George A. Truskey
R. Eugene and Susie E. Goodson Distinguished Professor of Biomedical Engineering
My research interests focus upon the effect of physical forces on the function of vascular cells and skeletal muscle, cell adhesion, and the design of engineered tissues. Current research projects examine the effect of endothelial cell senescence upon permeability to macromolecules and the response to fluid shear stress, the development of microphysiological blood vessels and muscles for evaluation of drug toxicity and the design of engineered endothelialized blood vessels and skeletal muscle bundles.
Current Research Interests
Cardiovascular tissue engineering, mechanisms of atherogenesis, cell adhesion, and cell biomechanics.
Current Appointments & Affiliations
- R. Eugene and Susie E. Goodson Distinguished Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2011
- Professor of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2000
- Associate Vice President for Research in the Office of Research, Institutes and Provost's Academic Units, Duke University 2020
- Faculty Network Member of The Energy Initiative, Nicholas Institute-Energy Initiative, Initiatives 2012
- Affiliate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2014
- Affiliate of the Duke Regeneration Center, Regeneration Next Initiative, Basic Science Departments 2021
Contact Information
- 1395 Fciemas, 101 Science Drive, Durham, NC 27708-0281
- Box 90281, Durham, NC 27708-0281
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george.truskey@duke.edu
(919) 660-5147
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Google Scholar
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Truskey Lab Research
- Background
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Education, Training, & Certifications
- Ph.D., Massachusetts Institute of Technology 1985
- B.S.E., University of Pennsylvania 1979
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Previous Appointments & Affiliations
- Senior Associate Dean in the Pratt School of Engineering, Pratt School of Engineering, Duke University 2016 - 2021
- Interim Vinik Dean of Engineering, Pratt School of Engineering, Duke University 2015 - 2016
- Senior Associate Dean for Research, Pratt School of Engineering, Duke University 2014 - 2015
- Senior Associate Dean for Research in the Pratt School of Engineering, Pratt School of Engineering, Duke University 2011 - 2014
- Chair, Department of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2003 - 2011
- Interim Chair, Department of Biomedical Engineering, Biomedical Engineering, Pratt School of Engineering 2000 - 2001
- Associate Professor with Tenure, Biomedical Engineering, Pratt School of Engineering 1994 - 2000
- Assistant Professor, Biomedical Engineering, Pratt School of Engineering 1987 - 1994
- Assistant Professor of Biochemical Engineering, Pratt School of Engineering, Duke University 1987 - 1991
- Recognition
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In the News
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DEC 15, 2021 -
MAY 10, 2021 -
FEB 6, 2020 Pratt School of Engineering -
NOV 1, 2019 Pratt School of Engineering -
SEP 13, 2017 Pratt School of Engineering -
AUG 14, 2017 Pratt School of Engineering -
FEB 26, 2016 Gizmodo -
FEB 26, 2016 Gizmodo -
FEB 18, 2016 Pratt School of Engineering -
JAN 14, 2016 -
JAN 14, 2016 Duke Today -
NOV 24, 2014 -
NOV 24, 2014 Duke Today -
SEP 24, 2014 Pratt School of Engineering
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Awards & Honors
- Fellow. American Association for the Advancement of Science (AAAS). 2015
- AAAS Fellow. American Association for the Advancement of Science. 2014
- BMES Distinguished Service Award. Biomedical Engineering Society. 2012
- NIH CSR College of Reviewers. NIH. 2010
- Capers and Marion McDonald Award for Excellence in Mentoring and Advising. Duke University. 2007
- Fellow. Biomedical Engineering Society. 2006
- Fellow. American Institute for Medical and Biological Engineering. 1999
- Fellow. Council on Arteriosclerosis, Thrombosis and Vascular Biology, American Heart Association. 1999
