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Treatment of hyperkalaemia using intravenous and nebulised salbutamol.

Publication ,  Journal Article
McClure, RJ; Prasad, VK; Brocklebank, JT
Published in: Arch Dis Child
February 1994

In 11 children (aged 5-18 years) with end stage chronic renal failure, the effect on plasma potassium of two doses of salbutamol (separated by two hours) given intravenously (4 micrograms/kg) and on a separate date, of salbutamol administered by nebuliser (2.5 mg if the child weighed below 25 kg, 5 mg if above) was observed. Within 30 minutes of the first dose, the mean plasma potassium concentration fell significantly by 0.87 and 0.61 mmol/l after intravenous and nebulised administration respectively. Sixty minutes after the second dose the plasma potassium was significantly reduced by a further 0.28 and 0.53 mmol/l respectively. There was a significant difference between the two methods of administration at 300 minutes after the first dose favouring nebulisation. No major side effects were observed. Nebulised salbutamol should be the first choice emergency treatment of hyperkalaemia.

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Published In

Arch Dis Child

DOI

EISSN

1468-2044

Publication Date

February 1994

Volume

70

Issue

2

Start / End Page

126 / 128

Location

England

Related Subject Headings

  • Potassium
  • Pediatrics
  • Nebulizers and Vaporizers
  • Kidney Failure, Chronic
  • Infusions, Intravenous
  • Hyperkalemia
  • Humans
  • Child, Preschool
  • Child
  • Albuterol
 

Citation

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McClure, R. J., Prasad, V. K., & Brocklebank, J. T. (1994). Treatment of hyperkalaemia using intravenous and nebulised salbutamol. Arch Dis Child, 70(2), 126–128. https://doi.org/10.1136/adc.70.2.126
McClure, R. J., V. K. Prasad, and J. T. Brocklebank. “Treatment of hyperkalaemia using intravenous and nebulised salbutamol.Arch Dis Child 70, no. 2 (February 1994): 126–28. https://doi.org/10.1136/adc.70.2.126.
McClure RJ, Prasad VK, Brocklebank JT. Treatment of hyperkalaemia using intravenous and nebulised salbutamol. Arch Dis Child. 1994 Feb;70(2):126–8.
McClure, R. J., et al. “Treatment of hyperkalaemia using intravenous and nebulised salbutamol.Arch Dis Child, vol. 70, no. 2, Feb. 1994, pp. 126–28. Pubmed, doi:10.1136/adc.70.2.126.
McClure RJ, Prasad VK, Brocklebank JT. Treatment of hyperkalaemia using intravenous and nebulised salbutamol. Arch Dis Child. 1994 Feb;70(2):126–128.

Published In

Arch Dis Child

DOI

EISSN

1468-2044

Publication Date

February 1994

Volume

70

Issue

2

Start / End Page

126 / 128

Location

England

Related Subject Headings

  • Potassium
  • Pediatrics
  • Nebulizers and Vaporizers
  • Kidney Failure, Chronic
  • Infusions, Intravenous
  • Hyperkalemia
  • Humans
  • Child, Preschool
  • Child
  • Albuterol