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The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.

Publication ,  Journal Article
Provenzale, JM; Mukundan, S; Dewhirst, M
Published in: AJR Am J Roentgenol
September 2005

OBJECTIVE: Our purpose is to describe methods of assessing leakiness of the blood-brain barrier and explain mechanisms for exploiting the blood-brain barrier for therapeutic purposes. CONCLUSION: Knowledge of the workings of the blood-brain barrier is important for an understanding of the ways in which blood-brain barrier permeability may be used as a surrogate marker for drug therapeutic response. Manipulation of the blood-brain barrier may provide a means for selectively targeting tumors for drug delivery.

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Published In

AJR Am J Roentgenol

DOI

ISSN

0361-803X

Publication Date

September 2005

Volume

185

Issue

3

Start / End Page

763 / 767

Location

United States

Related Subject Headings

  • Permeability
  • Nuclear Medicine & Medical Imaging
  • Neovascularization, Pathologic
  • Magnetic Resonance Imaging
  • Humans
  • Contrast Media
  • Brain Neoplasms
  • Blood-Brain Barrier
  • Biological Transport
  • Animals
 

Citation

APA
Chicago
ICMJE
MLA
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Provenzale, J. M., Mukundan, S., & Dewhirst, M. (2005). The role of blood-brain barrier permeability in brain tumor imaging and therapeutics. AJR Am J Roentgenol, 185(3), 763–767. https://doi.org/10.2214/ajr.185.3.01850763
Provenzale, James M., Srinivasan Mukundan, and Mark Dewhirst. “The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.AJR Am J Roentgenol 185, no. 3 (September 2005): 763–67. https://doi.org/10.2214/ajr.185.3.01850763.
Provenzale JM, Mukundan S, Dewhirst M. The role of blood-brain barrier permeability in brain tumor imaging and therapeutics. AJR Am J Roentgenol. 2005 Sep;185(3):763–7.
Provenzale, James M., et al. “The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.AJR Am J Roentgenol, vol. 185, no. 3, Sept. 2005, pp. 763–67. Pubmed, doi:10.2214/ajr.185.3.01850763.
Provenzale JM, Mukundan S, Dewhirst M. The role of blood-brain barrier permeability in brain tumor imaging and therapeutics. AJR Am J Roentgenol. 2005 Sep;185(3):763–767.

Published In

AJR Am J Roentgenol

DOI

ISSN

0361-803X

Publication Date

September 2005

Volume

185

Issue

3

Start / End Page

763 / 767

Location

United States

Related Subject Headings

  • Permeability
  • Nuclear Medicine & Medical Imaging
  • Neovascularization, Pathologic
  • Magnetic Resonance Imaging
  • Humans
  • Contrast Media
  • Brain Neoplasms
  • Blood-Brain Barrier
  • Biological Transport
  • Animals