- Excellence in Teaching Award. Tau Beta Pi, North Carolina Gamma Chapter. 1998
- Outstanding Scientific Paper in the Journal of Parenteral Science and Technology. Parenteral Drug Association. 1987
- Research
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Selected Grants
- Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program awarded by National Institutes of Health 2022 - 2027
- Elucidation of the mechanisms by which cells recognize and respond to different levels of androgens awarded by National Institutes of Health 2022 - 2027
- Staphylococcus aureus Cardiac Device Infections - From the Vascular Viewpoint (K23) awarded by National Institutes of Health 2022 - 2027
- University Training Program in Biomolecular and Tissue Engineering awarded by National Institutes of Health 1994 - 2027
- Hematology & Transfusion Medicine (T32) awarded by National Institutes of Health 1975 - 2026
- In Vitro Human Tissue-Engineered Blood Vessel Disease Model of Progeria awarded by National Institutes of Health 2017 - 2026
- Duke Center for Advancement of Child Health (CAtCH). awarded by National Institutes of Health 2021 - 2026
- Cardiac Device Infection in Microphysiological Vascular Models awarded by American Heart Association 2022 - 2025
- Fabrication of Engineered Blood Vessel Perfusion Chambers awarded by Altos Labs, Inc. 2022 - 2025
- Mechanisms Regulating Vascular Homeostasis awarded by National Institutes of Health 2021 - 2025
- Development of a digital acoustofluidic system for automating liquid handling in biomedical research awarded by National Institutes of Health 2021 - 2025
- Perpetual Organ Preservation and Rehabilitation (POPR) awarded by National Institutes of Health 2022 - 2024
- Atherosclerotic Risk of Branched Chain Amino Acids in a Tissue Engineered Blood Vessel Model awarded by National Institutes of Health 2022 - 2024
- Human Microphysiological System to Study LINC Complex Mediated Force Imbalance in Progeria and Cardiovascular Diseases awarded by American Heart Association 2022 - 2023
- Mechanotransduction in Meniscus Health and Repair awarded by National Institutes of Health 2019 - 2023
- Cell-free mitochondrial DNA induces type I interferon production in an experimental myobundle model of juvenile dermatomyositis (JDM). awarded by Cure JM Foundation 2022 - 2023
- Microphysiological Human Tissue Systems for Monitoring of Genome Editing Outcomes awarded by National Institutes of Health 2019 - 2023
- Progeria and Vasculature: Investigating Genetic Effects and the Potential of Genome Editing for Treatment awarded by National Institutes of Health 2020 - 2023
- Duke Resident Physician-Scientist Program- NHLBI awarded by National Institutes of Health 2018 - 2023
- Epigenetic Mechanisms Promoting Longevity awarded by National Institutes of Health 2018 - 2023
- Acquisition of a Biacore T200 Surface Plasmon Resonance Instrument for Shared Use awarded by North Carolina Biotechnology Center 2022 - 2023
- Human Skeletal Muscle Model for Drug Discovery/Validation awarded by Novo Nordisk A/S 2022 - 2023
- Systemic Inflammation in Microphysiological Models of Muscle and Vascular Disease awarded by National Institutes of Health 2017 - 2022
- Faculty Springboard to Advance Breakthrough Science by Post-Tenure Faculty awarded by National Science Foundation 2018 - 2021
- TREK-1 in fibroblast differentiation and cardiac fibrosis development awarded by National Institutes of Health 2015 - 2020
- Ex vivo metabolomic profiling of statin-induced myopathy awarded by American Heart Association 2017 - 2019
- Developing An In Vitro Human Myobundle Model Of Rheumatoid Arthritis awarded by National Institutes of Health 2017 - 2019
- DukeMed Activated awarded by National Institutes of Health 2014 - 2019
- Visualizing and Elucidating Mechanisms of Mechanotransduction in Vascular Smooth Muscle Cells awarded by American Heart Association 2016 - 2018
- Circulatory system and integrated muscle tissue for drug and tissue toxicity awarded by National Institutes of Health 2012 - 2018
- Using Aptamer Coated Nanoparticles Encapsulating Prostate Tumor Antigen Encoding mRNA to Target Dendritic Cells In Vivo awarded by United States Army Medical Research and Materiel Command 2012 - 2018
