a melphalan-resistant human rhabdomyosarcoma xenograft.” Radiat Res 129, no. 2 (February 1992): 218–23.Link to Item
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Laskowitz, D. T., G. B. Elion, M. W. Dewhirst, O. W. Griffith, R. C. Cattley, D. D. Bigner, and H. S. Friedman. “Enhancement of melphalan-induced gastrointestinal toxicity in mice treated with regional hyperthermia and BSO-mediated glutathione depletion.” Int J Hyperthermia 8, no. 1 (January 1992): 111–20. https://doi.org/10.3109/02656739209052883.Full Text Link to Item
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Leopold, K. A., M. Dewhirst, T. Samulski, J. Harrelson, J. A. Tucker, S. L. George, R. K. Dodge, W. Grant, S. Clegg, and L. R. Prosnitz. “Relationships among tumor temperature, treatment time, and histopathological outcome using preoperative hyperthermia with radiation in soft tissue sarcomas.” Int J Radiat Oncol Biol Phys 22, no. 5 (1992): 989–98. https://doi.org/10.1016/0360-3016(92)90798-m.Full Text Link to Item
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Prescott, D. M., T. V. Samulski, M. W. Dewhirst, R. L. Page, D. E. Thrall, R. K. Dodge, and J. R. Oleson. “Use of nitroprusside to increase tissue temperature during local hyperthermia in normal and tumor-bearing dogs.” Int J Radiat Oncol Biol Phys 23, no. 2 (1992): 377–85. https://doi.org/10.1016/0360-3016(92)90756-8.Full Text Link to Item
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Rine, G. P., M. W. Dewhirst, E. D. Cobb, S. T. Clegg, E. N. Coleman, T. V. Samulski, and C. A. Wallen. “Feasibility of estimating the temperature distribution in a tumor heated by a waveguide applicator.” Int J Radiat Oncol Biol Phys 23, no. 5 (1992): 1009–19. https://doi.org/10.1016/0360-3016(92)90907-y.Full Text Link to Item
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Thrall, D. E., D. M. Prescott, T. V. Samulski, M. W. Dewhirst, J. M. Cline, J. Lee, R. L. Page, and J. R. Oleson. “Serious toxicity associated with annular microwave array induction of whole-body hyperthermia in normal dogs.” Int J Hyperthermia 8, no. 1 (January 1992): 23–32. https://doi.org/10.3109/02656739209052876.Full Text Link to Item
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Needham, D., K. Hristova, T. J. Mcintosh, M. Dewhirst, N. Wu, and D. D. Lasic. “Polymer-grafted liposomes: Physical basis for the "stealth" property.” Journal of Liposome Research 2, no. 3 (January 1, 1992): 411–30. https://doi.org/10.3109/08982109209010218.Full Text
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Marks, L. B., and M. Dewhirst. “Accelerated repopulation: friend or foe? Exploiting changes in tumor growth characteristics to improve the "efficiency" of radiotherapy.” Int J Radiat Oncol Biol Phys 21, no. 5 (October 1991): 1377–83. https://doi.org/10.1016/0360-3016(91)90301-j.Full Text Link to Item
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Lilley, E. R., G. B. Elion, M. W. Dewhirst, S. C. Schold, M. R. Blum, P. M. Savina, D. T. Laskowitz, D. D. Bigner, and H. S. Friedman. “Therapeutic analysis of melphalan-resistant human rhabdomyosarcoma xenograft TE-671 MR.” Cancer Res 51, no. 15 (August 1, 1991): 3906–9.Link to Item
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Page, R. L., D. E. Thrall, M. W. Dewhirst, D. W. Macy, S. L. George, M. C. McEntee, G. L. Heidner, C. A. Novotney, S. A. Allen, and S. J. Withrow. “Phase I study of melphalan alone and melphalan plus whole body hyperthermia in dogs with malignant melanoma.” Int J Hyperthermia 7, no. 4 (July 1991): 559–66. https://doi.org/10.3109/02656739109034968.Full Text Link to Item
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Emami, B., P. Stauffer, M. W. Dewhirst, S. Prionas, T. Ryan, P. Corry, T. Herman, D. S. Kapp, R. J. Myerson, and T. Samulski. “RTOG quality assurance guidelines for interstitial hyperthermia.” Int J Radiat Oncol Biol Phys 20, no. 5 (May 1991): 1117–24. https://doi.org/10.1016/0360-3016(91)90213-n.Full Text Link to Item
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Sapozink, M. D., P. M. Corry, D. S. Kapp, R. J. Myerson, M. W. Dewhirst, B. Emami, T. Herman, S. Prionas, T. Ryan, and T. Samulski. “RTOG quality assurance guidelines for clinical trials using hyperthermia for deep-seated malignancy.” Int J Radiat Oncol Biol Phys 20, no. 5 (May 1991): 1109–15. https://doi.org/10.1016/0360-3016(91)90212-m.Full Text Link to Item
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Waterman, F. M., M. W. Dewhirst, P. Fessenden, T. V. Samulski, P. Stauffer, B. Emami, P. Corry, S. D. Prionas, M. Sapozink, and T. Herman. “RTOG quality assurance guidelines for clinical trials using hyperthermia administered by ultrasound.” Int J Radiat Oncol Biol Phys 20, no. 5 (May 1991): 1099–1107. https://doi.org/10.1016/0360-3016(91)90211-l.Full Text Link to Item
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Dewhirst, M. W., D. M. Prescott, S. Clegg, T. V. Samulski, R. L. Page, D. E. Thrall, K. Leopold, G. Rosner, J. C. Acker, and J. R. Oleson. “The use of hydralazine to manipulate tumour temperatures during hyperthermia.” Int J Hyperthermia 6, no. 6 (November 1990): 971–83. https://doi.org/10.3109/02656739009140980.Full Text Link to Item
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Samulski, T. V., W. J. Grant, J. R. Oleson, K. A. Leopold, M. W. Dewhirst, P. Vallario, and J. Blivin. “Clinical experience with a multi-element ultrasonic hyperthermia system: analysis of treatment temperatures.” Int J Hyperthermia 6, no. 5 (September 1990): 909–22. https://doi.org/10.3109/02656739009140972.Full Text Link to Item
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Sostman, H. D., H. C. Charles, S. Rockwell, K. Leopold, C. Beam, D. Madwed, M. Dewhirst, G. Cofer, D. Moore, and R. Burn. “Soft-tissue sarcomas: detection of metabolic heterogeneity with P-31 MR spectroscopy.” Radiology 176, no. 3 (September 1990): 837–43. https://doi.org/10.1148/radiology.176.3.2389045.Full Text Link to Item
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Dewhirst, M. W., T. L. Phillips, T. V. Samulski, P. Stauffer, P. Shrivastava, B. Paliwal, T. Pajak, M. Gillim, M. Sapozink, and R. Myerson. “RTOG quality assurance guidelines for clinical trials using hyperthermia.” Int J Radiat Oncol Biol Phys 18, no. 5 (May 1990): 1249–59. https://doi.org/10.1016/0360-3016(90)90466-w.Full Text Link to Item
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Riviere, J. E., R. L. Page, R. A. Rogers, S. K. Chang, M. W. Dewhirst, and D. E. Thrall. “Nonuniform alteration of cis-diamminedichloroplatinum(II) tissue distribution in dogs with whole body hyperthermia.” Cancer Res 50, no. 7 (April 1, 1990): 2075–80.Link to Item
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Cope, D. A., M. W. Dewhirst, H. S. Friedman, D. D. Bigner, and M. R. Zalutsky. “Enhanced delivery of a monoclonal antibody F(ab')2 fragment to subcutaneous human glioma xenografts using local hyperthermia.” Cancer Res 50, no. 6 (March 15, 1990): 1803–9.Link to Item
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Acker, J. C., M. W. Dewhirst, G. M. Honoré, T. V. Samulski, J. A. Tucker, and J. R. Oleson. “Blood perfusion measurements in human tumours: evaluation of laser Doppler methods.” Int J Hyperthermia 6, no. 2 (March 1990): 287–304. https://doi.org/10.3109/02656739009141139.Full Text Link to Item
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Dewhirst, M. W., H. D. Sostman, K. A. Leopold, H. C. Charles, D. Moore, R. A. Burn, J. A. Tucker, J. M. Harrelson, and J. R. Oleson. “Soft-tissue sarcomas: MR imaging and MR spectroscopy for prognosis and therapy monitoring. Work in progress.” Radiology 174, no. 3 Pt 1 (March 1990): 847–53. https://doi.org/10.1148/radiology.174.3.2154837.Full Text Link to Item
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Dewhirst, M. W., R. Oliver, C. Y. Tso, C. Gustafson, T. Secomb, and J. F. Gross. “Heterogeneity in tumor microvascular response to radiation.” Int J Radiat Oncol Biol Phys 18, no. 3 (March 1990): 559–68. https://doi.org/10.1016/0360-3016(90)90061-n.Full Text Link to Item
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Thrall, D. E., M. W. Dewhirst, R. L. Page, T. V. Samulski, D. A. McLeod, and J. R. Oleson. “A comparison of temperatures in canine solid tumours during local and whole-body hyperthermia administered alone and simultaneously.” Int J Hyperthermia 6, no. 2 (March 1990): 305–17. https://doi.org/10.3109/02656739009141140.Full Text Link to Item
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Dewhirst, Martin. “The Foreign Office and the famine: British documents on Ukraine and the Great Famine of 1932–1933.” International Affairs 66, no. 1 (January 1990): 171–72. https://doi.org/10.2307/2622228.Full Text
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Edelstein-Keshet, L., M. W. Dewhirst, J. R. Oleson, and T. V. Samulski. “Characterization of tumour temperature distributions in hyperthermia based on assumed mathematical forms.” Int J Hyperthermia 5, no. 6 (November 1989): 757–77. https://doi.org/10.3109/02656738909140500.Full Text Link to Item
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Dewhirst, M. W., C. Y. Tso, R. Oliver, C. S. Gustafson, T. W. Secomb, and J. F. Gross. “Morphologic and hemodynamic comparison of tumor and healing normal tissue microvasculature.” Int J Radiat Oncol Biol Phys 17, no. 1 (July 1989): 91–99. https://doi.org/10.1016/0360-3016(89)90375-1.Full Text Link to Item
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Dewhirst, M. W. “Animal modeling and thermal dose.” Radiol Clin North Am 27, no. 3 (May 1989): 509–18.Link to Item
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Oleson, J. R., M. W. Dewhirst, J. M. Harrelson, K. A. Leopold, T. V. Samulski, and C. Y. Tso. “Tumor temperature distributions predict hyperthermia effect.” Int J Radiat Oncol Biol Phys 16, no. 3 (March 1989): 559–70. https://doi.org/10.1016/0360-3016(89)90472-0.Full Text Link to Item
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Shrivastava, P., K. Luk, J. Oleson, M. Dewhirst, T. Pajak, B. Paliwal, C. Perez, S. Sapareto, T. Saylor, and R. Steeves. “Hyperthermia quality assurance guidelines.” Int J Radiat Oncol Biol Phys 16, no. 3 (March 1989): 571–87. https://doi.org/10.1016/0360-3016(89)90473-2.Full Text Link to Item
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Thrall, D. E., R. L. Page, M. W. Dewhirst, D. W. Macy, D. A. McLeod, R. J. Scott, S. Allen, and E. L. Gillette. “Whole body hyperthermia in dogs using a radiant heating device: effect of surface cooling on temperature uniformity.” Int J Hyperthermia 5, no. 2 (March 1989): 137–43. https://doi.org/10.3109/02656738909140443.Full Text Link to Item
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Engler, M. J., M. W. Dewhirst, and J. R. Oleson. “Stability of temperatures during hyperthermia treatments.” Int J Hyperthermia 5, no. 1 (January 1989): 59–67. https://doi.org/10.3109/02656738909140433.Full Text Link to Item
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Leopold, K. A., J. Harrelson, L. Prosnitz, T. V. Samulski, M. W. Dewhirst, and J. R. Oleson. “Preoperative hyperthermia and radiation for soft tissue sarcomas: advantage of two vs one hyperthermia treatments per week.” Int J Radiat Oncol Biol Phys 16, no. 1 (January 1989): 107–15. https://doi.org/10.1016/0360-3016(89)90017-5.Full Text Link to Item
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McChesney, S. L., S. J. Withrow, E. L. Gillette, B. E. Powers, and M. W. Dewhirst. “Radiotherapy of soft tissue sarcomas in dogs.” J Am Vet Med Assoc 194, no. 1 (January 1, 1989): 60–63.Link to Item
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Thrall, D. E., D. A. McLeod, G. C. Bentel, and M. W. Dewhirst. “A REVIEW OF TREATMENT PLANNING AND DOSE CALCULATION IN VETERINARY RADIATION ONCOLOGY.” Veterinary Radiology 30, no. 5 (January 1, 1989): 194–221. https://doi.org/10.1111/j.1740-8261.1989.tb00776.x.Full Text
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Oleson, J. R., S. K. Calderwood, C. T. Coughlin, M. W. Dewhirst, L. E. Gerweck, F. A. Gibbs, and D. S. Kapp. “Biological and clinical aspects of hyperthermia in cancer therapy.” Am J Clin Oncol 11, no. 3 (June 1988): 368–80. https://doi.org/10.1097/00000421-198806000-00013.Full Text Link to Item
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Page, R. L., D. W. Macy, D. E. Thrall, M. W. Dewhirst, S. L. Allen, G. L. Heidner, D. A. Sim, M. L. McGee, and E. L. Gillette. “Unexpected toxicity associated with use of body surface area for dosing melphalan in the dog.” Cancer Res 48, no. 2 (January 15, 1988): 288–90.Link to Item
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Dewhirst, M. W., C. Gustafson, J. F. Gross, and C. Y. Tso. “Temporal effects of 5.0 Gy radiation in healing subcutaneous microvasculature of a dorsal flap window chamber.” Radiat Res 112, no. 3 (December 1987): 581–91.Link to Item
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Gillette, E. L., S. L. McChesney, M. W. Dewhirst, and R. J. Scott. “Response of canine oral carcinomas to heat and radiation.” Int J Radiat Oncol Biol Phys 13, no. 12 (December 1987): 1861–67. https://doi.org/10.1016/0360-3016(87)90353-1.Full Text Link to Item
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Rine, G., M. W. Dewhirst, T. V. Samulski, and A. Wallen. “MODELING OF SAR VALUES IN TISSUE DUE TO SLAB LOADED WAVEGUIDE APPLICATORS.” Ieee/Engineering in Medicine and Biology Society Annual Conference, December 1, 1987, 1000–1001.
