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Cimetidine for stress-ulcer prophylaxis.

Publication ,  Journal Article
Greene, WL; Bollinger, RR
Published in: Crit Care Med
July 1984

Although cimetidine is more effective than a placebo for the prophylaxis of stress-induced ulcers, it has no advantage over titrated antacid dosing. Several comparative studies even suggest that combining cimetidine with antacid is no more effective than use of full-dose antacid. Therefore, we recommend prophylactic use of cimetidine only when very large dosages of antacid are required, in order to minimize acid-base disturbances.

Duke Scholars

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Published In

Crit Care Med

DOI

ISSN

0090-3493

Publication Date

July 1984

Volume

12

Issue

7

Start / End Page

571 / 575

Location

United States

Related Subject Headings

  • Stress, Physiological
  • Random Allocation
  • Peptic Ulcer
  • Humans
  • Gastric Mucosa
  • Gastric Juice
  • Emergency & Critical Care Medicine
  • Clinical Trials as Topic
  • Cimetidine
  • Antacids
 

Citation

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Greene, W. L., & Bollinger, R. R. (1984). Cimetidine for stress-ulcer prophylaxis. Crit Care Med, 12(7), 571–575. https://doi.org/10.1097/00003246-198407000-00005
Greene, W. L., and R. R. Bollinger. “Cimetidine for stress-ulcer prophylaxis.Crit Care Med 12, no. 7 (July 1984): 571–75. https://doi.org/10.1097/00003246-198407000-00005.
Greene WL, Bollinger RR. Cimetidine for stress-ulcer prophylaxis. Crit Care Med. 1984 Jul;12(7):571–5.
Greene, W. L., and R. R. Bollinger. “Cimetidine for stress-ulcer prophylaxis.Crit Care Med, vol. 12, no. 7, July 1984, pp. 571–75. Pubmed, doi:10.1097/00003246-198407000-00005.
Greene WL, Bollinger RR. Cimetidine for stress-ulcer prophylaxis. Crit Care Med. 1984 Jul;12(7):571–575.

Published In

Crit Care Med

DOI

ISSN

0090-3493

Publication Date

July 1984

Volume

12

Issue

7

Start / End Page

571 / 575

Location

United States

Related Subject Headings

  • Stress, Physiological
  • Random Allocation
  • Peptic Ulcer
  • Humans
  • Gastric Mucosa
  • Gastric Juice
  • Emergency & Critical Care Medicine
  • Clinical Trials as Topic
  • Cimetidine
  • Antacids