- Enhanced Design Experiences for Duke BME Students awarded by National Institutes of Health 2011 - 2017
- Effects of Chondroitin Sulfate and Chrondroitin Sulfate/Glucosamine on Muscle Immune Signaling and Function in TNF-alpha Stimulated Three Dimensional Muscle Cultures awarded by Bioiberica, S.A. 2016 - 2017
- TREK-1 in fibroblast differentiation and cardiac fibrosis development awarded by American Heart Association 2014 - 2015
- Endothelial Progenitor Cell Seeded Self-Expanding Vascular Stent awarded by National Institutes of Health 2011 - 2015
- Engineering a Functional Skeletal Muscle awarded by National Institutes of Health 2008 - 2014
- EPC Adhesion to Teflon-AF and ePTFE Vascular Grafts awarded by National Institutes of Health 1990 - 2013
- MicroRNA Mediation of Stretch-Induced Myoblast Function for Engineered Tissues awarded by National Institutes of Health 2009 - 2013
- Endothelial Cell Adhesion and Function on Smooth Muscle awarded by National Institutes of Health 2008 - 2013
- Autologous EPC lining to improve biocompatibility of circulatory assist devices awarded by National Institutes of Health 2009 - 2012
- Investigation of Anti-Angiogenic Mechanisms Using Novel Imaging Techniques awarded by US Army Medical Research and Materiel Command 2009 - 2012
- Optimizing and Evaluating an Integrated SPECT-CmT System Dedicated to Improved 3-D Breast Cancer Imaging awarded by United States Army Medical Research and Materiel Command 2008 - 2010
- Breast Cancer Research Program (BCRP) Predoctoral Traineeship Award awarded by United States Army Medical Research and Materiel Command 2007 - 2010
- Breast Cancer Research Program (BCRP) Predoctoral Traineeship Award awarded by United States Army Medical Research and Materiel Command 2006 - 2009
- Automation and Preclinical Evaluation of a Dedicated Emission Mammotomography System for Fully 3-D Molecular Breast Imaging awarded by United States Army Medical Research and Materiel Command 2006 - 2009
- Function of Endothelial Cell Integrins in Co-Culture awarded by National Institutes of Health 2007 - 2009
- Training in Biomolecular and Tissue Engineering awarded by National Institutes of Health 2003 - 2009
- Early Detection of Breast Cancer via Multi-Plane Correlation Breast Imaging awarded by United States Army Medical Research and Materiel Command 2006 - 2009
- Computer Aided Detection of Breast Masses in Digital Tomosynthesis awarded by United States Army Medical Research and Materiel Command 2005 - 2008
- Flow Effects on Endothelial-Monocycle Interactions awarded by National Institutes of Health 2003 - 2008
- Computer-Aided Diagnosis System for Breast Cancer Combining Digital Mammography and Genomics awarded by United States Army Medical Research and Materiel Command 2005 - 2008
- Optimization and Compression of Different Digital Mammographic Tomosynthesis Reconstruction Methods awarded by United States Army Medical Research and Materiel Command 2006 - 2008
- Image Processing and Computer Aided Diagnosis in Computed Tomography of the Breast awarded by United States Army Medical Research and Materiel Command 2005 - 2008
- Image Processing and Computer Aided Diagnosis in Computed Tomography of the Breast awarded by United States Army Medical Research and Materiel Command 2005 - 2008
- Endothelial Cell Adhesion to Polymers Studied by TIRF awarded by National Institutes of Health 1990 - 2008
- Endothelial Cell Adhesion to Polymers Studied by TIRF awarded by National Institutes of Health 1990 - 2008
- Mechanical Stimulation of 2- and 3-D Myoblast Culture awarded by National Institutes of Health 2003 - 2007
- Mechanical Stimulation of 2- and 3D Myoblast Culture awarded by National Institutes of Health 2003 - 2007
- Flow Effects on Endothelial-Monocyte Interactions awarded by National Institutes of Health 2003 - 2007
- Flow Effects on Endothelial-Monocyte Interactions awarded by National Institutes of Health 2003 - 2007
- Development of a New Course: Design Projects in Cellular and Biomolecular Engineering awarded by Lord Foundation of North Carolina 2004 - 2006
