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Calmodulin and the cell cycle: involvement in regulation of cell-cycle progression.

Publication ,  Journal Article
Chafouleas, JG; Bolton, WE; Hidaka, H; Boyd, AE; Means, AR
Published in: Cell
January 1982

Calmodulin levels are elevated twofold at late G1 and/or early S phases during the growth cycle of CHO-K1 cells. These levels are maintained throughout the remainder of the cell cycle unit cytokinesis. The G1 daughter cells then contain half the intracellular calmodulin level found prior to cell division. Elevation of calmodulin at the G1-S boundary is independent of the length of G1, and the increase in calmodulin appears to be related to progression into S phase. The importance of calmodulin for G1-S progression is suggested by the ability of the anticalmodulin drug W13 to elicit specific and reversible progression delays into and through S phase.

Duke Scholars

Published In

Cell

DOI

ISSN

0092-8674

Publication Date

January 1982

Volume

28

Issue

1

Start / End Page

41 / 50

Location

United States

Related Subject Headings

  • Sulfonamides
  • Ovary
  • Female
  • Developmental Biology
  • DNA Replication
  • Cricetulus
  • Cricetinae
  • Cell Line
  • Cell Cycle
  • Calmodulin
 

Citation

APA
Chicago
ICMJE
MLA
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Chafouleas, J. G., Bolton, W. E., Hidaka, H., Boyd, A. E., & Means, A. R. (1982). Calmodulin and the cell cycle: involvement in regulation of cell-cycle progression. Cell, 28(1), 41–50. https://doi.org/10.1016/0092-8674(82)90373-7
Chafouleas, J. G., W. E. Bolton, H. Hidaka, A. E. Boyd, and A. R. Means. “Calmodulin and the cell cycle: involvement in regulation of cell-cycle progression.Cell 28, no. 1 (January 1982): 41–50. https://doi.org/10.1016/0092-8674(82)90373-7.
Chafouleas JG, Bolton WE, Hidaka H, Boyd AE, Means AR. Calmodulin and the cell cycle: involvement in regulation of cell-cycle progression. Cell. 1982 Jan;28(1):41–50.
Chafouleas, J. G., et al. “Calmodulin and the cell cycle: involvement in regulation of cell-cycle progression.Cell, vol. 28, no. 1, Jan. 1982, pp. 41–50. Pubmed, doi:10.1016/0092-8674(82)90373-7.
Chafouleas JG, Bolton WE, Hidaka H, Boyd AE, Means AR. Calmodulin and the cell cycle: involvement in regulation of cell-cycle progression. Cell. 1982 Jan;28(1):41–50.
Journal cover image

Published In

Cell

DOI

ISSN

0092-8674

Publication Date

January 1982

Volume

28

Issue

1

Start / End Page

41 / 50

Location

United States

Related Subject Headings

  • Sulfonamides
  • Ovary
  • Female
  • Developmental Biology
  • DNA Replication
  • Cricetulus
  • Cricetinae
  • Cell Line
  • Cell Cycle
  • Calmodulin