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Innovations in shock wave lithotripsy technology: updates in experimental studies.

Publication ,  Journal Article
Zhou, Y; Cocks, FH; Preminger, GM; Zhong, P
Published in: J Urol
November 2004

PURPOSE: We developed innovations in shock wave lithotripsy (SWL) technology. MATERIALS AND METHODS: Two technical upgrades were implemented in an original unmodified HM-3 lithotriptor (Dornier Medical Systems, Inc., Kennesaw, Georgia). First, a single unit ellipsoidal reflector insert was used to modify the profile of lithotriptor shock wave (LSW) to decrease the propensity of tissue injury in SWL. Second, a piezoelectric annular array (PEAA) generator (f = 230 kHz and F = 150 mm) was used to produce an auxiliary shock wave of approximately 13 MPa in peak pressure (at 4 kV output voltage) to intensify the collapse of LSW induced bubbles near the target stone for improved comminution efficiency. RESULTS: Consistent rupture of a vessel phantom made of single cellulose hollow fiber (i.d. = 0.2 mm) was produced after 30 shocks by the original HM-3 reflector at 20 kV. In comparison no vessel rupture could be produced after 200 shocks using the upgraded reflector at 22 kV or the PEAA generator at 4 kV. Using cylindrical BegoStone phantoms (Bego USA, Smithfield, Rhode Island) stone comminution efficiencies (mean +/- sd) after 1,500 shocks produced by the original and upgraded HM-3 reflectors, and the combined PEAA/upgraded HM-3 system, were 81.3% +/- 3.5%, 90.1% +/- 4.3% and 95.2% +/- 3.3%, respectively (p<0.05). CONCLUSIONS: Optimization of the pulse profile and sequence of LSW can significantly improve stone comminution while simultaneously decreasing the propensity of tissue injury during in vitro SWL. This novel concept and associated technologies may be used to upgrade other existing lithotriptors and to design new shock wave lithotriptors for improved performance and safety.

Duke Scholars

Published In

J Urol

DOI

ISSN

0022-5347

Publication Date

November 2004

Volume

172

Issue

5 Pt 1

Start / End Page

1892 / 1898

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Lithotripsy
  • Equipment Design
  • 3202 Clinical sciences
  • 1103 Clinical Sciences
 

Citation

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ICMJE
MLA
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Zhou, Y., Cocks, F. H., Preminger, G. M., & Zhong, P. (2004). Innovations in shock wave lithotripsy technology: updates in experimental studies. J Urol, 172(5 Pt 1), 1892–1898. https://doi.org/10.1097/01.ju.0000142827.41910.a2
Zhou, Yufeng, Franklin H. Cocks, Glenn M. Preminger, and Pei Zhong. “Innovations in shock wave lithotripsy technology: updates in experimental studies.J Urol 172, no. 5 Pt 1 (November 2004): 1892–98. https://doi.org/10.1097/01.ju.0000142827.41910.a2.
Zhou Y, Cocks FH, Preminger GM, Zhong P. Innovations in shock wave lithotripsy technology: updates in experimental studies. J Urol. 2004 Nov;172(5 Pt 1):1892–8.
Zhou, Yufeng, et al. “Innovations in shock wave lithotripsy technology: updates in experimental studies.J Urol, vol. 172, no. 5 Pt 1, Nov. 2004, pp. 1892–98. Pubmed, doi:10.1097/01.ju.0000142827.41910.a2.
Zhou Y, Cocks FH, Preminger GM, Zhong P. Innovations in shock wave lithotripsy technology: updates in experimental studies. J Urol. 2004 Nov;172(5 Pt 1):1892–1898.
Journal cover image

Published In

J Urol

DOI

ISSN

0022-5347

Publication Date

November 2004

Volume

172

Issue

5 Pt 1

Start / End Page

1892 / 1898

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Lithotripsy
  • Equipment Design
  • 3202 Clinical sciences
  • 1103 Clinical Sciences