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Childhood hepatic mesenchymoma: successful treatment with surgery and multiple-agent chemotherapy.

Publication ,  Journal Article
Ware, R; Friedman, HS; Filston, HC; Chaffee, S; Kurtzberg, J; Kinney, TR; Falletta, JM
Published in: Med Pediatr Oncol
1988

Malignant undifferentiated sarcoma (mesenchymoma) of the liver is a rare tumor of childhood, with fewer than 100 cases reported in the literature. The overall prognosis for patients with this malignancy is poor. In this report, two children with hepatic mesenchymoma underwent surgical excision followed by 2 years of adjuvant chemotherapy. Rotating cycles of cisplatinum, vincristine/doxorubicin, vincristine/cyclophosphamide, and vincristine/actinomycin D were given with minimal toxicity. Both patients are alive, with no evidence of disease at least 5 years from diagnosis. Previous reports of treatment are reviewed.

Duke Scholars

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1988

Volume

16

Issue

1

Start / End Page

62 / 65

Location

United States

Related Subject Headings

  • Vincristine
  • Oncology & Carcinogenesis
  • Mesenchymoma
  • Male
  • Liver Neoplasms
  • Humans
  • Female
  • Doxorubicin
  • Cyclophosphamide
  • Combined Modality Therapy
 

Citation

APA
Chicago
ICMJE
MLA
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Ware, R., Friedman, H. S., Filston, H. C., Chaffee, S., Kurtzberg, J., Kinney, T. R., & Falletta, J. M. (1988). Childhood hepatic mesenchymoma: successful treatment with surgery and multiple-agent chemotherapy. Med Pediatr Oncol, 16(1), 62–65. https://doi.org/10.1002/mpo.2950160114
Ware, R., H. S. Friedman, H. C. Filston, S. Chaffee, J. Kurtzberg, T. R. Kinney, and J. M. Falletta. “Childhood hepatic mesenchymoma: successful treatment with surgery and multiple-agent chemotherapy.Med Pediatr Oncol 16, no. 1 (1988): 62–65. https://doi.org/10.1002/mpo.2950160114.
Ware R, Friedman HS, Filston HC, Chaffee S, Kurtzberg J, Kinney TR, et al. Childhood hepatic mesenchymoma: successful treatment with surgery and multiple-agent chemotherapy. Med Pediatr Oncol. 1988;16(1):62–5.
Ware, R., et al. “Childhood hepatic mesenchymoma: successful treatment with surgery and multiple-agent chemotherapy.Med Pediatr Oncol, vol. 16, no. 1, 1988, pp. 62–65. Pubmed, doi:10.1002/mpo.2950160114.
Ware R, Friedman HS, Filston HC, Chaffee S, Kurtzberg J, Kinney TR, Falletta JM. Childhood hepatic mesenchymoma: successful treatment with surgery and multiple-agent chemotherapy. Med Pediatr Oncol. 1988;16(1):62–65.

Published In

Med Pediatr Oncol

DOI

ISSN

0098-1532

Publication Date

1988

Volume

16

Issue

1

Start / End Page

62 / 65

Location

United States

Related Subject Headings

  • Vincristine
  • Oncology & Carcinogenesis
  • Mesenchymoma
  • Male
  • Liver Neoplasms
  • Humans
  • Female
  • Doxorubicin
  • Cyclophosphamide
  • Combined Modality Therapy