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Reconstruction with vascularized composite tissue in patients with excessive injury following surgery and irradiation.

Publication ,  Journal Article
Serafin, D; DeLand, M; Lesesne, CB; Smith, PJ; Noell, KT; Georgiade, N
Published in: Ann Plast Surg
January 1982

The biological effects of a single high dose of radiation are examined. Both cellular injury and repair are reviewed during early, intermediate, and late phases. Anticipated composite tissue morbidity is detailed for therapeutic radiation doses administered to the head and neck, breast and thorax, and perineum. Patients who demonstrated excessive time-dose fractionation values were irradiated with lower x-ray energies. Those in whom there was an overlap of treatment fields presented a serious challenge to the reconstructive surgeon. Judicious selection of well-vascularized composite tissue outside the portals of irradiation, preferably with a long vascular pedicle, facilitated reconstruction. When possible, both donor and recipient vasculature should be outside the irradiated area to ensure uninterrupted blood flow to the transferred or transplanted tissue.

Duke Scholars

Published In

Ann Plast Surg

DOI

ISSN

0148-7043

Publication Date

January 1982

Volume

8

Issue

1

Start / End Page

35 / 54

Location

United States

Related Subject Headings

  • Urogenital Neoplasms
  • Surgical Flaps
  • Surgery
  • Radiation Injuries
  • Perineum
  • Neoplasms
  • Middle Aged
  • Humans
  • Head and Neck Neoplasms
  • Gastrointestinal Neoplasms
 

Citation

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Serafin, D., DeLand, M., Lesesne, C. B., Smith, P. J., Noell, K. T., & Georgiade, N. (1982). Reconstruction with vascularized composite tissue in patients with excessive injury following surgery and irradiation. Ann Plast Surg, 8(1), 35–54. https://doi.org/10.1097/00000637-198201000-00008
Serafin, D., M. DeLand, C. B. Lesesne, P. J. Smith, K. T. Noell, and N. Georgiade. “Reconstruction with vascularized composite tissue in patients with excessive injury following surgery and irradiation.Ann Plast Surg 8, no. 1 (January 1982): 35–54. https://doi.org/10.1097/00000637-198201000-00008.
Serafin D, DeLand M, Lesesne CB, Smith PJ, Noell KT, Georgiade N. Reconstruction with vascularized composite tissue in patients with excessive injury following surgery and irradiation. Ann Plast Surg. 1982 Jan;8(1):35–54.
Serafin, D., et al. “Reconstruction with vascularized composite tissue in patients with excessive injury following surgery and irradiation.Ann Plast Surg, vol. 8, no. 1, Jan. 1982, pp. 35–54. Pubmed, doi:10.1097/00000637-198201000-00008.
Serafin D, DeLand M, Lesesne CB, Smith PJ, Noell KT, Georgiade N. Reconstruction with vascularized composite tissue in patients with excessive injury following surgery and irradiation. Ann Plast Surg. 1982 Jan;8(1):35–54.

Published In

Ann Plast Surg

DOI

ISSN

0148-7043

Publication Date

January 1982

Volume

8

Issue

1

Start / End Page

35 / 54

Location

United States

Related Subject Headings

  • Urogenital Neoplasms
  • Surgical Flaps
  • Surgery
  • Radiation Injuries
  • Perineum
  • Neoplasms
  • Middle Aged
  • Humans
  • Head and Neck Neoplasms
  • Gastrointestinal Neoplasms