Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection.
Publication
, Journal Article
Sergueev, DS; Sergueeva, ZA; Shaw, BR
Published in: Nucleosides, nucleotides & nucleic acids
April 2001
Short oligonucleoside boranophosphates containing all four nucleosides were synthesized on solid support using base-unprotected nucleoside H-phosphonate monomers. This strategy avoided irreversible base modifications during the boronation procedure. Structures of the boranophosphate oligomers were confirmed by 1H, 31P, 10B NMR and MS analysis as well as by enzymatic hydrolysis.
Duke Scholars
Published In
Nucleosides, nucleotides & nucleic acids
DOI
EISSN
1532-2335
ISSN
1525-7770
Publication Date
April 2001
Volume
20
Issue
4-7
Start / End Page
789 / 795
Related Subject Headings
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Organophosphonates
- Organic Chemistry
- Oligonucleotides
- Magnetic Resonance Spectroscopy
- Chromatography, High Pressure Liquid
- Boron Compounds
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Sergueev, D. S., Sergueeva, Z. A., & Shaw, B. R. (2001). Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection. Nucleosides, Nucleotides & Nucleic Acids, 20(4–7), 789–795. https://doi.org/10.1081/ncn-100002431
Sergueev, D. S., Z. A. Sergueeva, and B. R. Shaw. “Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection.” Nucleosides, Nucleotides & Nucleic Acids 20, no. 4–7 (April 2001): 789–95. https://doi.org/10.1081/ncn-100002431.
Sergueev DS, Sergueeva ZA, Shaw BR. Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection. Nucleosides, nucleotides & nucleic acids. 2001 Apr;20(4–7):789–95.
Sergueev, D. S., et al. “Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection.” Nucleosides, Nucleotides & Nucleic Acids, vol. 20, no. 4–7, Apr. 2001, pp. 789–95. Epmc, doi:10.1081/ncn-100002431.
Sergueev DS, Sergueeva ZA, Shaw BR. Synthesis of oligonucleoside boranophosphates via an H-phosphonate method without nucleobase protection. Nucleosides, nucleotides & nucleic acids. 2001 Apr;20(4–7):789–795.
Published In
Nucleosides, nucleotides & nucleic acids
DOI
EISSN
1532-2335
ISSN
1525-7770
Publication Date
April 2001
Volume
20
Issue
4-7
Start / End Page
789 / 795
Related Subject Headings
- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Organophosphonates
- Organic Chemistry
- Oligonucleotides
- Magnetic Resonance Spectroscopy
- Chromatography, High Pressure Liquid
- Boron Compounds
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0601 Biochemistry and Cell Biology