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Desmosdumotin C, a novel cytotoxic principle from Desmos dumosus

Publication ,  Journal Article
Wu, JH; McPhail, AT; Bastow, KF; Shiraki, H; Ito, J; Lee, KH
Published in: Tetrahedron Letters
February 18, 2002

The structure of desmosdumotin C (1), a novel compound isolated from the roots of Desmos dumosus, has been established from spectral data and X-ray crystallographic analysis. Significant and selective in vitro cytotoxicity of 1 was found against bone (HOS), breast (MCF), and ovarian (IA9) cancer cell lines. © 2002 Published by Elsevier Science Ltd.

Duke Scholars

Published In

Tetrahedron Letters

DOI

ISSN

0040-4039

Publication Date

February 18, 2002

Volume

43

Issue

8

Start / End Page

1391 / 1393

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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Wu, J. H., McPhail, A. T., Bastow, K. F., Shiraki, H., Ito, J., & Lee, K. H. (2002). Desmosdumotin C, a novel cytotoxic principle from Desmos dumosus. Tetrahedron Letters, 43(8), 1391–1393. https://doi.org/10.1016/S0040-4039(02)00026-6
Wu, J. H., A. T. McPhail, K. F. Bastow, H. Shiraki, J. Ito, and K. H. Lee. “Desmosdumotin C, a novel cytotoxic principle from Desmos dumosus.” Tetrahedron Letters 43, no. 8 (February 18, 2002): 1391–93. https://doi.org/10.1016/S0040-4039(02)00026-6.
Wu JH, McPhail AT, Bastow KF, Shiraki H, Ito J, Lee KH. Desmosdumotin C, a novel cytotoxic principle from Desmos dumosus. Tetrahedron Letters. 2002 Feb 18;43(8):1391–3.
Wu, J. H., et al. “Desmosdumotin C, a novel cytotoxic principle from Desmos dumosus.” Tetrahedron Letters, vol. 43, no. 8, Feb. 2002, pp. 1391–93. Scopus, doi:10.1016/S0040-4039(02)00026-6.
Wu JH, McPhail AT, Bastow KF, Shiraki H, Ito J, Lee KH. Desmosdumotin C, a novel cytotoxic principle from Desmos dumosus. Tetrahedron Letters. 2002 Feb 18;43(8):1391–1393.
Journal cover image

Published In

Tetrahedron Letters

DOI

ISSN

0040-4039

Publication Date

February 18, 2002

Volume

43

Issue

8

Start / End Page

1391 / 1393

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry