Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia.
Publication
, Journal Article
Andersson, U; Häggström, JE; Levin, ED; Bondesson, U; Valverius, M; Gunne, LM
Published in: Mov Disord
1989
Glutamate decarboxylase (GAD) activity was measured in the nuclei of the basal ganglia in patients with neuroleptic-induced tardive dyskinesia (TD) and controls matched for age and premortem state. In five TD patients, who all had a sudden death, a significant decrease in GAD activity was found in the subthalamic nucleus (STN). The lowered GAD activity in the STN may represent a biochemical substrate for neuroleptic-induced TD.
Duke Scholars
Published In
Mov Disord
DOI
ISSN
0885-3185
Publication Date
1989
Volume
4
Issue
1
Start / End Page
37 / 46
Location
United States
Related Subject Headings
- Thalamic Nuclei
- Neurology & Neurosurgery
- Myocardial Infarction
- Middle Aged
- Male
- Humans
- Glutamate Decarboxylase
- Female
- Dyskinesia, Drug-Induced
- Death, Sudden
Citation
APA
Chicago
ICMJE
MLA
NLM
Andersson, U., Häggström, J. E., Levin, E. D., Bondesson, U., Valverius, M., & Gunne, L. M. (1989). Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia. Mov Disord, 4(1), 37–46. https://doi.org/10.1002/mds.870040107
Andersson, U., J. E. Häggström, E. D. Levin, U. Bondesson, M. Valverius, and L. M. Gunne. “Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia.” Mov Disord 4, no. 1 (1989): 37–46. https://doi.org/10.1002/mds.870040107.
Andersson U, Häggström JE, Levin ED, Bondesson U, Valverius M, Gunne LM. Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia. Mov Disord. 1989;4(1):37–46.
Andersson, U., et al. “Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia.” Mov Disord, vol. 4, no. 1, 1989, pp. 37–46. Pubmed, doi:10.1002/mds.870040107.
Andersson U, Häggström JE, Levin ED, Bondesson U, Valverius M, Gunne LM. Reduced glutamate decarboxylase activity in the subthalamic nucleus in patients with tardive dyskinesia. Mov Disord. 1989;4(1):37–46.
Published In
Mov Disord
DOI
ISSN
0885-3185
Publication Date
1989
Volume
4
Issue
1
Start / End Page
37 / 46
Location
United States
Related Subject Headings
- Thalamic Nuclei
- Neurology & Neurosurgery
- Myocardial Infarction
- Middle Aged
- Male
- Humans
- Glutamate Decarboxylase
- Female
- Dyskinesia, Drug-Induced
- Death, Sudden