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GILLETTE, E. L., S. L. ALLEN, M. W. DEWHIRST, D. W. MACY, R. L. PAGE, D. A. SIM, D. E. THRALL, and N. C. POSTORINO. “WHOLE-BODY HYPERTHERMIA AND CHEMOTHERAPY FOR CANINE LYMPHOMAS.” International Journal of Hyperthermia 3, no. 6 (November 1, 1987): 564–65.Link to Item
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GILLETTE, E. L., S. L. MCCHESNEY, and M. W. DEWHIRST. “THERMORADIOTHERAPY OF CANINE TUMORS.” International Journal of Hyperthermia 3, no. 6 (November 1, 1987): 565–565.Link to Item
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Page, R. L., R. E. Meyer, D. E. Thrall, and M. W. Dewhirst. “Cardiovascular and metabolic response of tumour-bearing dogs to whole body hyperthermia.” Int J Hyperthermia 3, no. 6 (November 1987): 513–25. https://doi.org/10.3109/02656738709140424.Full Text Link to Item
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Zakris, E. L., M. W. Dewhirst, J. E. Riviere, P. J. Hoopes, R. L. Page, and J. R. Oleson. “Pharmacokinetics and toxicity of intraperitoneal cisplatin combined with regional hyperthermia.” J Clin Oncol 5, no. 10 (October 1987): 1613–20. https://doi.org/10.1200/JCO.1987.5.10.1613.Full Text Link to Item
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Engler, M. J., M. W. Dewhirst, J. M. Winget, and J. R. Oleson. “Automated temperature scanning for hyperthermia treatment monitoring.” Int J Radiat Oncol Biol Phys 13, no. 9 (September 1987): 1377–82. https://doi.org/10.1016/0360-3016(87)90233-1.Full Text Link to Item
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Dewhirst, M. W., J. M. Winget, L. Edelstein-Keshet, J. Sylvester, M. Engler, D. E. Thrall, R. L. Page, and J. R. Oleson. “Clinical application of thermal isoeffect dose.” Int J Hyperthermia 3, no. 4 (July 1987): 307–18. https://doi.org/10.3109/02656738709140401.Full Text Link to Item
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Page, R. L., D. E. Thrall, M. W. Dewhirst, and R. E. Meyer. “Whole-body hyperthermia. Rationale and potential use for cancer treatment.” J Vet Intern Med 1, no. 3 (July 1987): 110–20. https://doi.org/10.1111/j.1939-1676.1987.tb01998.x.Full Text Link to Item
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Klein, M. K., M. W. Dewhirst, and D. J. Fuller. “Whole body hyperthermia and heat-sensitizing drugs: a pilot study in canine lymphoproliferative disease.” Int J Hyperthermia 3, no. 3 (May 1987): 187–98. https://doi.org/10.3109/02656738709140386.Full Text Link to Item
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DEWHIRST, M. “SOVIET DISSENT - CONTEMPORARY-MOVEMENTS FOR NATIONAL, RELIGIOUS, AND HUMAN-RIGHTS - ALEXEYEVA,L.” Soviet Studies 39, no. 1 (January 1, 1987): 156–58.Link to Item
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Dewhirst, M. W., J. F. Gross, and D. A. Sim. “EFFECTS OF HEATING RATE ON NORMAL AND TUMOR MICROCIRCULATORY FUNCTION.” American Society of Mechanical Engineers, Heat Transfer Division, (Publication) Htd 61 (December 1, 1986): 75–80.
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THRALL, D. E., R. L. PAGE, M. W. DEWHIRST, R. E. MEYER, P. J. HOOPES, and J. N. KORNEGAY. “TEMPERATURE-MEASUREMENTS IN NORMAL AND TUMOR-TISSUE OF DOGS UNDERGOING WHOLE-BODY HYPERTHERMIA.” Cancer Research 46, no. 12 (December 1, 1986): 6229–35.Link to Item
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Thrall, D. E., R. L. Page, M. W. Dewhirst, R. E. Meyer, P. J. Hoopes, and J. N. Kornegay. “Temperature measurements in normal and tumor tissue of dogs undergoing whole body hyperthermia.” Cancer Res 46, no. 12 Pt 1 (December 1986): 6229–35.Link to Item
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Winget, J. M., M. W. Dewhirst, M. J. Engler, and J. R. Oleson. “USE OF LIMITED TEMPERATURE OBSERVATIONS TO PREDICT COMPLETE TEMPERATURE FIELDS.” Ieee/Engineering in Medicine and Biology Society Annual Conference, December 1, 1986, 1507–11.
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McChesney, S. L., E. L. Gillette, M. W. Dewhirst, and S. J. Withrow. “Influence of WR 2721 on radiation response of canine soft tissue sarcomas.” Int J Radiat Oncol Biol Phys 12, no. 11 (November 1986): 1957–63. https://doi.org/10.1016/0360-3016(86)90132-x.Full Text Link to Item
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Meyer, R. E., R. L. Page, D. E. Thrall, M. W. Dewhirst, and D. L. Vose. “Determination of continuous atracurium infusion rate in dogs undergoing whole-body hyperthermia.” Cancer Res 46, no. 11 (November 1986): 5599–5601.Link to Item
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Riviere, J. E., R. L. Page, M. W. Dewhirst, K. Tyczkowska, and D. E. Thrall. “Effect of hyperthermia on cisplatin pharmacokinetics in normal dogs.” Int J Hyperthermia 2, no. 4 (October 1986): 351–58. https://doi.org/10.3109/02656738609004965.Full Text Link to Item
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Dewhirst, M. W., and D. A. Sim. “Estimation of therapeutic gain in clinical trials involving hyperthermia and radiotherapy.” Int J Hyperthermia 2, no. 2 (April 1986): 165–78. https://doi.org/10.3109/02656738609012392.Full Text Link to Item
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Dewhirst, Martin. “The Soviet government and the Jews, 1948–1967: a documented study.” International Affairs 62, no. 4 (1986): 687–88. https://doi.org/10.2307/2618605.Full Text
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Thrall, D. E., R. L. Page, R. E. Meyer, P. J. Hoopes, J. N. Kornegay, and M. W. Dewhirst. “Temperature Measurements in Normal and Tumor Tissue of Dogs Undergoing Whole Body Hyperthermia.” Cancer Research 46 (January 1, 1986): 6229–35.
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Dewhirst, M. W. “BIOLOGICAL RATIONALE AND CLINICAL OVERVIEW OF HYPERTHERMIA.” Advances in Bioengineering, December 1, 1985, 63–64.
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Dewhirst, M. W. “CONSIDERATIONS IN THE CORRELATION BETWEEN THERMAL DOSE AND TUMOR AND NORMAL TISSUE RESPONSE.” Ieee/Engineering in Medicine and Biology Society Annual Conference, December 1, 1985, 55–59.
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Oleson, J. R., M. W. Dewhirst, D. Duncan, M. Engler, and D. Thrall. “TEMPERATURE GRADIENTS: PROGNOSTIC AND DOSIMETRIC IMPLICATIONS.” Ieee/Engineering in Medicine and Biology Society Annual Conference, December 1, 1985, 355–60.
