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Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica.

Publication ,  Journal Article
Fukamiya, N; Okano, M; Aratani, T; Negoro, K; McPhail, AT; Ju-ichi, M; Lee, KH
Published in: Journal of natural products
May 1986

Two cytotoxic antileukemic alkaloids, the new 1,11-dimethoxycanthin-6-one (3) and the known 11-hydroxycanthin-6-one (1), as well as the known canthin-6-one (2) were isolated from the stem of Brucea antidysenterica. The structures of 1-3 were determined from their spectral data and X-ray analysis of the o-bromobenzoate of 1.

Duke Scholars

Published In

Journal of natural products

DOI

EISSN

1520-6025

ISSN

0163-3864

Publication Date

May 1986

Volume

49

Issue

3

Start / End Page

428 / 434

Related Subject Headings

  • X-Ray Diffraction
  • Medicinal & Biomolecular Chemistry
  • Magnetic Resonance Spectroscopy
  • Leukemia, Experimental
  • Antineoplastic Agents, Phytogenic
  • Animals
  • Alkaloids
  • 4208 Traditional, complementary and integrative medicine
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
 

Citation

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Fukamiya, N., Okano, M., Aratani, T., Negoro, K., McPhail, A. T., Ju-ichi, M., & Lee, K. H. (1986). Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica. Journal of Natural Products, 49(3), 428–434. https://doi.org/10.1021/np50045a007
Fukamiya, N., M. Okano, T. Aratani, K. Negoro, A. T. McPhail, M. Ju-ichi, and K. H. Lee. “Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica.Journal of Natural Products 49, no. 3 (May 1986): 428–34. https://doi.org/10.1021/np50045a007.
Fukamiya N, Okano M, Aratani T, Negoro K, McPhail AT, Ju-ichi M, et al. Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica. Journal of natural products. 1986 May;49(3):428–34.
Fukamiya, N., et al. “Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica.Journal of Natural Products, vol. 49, no. 3, May 1986, pp. 428–34. Epmc, doi:10.1021/np50045a007.
Fukamiya N, Okano M, Aratani T, Negoro K, McPhail AT, Ju-ichi M, Lee KH. Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica. Journal of natural products. 1986 May;49(3):428–434.
Journal cover image

Published In

Journal of natural products

DOI

EISSN

1520-6025

ISSN

0163-3864

Publication Date

May 1986

Volume

49

Issue

3

Start / End Page

428 / 434

Related Subject Headings

  • X-Ray Diffraction
  • Medicinal & Biomolecular Chemistry
  • Magnetic Resonance Spectroscopy
  • Leukemia, Experimental
  • Antineoplastic Agents, Phytogenic
  • Animals
  • Alkaloids
  • 4208 Traditional, complementary and integrative medicine
  • 11 Medical and Health Sciences
  • 06 Biological Sciences