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The role of protein phosphatases in synaptic transmission, plasticity and neuronal development.

Publication ,  Journal Article
Nairn, AC; Shenolikar, S
Published in: Curr Opin Neurobiol
June 1992

In the past year significant advances have been made in our understanding of the role of protein dephosphorylation in the control of neuronal function. Molecular cloning has identified a large number of serine/threonine and tyrosine protein phosphatases in the nervous system. Many of these enzymes are selectively enriched in the nervous system, some are localized to specific neurons, and yet others are expressed only during specific periods of neuronal development. The availability of purified protein phosphatases and selective inhibitors has facilitated the analysis of these enzymes and their role in the regulation of neurotransmitter receptors and ion channels.

Duke Scholars

Published In

Curr Opin Neurobiol

DOI

ISSN

0959-4388

Publication Date

June 1992

Volume

2

Issue

3

Start / End Page

296 / 301

Location

England

Related Subject Headings

  • Synaptic Transmission
  • Synapses
  • Phosphoprotein Phosphatases
  • Neurons
  • Neuronal Plasticity
  • Nervous System
  • Humans
  • Animals
  • 3209 Neurosciences
  • 1702 Cognitive Sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Nairn, A. C., & Shenolikar, S. (1992). The role of protein phosphatases in synaptic transmission, plasticity and neuronal development. Curr Opin Neurobiol, 2(3), 296–301. https://doi.org/10.1016/0959-4388(92)90118-5
Nairn, A. C., and S. Shenolikar. “The role of protein phosphatases in synaptic transmission, plasticity and neuronal development.Curr Opin Neurobiol 2, no. 3 (June 1992): 296–301. https://doi.org/10.1016/0959-4388(92)90118-5.
Nairn AC, Shenolikar S. The role of protein phosphatases in synaptic transmission, plasticity and neuronal development. Curr Opin Neurobiol. 1992 Jun;2(3):296–301.
Nairn, A. C., and S. Shenolikar. “The role of protein phosphatases in synaptic transmission, plasticity and neuronal development.Curr Opin Neurobiol, vol. 2, no. 3, June 1992, pp. 296–301. Pubmed, doi:10.1016/0959-4388(92)90118-5.
Nairn AC, Shenolikar S. The role of protein phosphatases in synaptic transmission, plasticity and neuronal development. Curr Opin Neurobiol. 1992 Jun;2(3):296–301.
Journal cover image

Published In

Curr Opin Neurobiol

DOI

ISSN

0959-4388

Publication Date

June 1992

Volume

2

Issue

3

Start / End Page

296 / 301

Location

England

Related Subject Headings

  • Synaptic Transmission
  • Synapses
  • Phosphoprotein Phosphatases
  • Neurons
  • Neuronal Plasticity
  • Nervous System
  • Humans
  • Animals
  • 3209 Neurosciences
  • 1702 Cognitive Sciences