- Student Design for People with Disabilities awarded by Lord Foundation of North Carolina 2004 - 2006
- Endothelial-Smooth Muscle Cell Interactions in Coculture awarded by National Institutes of Health 2002 - 2006
- A Colorimetric Colloidal Gold Sensor to Interrogate Biomolecular Interactions in Real-time on a Surface awarded by Lord Foundation of North Carolina 2003 - 2005
- Advanced Interconnect Laboratory awarded by Lord Foundation of North Carolina 2003 - 2005
- Fabrication of Metal Nanoarray on Periodically Alligned DNA Template awarded by Lord Foundation of North Carolina 2003 - 2005
- Infrared Spectroscopic Characterization of Melanins and Melanin-Containing Tissues and Development of a Non-Invasive Diagnostic Profile for Malignant Melanoma awarded by Lord Foundation of North Carolina 2003 - 2005
- Endothelial Cell Adhesion to Polymers Studied by TIRF awarded by National Heart, Lung, and Blood Institute 1999 - 2004
- Monocyte and LDL Dynamics During Early Atherogenesis awarded by National Heart, Lung, and Blood Institute 1988 - 2004
- Differentiation and maintenance of skeletal and cardiac muscle in simulated microgravity awarded by National Aeronautics and Space Administration 1999 - 2003
- Sickle Cell Adhesion awarded by National Institutes of Health 1997 - 2003
- 2001 Annual Fall Meeting of the Biomedical Engineering Society awarded by National Institutes of Health 2001 - 2002
- Graduate Student Research Proposal for Amy Collinsworth (Cytoskeletal Contributions to Changes in Elasticity of Mammalian Myocytes After Cyclic Mechanical Loading) awarded by National Aeronautics and Space Administration 1999 - 2001
- Flow Effect on Monocyte/Endothelial Cell Interaction awarded by National Institutes of Health 1998 - 2001
- Effect of Flow on Monocyte-endothelial Cell Interactions awarded by National Institutes of Health 1998 - 2000
- Laboratories in Biomolecular and Cellular Engineering awarded by Division of Undergraduate Education 1998 - 2000
- Endothelial Cell Adhesion to Polymers Studied by TIRF awarded by National Heart, Lung, and Blood Institute (NHLBI) 1990 - 2000
- same awarded by National Aeronautics and Space Administration 1995 - 1999
- Department of Biomedical Engineering Laboratory Upgrade, BME 101, 163, and 164 awarded by Lord Foundation of North Carolina 1998 - 1999
- LDL Transport in Arteries Following Endothelial Injury awarded by National Institutes of Health 1988 - 1999
- LDL Transport in Arteries Following Endothelial Injury awarded by National Institutes of Health 1988 - 1999
- Shear Stress and Calcium and Endothelial NO Release awarded by National Institutes of Health 1996 - 1998
- Shear Stress and Calcium and Endothelial NO Release awarded by National Institutes of Health 1996 - 1998
- Cell Shape and Growth Regulation by Micro-patterned Surfaces awarded by National Science Foundation 1995 - 1998
- Regulation Of Skeletal Muscle Development And Differentiat awarded by National Aeronautics and Space Administration 1995 - 1997
- LDL Transport in Arteries Following Endothelial Injury awarded by National Institutes of Health 1996 - 1997
- Endothelial Cell Adhesion to Polymers Studied by TIRF awarded by National Institutes of Health 1990 - 1996
- Endothelial Cell Adhesion to Polymers Studied by TIRF awarded by National Heart, Lung, and Blood Institute (NHLBI) 1990 - 1996
- Renovation of Room PO13 Teer awarded by Lord Foundation of North Carolina 1995 - 1996
- Hemodynamics and LDL Permeability in the Arterial Wall awarded by National Institutes of Health 1988 - 1993
- Hemodynamics and LDL Permeability in the Arterial Wall awarded by National Institutes of Health 1988 - 1993
- Hemodynamics and LDL Permeability in the Arterial Wall awarded by National Institutes of Health 1988 - 1993
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External Relationships
- Altos Labs
- Publications & Artistic Works
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Selected Publications
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Books
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Truskey, G. A., Yuan, F., & Katz, D. F. (2009). Transport Phenomena in Biological Systems. Pearson Prenticee Hall.
