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Radiotherapy of polymorphic reticulosis.

Publication ,  Journal Article
Halperin, EC; Dosoretz, DE; Goodman, M; Wang, CC
Published in: Br J Radiol
September 1982

The term "lethal mid-line granuloma" does not properly reflect current knowledge that several different diseases can produce non-infectious mid-facial destruction. The disorders producing erosion of the upper aerodigestive passages are more accurately classified by clinical and histological criteria as either Wegener's or non-Wegener's causes. The non-Wegener's causes of mid-facial erosion include extranodal lymphoma, idiopathic mid-line granuloma and polymorphic reticulosis. Polymorphic reticulosis (PR) is a rare disease which is histologically identical to lymphomatoid granulomatosis (LG). The term PR has been used to describe LG localized to the upper airways. PR-LG is characterized by a remarkably polymorphic angiocentric mixed cellular infiltrate. The disease is locally invasive, has the potential for distant spread, and can cause fever, sweats and weight loss. When it is localized to the upper airways, PR-LG is potentially controllable by radiation therapy. Local symptoms at other body sites can be successfully palliated by radiation. The clinical presentation of two recent patients with PR-LG is summarized, as well as the radiotherapy employed. The pertinent literature is reviewed.

Duke Scholars

Published In

Br J Radiol

DOI

ISSN

0007-1285

Publication Date

September 1982

Volume

55

Issue

657

Start / End Page

645 / 649

Location

England

Related Subject Headings

  • Terminology as Topic
  • Nuclear Medicine & Medical Imaging
  • Nose Diseases
  • Mouth Diseases
  • Male
  • Lymphomatoid Granulomatosis
  • Humans
  • Granuloma, Lethal Midline
  • Female
  • Adult
 

Citation

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Halperin, E. C., Dosoretz, D. E., Goodman, M., & Wang, C. C. (1982). Radiotherapy of polymorphic reticulosis. Br J Radiol, 55(657), 645–649. https://doi.org/10.1259/0007-1285-55-657-645
Halperin, E. C., D. E. Dosoretz, M. Goodman, and C. C. Wang. “Radiotherapy of polymorphic reticulosis.Br J Radiol 55, no. 657 (September 1982): 645–49. https://doi.org/10.1259/0007-1285-55-657-645.
Halperin EC, Dosoretz DE, Goodman M, Wang CC. Radiotherapy of polymorphic reticulosis. Br J Radiol. 1982 Sep;55(657):645–9.
Halperin, E. C., et al. “Radiotherapy of polymorphic reticulosis.Br J Radiol, vol. 55, no. 657, Sept. 1982, pp. 645–49. Pubmed, doi:10.1259/0007-1285-55-657-645.
Halperin EC, Dosoretz DE, Goodman M, Wang CC. Radiotherapy of polymorphic reticulosis. Br J Radiol. 1982 Sep;55(657):645–649.

Published In

Br J Radiol

DOI

ISSN

0007-1285

Publication Date

September 1982

Volume

55

Issue

657

Start / End Page

645 / 649

Location

England

Related Subject Headings

  • Terminology as Topic
  • Nuclear Medicine & Medical Imaging
  • Nose Diseases
  • Mouth Diseases
  • Male
  • Lymphomatoid Granulomatosis
  • Humans
  • Granuloma, Lethal Midline
  • Female
  • Adult