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Dewhirst, M. W., D. A. Sim, K. Forsyth, K. J. Grochowski, S. Wilson, and E. Bicknell. “Local control and distant metastases in primary canine malignant melanomas treated with hyperthermia and/or radiotherapy.” Int J Hyperthermia 1, no. 3 (July 1985): 219–34. https://doi.org/10.3109/02656738509029287.Full Text Link to Item
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Thrall, D. E., and M. W. Dewhirst. “Use of radiation and/or hyperthermia for treatment of mast cell tumors and lymphosarcoma in dogs.” Vet Clin North Am Small Anim Pract 15, no. 4 (July 1985): 835–43. https://doi.org/10.1016/s0195-5616(85)50040-6.Full Text Link to Item
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DEWHIRST, M. W. “CONSIDERATIONS IN THE CORRELATION BETWEEN THERMAL DOSE AND TUMOR OR NORMAL TISSUE-RESPONSE.” Ieee Transactions on Biomedical Engineering 32, no. 10 (January 1, 1985): 867–867.Link to Item
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ENGLER, M. J., M. C. KOHN, W. T. JOINES, M. W. DEWHIRST, and J. R. OLESON. “COMPUTER-SIMULATION OF CANCER THERMOTHERAPY.” Medical Physics 12, no. 5 (January 1, 1985): 671–671.Link to Item
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OLESON, J. R., M. W. DEWHIRST, D. DUNCAN, M. ENGLER, and D. THRALL. “TEMPERATURE-GRADIENTS - PROGNOSTIC AND DOSIMETRIC IMPLICATIONS.” Ieee Transactions on Biomedical Engineering 32, no. 10 (January 1, 1985): 877–877.Link to Item
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Dewhirst, M. W., and D. A. Sim. “The utility of thermal dose as a predictor of tumor and normal tissue responses to combined radiation and hyperthermia.” Cancer Res 44, no. 10 Suppl (October 1984): 4772s-4780s.Link to Item
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Oleson, J. R., A. Assaad, M. W. Dewhirst, D. W. DeYoung, K. J. Grochowski, and D. A. Sim. “Regional hyperthermia by magnetic induction in a beagle dog model: analysis of thermal dosimetry.” Radiat Res 98, no. 3 (June 1984): 445–55.Link to Item
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DEWHIRST, M. W., and D. A. SIM. “THE UTILITY OF THERMAL DOSE AS A PREDICTOR OF TUMOR AND NORMAL TISSUE RESPONSES TO COMBINED RADIATION AND HYPERTHERMIA.” Cancer Research 44, no. 10 (January 1, 1984): 4772–80.Link to Item
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DEWHIRST, M. W., and D. A. SIM. “THE UTILITY OF THERMAL DOSE AS A PREDICTOR OF TUMOR AND NORMAL TISSUE RESPONSES TO COMBINED RADIATION AND HYPERTHERMIA.” Cancer Research 44, no. 10 (1984): 4772–80.Link to Item
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DEWHIRST, M. “PERMITTED DISSENT IN THE USSR - NOVY-MIR AND THE SOVIET REGIME - SPECHLER,DR.” Soviet Studies 36, no. 3 (January 1, 1984): 459–60.Link to Item
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Dewhirst, M. W., D. A. Sim, S. Sapareto, and W. G. Connor. “Importance of minimum tumor temperature in determining early and long-term responses of spontaneous canine and feline tumors to heat and radiation.” Cancer Res 44, no. 1 (January 1984): 43–50.Link to Item
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Dewhirst, M. W., and D. A. Sim. “Analysis of prognostic variables which influence early and long-term response of pet animal tumors to radiation alone and radiation plus heat.” Front Radiat Ther Oncol 18 (1984): 47–55. https://doi.org/10.1159/000429199.Full Text Link to Item
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Dewhirst, M. W., and D. A. Sim. “The utility of thermal dose as a predictor of tumor and normal tissue responses to combined radiation and hyperthermia.” Cancer Research 44, no. 10 SUPPL. (January 1, 1984).
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Dewhirst, M., J. F. Gross, D. Sim, P. Arnold, and D. Boyer. “The effect of rate of heating or cooling prior to heating on tumor and normal tissue microcirculatory blood flow.” Biorheology 21, no. 4 (1984): 539–58. https://doi.org/10.3233/bir-1984-21413.Full Text Link to Item
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Stauffer, P. R., T. C. Cetas, A. M. Fletcher, D. W. DeYoung, M. W. Dewhirst, J. R. Oleson, and R. B. Roemer. “OBSERVATIONS ON THE USE OF FERROMAGNETIC IMPLANTS FOR INDUCTING HYPERTHERMIA.” Ieee Transactions on Biomedical Engineering BME-31, no. 1 (1984): 76–90.
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Stauffer, P. R., T. C. Cetas, A. M. Fletcher, D. W. DeYoung, M. W. Dewhirst, J. R. Oleson, and R. B. Roemer. “Observations on the use of ferromagnetic implants for inducing hyperthermia.” Ieee Trans Biomed Eng 31, no. 1 (January 1984): 76–90. https://doi.org/10.1109/TBME.1984.325373.Full Text Link to Item
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Dewhirst, M. W., D. A. Sim, J. L. Parsells, S. Wilson, and D. DeYoung. “Correlation between Initial and Long-Term Responses of Spontaneous Pet Animal Tumors to Heat and Radiation or Radiation Alone.” Cancer Research 43, no. 20 (December 1, 1983): 5735–41.
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Dewhirst, M. W., D. A. Sim, S. Wilson, D. DeYoung, and J. L. Parsells. “Correlation between initial and long-term responses of spontaneous pet animal tumors to heat and radiation or radiation alone.” Cancer Res 43, no. 12 Pt 1 (December 1983): 5735–41.Link to Item
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Oleson, J. R., and M. W. Dewhirst. “Hyperthermia: an overview of current progress and problems.” Curr Probl Cancer 8, no. 6 (December 1983): 1–62. https://doi.org/10.1016/s0147-0272(83)80004-x.Full Text Link to Item
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DEWHIRST, M. W., D. A. SIM, S. WILSON, D. DEYOUNG, and J. L. PARSELLS. “CORRELATION BETWEEN INITIAL AND LONG-TERM RESPONSES OF SPONTANEOUS PET ANIMAL TUMORS TO HEAT AND RADIATION OR RADIATION ALONE.” Cancer Research 43, no. 12 (January 1, 1983): 5735–41.Link to Item
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DEWHIRST, M. W., D. A. SIM, and S. A. SAPARETO. “THE IMPORTANCE OF MINIMUM TUMOR TEMPERATURES IN DETERMINING EARLY AND LONG-TERM RESPONSES OF SPONTANEOUS PET ANIMAL TUMORS TO HEAT AND RADION.” Radiation Research 94, no. 3 (January 1, 1983): 538–39.Link to Item
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DEWHIRST, M. W., J. GROSS, and M. KUNDRAT. “EFFECT OF RATE OF HEATING ON TUMOR AND NORMAL TISSUE MICRO-CIRCULATION.” Radiation Research 94, no. 3 (January 1, 1983): 537–38.Link to Item
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DEWHIRST, M. W., and J. F. GROSS. “THE EFFECT OF THE RATE OF HEATING ON MICROVASCULAR RESPONSE IN NORMAL AND NEOPLASTIC TISSUE.” Biorheology 20, no. 4 (January 1, 1983): 397–397.Link to Item
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DEWHIRST, M. “NOVY MIR - A CASE-STUDY IN THE POLITICS OF LITERATURE 1952-1958 - FRANKEL,ER.” Soviet Studies 35, no. 2 (January 1, 1983): 261–62.Link to Item
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Dewhirst, M. W., W. G. Connor, and D. A. Sim. “Preliminary results of a phase III trial of spontaneous animal tumors to heat and/or radiation: early normal tissue response and tumor volume influence on initial response.” Int J Radiat Oncol Biol Phys 8, no. 11 (November 1982): 1951–61. https://doi.org/10.1016/0360-3016(82)90455-2.Full Text Link to Item
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CETAS, T. C., M. W. DEWHIRST, D. W. DEYOUNG, A. M. FLETCHER, J. R. OLESON, and P. R. STAUFFER. “THE CLINICAL USE OF INDUCTIVELY HEATED FERROMAGNETIC IMPLANTS FOR TREATING DEEP-SEATED LESIONS - ANIMAL TRIALS.” Radiation Research 91, no. 2 (January 1, 1982): 420–420.Link to Item
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DEWHIRST, M. W., D. A. SIM, and J. PARSELLS. “HEAT DOSE IN A RANDOMIZED TRIAL OF HEAT PLUS RADIATION (DELTA + XRT) AND RADIATION ALONE (XRT) IN SPONTANEOUS PET ANIMAL TUMORS.” Radiation Research 91, no. 2 (January 1, 1982): 421–421.Link to Item
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DEWHIRST, M. W., D. A. SIM, and J. PARSELLS. “INITIAL RESPONSE AS A PREDICTOR OF ULTIMATE BENEFIT OF HEAT (DELTA) PLUS RADIATION (XRT) OVER XRT ALONE IN A RANDOMIZED TRIAL UTILIZING PET ANIMAL TUMORS.” Radiation Research 91, no. 2 (January 1, 1982): 420–420.Link to Item
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DEWHIRST, M. W., and J. F. GROSS. “DEVELOPMENT OF A UNIFORM HEATING TECHNIQUE FOR THE ARIZONA CHAMBER WITH MEASUREMENT OF SINGLE VESSEL FLOW ALTERATIONS DURING HYPERTHERMIA.” Proceedings of the American Association for Cancer Research 23, no. MAR (January 1, 1982): 27–27.Link to Item
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Gross, J. F., R. Roemer, M. Dewhirst, and T. Meyer. “A uniform thermal field in a hyperthermia chamber for microvascular studies.” International Journal of Heat and Mass Transfer 25, no. 9 (January 1, 1982): 1313–20. https://doi.org/10.1016/0017-9310(82)90125-9.Full Text
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Nasoni, R. L., T. Bowen, M. W. Dewhirst, H. B. Roth, and R. Premovich. “SPEED OF SOUND AS A THERMAL IMAGE CT SCAN PARAMETER.” Acoustical Imaging: Proceedings of the International Symposium 11 (January 1, 1982): 563–82. https://doi.org/10.1007/978-1-4684-1137-9_37.Full Text
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DEWHIRST, M. W., W. J. CONNOR, H. ROTH, T. MOON, and S. WILSON. “A COMPARISON OF HEAT, RADIATION AND HEAT PLUS RADIATION IN A PHASE-III RANDOMIZED TRIAL USING SPONTANEOUS MALIGNANCIES IN PET ANIMALS.” Radiation Research 87, no. 2 (January 1, 1981): 415–415.Link to Item
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Dewhirst, M. W., E. J. Ozimek, J. Gross, and T. C. Cetas. “Will hyperthermia conquer the elusive hypoxic cell? Implications of heat effects on tumor and normal-tissue microcirculation.” Radiology 137, no. 3 (December 1980): 811–17. https://doi.org/10.1148/radiology.137.3.7003650.Full Text Link to Item
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DEWHIRST, M. “SOVIET BOOK PUBLISHING POLICY - WALKER,G.” Soviet Studies 31, no. 2 (January 1, 1979): 304–6.Link to Item
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DEWHIRST, M. “DECADE OF EUPHORIA - WESTERN LITERATURE IN POST-STALIN RUSSIA, 1954-64 - FRIEDBERG,M.” Soviet Studies 31, no. 2 (January 1, 1979): 303–4.Link to Item
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Phillips, R. K., M. W. Dewhirst, E. L. Gillette, and D. J. Clow. “Electrophoretic evaluation of sera from dogs with cancer.” Am J Vet Res 39, no. 9 (September 1978): 1482–86.Link to Item
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DEWHIRST, M. “DETENTE AFTER BREZHNEV - DOMESTIC ROOTS OF SOVIET FOREIGN-POLICY - YANOV,A.” Soviet Studies 30, no. 1 (January 1, 1978): 136–38.Link to Item
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DEWHIRST, M. “DISSENT IN USSR - POLITICS, IDEOLOGY, AND PEOPLE - TOKES,RL.” Soviet Studies 30, no. 1 (January 1, 1978): 136–38.Link to Item
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DEWHIRST, M. “DETENTE AND DEMOCRATIC MOVEMENT IN USSR - BARGHOORN,FC.” Soviet Studies 30, no. 1 (January 1, 1978): 136–38.Link to Item
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Dewhirst, M. W., G. L. Stamp, and A. I. Hurvitz. “Idiopathic monoclonal (IgA) gammopathy in a dog.” J Am Vet Med Assoc 170, no. 11 (June 1, 1977): 1313–16.Link to Item
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DEWHIRST, M. “LITSA - ZAMYATIN,E.” Soviet Studies 22, no. 1 (January 1, 1970): 139–40.Link to Item
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DEWHIRST, M. “RUSSIAN WRITERS AND SOCIETY, 1825-1904 - HINGLEY,R.” Soviet Studies 19, no. 4 (January 1, 1968): 597–98.Link to Item
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DEWHIRST, M. “SOVIET RUSSIAN LITERATURE - WRITERS AND PROBLEMS, 1917-1967 - SLONIM,M.” Soviet Studies 19, no. 4 (January 1, 1968): 597–98.Link to Item
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Prescott, D. M., H. C. Charles, H. D. Sostman, R. L. Page, D. E. Thrall, D. Moore, J. R. Oleson, and M. W. Dewhirst. “Manipulation of intra- and extracellular pH in spontaneous canine tumours by use of hyperglycaemia [hyperthermia efficacy improvement].” Int. J. Hyperth. (Uk) 9, no. 5 (n.d.): 745–54.
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Book Sections
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Yuan, H., G. M. Palmer, and M. W. Dewhirst. “Imaging Hypoxia.” In Molecular Imaging: Principles and Practice, 869–95, 2021. https://doi.org/10.1016/B978-0-12-816386-3.00074-0.Full Text
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Dewhirst, M. W., J. Abraham, and B. Viglianti. “Evolution of Thermal Dosimetry for Application of Hyperthermia to Treat Cancer,” 47:397–421, 2015. https://doi.org/10.1016/bs.aiht.2015.09.001.Full Text
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Dewhirst, M., P. R. Stauffer, S. Das, O. I. Craciunescu, and Z. Vujaskovic. “Hyperthermia.” In Clinical Radiation Oncology, 381-398.e6, 2015. https://doi.org/10.1016/B978-0-323-24098-7.00021-6.Full Text
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Dewhirst, M., S. Das, P. Stauffer, O. Craciunescu, Z. Vujaskovic, and D. Thrall. “Hyperthermia.” In Clinical Radiation Oncology: Third Edition, 385–403, 2012. https://doi.org/10.1016/B978-1-4377-1637-5.00021-3.Full Text
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Other Articles
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Oliveira, Tiago R., Paul R. Stauffer, Chen-Ting Lee, Chelsea Landon, Wiguins Etienne, Paolo F. Maccarini, Brant Inman, and Mark W. Dewhirst. “Preclinical Dosimetry of Magnetic Fluid Hyperthermia for Bladder Cancer.” Proc Spie Int Soc Opt Eng, February 26, 2013. https://doi.org/10.1117/12.2005623.Full Text Link to Item
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Conference Papers
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Zhu, C., H. L. Martin, M. Li, B. Crouch, A. F. Martinez, G. M. Palmer, M. W. Dewhirst, and N. Ramanujam. “Non-invasive, simultaneous quantification of vascular oxygenation, glucose uptake and mitochondria membrane potential in a flank tumor model.” In Optics Infobase Conference Papers, Vol. Part F91-TRANSLATIONAL 2018, 2018. https://doi.org/10.1364/TRANSLATIONAL.2018.CF2B.2.Full Text
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Oldham, M., S. W. Yoon, J. Adamson, Z. Shrock, V. Tsvankin, P. Fecci, and M. W. Dewhirst. “Enhancing Radiation Therapy Through Cherenkov Light-Activated Phototherapy from Clinical Megavoltage Treatment Beams.” In International Journal of Radiation Oncology*Biology*Physics, 99:S229–30. Elsevier BV, 2017. https://doi.org/10.1016/j.ijrobp.2017.06.564.Full Text
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Fraser, Cassandra, Christopher DeRosa, Scott Seaman, Caroline Kerr, Margaret Daly, Alexander Mathew, Meng Zhuang, et al. “Luminescent boron polymers for biomedical imaging.” In Abstracts of Papers of the American Chemical Society, Vol. 254. AMER CHEMICAL SOC, 2017.Link to Item
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Yoon, S., V. Tsvankin, Z. Shrock, B. Meng, M. Dewhirst, P. Fecci, J. Adamson, and M. Oldham. “A Novel Method to Enhance Standard of Care Radiation Therapy: Cherenkov Light Activated Psoralen (CLAP).” In Medical Physics, 44:2995–96. WILEY, 2017.Link to Item
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Brousell, Steven C., Thomas A. Longo, Joseph J. Fantony, Wiguins Etienne, David Needham, Mark W. Dewhirst, Paolo F. Maccarini, Ivan Spasojevic, and Brant A. Inman. “MP65-08 HEAT-TARGETED DRUG DELIVERY USING THE COMBAT BRS DEVICE FOR TREATING BLADDER CANCER.” In Journal of Urology, Vol. 197. Ovid Technologies (Wolters Kluwer Health), 2017. https://doi.org/10.1016/j.juro.2017.02.2002.Full Text
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Dewhirst, Mark W., Kathleen Ashcraft, and Lee Jones. “Abstract SY22-02: Exercise and cancer progression: Preclinical evidence.” In Experimental and Molecular Therapeutics. American Association for Cancer Research, 2016. https://doi.org/10.1158/1538-7445.am2016-sy22-02.Full Text
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Lee, Chen-Ting, Yingchun Zhou, Kingshuk R. Choudhury, Sharareh Siamakpour Reihani, Mark W. Dewhirst, and Janet K. Horton. “Abstract 1656: Subtype-specific radiation response in human breast cancer and potential therapeutic effect of FAS death receptor modulation.” In Tumor Biology. American Association for Cancer Research, 2016. https://doi.org/10.1158/1538-7445.am2016-1656.Full Text
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Siamakpour-Reihani, Sharareh, Wei Chen, David Corcoran, Chen-Ting Lee, Ying Zhou, Mark W. Dewhirst, Jen-Tsan A. Chi, and Janet K. Horton. “Abstract 1647: Radiation response genome-wide analysis using paired pre and post-radiation FFPE human breast tumor samples.” In Tumor Biology. American Association for Cancer Research, 2016. https://doi.org/10.1158/1538-7445.am2016-1647.Full Text
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Lee, Chen-Ting, Yingchun Zhou, Sharareh Siamakpour-Reihani, Kingshuk R. Choudhury, Mark W. Dewhirst, and Janet K. Horton. “Abstract 3302: Subtype-specific radiation response in a mouse model of human breast cancer.” In Tumor Biology. American Association for Cancer Research, 2015. https://doi.org/10.1158/1538-7445.am2015-3302.Full Text
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Kwon, Do-Yeon, Kyunghye Park, Douglas Weitzel, Sun Hee Lee, Tesia Stephenson, Chen-Ting Lee, Jen-Tsan Chi, et al. “Design, synthesis, and biological evaluation of manassantin analogues for HIF-1 alpha inhibition.” In Abstracts of Papers of the American Chemical Society, Vol. 249. AMER CHEMICAL SOC, 2015.Link to Item
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Lee, Chen-Ting, Aaron Blackley, Chelsea Landon, Ivan Spasojevic, John P. Kirkpatrick, and Mark W. Dewhirst. “Abstract 3774: Hyperthermia treatment overcomes temozolomide resistance in glioma cells by downregulatingMGMTexpression and increasing temozolomide uptake.” In Experimental and Molecular Therapeutics. American Association for Cancer Research, 2014. https://doi.org/10.1158/1538-7445.am2014-3774.Full Text
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Robinson, T. J., J. Chi, and M. Dewhirst. “Hypoxia Induces mRNA 3’UTR Truncation in Multiple Cell Types In Vitro.” In International Journal of Radiation Oncology*Biology*Physics, 90:S824–S824. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.2373.Full Text
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Zhang, M., Q. Qiu, H. Min, Z. Li, D. Cardona, Y. Ma, A. Nichols, et al. “HIF-1α Regulates Radiation Resistance in Primary Sarcomas in a Tumor-Cell Autonomous Mechanism.” In International Journal of Radiation Oncology*Biology*Physics, 90:S772–S772. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2014.05.2235.Full Text
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Fraser, Cassandra L., Christopher DeRosa, Jelena Samonina-Kosicka, William A. Morris, Ziyi Fan, J. N. Demas, Alexander Mathew, et al. “Tuning optical properties of difluoroboron beta-diketonate biomaterials for oxygen sensing.” In Abstracts of Papers of the American Chemical Society, Vol. 248. AMER CHEMICAL SOC, 2014.Link to Item
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Samonina-Kosicka, Jelena, Christopher DeRosa, Christina L. Hofmann, Hansford Hendargo, Mark W. Dewhirst, Gregory M. Palmer, and Cassandra L. Fraser. “Boron nanoparticles for oxygen sensing: Material design, optical properties, and bioimaging.” In Abstracts of Papers of the American Chemical Society, Vol. 248. AMER CHEMICAL SOC, 2014.Link to Item
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Martinez, A. F., S. S. McCachren, M. Lee, H. A. Murphy, N. Rajaram, M. W. Dewhirst, and N. Ramanujam. “Hyperspectral imaging of glucose uptake, mitochondrial membrane potential, and vascular oxygenation differentiates breast cancers with distinct metastatic potential in vivo.” In Optics Infobase Conference Papers, 2014. https://doi.org/10.1364/CANCER.2016.CTh4A.6.Full Text
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DeRosa, Christopher A., Jelena Samonina-Kosicka, Ziyi Fan, Christina L. Hofmann, Gregory M. Palmer, Mark W. Dewhirst, and Cassandra L. Fraser. “Oxygen nanosensors based on dual emissive difluoroboron naphthyl alpha-diketonate polylactides for ratiometric tumor hypoxia imaging.” In Abstracts of Papers of the American Chemical Society, Vol. 247. AMER CHEMICAL SOC, 2014.Link to Item
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Dewhirst, M. W., K. Ashcraft, I. Batinic-Haberle, I. Spasojevic, and D. M. Brizel. “A Novel Mnsod Mimic Widens the Therapeutic Margin by Simultaneously Radioprotecting Normal Tissue and Radiosensitizing Tumor.” In International Journal of Radiation Oncology*Biology*Physics, 88:468–468. Elsevier BV, 2014. https://doi.org/10.1016/j.ijrobp.2013.11.028.Full Text
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Frees, A., N. Rajaram, S. McCachren, A. Vaz, M. Dewhirst, and N. Ramanujam. “Optical monitoring of glucose demand and vascular delivery in a preclinical murine model.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 8947, 2014. https://doi.org/10.1117/12.2040950.Full Text
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Boss, M., J. Somarelli, M. Garcia-Blanco, and M. Dewhirst. “Radiation Induces Epithelial-Mesenchymal Transition in an In Vitro Mammary Carcinoma Tumor Model.” In International Journal of Radiation Oncology*Biology*Physics, 87:S630–31. Elsevier BV, 2013. https://doi.org/10.1016/j.ijrobp.2013.06.1667.Full Text
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Robinson, T. J., and M. Dewhirst. “Detection of Novel Hypoxia-Induced Changes in Alternative mRNA Processing Associated With Clinical Prognosis in Adenocarcinoma of the Lung.” In International Journal of Radiation Oncology*Biology*Physics, 87:S664–S664. Elsevier BV, 2013. https://doi.org/10.1016/j.ijrobp.2013.06.1759.Full Text
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Zhang, Tian, Shiva K. Das, Jeffrey Crawford, Terence Wong, Mark W. Dewhirst, and Gordana Vlahovic. “(62)cuatsm and (62)cuptsm PET is a useful imaging tool for hypoxia and perfusion in lung cancer.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Abern, Michael, Zeljko Vujaskovic, Mark W. Dewhirst, Lan Lan, Oana I. Craciunescu, Paul Stauffer, and Brant Allen Inman. “Phase I clinical trial of external hyperthermia and intravesical mitomycin C to treat BCG-refractory bladder cancer.” In Journal of Clinical Oncology, Vol. 31. AMER SOC CLINICAL ONCOLOGY, 2013.Link to Item
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Betof, Allison S., Lee W. Jones, and Mark W. Dewhirst. “Abstract 364: Exercise slows tumor progression and normalizes tumor vasculature in murine models of breast cancer.” In Tumor Biology. American Association for Cancer Research, 2013. https://doi.org/10.1158/1538-7445.am2013-364.Full Text
