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Getting at the root and stem of brain tumors.

Publication ,  Journal Article
Oliver, TG; Wechsler-Reya, RJ
Published in: Neuron
June 24, 2004

Brain tumors are among the most aggressive and intractable types of cancer. Recent studies indicate that brain tumor cells resemble neural stem cells in terms of phenotype, signaling, and behavior in vitro. In light of these similarities, it has been suggested that brain tumors arise from stem cells, that they co-opt stem cell strategies for self-renewal, and even that they contain "cancer stem cells" that are critical for tumor maintenance. We will examine these possibilities and discuss their implications for the understanding and treatment of brain tumors.

Duke Scholars

Published In

Neuron

DOI

ISSN

0896-6273

Publication Date

June 24, 2004

Volume

42

Issue

6

Start / End Page

885 / 888

Location

United States

Related Subject Headings

  • Stem Cells
  • Neurons
  • Neurology & Neurosurgery
  • Humans
  • Cell Transformation, Neoplastic
  • Cell Differentiation
  • Brain Neoplasms
  • Biomarkers
  • Animals
  • 5202 Biological psychology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Oliver, T. G., & Wechsler-Reya, R. J. (2004). Getting at the root and stem of brain tumors. Neuron, 42(6), 885–888. https://doi.org/10.1016/j.neuron.2004.06.011
Oliver, Trudy G., and Robert J. Wechsler-Reya. “Getting at the root and stem of brain tumors.Neuron 42, no. 6 (June 24, 2004): 885–88. https://doi.org/10.1016/j.neuron.2004.06.011.
Oliver TG, Wechsler-Reya RJ. Getting at the root and stem of brain tumors. Neuron. 2004 Jun 24;42(6):885–8.
Oliver, Trudy G., and Robert J. Wechsler-Reya. “Getting at the root and stem of brain tumors.Neuron, vol. 42, no. 6, June 2004, pp. 885–88. Pubmed, doi:10.1016/j.neuron.2004.06.011.
Oliver TG, Wechsler-Reya RJ. Getting at the root and stem of brain tumors. Neuron. 2004 Jun 24;42(6):885–888.
Journal cover image

Published In

Neuron

DOI

ISSN

0896-6273

Publication Date

June 24, 2004

Volume

42

Issue

6

Start / End Page

885 / 888

Location

United States

Related Subject Headings

  • Stem Cells
  • Neurons
  • Neurology & Neurosurgery
  • Humans
  • Cell Transformation, Neoplastic
  • Cell Differentiation
  • Brain Neoplasms
  • Biomarkers
  • Animals
  • 5202 Biological psychology