Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.
Publication
, Journal Article
Kypson, AP; Morphew, E; Jones, R; Gottfried, MR; Seigler, HF
Published in: J Surg Oncol
February 2003
The rare finding of heterotopic ossification in a case of primary rectal adenocarcinoma is described along with a review of the literature. Immunohistochemistry for a bone morphogenic protein (BMP-2) and fibroblast growth factor (FGF-2), both of which induce and stimulate bone formation, was performed and revealed overexpression of BMP-2 by the tumor cells, elucidating a possible mechanism which up to now had been based merely on speculation.
Duke Scholars
Published In
J Surg Oncol
DOI
ISSN
0022-4790
Publication Date
February 2003
Volume
82
Issue
2
Start / End Page
132 / 136
Location
United States
Related Subject Headings
- Uracil
- Treatment Outcome
- Transforming Growth Factor beta
- Rectal Neoplasms
- Radiotherapy, Adjuvant
- Ossification, Heterotopic
- Oncology & Carcinogenesis
- Neoadjuvant Therapy
- Immunohistochemistry
- Humans
Citation
APA
Chicago
ICMJE
MLA
NLM
Kypson, A. P., Morphew, E., Jones, R., Gottfried, M. R., & Seigler, H. F. (2003). Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism. J Surg Oncol, 82(2), 132–136. https://doi.org/10.1002/jso.10181
Kypson, Alan P., Emilie Morphew, Relief Jones, Marcia R. Gottfried, and Hilliard F. Seigler. “Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.” J Surg Oncol 82, no. 2 (February 2003): 132–36. https://doi.org/10.1002/jso.10181.
Kypson AP, Morphew E, Jones R, Gottfried MR, Seigler HF. Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism. J Surg Oncol. 2003 Feb;82(2):132–6.
Kypson, Alan P., et al. “Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism.” J Surg Oncol, vol. 82, no. 2, Feb. 2003, pp. 132–36. Pubmed, doi:10.1002/jso.10181.
Kypson AP, Morphew E, Jones R, Gottfried MR, Seigler HF. Heterotopic ossification in rectal cancer: Rare finding with a novel proposed mechanism. J Surg Oncol. 2003 Feb;82(2):132–136.
Published In
J Surg Oncol
DOI
ISSN
0022-4790
Publication Date
February 2003
Volume
82
Issue
2
Start / End Page
132 / 136
Location
United States
Related Subject Headings
- Uracil
- Treatment Outcome
- Transforming Growth Factor beta
- Rectal Neoplasms
- Radiotherapy, Adjuvant
- Ossification, Heterotopic
- Oncology & Carcinogenesis
- Neoadjuvant Therapy
- Immunohistochemistry
- Humans