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Weitzel, Douglas, Kathleen Ashcraft, Chunlei Liu, Wei Li, Anne Buckley, Ramona Rodriguez, William Wetzel, et al. “RADIOPROTECTION OF BRAIN WHITE MATTER BY THE CATALYTIC MnSOD MIMIC/ANTIOXIDANT, BMX-001.” In Neuro Oncology, 15:5–6. OXFORD UNIV PRESS INC, 2013.Link to Item
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Horton, J. K., D. R. Fels, H. Kung, K. Ashcraft, M. W. Dewhirst, and J. A. Chi. “Gene Expression Response to Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines.” In International Journal of Radiation Oncology*Biology*Physics, 84:S710–S710. Elsevier BV, 2012. https://doi.org/10.1016/j.ijrobp.2012.07.1900.Full Text
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Dewhirst, M., A. Fontanella, G. Palmer, M. Boss, J. Zhang, M. Hadsell, and S. Chang. “TH-A-BRB-04: Vascular Response to Microbeam Radiation Therapy in Vivo Using a Murine Window Chamber Tumor Model.” In Medical Physics, 39:3983–3983. Wiley, 2012. https://doi.org/10.1118/1.4736249.Full Text
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Kennedy, Kelly Marie, and Mark W. Dewhirst. “Cellular responses to lactate in breast cancer.” In Journal of Clinical Oncology, Vol. 30. AMER SOC CLINICAL ONCOLOGY, 2012.Link to Item
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Masko, Elizabeth M., Keith R. Solomon, Nikolaos A. Valilis, Alexis R. Gaines, Michael J. Muehlbauer, Christopher B. Newgard, Mark W. Dewhirst, Salvatore V. Pizzo, and Stephen J. Freedland. “225 THE EFFECTS OF CHOLESTEROL TREATMENT DRUGS ALONE AND IN COMBINATION ON PROSTATE TUMOR XENOGRAFT GROWTH.” In Journal of Urology, Vol. 187. Ovid Technologies (Wolters Kluwer Health), 2012. https://doi.org/10.1016/j.juro.2012.02.279.Full Text
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Secomb, Timothy W., Jonathan P. Alberding, Mark W. Dewhirst, and Axel R. Pries. “Theoretical simulation of angiogenesis and structural adaptation in microvascular networks.” In Faseb Journal, Vol. 26. FEDERATION AMER SOC EXP BIOL, 2012.Link to Item
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Grant, Gerald A., Christy Wilson, Matthew Campbell, Shuqin Li, Peter Humphries, Allan Johnson, Mark Dewhirst, and Darell Bigner. “Reversible Opening of the Blood-Brain Barrier by Targeted Suppression of Claudin 5 To Enhance Drug Delivery into Brain Tumors.” In Annals of Neurology, 72:S144–S144. WILEY-BLACKWELL, 2012.Link to Item
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Fraser, Cassandra L., Guoqing Zhang, Nguyen D. Nguyen, Songpan Xu, Alexander G. Zestos, Gregory M. Palmer, Mark W. Dewhirst, et al. “Luminescent boron b-diketonate biomaterials: Synthesis, properties and applications.” In Abstracts of Papers of the American Chemical Society, Vol. 242. AMER CHEMICAL SOC, 2011.Link to Item
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Chitneni, Satish, Gerald Bida, Mark Dewhirst, and Michael Zalutsky. “A simplified synthesis of the hypoxia imaging agent 2-(2-Nitro-1H-imidazol-1-yl)-N-(2,2,3,3,3-[18F]pentafluoropropyl)-acetamide([18F]EF5).” In Journal of Nuclear Medicine, Vol. 52. SOC NUCLEAR MEDICINE INC, 2011.Link to Item
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Landon, Chelsea D., and Mark W. Dewhirst. “Abstract 5377: A role for Ctr1 in the synergistic interaction between mild hyperthermia and cisplatin treatment.” In Experimental and Molecular Therapeutics. American Association for Cancer Research, 2011. https://doi.org/10.1158/1538-7445.am2011-5377.Full Text
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Grant, Gerald A., Christy Wilson, Matthew Campbell, Peter Humphries, Shuqin Li, Jianjun Li, Allan Johnson, Darell Bigner, and Mark Dewhirst. “REVERSIBLE OPENING OF THE BBB BY TARGETED SUPPRESSION OF CLAUDIN 5 TO ENHANCE DRUG DELIVERY TO BRAIN TUMORS.” In Neuro Oncology, 12:98–98. OXFORD UNIV PRESS INC, 2010.Link to Item
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Hanna, G., G. Palmer, W. Park, J. Herbert, Y. Cao, T. Schroeder, G. Vlahovic, A. Nixon, and M. Dewhirst. “Variation in Microenvironmental Effects and Drug Delivery between Different Classes of Antiangiogenic Drugs.” In International Journal of Radiation Oncology*Biology*Physics, 78:S164–65. Elsevier BV, 2010. https://doi.org/10.1016/j.ijrobp.2010.07.405.Full Text
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Vishwanath, K., M. Dewhirst, J. Oleson, and N. Ramanujam. “Longitudinal Monitoring of Functional Changes in Irradiated Head and Neck Tumors using Optical Spectroscopy.” In International Journal of Radiation Oncology*Biology*Physics, 78:S118–S118. Elsevier BV, 2010. https://doi.org/10.1016/j.ijrobp.2010.07.300.Full Text
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Sonveaux, P., F. Vegran, M. Dewhirst, and O. Feron. “TARGETING LACTATE EXCHANGES IN TUMOURS: FROM BASIC CHARACTERIZATION TO NEW THERAPEUTIC APPLICATIONS.” In Radiotherapy and Oncology, 96:S57–S57. ELSEVIER IRELAND LTD, 2010.Link to Item
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Sonveaux, P., M. W. Dewhirst, and O. Feron. “39 Targeting the lactate transporter monocarboxylate transporter 1 constitutes a new therapeutic modality that disrupts a fundamental metabolic symbiosis in tumours.” In European Journal of Cancer Supplements, 8:10–10. Elsevier BV, 2010. https://doi.org/10.1016/s1359-6349(10)70848-x.Full Text
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Vujaskovic, Z., O. I. Craciunescu, P. Stauffer, M. Carroll, L. Lan, M. Dewhirst, and B. A. Inman. “Pilot study of external hyperthermia and intravesical mitomycin-C to treat recurrent biadder cancer after failed standard therapy.” In Journal of Clinical Oncology, Vol. 28. AMER SOC CLINICAL ONCOLOGY, 2010.Link to Item
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Antonelli, Jodi, Lee Jones, Jean-Alfred Thomas, Elizabeth Masko, Jessica Lloyd, Susan Poulton, Tameika Phillips, et al. “89 EFFECT OF VOLUNTARY WHEEL RUNNING ON GROWTH OF PROSTATE CANCER IN IMMUNOCOMPROMISED AND IMMUNOCOMPETENT MOUSE MODELS.” In Journal of Urology, Vol. 183. Ovid Technologies (Wolters Kluwer Health), 2010. https://doi.org/10.1016/j.juro.2010.02.138.Full Text
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Sonveaux, P., F. Végran, M. Dewhirst, and O. Feron. “12 oral: Targeting the Lactate Transporter MCT1 Induces A Metabolic Rearrangement that Radiosensitizes Tumors.” In Radiotherapy and Oncology, 94:S7–S7. Elsevier BV, 2010. https://doi.org/10.1016/s0167-8140(15)34431-5.Full Text
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Oldham, M., A. Thomas, T. Schroeder, A. Fontanella, and M. Dewhirst. “TU‐E‐201C‐06: Imaging the Biological Structure and Characteristics of Model Tumors Using Optical Computed Transmission and Emission Tomography.” In Medical Physics, 37:3405, 2010. https://doi.org/10.1118/1.3469308.Full Text
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Secomb, Timothy W., Mark W. Dewhirst, and Axel R. Pries. “Growth and Structural Adaptation of Blood Vessels in Normal and Tumor Tissues.” In New Perspectives in Mathematical Biology, edited by S. Sivaloganathan, 57:21–35. AMER MATHEMATICAL SOC, 2010.Link to Item
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Hanna, Gabi, Tina Tailor, Greg Palmer, Joseph Herbert, Gordana Vlahovic, and Mark Dewhirst. “Abstract A10: Antiangiogenic therapy (VEGF-R1–3 and PDGFR inhibitor) increases tumor hemoglobin saturation and decreases interstitial pressure, and microvessel density.” In Molecular Cancer Therapeutics, 8:A10–A10. American Association for Cancer Research (AACR), 2009. https://doi.org/10.1158/1535-7163.targ-09-a10.Full Text
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Tailor, Tina D., Gabi Hanna, Pavel S. Yarmolenko, and Mark W. Dewhirst. “Abstract A7: Targeting the tumor microenvironment via inhibition of VEGF and PDGF to improve liposomal drug delivery in human non-small cell lung cancer xenografts.” In Molecular Cancer Therapeutics, 8:A7–A7. American Association for Cancer Research (AACR), 2009. https://doi.org/10.1158/1535-7163.targ-09-a7.Full Text
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Zagar, T. M., K. Higgins, M. Edward, Z. Vujaskovic, M. Dewhirst, R. Clough, and E. Jones. “Long-term Palliation of Breast Cancer Chestwall Recurrence with Radiation Therapy, Hyperthermia, and Chemotherapy.” In International Journal of Radiation Oncology*Biology*Physics, 75:S505–S505. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.1152.Full Text
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Brizel, D. M., D. S. Yoo, N. Ready, J. P. Kirkpatrick, M. W. Dewhirst, R. L. Scher, E. Cleland, J. MacFall, D. Barboriak, and O. Craciunescu. “Synchronous Chemoradiation and Multiple Targeted Drugs for Advanced Head and Neck Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 75:S175–76. Elsevier BV, 2009. https://doi.org/10.1016/j.ijrobp.2009.07.409.Full Text
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Sonveaux, Pierre, Frederique Vegran, Thies Schroeder, Olivier Feron, and Mark Dewhirst. “Role of lactate as a fuel in a unique microenvironmentally controlled metabolic symbiont.” In Cancer Research, Vol. 69. AMER ASSOC CANCER RESEARCH, 2009.Link to Item
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Antonelli, Jodi, Lee W. Jones, Susan Poulton, Tamieka Phillips, Mark Dewhirst, and Stephen J. Freedland. “EFFECTS OF EXERCISE ON PROSTATE CANCER GROWTH IN A MOUSE MODEL.” In Journal of Urology, 181:48–48. Ovid Technologies (Wolters Kluwer Health), 2009. https://doi.org/10.1016/s0022-5347(09)60147-6.Full Text
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Skala, M., A. Fontanella, H. Hendargo, M. Dewhirst, and J. Izatt. “Combined hyperspectral and optical coherence tomography microscope for non-invasive hemodynamic imaging.” In Optics Infobase Conference Papers, 2009. https://doi.org/10.1364/ntm.2009.ntub2.Full Text
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Ye, Xiaodong, Diane Fels, Casey Dedeugd, Mark W. Dewhirst, Kam Leong, and Ines Batinic-Haberle. “The in vitro Cytotoxic Effects of Mn(III) Alkylpyridylporphyrin/ascorbate system on Four Tumor Cell Lines.” In Free Radical Biology and Medicine, 47:S136–S136. ELSEVIER SCIENCE INC, 2009.Link to Item
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Craciunescu, O., J. Macfall, B. Soher, P. Stauffer, P. Maccarini, E. Jones, N. Larrier, et al. “WE‐C‐BRC‐02: Combined Dynamic Contrast Enhanced Magnetic Resonance Imaging (DCE‐MRI) and Magnetic Resonance Thermal Imaging (MRTI) for Optimal Hyperthermia Treatment of Advanced Extremity Sarcomas: Fifteen Patients Update.” In Medical Physics, 36:2760, 2009. https://doi.org/10.1118/1.3182470.Full Text
