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George A. Truskey

R. Eugene and Susie E. Goodson Distinguished Professor of Biomedical Engineering
Biomedical Engineering
Box 90281, Durham, NC 27708-0281
1395 Fciemas, 101 Science Drive, Durham, NC 27708-0281

Overview


My research interests focus upon the effect of physical forces on the function of vascular cells and skeletal muscle, cell adhesion, and the design of engineered tissues.  Current research projects examine the  effect of endothelial cell senescence upon permeability to macromolecules and the response to fluid shear stress, the development of microphysiological blood vessels and muscles for evaluation of drug toxicity and the design of engineered endothelialized blood vessels and skeletal muscle bundles.

Current Appointments & Affiliations


R. Eugene and Susie E. Goodson Distinguished Professor of Biomedical Engineering · 2011 - Present Biomedical Engineering, Pratt School of Engineering
Professor of Biomedical Engineering · 2000 - Present Biomedical Engineering, Pratt School of Engineering
Affiliate of the Duke Initiative for Science & Society · 2014 - Present Duke Science & Society, University Initiatives & Academic Support Units
Affiliate of the Duke Regeneration Center · 2021 - Present Duke Regeneration Center, Basic Science Departments

In the News


Published December 15, 2021
Duke Signs Educational Partnership With U.S. Army 18th Airborne Corps
Published May 10, 2021
University Redoubles Efforts to Convert Research Into Social Impact
Published February 19, 2016
Researchers Have Discovered a Fast Way to Make Artificial Arteries for Testing Drugs

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Recent Publications


Recurrent somatic mutation and progerin expression in early vascular aging of chronic kidney disease.

Journal Article Nat Aging · June 10, 2025 Early vascular aging plays a central role in chronic kidney disease (CKD), but its molecular causes remain unclear. Somatic mutations accumulate in various cells with age, yet their functional contribution to aging tissues is not well understood. Here we f ... Full text Link to item Cite

Development of small tissue engineered blood vessels and their clinical and research applications.

Journal Article Biofabrication · May 2025 Since the first tissue engineered blood vessel (TEBV) was developed, different approaches, biomaterial scaffolds and cell sources have been used to obtain an engineered vessel as much similar as native vessels in terms of structure, functionality and mecha ... Full text Cite
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Recent Grants


Engineering Heterocellular Human Skeletal Muscle Tissues to Recreate and Study Native Stem Cell Niche Function

ResearchCo Investigator · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2024 - 2029

Translational Center for Barrier Microphysiological Systems

ResearchPrincipal Investigator · Awarded by University of Rochester · 2024 - 2028

Stimulating Access to Research in Residency (StARR) - NHLBI

Inst. Training Prgm or CMEPreceptor · Awarded by National Heart, Lung, and Blood Institute · 2018 - 2028

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Education, Training & Certifications


Massachusetts Institute of Technology · 1985 Ph.D.
University of Pennsylvania · 1979 B.S.E.