Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. II. Structural determination and total synthesis.
Publication
, Journal Article
Yang, LM; Wu, RY; McPhail, AT; Yokoi, T; Lee, KH
Published in: The Journal of antibiotics
April 1988
The structure of neihumicin, a new antibiotic isolated from the fermentation broth of Micromonospora neihuensis Wu, sp. nov., has been determined as (Z)-3,(Z)-6-dibenzylidene-2-methoxy-3,6-dihydropyrazin-5-one based upon spectral evidence and X-ray crystallographic analysis. Its total synthesis has also been achieved.
Duke Scholars
Published In
The Journal of antibiotics
DOI
EISSN
1881-1469
ISSN
0021-8820
Publication Date
April 1988
Volume
41
Issue
4
Start / End Page
488 / 493
Related Subject Headings
- Pyrazines
- Microbiology
- Medicinal & Biomolecular Chemistry
- Chemistry
- Chemical Phenomena
- Antibiotics, Antineoplastic
- 3214 Pharmacology and pharmaceutical sciences
- 3107 Microbiology
- 1115 Pharmacology and Pharmaceutical Sciences
- 0605 Microbiology
Citation
APA
Chicago
ICMJE
MLA
NLM
Yang, L. M., Wu, R. Y., McPhail, A. T., Yokoi, T., & Lee, K. H. (1988). Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. II. Structural determination and total synthesis. The Journal of Antibiotics, 41(4), 488–493. https://doi.org/10.7164/antibiotics.41.488
Yang, L. M., R. Y. Wu, A. T. McPhail, T. Yokoi, and K. H. Lee. “Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. II. Structural determination and total synthesis.” The Journal of Antibiotics 41, no. 4 (April 1988): 488–93. https://doi.org/10.7164/antibiotics.41.488.
Yang LM, Wu RY, McPhail AT, Yokoi T, Lee KH. Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. II. Structural determination and total synthesis. The Journal of antibiotics. 1988 Apr;41(4):488–93.
Yang, L. M., et al. “Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. II. Structural determination and total synthesis.” The Journal of Antibiotics, vol. 41, no. 4, Apr. 1988, pp. 488–93. Epmc, doi:10.7164/antibiotics.41.488.
Yang LM, Wu RY, McPhail AT, Yokoi T, Lee KH. Neihumicin, a new cytotoxic antibiotic from Micromonospora neihuensis. II. Structural determination and total synthesis. The Journal of antibiotics. 1988 Apr;41(4):488–493.
Published In
The Journal of antibiotics
DOI
EISSN
1881-1469
ISSN
0021-8820
Publication Date
April 1988
Volume
41
Issue
4
Start / End Page
488 / 493
Related Subject Headings
- Pyrazines
- Microbiology
- Medicinal & Biomolecular Chemistry
- Chemistry
- Chemical Phenomena
- Antibiotics, Antineoplastic
- 3214 Pharmacology and pharmaceutical sciences
- 3107 Microbiology
- 1115 Pharmacology and Pharmaceutical Sciences
- 0605 Microbiology