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Cornelissen, A., M. Hoepfner, L. Ulm, B. Styp-Rekowska, T. Secomb, M. Dewhirst, and A. R. Pries. “Defective vascular adaptation accounts for structural and functional heterogeneity of tumor microvascular networks.” In Onkologie, 31:58–58. KARGER, 2008.Link to Item
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Cheng, K., Z. Li, P. Stauffer, W. Joines, M. Dewhirst, and S. Das. “SU‐GG‐T‐366: Hyperthermia Treatment for a Patient with Two Shank Sarcomas Treated by a Fast Pre‐Treatment Optimization Method.” In Medical Physics, 35:2809, 2008. https://doi.org/10.1118/1.2962118.Full Text
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Kim, E., J. Bowsher, H. Sakhalkar, M. Dewhirst, and M. Oldham. “TU‐FF‐A4‐03: Improving the Accuracy of Optical‐Emission‐CT Imaging Through Application of a Non‐Uniform Attenuation Correction.” In Medical Physics, 35:2923, 2008. https://doi.org/10.1118/1.2962658.Full Text
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Cheng, K., V. Stakhursky, O. Craciunescu, P. Stauffer, M. Dewhirst, and S. Das. “SU‐GG‐T‐367: Fast Hyperthermia Temperature Optimization for Pelvic Carcinoma Patient Treated in Sigma‐Eye Applicator.” In Medical Physics, 35:2809–10, 2008. https://doi.org/10.1118/1.2962119.Full Text
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Salahuddin, F., Z. Rabbani, P. Yarmolenko, I. Batinic-Haberle, B. Thrasher, B. Gauter-Fleckenstein, M. Dewhirst, M. Anscher, and Z. Vujaskovic. “High Dose of Low Molecular Weight Catalytic Metalloporphyrin Antioxidant AEOL 10150 Protects Lungs From Fractionated Radiation.” In International Journal of Radiation Oncology*Biology*Physics, 69:S484–S484. Elsevier BV, 2007. https://doi.org/10.1016/j.ijrobp.2007.07.1688.Full Text
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Jones, E. L., Z. Vujaskovic, O. Craciunescu, L. R. Prosnitz, L. Havrilesky, A. Secord, P. Stauffer, and M. W. Dewhirst. “International Phase III Trial of Chemoradiotherapy ± Hyperthermia for Locally Advanced Cervix Cancer: Interim Update on Toxicities.” In International Journal of Radiation Oncology*Biology*Physics, 69:S392–93. Elsevier BV, 2007. https://doi.org/10.1016/j.ijrobp.2007.07.1513.Full Text
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Blackwell, K. L., J. Chi, C. Sidor, P. Burke, T. LaVallee, H. S. Shaw, V. Liotcheva, et al. “The effects of paclitaxel (PTX) and 2-methoxyestradiol (2-ME2) on tumor oxygenation and HIF-1 alpha in breast cancer.” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.Link to Item
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Vlahovic, G., T. L. Foster, C. H. Andrews, J. E. Herndon, T. Sporn, M. J. Kelley, M. W. Dewhirst, and Z. Vujaskovic. “Phase I dose escalation, toxicity and dynamic contrast-enhanced (DCE) MRI imaging biomarker study of first line treatment with imatinib (I) and cisplatin (C) plus docetaxel (D) in patients with advanced non-small cell lung cancer (NSCLC).” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.Link to Item
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Yan, B., H. Wang, Z. N. Rabbani, M. W. Dewhirst, and C. Li. “Tumor necrosis factor-alpha is a potent endogenous mutagen that promotes cellular transformation.” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.Link to Item
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Jones, E. L., Z. Vujaskovic, and M. W. Dewhirst. “Hyperthermia in the treatment of gynecologic cancer: A review of the cervix cancer experience.” In Strahlentherapie Und Onkologie, 183:152–152. URBAN & VOGEL, 2007.Link to Item
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Arabe, Omar A., Paolo F. Maccarini, Ellen L. Jones, George Hanna, Thaddeus V. Samulski, Mark W. Dewhirst, Donald E. Thrall, and Paul R. Stauffer. “A 400 MHz hyperthermia system using rotating spiral antennas for uniform treatment of large superficial and sub-surface tumors.” In 2007 Ieee/Mtt S International Microwave Symposium Digest, Vols 1 6, 1329-+. IEEE, 2007.Link to Item
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Mcguire, S., S. Zhou, L. Marks, M. Dewhirst, F. Yin, and S. Das. “TH‐E‐M100E‐03: Optimizing the Methodology for Incorporating SPECT‐Guidance to Reduce Intensity Modulated Radiation Therapy (IMRT) Dose to Functioning Lung.” In Medical Physics, 34:2654, 2007. https://doi.org/10.1118/1.2761773.Full Text
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Sonveaux, P., O. Feron, T. J. McMahon, J. S. Stamler, and M. W. Dewhirst. “C34. Oxygen regulation of tumor perfusion unravels the central pressor activity of cell-free human S-nitrosohemoglobin.” In Nitric Oxide, 17:28–28. Elsevier BV, 2007. https://doi.org/10.1016/j.niox.2007.09.079.Full Text
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Needham, D., A. Wright, J. Tong, M. W. Dewhirst, A. Ponce, and F. Yuan. “Mapping engineering onto biology at the nanoscale: nature's encapsulation technologies as bioinspiration for nano-scale anti-tumor drug delivery.” In Nanomedicine: Nanotechnology, Biology and Medicine, 2:292–93. Elsevier BV, 2006. https://doi.org/10.1016/j.nano.2006.10.077.Full Text
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Arcasoy, Murat O., Matthew E. Hardee, Xiaohong Jiang, and Mark W. Dewhirst. “Role of erythropoietin as an angiogenic factor and target in cancer.” In Blood, 108:127A-127A. AMER SOC HEMATOLOGY, 2006.Link to Item
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McGuire, S. M., S. Zhou, L. B. Marks, M. Dewhirst, F. Yin, and S. K. Das. “2808.” In International Journal of Radiation Oncology*Biology*Physics, 66:S663–S663. Elsevier BV, 2006. https://doi.org/10.1016/j.ijrobp.2006.07.1226.Full Text
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Sakhalkar, H. S., T. Oliver, M. Dewhirst, and M. Oldham. “32.” In International Journal of Radiation Oncology*Biology*Physics, 66:S18–19. Elsevier BV, 2006. https://doi.org/10.1016/j.ijrobp.2006.07.1326.Full Text
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Yoo, D. S., Z. Vujaskovic, L. R. Prosnitz, L. B. Marks, K. L. Blackwell, M. W. Dewhirst, and E. L. Jones. “2026.” In International Journal of Radiation Oncology*Biology*Physics, 66:S223–24. Elsevier BV, 2006. https://doi.org/10.1016/j.ijrobp.2006.07.428.Full Text
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Yan, B., H. Wang, J. S. Bedford, M. W. Dewhirst, and C. Li. “A novel role of DNA fragmentation factor as a tumor suppressor through maintaining genomic stability.” In Journal of Clinical Oncology, 24:546S-546S. AMER SOC CLINICAL ONCOLOGY, 2006.Link to Item
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Dreher, Matthew R., Wenge Liu, Michael R. Zalutsky, Mark W. Dewhirst, and Ashutosh Chilkoti. “Targeted drug delivery to solid tumors using thermally responsive elastin-like polypeptide macromolecular drug carriers.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.Link to Item
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Huang, Julie H., L Isabel Cardenas-Navia, Charles C. Caldwell, Michail Sitkovsky, Mark W. Dewhirst, and Michael L. Dustin. “Requirements for T lymphocyte migration in explanted lymph nodes.” In Journal of Immunology, 176:S44–45. AMER ASSOC IMMUNOLOGISTS, 2006.Link to Item
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McPhatter, Lisa A., Zahid N. Rabbani, Pierre Sonveaux, Matthew E. Hardee, Zeljko Vujaskovic, Herbert I. Hurwitz, and Mark W. Dewhirst. “Combination therapy of bevacizumab with rapamycin in antitumor activity.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.Link to Item
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Oltean, Sebastian, Brian Sorg, Todd Albrecht, Vivian Bonano, Robert Brazas, Mark W. Dewhirst, and Mariano A. Garcia-Blanco. “Imaging alternative splicing in prostate tumors reveals mesenchymal-epithelial transitions in vivo.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.Link to Item
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Vlahovic, Gordana, Zahid Rabbani, Ivan Spasojevic, Larisa Zgonjanin, Mark W. Dewhirst, and Zeljko Vujaskovic. “Treatment with gleevec in NSCLC xenografts decreases proliferative capillary index and improves drug delivery.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.Link to Item
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Yan, Bin, Huili Wang, Mark W. Dewhirst, Joel S. Bedford, and Chuan-Yuan Li. “A novel role of DNA fragmentation factor as a tumor suppressor through maintaining genetic stability.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.Link to Item
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Baras, Aris I., Ian Cushman, Yiting Cao, Herbert K. Lyerly, Mark Dewhirst, Patrick Casey, and Gayathri R. Devi. “Development of cellular models and small GTPases-targeted therapeutics for inflammatory breast cancer.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.Link to Item
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Singh, Simendra, Gamil Antoun, Bartley Adams, Gayathri Devi, Neil Spector, Kim Blackwell, Mark Dewhirst, Herbert K. Lyerly, and Francis Ali-Osman. “Pharmacogenetics, molecular correlates and multiparameter high throughput evaluation of the response of inflamatory breast cancer cells to anticancer agents.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.Link to Item
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Bondurant, Bruce, Bob Sutherland, Christopher J. Bondurant, and Mark W. Dewhirst. “Radiation sensitive liposomes.” In Abstracts of Papers of the American Chemical Society, Vol. 231. AMER CHEMICAL SOC, 2006.Link to Item
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Brizel, D., J. Kirkpatrick, and M. Dewhirst. “4 Concurrent angiogenic and EGFR blockade in conjunction with curative intent chemoradiation for locally advanced head and neck cancer.” In Radiotherapy and Oncology, 78:S2–S2. Elsevier BV, 2006. https://doi.org/10.1016/s0167-8140(06)80498-6.Full Text
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Oldham, M., Y. Wang, Z. Vujaskovic, and M. Dewhirst. “164 Optical-computed-and emission tomography: A new imaging modality for cancer research.” In Radiotherapy and Oncology, 78:S55–56. Elsevier BV, 2006. https://doi.org/10.1016/s0167-8140(06)80643-2.Full Text
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Mcguire, S., S. Zhou, L. Marks, M. Dewhirst, F. Yin, and S. Das. “TH‐C‐224C‐09: Using SPECT‐Guidance to Reduce Intensity Modulated Radiation Therapy (IMRT) Dose to Functioning Lung.” In Medical Physics, 33:2275, 2006. https://doi.org/10.1118/1.2241882.Full Text
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Oldham, M., H. Sakhalkar, T. Oliver, and M. Dewhirst. “WE‐D‐330A‐02: Optical‐Computed‐and Emmission Tomography: Applications in Cancer Research.” In Medical Physics, 33:2239–40, 2006. https://doi.org/10.1118/1.2241740.Full Text