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Academic Articles
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Torres, M. J., Zhang, X., Slentz, D. H., Koves, T. R., Patel, H., Truskey, G. A., & Muoio, D. M. (2022). Chemotherapeutic drug screening in 3D-Bioengineered human myobundles provides insight into taxane-induced myotoxicities. Iscience, 25(10), 105189. https://doi.org/10.1016/j.isci.2022.105189Full Text Open Access Copy Link to Item
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Bishawi, M., Lee, F. H., Abraham, D. M., Glass, C., Blocker, S. J., Cox, D. J., … Bowles, D. E. (2022). Late onset cardiovascular dysfunction in adult mice resulting from galactic cosmic ray exposure. Iscience, 25(4), 104086. https://doi.org/10.1016/j.isci.2022.104086Full Text Link to Item
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Aydin, O., Passaro, A. P., Raman, R., Spellicy, S. E., Weinberg, R. P., Kamm, R. D., … Weiss, R. (2022). Principles for the design of multicellular engineered living systems. Apl Bioengineering, 6(1), 010903. https://doi.org/10.1063/5.0076635Full Text
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Oliver, C. E., Patel, H., Hong, J., Carter, J., Kraus, W. E., Huffman, K. M., & Truskey, G. A. (2022). Tissue engineered skeletal muscle model of rheumatoid arthritis using human primary skeletal muscle cells. J Tissue Eng Regen Med, 16(2), 128–139. https://doi.org/10.1002/term.3266Full Text Link to Item
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Vann, C. G., Zhang, X., Khodabukus, A., Orenduff, M. C., Chen, Y.-H., Corcoran, D. L., … Kraus, V. B. (2022). Differential microRNA profiles of intramuscular and secreted extracellular vesicles in human tissue-engineered muscle. Front Physiol, 13, 937899. https://doi.org/10.3389/fphys.2022.937899Full Text Link to Item
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Zhang, X., Abutaleb, N. O., Salmon, E., & Truskey, G. A. (2022). In Situ Fabrication and Perfusion of Tissue-Engineered Blood Vessel Microphysiological System. Methods in Molecular Biology (Clifton, N.J.), 2375, 77–90. https://doi.org/10.1007/978-1-0716-1708-3_7Full Text
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Zhang, Q., Bosch-Rué, È., Pérez, R. A., & Truskey, G. A. (2021). Biofabrication of tissue engineering vascular systems. Apl Bioengineering, 5(2), 021507. https://doi.org/10.1063/5.0039628Full Text
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Abutaleb, N. O., & Truskey, G. A. (2021). Differentiation and characterization of human iPSC-derived vascular endothelial cells under physiological shear stress. Star Protocols, 2(2), 100394. https://doi.org/10.1016/j.xpro.2021.100394Full Text
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Lee, J. H., Chen, Z., He, S., Zhou, J., Tsai, A., Truskey, G., & Leong, K. W. (2021). Emulating Early Atherosclerosis in a Vascular Microphysiological System Using Branched Tissue-Engineered Blood Vessels. Advanced Biology, 5(4), e2000428. https://doi.org/10.1002/adbi.202000428Full Text
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Saha, K., Sontheimer, E. J., Brooks, P. J., Dwinell, M. R., Gersbach, C. A., Liu, D. R., … SCGE Consortium, . (2021). The NIH Somatic Cell Genome Editing program. Nature, 592(7853), 195–204. https://doi.org/10.1038/s41586-021-03191-1Full Text Link to Item
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Kennedy, C. C., Brown, E. E., Abutaleb, N. O., & Truskey, G. A. (2021). Development and Application of Endothelial Cells Derived From Pluripotent Stem Cells in Microphysiological Systems Models. Frontiers in Cardiovascular Medicine, 8, 625016. https://doi.org/10.3389/fcvm.2021.625016Full Text Open Access Copy
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Kondash, M. E., Ananthakumar, A., Khodabukus, A., Bursac, N., & Truskey, G. A. (2020). Glucose Uptake and Insulin Response in Tissue-engineered Human Skeletal Muscle. Tissue Engineering and Regenerative Medicine, 17(6), 801–813. https://doi.org/10.1007/s13770-020-00242-yFull Text
