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The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia.

Publication ,  Journal Article
Garrett, KD; Browndyke, JN; Whelihan, W; Paul, RH; DiCarlo, M; Moser, DJ; Cohen, RA; Ott, BR
Published in: Arch Clin Neuropsychol
September 2004

Hachinski and co-workers have used the term vascular cognitive impairment-no dementia (VaCIND) to represent the earliest stages of cognitive decline associated with vascular changes [Neurology 57 (4) (2001) 714]. However, the neuropsychological profile of vascular CIND remains unclear. Twenty-five healthy elders, 29 individuals at risk for cerebrovascular disease (R-CVD), 18 individuals with VaCIND, and 26 individuals with vascular dementia (VaD) were examined to determine whether patterns of neuropsychological assessment performance can assist in the differentiation of patients at varying levels of risk and severity for cerebrovascular disease and VaD. The R-CVD group performed within normal expectations on most cognitive measures as compared to the elderly control sample and published clinical norms. Relative to elderly controls, the VaCIND group demonstrated significant difficulties on measures of cognitive flexibility, verbal retrieval, and verbal recognition memory, but not on measures of confrontational naming or verbal fluency. The VaD group was impaired on all cognitive measures assessed. The current findings suggest that poor cognitive flexibility and verbal retrieval in the context of preserved function in other domains may characterize the prodromal stage of VaD.

Duke Scholars

Published In

Arch Clin Neuropsychol

DOI

ISSN

0887-6177

Publication Date

September 2004

Volume

19

Issue

6

Start / End Page

745 / 757

Location

United States

Related Subject Headings

  • Reproducibility of Results
  • Reference Values
  • Psychometrics
  • Neuropsychological Tests
  • Middle Aged
  • Mental Status Schedule
  • Male
  • Humans
  • Health Status Indicators
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Garrett, K. D., Browndyke, J. N., Whelihan, W., Paul, R. H., DiCarlo, M., Moser, D. J., … Ott, B. R. (2004). The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia. Arch Clin Neuropsychol, 19(6), 745–757. https://doi.org/10.1016/j.acn.2003.09.008
Garrett, Kelly Davis, Jeffrey N. Browndyke, William Whelihan, Robert H. Paul, Margaret DiCarlo, David J. Moser, Ronald A. Cohen, and Brian R. Ott. “The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia.Arch Clin Neuropsychol 19, no. 6 (September 2004): 745–57. https://doi.org/10.1016/j.acn.2003.09.008.
Garrett KD, Browndyke JN, Whelihan W, Paul RH, DiCarlo M, Moser DJ, et al. The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia. Arch Clin Neuropsychol. 2004 Sep;19(6):745–57.
Garrett, Kelly Davis, et al. “The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia.Arch Clin Neuropsychol, vol. 19, no. 6, Sept. 2004, pp. 745–57. Pubmed, doi:10.1016/j.acn.2003.09.008.
Garrett KD, Browndyke JN, Whelihan W, Paul RH, DiCarlo M, Moser DJ, Cohen RA, Ott BR. The neuropsychological profile of vascular cognitive impairment--no dementia: comparisons to patients at risk for cerebrovascular disease and vascular dementia. Arch Clin Neuropsychol. 2004 Sep;19(6):745–757.
Journal cover image

Published In

Arch Clin Neuropsychol

DOI

ISSN

0887-6177

Publication Date

September 2004

Volume

19

Issue

6

Start / End Page

745 / 757

Location

United States

Related Subject Headings

  • Reproducibility of Results
  • Reference Values
  • Psychometrics
  • Neuropsychological Tests
  • Middle Aged
  • Mental Status Schedule
  • Male
  • Humans
  • Health Status Indicators
  • Female