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AIDS-associated Kaposi's sarcoma: variables associated with survival.

Publication ,  Journal Article
Myskowski, PL; Niedzwiecki, D; Shurgot, BA; Kaufman, D; Krown, SE; Nisce, L; Safai, B
Published in: J Am Acad Dermatol
June 1988

The records of 187 consecutive patients with acquired immunodeficiency syndrome (AIDS)-associated Kaposi's sarcoma were analyzed retrospectively for a number of prognostic variables. In a multivariate analysis, the initial site of disease was found to be related to survival. Initial lesions on the skin of the lower extremities or in the lymph nodes were associated with longer survival (p = 0.005 and p = 0.01, respectively). Higher helper/suppressor T cell ratios were strongly associated with longer survival (p less than 0.0001). Age and serum IgG antibody levels to cytomegalovirus did not appear to correlate. These results suggest that there are different subgroups of patients with AIDS-associated Kaposi's sarcoma, and that the initial site of disease, as well as immunologic parameters, may be useful in prognosis.

Duke Scholars

Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

June 1988

Volume

18

Issue

6

Start / End Page

1299 / 1306

Location

United States

Related Subject Headings

  • T-Lymphocytes, Regulatory
  • T-Lymphocytes, Helper-Inducer
  • T-Lymphocytes
  • Skin Neoplasms
  • Sarcoma, Kaposi
  • Retrospective Studies
  • Prognosis
  • Middle Aged
  • Male
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Myskowski, P. L., Niedzwiecki, D., Shurgot, B. A., Kaufman, D., Krown, S. E., Nisce, L., & Safai, B. (1988). AIDS-associated Kaposi's sarcoma: variables associated with survival. J Am Acad Dermatol, 18(6), 1299–1306. https://doi.org/10.1016/s0190-9622(88)70138-3
Myskowski, P. L., D. Niedzwiecki, B. A. Shurgot, D. Kaufman, S. E. Krown, L. Nisce, and B. Safai. “AIDS-associated Kaposi's sarcoma: variables associated with survival.J Am Acad Dermatol 18, no. 6 (June 1988): 1299–1306. https://doi.org/10.1016/s0190-9622(88)70138-3.
Myskowski PL, Niedzwiecki D, Shurgot BA, Kaufman D, Krown SE, Nisce L, et al. AIDS-associated Kaposi's sarcoma: variables associated with survival. J Am Acad Dermatol. 1988 Jun;18(6):1299–306.
Myskowski, P. L., et al. “AIDS-associated Kaposi's sarcoma: variables associated with survival.J Am Acad Dermatol, vol. 18, no. 6, June 1988, pp. 1299–306. Pubmed, doi:10.1016/s0190-9622(88)70138-3.
Myskowski PL, Niedzwiecki D, Shurgot BA, Kaufman D, Krown SE, Nisce L, Safai B. AIDS-associated Kaposi's sarcoma: variables associated with survival. J Am Acad Dermatol. 1988 Jun;18(6):1299–1306.
Journal cover image

Published In

J Am Acad Dermatol

DOI

ISSN

0190-9622

Publication Date

June 1988

Volume

18

Issue

6

Start / End Page

1299 / 1306

Location

United States

Related Subject Headings

  • T-Lymphocytes, Regulatory
  • T-Lymphocytes, Helper-Inducer
  • T-Lymphocytes
  • Skin Neoplasms
  • Sarcoma, Kaposi
  • Retrospective Studies
  • Prognosis
  • Middle Aged
  • Male
  • Humans