Platinum-catalyzed intramolecular hydroamination of unactivated olefins with secondary alkylamines.
Publication
, Journal Article
Bender, CF; Widenhoefer, RA
Published in: Journal of the American Chemical Society
February 2005
Reaction of benzyl-2,2-diphenyl-4-pentenylamine with a catalytic 1:2 mixture of [PtCl2(H2C=CH2)]2 (2.5 mol %) and PPh3 in dioxane at 120 degrees C for 16 h led to isolation of 1-benzyl-2-methyl-4,4-diphenylpyrrolidine in 75% yield. A number of gamma- and delta-amino olefins underwent intramolecular hydroamination to form the corresponding pyrrolidine derivatives in moderate to good yield. The reaction displayed excellent functional group compatibility and low moisture sensitivity.
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Published In
Journal of the American Chemical Society
DOI
EISSN
1520-5126
ISSN
0002-7863
Publication Date
February 2005
Volume
127
Issue
4
Start / End Page
1070 / 1071
Related Subject Headings
- Organoplatinum Compounds
- General Chemistry
- Catalysis
- Amines
- Amination
- Alkenes
- 40 Engineering
- 34 Chemical sciences
- 03 Chemical Sciences
Citation
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ICMJE
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Bender, C. F., & Widenhoefer, R. A. (2005). Platinum-catalyzed intramolecular hydroamination of unactivated olefins with secondary alkylamines. Journal of the American Chemical Society, 127(4), 1070–1071. https://doi.org/10.1021/ja043278q
Bender, Christopher F., and Ross A. Widenhoefer. “Platinum-catalyzed intramolecular hydroamination of unactivated olefins with secondary alkylamines.” Journal of the American Chemical Society 127, no. 4 (February 2005): 1070–71. https://doi.org/10.1021/ja043278q.
Bender CF, Widenhoefer RA. Platinum-catalyzed intramolecular hydroamination of unactivated olefins with secondary alkylamines. Journal of the American Chemical Society. 2005 Feb;127(4):1070–1.
Bender, Christopher F., and Ross A. Widenhoefer. “Platinum-catalyzed intramolecular hydroamination of unactivated olefins with secondary alkylamines.” Journal of the American Chemical Society, vol. 127, no. 4, Feb. 2005, pp. 1070–71. Epmc, doi:10.1021/ja043278q.
Bender CF, Widenhoefer RA. Platinum-catalyzed intramolecular hydroamination of unactivated olefins with secondary alkylamines. Journal of the American Chemical Society. 2005 Feb;127(4):1070–1071.
Published In
Journal of the American Chemical Society
DOI
EISSN
1520-5126
ISSN
0002-7863
Publication Date
February 2005
Volume
127
Issue
4
Start / End Page
1070 / 1071
Related Subject Headings
- Organoplatinum Compounds
- General Chemistry
- Catalysis
- Amines
- Amination
- Alkenes
- 40 Engineering
- 34 Chemical sciences
- 03 Chemical Sciences