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Rabbani, Z. N., J. P. Kirkpatrick, F. K. Salahuddin, R. C. Bentley, A. A. Secord, C. S. Greenberg, L. J. Havrilesky, Z. Vujaskovic, E. Jones, and M. W. Dewhirst. “Tissue transglutaminase expression in early-stage cervical cancer.” In International Journal of Radiation Oncology Biology Physics, 66:S167–S167, 2006. https://doi.org/10.1016/j.ijrobp.2006.07.331.Full Text Link to Item
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Sakhalkar, H., Y. Wang, T. Oliver, M. Dewhirst, and M. Oldham. “WE‐D‐330A‐01: 3D Optical Imaging of Tumor Microvasculature and Viable Cell Distribution.” In Medical Physics, 33:2239, 2006. https://doi.org/10.1118/1.2241739.Full Text
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Craciunescu, O., T. Raidy, D. Brizel, K. Blackwell, Z. Vujaskovic, T. Wong, E. Jones, N. Larrier, J. Macfall, and M. Dewhirst. “SU‐FF‐J‐125: Therapy Assessment Using a Full Time Point (fTP) Pharmacokinetic Analysis of Dynamic Contrast‐Enhanced Magnetic Resonance Imaging (DCE‐MRI): Role of Region of Interest (ROI) Selection in Three Tumor Sites.” In Medical Physics, 33:2049, 2006. https://doi.org/10.1118/1.2240901.Full Text
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Zennadi, R., B. J. Moeller, M. W. Dewhirst, and M. J. Telen. “Role of LW and AKAP79 in beta-adrenergic receptor signaling-induced sickle red blood cell adhesion.” In Blood, 106:889A-889A. AMER SOC HEMATOLOGY, 2005.Link to Item
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Driehuys, B., T. Raidy, J. Pollaro, A. Johnson, M. Dewhirst, L. Marks, and Z. Vujaskovic. “Hyperpolarized 129Xe MRI for Functional Assessment of Radiation-Induced Lung Injury.” In International Journal of Radiation Oncology*Biology*Physics, 63:S460–61. Elsevier BV, 2005. https://doi.org/10.1016/j.ijrobp.2005.07.784.Full Text
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Jones, E. L., J. R. Oleson, L. R. Prosnitz, T. V. Samulski, Z. Vujaskovic, D. Yu, L. L. Sanders, and M. W. Dewhirst. “A Randomized Trial of Hyperthermia and Radiation for Superficial Tumors.” In International Journal of Radiation Oncology*Biology*Physics, 63:S190–S190. Elsevier BV, 2005. https://doi.org/10.1016/j.ijrobp.2005.07.330.Full Text
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Meyer, J., Z. Rabbani, R. Bentley, L. Havrilesky, A. Secord, J. Kirkpatrick, M. Dewhirst, E. Jones, and Z. Vujaskovic. “High Levels of Immunoexpression of the Endothelial Cell Proliferation Marker CD105 Predict for Local Failure in Early-Stage Cervical Cancer.” In International Journal of Radiation Oncology*Biology*Physics, 63:S216–17. Elsevier BV, 2005. https://doi.org/10.1016/j.ijrobp.2005.07.372.Full Text
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Oldham, M., T. Oliver, and M. Dewhirst. “A Novel Method of Imaging Unperturbed Tumor Vasculature in 3D.” In International Journal of Radiation Oncology*Biology*Physics, 63:S134–S134. Elsevier BV, 2005. https://doi.org/10.1016/j.ijrobp.2005.07.228.Full Text
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Rabbani, Z. N., I. Batinic-Haberle, S. Poulton, M. S. Anscher, M. W. Dewhirst, and Z. Vujaskovic. “Long-Term Administration of a Small Molecular Weight Catalytic Metalloporphyrin Antioxidant AEOL 10150 Protects Lungs From Radiation-Induced Injury.” In International Journal of Radiation Oncology*Biology*Physics, 63:S84–S84. Elsevier BV, 2005. https://doi.org/10.1016/j.ijrobp.2005.07.145.Full Text
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Vujaskovic, Z., L. Chen, A. Thrasher, Z. N. Rabbani, M. W. Dewhirst, and M. S. Anscher. “Temporal Onset of Chronic Oxidative Stress and Hypoxia After Pulmonary Irradiation Is Associated with Profibrogenic and Proangiogenic Cytokine Production.” In International Journal of Radiation Oncology*Biology*Physics, 63:S134–35. Elsevier BV, 2005. https://doi.org/10.1016/j.ijrobp.2005.07.229.Full Text
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Yuan, H., Z. Wang, T. Schroeder, J. E. Bowsher, L. W. Hedlund, F. Yin, and M. W. Dewhirst. “(64) Cu-ATSM microPET Imaging of Tumor Hypoxia in Mammary Tumor Model: Compartmental Modeling and Immunohistochemistry Analysis.” In International Journal of Radiation Oncology*Biology*Physics, 63:S251–S251. Elsevier BV, 2005. https://doi.org/10.1016/j.ijrobp.2005.07.427.Full Text
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Vlahovic, G., Z. Rabbani, M. Dewhirst, and Z. Vujaksovic. “O-196 Treatment with gleevec in non-small cell lung cancer isassociated with decrease of PDGF-rb and VEGF expression, decrease in IFP and improvement of tumor oxygenation.” In Lung Cancer, 49:S65–66. Elsevier BV, 2005. https://doi.org/10.1016/s0169-5002(05)80331-9.Full Text
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Kim, S. J., Z. N. Rabbani, R. T. Vollmer, E. G. Schreiber, M. W. Dewhirst, Z. Vujaskovic, and M. J. Kelley. “Expression of phosphorylated epidermal growth factor receptor (p-EGFR) in early stage non-small cell lung cancer: its relationship with overexpression of EGFR and cyclooxygenase-2 (COX-2), and survival.” In Journal of Clinical Oncology, 23:864S-864S. AMER SOC CLINICAL ONCOLOGY, 2005.Link to Item
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Kelly, P., B. Moeller, M. Booden, T. Fields, M. Dewhirst, C. Der, and P. Casey. “The role of the G12 family of hetereotrimeric G-proteins in breast cancer metastasis.” In Faseb Journal, 19:A519–A519. FEDERATION AMER SOC EXP BIOL, 2005.Link to Item
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Batinic-Haberle, I., I. Spasojevic, R. D. Stevens, B. Bondurant, A. Okado-Matsumoto, I. Fridovich, and M. W. Dewhirst. “New Mn(III) porphyrins with high superoxide disproportionating ability.” In Free Radical Biology and Medicine, 39:S19–S19. ELSEVIER SCIENCE INC, 2005.Link to Item
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Oldham, M., T. Oliver, and M. Dewhirst. “WE‐D‐I‐609‐05: Optical Imaging of Tumor Microvasculature in 3D.” In Medical Physics, 32:2134, 2005. https://doi.org/10.1118/1.1998550.Full Text
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Wang, Z., H. Yuan, C. Willett, M. Dewhirst, and F. Yin. “SU‐EE‐A4‐04: Compartment Modeling Analysis of Cu‐ATSM Dynamic PET Images.” In Medical Physics, 32:1901, 2005. https://doi.org/10.1118/1.1997468.Full Text
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Craciunescu, O., K. Blackwell, T. Wong, E. Rosen, T. Raidy, E. Jones, Z. Vujaskovic, et al. “SU‐EE‐A2‐06: Non‐Contact, Non‐Invasive Breast Thermography Has Potential to Evaluate Treatment Response in Breast Cancer Patients.” In Medical Physics, 32:1898, 2005. https://doi.org/10.1118/1.1997458.Full Text
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Bowsher, J. E., H. Yuan, L. W. Hedlund, T. G. Turkington, G. Akabani, A. Badea, W. C. Kurylo, et al. “Utilizing MRI information to estimate F18-FDG distributions in rat flank tumors.” In Ieee Nuclear Science Symposium Conference Record, 4:2488–92, 2004.
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Zennadi, Rahima, Benjamin J. Moeller, Erin J. Whalen, Mark W. Dewhirst, and Marilyn J. Telen. “Epinephrine-Induced Sickle Red Cell Adhesion and Vaso-Occlusion In Vivo Is Inhibited by the β-Adrenoceptor Blocker Propranolol.” In Blood, 104:364–364. American Society of Hematology, 2004. https://doi.org/10.1182/blood.v104.11.364.364.Full Text
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VIGLIANTI, B., C. MICHELICH, S. ABRAHAM, O. COLVIN, P. YARMOLENKO, J. MACFALL, M. BALLY, and M. DEWHIRST. “Chemodosimetry of in-vivo tumor liposome/drug concentration using MRI.” In International Journal of Radiation Oncologybiologyphysics, 60:S225–26. Elsevier BV, 2004. https://doi.org/10.1016/s0360-3016(04)01239-8.Full Text
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Hardee, M. E., J. P. Kirkpatrick, S. Snyder, S. Shan, Z. Vujaskovic, Z. N. Rabbani, M. W. Dewhirst, and K. L. Blackwell. “Erythropoietin (EPO) has no direct effect on tumor growth or angiogenesis in animal models.” In Journal of Clinical Oncology, 22:842S-842S. AMER SOC CLINICAL ONCOLOGY, 2004.Link to Item
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Vujaskovic, Z., E. Jones, E. Rosen, Z. Rabbani, S. Kim, V. Liotcheva, M. Dewhirst, T. Samulski, L. Prosnitz, and K. Blackwell. “High degree of correlation between in vivo tumor oxygenation measurements and carbonic anhydrase IX tissue staining in operable human breast cancer.” In Journal of Clinical Oncology, 22:46S-46S. AMER SOC CLINICAL ONCOLOGY, 2004.Link to Item
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Dhawan, M., D. Price, D. Trump, P. Kanter, N. Shore, D. Needham, and M. Dewhirst. “New drug delivery approach for the treatment of prostate cancer (preclinical results and phase I study results).” In Journal of Clinical Oncology, 22:421S-421S. AMER SOC CLINICAL ONCOLOGY, 2004.Link to Item
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Abdel-Wahab, O. I., E. Grubbs, T. Y. Cheng, B. Viglianti, T. Ueno, S. Curtiss, S. K. Pruitt, M. W. Dewhirst, and D. S. Tyler. “Role of hyperthermia in regional alkylating agent chemotherapy.” In Annals of Surgical Oncology, 11:S79–80. Springer Science and Business Media LLC, 2004. https://doi.org/10.1007/bf02524061.Full Text
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Sarraf-Yazdi, S., J. Mi, C. Kontos, M. Dewhirst, and B. Clary. “In vivo expression of an adenoviral vector encoding soluble tie2 inhibits metastatic hepatic tumor growth.” In Annals of Surgical Oncology, 11:S56–S56. Springer Science and Business Media LLC, 2004. https://doi.org/10.1007/bf02523984.Full Text
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Blackwell, K. L., H. Dressman, J. Olson, E. Rosen, P. K. Marcom, V. Liotcheva, E. Jones, et al. “Molecular signatures that predict response to anthracycline-taxane based neoadjuvant chemotherapy.” In Breast Cancer Research and Treatment, 88:S22–S22. SPRINGER, 2004.Link to Item
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Moeller, B. J., I. Batinic-Haberle, I. Spasojevic, Z. N. Rabbani, M. S. Anscher, Z. Vujaskovic, and M. W. Dewhirst. “MNTE-2-PYP5+ enhances tumor radiosensitivity by sensitizing tumor vasculature.” In Free Radical Biology and Medicine, 37:S168–S168. PERGAMON-ELSEVIER SCIENCE LTD, 2004.Link to Item
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Prohaska, S., M. Dreher, M. W. Dewhirst, A. Chilkoti, A. R. Pries, M. Westerhoff, and A. J. M. Cornelissen. “3-D reconstruction of tumor vascular networks.” In Journal of Vascular Research, 41:463–463. KARGER, 2004.Link to Item
