Three-dimensional structure of calmodulin.
Publication
, Journal Article
Babu, YS; Sack, JS; Greenhough, TJ; Bugg, CE; Means, AR; Cook, WJ
Published in: Nature
May 2, 1985
The three-dimensional structure of calmodulin has been determined crystallographically at 3.0 A resolution. The molecule consists of two globular lobes connected by a long exposed alpha-helix. Each lobe binds two calcium ions through helix-loop-helix domains similar to those of other calcium-binding proteins. The long helix between the lobes may be involved in interactions of calmodulin with drugs and various proteins.
Duke Scholars
Published In
Nature
DOI
ISSN
0028-0836
Publication Date
May 2, 1985
Volume
315
Issue
6014
Start / End Page
37 / 40
Location
England
Related Subject Headings
- Troponin C
- Troponin
- Structure-Activity Relationship
- Rats
- Protein Conformation
- Models, Molecular
- Male
- General Science & Technology
- Calmodulin
- Calcium
Citation
APA
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ICMJE
MLA
NLM
Babu, Y. S., Sack, J. S., Greenhough, T. J., Bugg, C. E., Means, A. R., & Cook, W. J. (1985). Three-dimensional structure of calmodulin. Nature, 315(6014), 37–40. https://doi.org/10.1038/315037a0
Babu, Y. S., J. S. Sack, T. J. Greenhough, C. E. Bugg, A. R. Means, and W. J. Cook. “Three-dimensional structure of calmodulin.” Nature 315, no. 6014 (May 2, 1985): 37–40. https://doi.org/10.1038/315037a0.
Babu YS, Sack JS, Greenhough TJ, Bugg CE, Means AR, Cook WJ. Three-dimensional structure of calmodulin. Nature. 1985 May 2;315(6014):37–40.
Babu, Y. S., et al. “Three-dimensional structure of calmodulin.” Nature, vol. 315, no. 6014, May 1985, pp. 37–40. Pubmed, doi:10.1038/315037a0.
Babu YS, Sack JS, Greenhough TJ, Bugg CE, Means AR, Cook WJ. Three-dimensional structure of calmodulin. Nature. 1985 May 2;315(6014):37–40.
Published In
Nature
DOI
ISSN
0028-0836
Publication Date
May 2, 1985
Volume
315
Issue
6014
Start / End Page
37 / 40
Location
England
Related Subject Headings
- Troponin C
- Troponin
- Structure-Activity Relationship
- Rats
- Protein Conformation
- Models, Molecular
- Male
- General Science & Technology
- Calmodulin
- Calcium