Treatment of trilateral retinoblastoma with vincristine and cyclophosphamide.
Publication
, Journal Article
Malik, RK; Friedman, HS; Djang, WT; Falletta, JM; Buckley, E; Kurtzberg, J; Kinney, TR; Stine, K; Chaffee, S; Hayes, J
Published in: Am J Ophthalmol
November 15, 1986
Current therapy for patients with trilateral retinoblastoma, consisting primarily of surgical intervention and radiotherapy, has resulted in no long-term survivors. The use of adjuvant chemotherapy has not improved this outcome. After observing a tumor response to cyclophosphamide in a patient with suprasellar retinoblastoma, we treated a subsequent patient with trilateral retinoblastoma with both vincristine and cyclophosphamide. Objective tumor regression resulted. Although the tumor ultimately progressed in both patients, these findings suggest that vincristine and cyclophosphamide are active in patients with intracranial (trilateral) retinoblastoma.
Duke Scholars
Published In
Am J Ophthalmol
DOI
ISSN
0002-9394
Publication Date
November 15, 1986
Volume
102
Issue
5
Start / End Page
650 / 656
Location
United States
Related Subject Headings
- Vincristine
- Tomography, X-Ray Computed
- Retinoblastoma
- Ophthalmology & Optometry
- Infant
- Humans
- Female
- Eye Neoplasms
- Cyclophosphamide
- 3212 Ophthalmology and optometry
Citation
APA
Chicago
ICMJE
MLA
NLM
Malik, R. K., Friedman, H. S., Djang, W. T., Falletta, J. M., Buckley, E., Kurtzberg, J., … Hayes, J. (1986). Treatment of trilateral retinoblastoma with vincristine and cyclophosphamide. Am J Ophthalmol, 102(5), 650–656. https://doi.org/10.1016/0002-9394(86)90540-4
Malik, R. K., H. S. Friedman, W. T. Djang, J. M. Falletta, E. Buckley, J. Kurtzberg, T. R. Kinney, K. Stine, S. Chaffee, and J. Hayes. “Treatment of trilateral retinoblastoma with vincristine and cyclophosphamide.” Am J Ophthalmol 102, no. 5 (November 15, 1986): 650–56. https://doi.org/10.1016/0002-9394(86)90540-4.
Malik RK, Friedman HS, Djang WT, Falletta JM, Buckley E, Kurtzberg J, et al. Treatment of trilateral retinoblastoma with vincristine and cyclophosphamide. Am J Ophthalmol. 1986 Nov 15;102(5):650–6.
Malik, R. K., et al. “Treatment of trilateral retinoblastoma with vincristine and cyclophosphamide.” Am J Ophthalmol, vol. 102, no. 5, Nov. 1986, pp. 650–56. Pubmed, doi:10.1016/0002-9394(86)90540-4.
Malik RK, Friedman HS, Djang WT, Falletta JM, Buckley E, Kurtzberg J, Kinney TR, Stine K, Chaffee S, Hayes J. Treatment of trilateral retinoblastoma with vincristine and cyclophosphamide. Am J Ophthalmol. 1986 Nov 15;102(5):650–656.
Published In
Am J Ophthalmol
DOI
ISSN
0002-9394
Publication Date
November 15, 1986
Volume
102
Issue
5
Start / End Page
650 / 656
Location
United States
Related Subject Headings
- Vincristine
- Tomography, X-Ray Computed
- Retinoblastoma
- Ophthalmology & Optometry
- Infant
- Humans
- Female
- Eye Neoplasms
- Cyclophosphamide
- 3212 Ophthalmology and optometry