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Siddiqui, F., P. R. Avery, S. M. LaRue, M. L. Hauck, M. W. Dewhirst, C. Li, and R. L. Ullrich. “A phase I hyperthermia-induced interleukin-12 gene-therapy trial in a spontaneously arising feline soft tissue sarcoma model.” In International Journal of Radiation Oncology Biology Physics, 60:S577–S577. ELSEVIER SCIENCE INC, 2004.Link to Item
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Tuttle, S., M. Dewhirst, R. Richardson, S. Owen, and J. Biaglow. “Effects of 5-androsten-3fo-ol-17-one and related steroids on respiration in R3230 breast cancer cells; implications for PDT and IR.” In Free Radical Biology and Medicine, 37:S176–S176. PERGAMON-ELSEVIER SCIENCE LTD, 2004.Link to Item
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Ward, E. R., L. Hedlund, W. Kurylo, B. Viglianti, C. Wheeler, M. Anscher, M. Dewhirst, L. Marks, and Z. Vujaskovic. “Hyperpolarized helium MRI assessment of the spatial heterogeneity in lung function with potential relationship to radiation response.” In International Journal of Radiation Oncology Biology Physics, 60:S224–25. ELSEVIER SCIENCE INC, 2004.Link to Item
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Craciunescu, O. I., K. L. Blackwell, E. L. Jones, Z. Vujaskovic, E. L. Rosen, T. Z. Wong, J. R. MacFall, et al. “Contrast-enhanced magnetic resonance imaging (CE-MRI) parameters have predictive value in estimating response of locally advanced breast cancer (LABC) patients to neoadjuvant (NA) chemotherapy (CT) and hyperthermia (HT).” In Breast Cancer Research and Treatment, 88:S18–19. SPRINGER, 2004.Link to Item
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Zennadi, R., B. J. Moeller, Q. Zen, M. W. Dewhirst, and M. J. Telen. “In vitro exposure to epinephrine causes in vivo adhesion of human sickle red blood cells to vascular endothelium in nude mice: A new model for studying vaso-occlusion.” In Blood, 102:261A-261A. AMER SOC HEMATOLOGY, 2003.Link to Item
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Das, S., M. Bell, S. Zhou, M. Miften, M. Munley, C. Whiddon, O. Craciunescu, et al. “Feasibility of functional image-guided radiotherapy evaluated using a novel heuristic fluence modulation algorithm.” In Medical Physics, 30:1335–1335. AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS, 2003.Link to Item
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Monahan, P. E., J. E. Rabinowitz, J. R. Elia, Y. Tang, V. Ntziachristo, B. S. Sorg, M. W. Dewhirst, R. Weissleder, and R. J. Samulski. “Serial real-time luminescence imaging profiles differential kinetics and biodistibution of transgene expression from AAV serotype 1-5 vectors following adult and neonatal gene transfer.” In Molecular Therapy, 7:S158–59. ACADEMIC PRESS INC ELSEVIER SCIENCE, 2003.Link to Item
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Sarraf-Yazdi, Shiva, Jing Mi, Mark Dewhirst, and Bryan Clary. “Comparative inhibition of angiostatin and endostatin in the treatment of hepatic micrometastases.” In Gastroenterology, 124:A806–A806. Elsevier BV, 2003. https://doi.org/10.1016/s0016-5085(03)84066-0.Full Text
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Blackwell, K. L., M. W. Dewhirst, D. P. McDonnell, H. Dressman, S. A. Snyder, and J. R. Marks. “MTA-1 (metastasis associated protein-1) is upregulated in tamoxifen-resistant breast cancer.” In Breast Cancer Research and Treatment, 82:S88–S88. KLUWER ACADEMIC PUBL, 2003.Link to Item
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Blackwell, K., N. Spector, S. Snyder, J. Marks, L. H. Broadwater, D. McDonnell, M. Dewhirst, W. Xia, and L. H. Liu. “GW572016, a novel dual EGFR/Her-2 small molecule, tyrosine kinase inhibitor induces regression and significant growth delay in tamoxifen-resistant, MCF-7 derived tumors.” In Breast Cancer Research and Treatment, 76:S130–S130. KLUWER ACADEMIC PUBL, 2002.Link to Item
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Monahan, P. E., J. E. Rabinowitz, J. R. Elia, T. Yi, V. Ntziachristo, B. S. Sorg, M. W. Dewhirst, R. Weissleder, and R. J. Samulski. “Gene expression profiling of AAV serotype 1-5 vectors in adult and neonatal animals using in vivo bioluminescence imaging.” In Blood, 100:220A-220A. AMER SOC HEMATOLOGY, 2002.Link to Item
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Viglianti, B. L., S. A. Abraham, J. R. MacFall, M. B. Bally, and M. W. Dewhirst. “In vivo monitoring of real time tissue pharmacokinetics of liposome/drug concentration using MRI.” In Radiology, 225:647–48. RADIOLOGICAL SOC NORTH AMERICA, 2002.Link to Item
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Li, C. Y., and M. W. Dewhirst. “Control of gene therapy by the heat shock promoter.” In Progress in Radio Oncology Vii, Proceedings, edited by H. D. Kogelnik, P. Lukas, and F. Sedlmayer, 577–86. MEDIMOND S R L, 2001.Link to Item
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Lockhart, A. C., R. D. Braun, M. W. Dewhirst, J. S. Humphrey, F. Yuan, J. Grichnick, A. Proia, D. Conway, B. Klitzman, and H. I. Hurwitz. “Wound angiogenesis inhibition as a marker for anti-angiogenic efficacy.” In Faseb Journal, 14:A35–A35. FEDERATION AMER SOC EXP BIOL, 2000.Link to Item
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Dewhirst, M. W., G. Tozer, J. Wilson, G. Rosner, J. Lanzen, A. Kaz, S. Snyder, and J. Stamler. “Modulation of tumour blood flow by nitric oxide.” In Radiation Research, Vol 2, Congress Proceedings, edited by M. Moriaty, M. Edington, C. Mothersill, J. F. Ward, C. Seymour, and R. J. M. Fry, 610–13. ALLEN PRESS INC, 2000.Link to Item
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Dewhirst, M. W., G. Kong, and D. Needham. “Use of hyperthermia to augment liposomal drug delivery to tumours.” In Radiation Research, Vol 2, Congress Proceedings, edited by M. Moriaty, M. Edington, C. Mothersill, J. F. Ward, C. Seymour, and R. J. M. Fry, 853–56. ALLEN PRESS INC, 2000.Link to Item
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Yuan, F., D. Zaharoff, X. Y. Zhang, F. Lohr, M. W. Dewhirst, and C. Y. Li. “Delivery of plasmid DNA through intratumoral infusion and electroporation.” In Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece), 2000-F:125–28, 2000. https://doi.org/10.1115/IMECE2000-2231.Full Text
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Yuan, F., X. Zhang, M. W. Dewhirst, and J. A. Luck. “Pressure and temperature-dependence of the hydraulic conductivity in a fibrosarcoma.” In Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings, 1:91, 1999.
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Craciunescu, O., S. K. Das, and M. W. Dewhirst. “THREE-DIMENSIONAL MICROVASCULAR NETWORKS FRACTAL STRUCTURE: POTENTIAL FOR TISSUE CHARACTERIZATION?” In Asme International Mechanical Engineering Congress and Exposition, Proceedings (Imece), 1999-E:9–13, 1999. https://doi.org/10.1115/IMECE1999-0571.Full Text
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Wilson, D. F., S. A. Vinogradov, A. Mokashi, A. Pastuszko, S. Lahiri, and M. W. Dewhirst. “Tissue oxygen pressure and oxygen sensing by the carotid body.” In Oxygen Homeostasis and Its Dynamics, edited by Y. Ishimura, H. Shimada, and M. Suematsu, 1:377–87. SPRINGER-VERLAG TOKYO, 1998.Link to Item
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Hetiasch, J. M., Z. Haroon, M. W. Dewhirst, J. Marks, D. Iglehart, K. Peters, and C. S. Greenberg. “Tissue transglutaminase is associated with the neovasculature and extracellular matrix of human breast cancer.” In Faseb Journal, Vol. 10, 1996.
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Dewhirst, M. “Clinical implications and techniques for modification of tumor oxygenation.” In 6th World Congress for Microcirculation, edited by K. Messmer and W. M. Kubler, 9–12. MONDUZZI EDITORE, 1996.Link to Item
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Dewhirst, M., E. Ong, B. Smith, S. Evans, T. Secomb, and D. Wilson. “Longitudinal gradients of vascular pO(2) in R3230AC tumor microvessels in dorsal flap window chambers.” In 6th World Congress for Microcirculation, edited by K. Messmer and W. M. Kubler, 343–46. MONDUZZI EDITORE, 1996.Link to Item
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Dewhirst, M., and T. Secomb. “Concepts in tumor oxygen transport.” In 6th World Congress for Microcirculation, edited by K. Messmer and W. M. Kubler, 347–52. MONDUZZI EDITORE, 1996.Link to Item
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Marks, L. B., D. P. Spencer, J. C. Acker, W. Yang, M. A. Avery, R. K. Dodge, and M. W. Dewhirst. “Radiosurgery in rat brain.” In Radiosurgery 1995, edited by D. Kondziolka, 1:308–15. KARGER, 1996.Link to Item
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KLITZMAN, B., N. SCHRADER, R. E. MCLENDON, and M. W. DEWHIRST. “QUANTITATIVE MORPHOLOGY OF RAT CARCINOMA WITH RELEVANCE TO OXYGENATION.” In Faseb Journal, 8:A1046–A1046. FEDERATION AMER SOC EXP BIOL, 1994.Link to Item
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SECOMB, T. W., R. HSU, M. W. DEWHIRST, B. KLITZMAN, and J. F. GROSS. “SIMULATION OF OXYGEN-TRANSPORT TO TUMOR-TISSUE BY MICROVASCULAR NETWORKS.” In Faseb Journal, 6:A2084–A2084. FEDERATION AMER SOC EXP BIOL, 1992.Link to Item
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DEWHIRST, M. W. “MICROVASCULAR CHANGES INDUCED BY RADIATION EXPOSURE - IMPLICATIONS FOR THERAPY.” In Tumor Blood Supply and Metabolic Microenvironment, edited by P. VAUPEL and R. K. JAIN, 20:109–22. GUSTAV FISCHER VERLAG, 1991.Link to Item
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CLEGG, S. T., G. P. RINE, T. V. SAMULSKI, E. D. COBB, C. A. WALLEN, and M. W. DEWHIRST. “RECONSTRUCTION OF A HYPERTHERMIA TEMPERATURE DISTRIBUTION - A COMPARISON OF MODEL PREDICTIONS TO MEASUREMENTS.” In Biofluid Mechanics, 3, edited by D. J. SCHNECK and C. L. LUCAS, 77–86. NEW YORK UNIV PRESS, 1990.Link to Item
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HUGANDER, A., H. I. ROBINS, P. MARTIN, C. SCHMITT, R. PAGE, and M. DEWHIRST. “TEMPERATURE DISTRIBUTION DURING WHOLE-BODY HYPERTHERMIA (WBH) - EXPERIMENTAL STUDIES IN THE DOG.” In Strahlentherapie, 161:537–537. URBAN & VOGEL, 1985.Link to Item
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NASONI, R. L., T. BOWEN, M. DEWHIRST, H. ROTH, and R. PREMOVICH. “THE SPEED OF SOUND AS A FUNCTION OF TEMPERATURE IN MAMMALIAN TISSUE.” In Ieee Transactions on Sonics and Ultrasonics, 28:400–400. IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC, 1981.Link to Item
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Nasoni, R. “In vivo temperature dependence of the speed of sound in mammalian tissue.” In Ultrasonic Imaging, 2:183–183. Elsevier BV, 1980. https://doi.org/10.1016/0161-7346(80)90172-8.Full Text
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