Characterization of shear stress dependent release of nitric oxide from endothelial cells in vitro
Publication
, Journal Article
Kanai, AJ; Strauss, HC; Malinski, T; Truskey, GA
Published in: American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
January 1, 1995
Nitric oxide (NO) is a potent vasodilator released by endothelial cells following exposure to flow. Studies of NO release under well defined flow conditions are necessary in order to understand the kinetics of NO release and the regulation of this process. In the current study, a microsensor placed in the upper chamber of a parallel plate flow channel is used to measure flow-dependent NO release from endothelial cells placed in the lower plate of the chamber. The measured rate of NO release is a function of the intrinsic rate of release, mass transfer across the flow cell, and oxidation of NO in the tissue culture medium.
Duke Scholars
Published In
American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Publication Date
January 1, 1995
Volume
29
Start / End Page
573 / 574
Related Subject Headings
- Biomedical Engineering
Citation
APA
Chicago
ICMJE
MLA
NLM
Kanai, A. J., Strauss, H. C., Malinski, T., & Truskey, G. A. (1995). Characterization of shear stress dependent release of nitric oxide from endothelial cells in vitro. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, 29, 573–574.
Kanai, A. J., H. C. Strauss, T. Malinski, and G. A. Truskey. “Characterization of shear stress dependent release of nitric oxide from endothelial cells in vitro.” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED 29 (January 1, 1995): 573–74.
Kanai AJ, Strauss HC, Malinski T, Truskey GA. Characterization of shear stress dependent release of nitric oxide from endothelial cells in vitro. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1995 Jan 1;29:573–4.
Kanai, A. J., et al. “Characterization of shear stress dependent release of nitric oxide from endothelial cells in vitro.” American Society of Mechanical Engineers, Bioengineering Division (Publication) BED, vol. 29, Jan. 1995, pp. 573–74.
Kanai AJ, Strauss HC, Malinski T, Truskey GA. Characterization of shear stress dependent release of nitric oxide from endothelial cells in vitro. American Society of Mechanical Engineers, Bioengineering Division (Publication) BED. 1995 Jan 1;29:573–574.
Published In
American Society of Mechanical Engineers, Bioengineering Division (Publication) BED
Publication Date
January 1, 1995
Volume
29
Start / End Page
573 / 574
Related Subject Headings
- Biomedical Engineering