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Zhang, X., Bishawi, M., Zhang, G., Prasad, V., Salmon, E., Breithaupt, J. J., … Truskey, G. A. (2020). Modeling early stage atherosclerosis in a primary human vascular microphysiological system. Nature Communications, 11(1), 5426. https://doi.org/10.1038/s41467-020-19197-8Full Text
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Salmon, E. E., Breithaupt, J. J., & Truskey, G. A. (2020). Application of Oxidative Stress to a Tissue-Engineered Vascular Aging Model Induces Endothelial Cell Senescence and Activation. Cells, 9(5), E1292. https://doi.org/10.3390/cells9051292Full Text
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Truskey, G. A., & Fu, J. (2020). The future of biomedical engineering: Bioengineering of organoids and tissue development. Current Opinion in Biomedical Engineering, 13, A1–A2. https://doi.org/10.1016/j.cobme.2020.07.002Full Text
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Abutaleb, N. O., & Truskey, G. A. (2020). Human iPSCs Stretch to Improve Tissue-Engineered Vascular Grafts. Cell Stem Cell, 26(2), 136–137. https://doi.org/10.1016/j.stem.2020.01.011Full Text
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Atchison, L., Abutaleb, N. O., Snyder-Mounts, E., Gete, Y., Ladha, A., Ribar, T., … Truskey, G. A. (2020). iPSC-Derived Endothelial Cells Affect Vascular Function in a Tissue-Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome. Stem Cell Reports, 14(2), 325–337. https://doi.org/10.1016/j.stemcr.2020.01.005Full Text
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Ananthakumar, A., Liu, Y., Fernandez, C. E., Truskey, G. A., & Voora, D. (2020). Modeling statin myopathy in a human skeletal muscle microphysiological system. Plos One, 15(11), e0242422. https://doi.org/10.1371/journal.pone.0242422Full Text Link to Item
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Lin, L., Xu, H., Bishawi, M., Feng, F., Samy, K., Truskey, G., … Brennan, T. V. (2019). Circulating mitochondria in organ donors promote allograft rejection. Am J Transplant, 19(7), 1917–1929. https://doi.org/10.1111/ajt.15309Full Text Link to Item
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Davis, B. N. J., Santoso, J. W., Walker, M. J., Oliver, C. E., Cunningham, M. M., Boehm, C. A., … Truskey, G. A. (2019). Modeling the Effect of TNF-α upon Drug-Induced Toxicity in Human, Tissue-Engineered Myobundles. Ann Biomed Eng, 47(7), 1596–1610. https://doi.org/10.1007/s10439-019-02263-8Full Text Link to Item
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Davis, B. N., Yen, R., Prasad, V., & Truskey, G. A. (2019). Oxygen consumption in human, tissue-engineered myobundles during basal and electrical stimulation conditions. Apl Bioengineering, 3(2), 026103. https://doi.org/10.1063/1.5093417Full Text
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Truskey, G. A. (2019). The future of biomedical engineering — digital health. Current Opinion in Biomedical Engineering, 9, A1–A2. https://doi.org/10.1016/j.cobme.2019.04.003Full Text
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Truskey, G. A. (2018). Development and application of human skeletal muscle microphysiological systems. Lab on a Chip, 18(20), 3061–3073. https://doi.org/10.1039/c8lc00553bFull Text
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Zhang, X., Hong, S., Yen, R., Kondash, M., Fernandez, C. E., & Truskey, G. A. (2018). A system to monitor statin-induced myopathy in individual engineered skeletal muscle myobundles. Lab on a Chip, 18(18), 2787–2796. https://doi.org/10.1039/c8lc00654gFull Text
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Chen, Z., Tang, M., Huang, D., Jiang, W., Li, M., Ji, H., … Leong, K. W. (2018). Real-time observation of leukocyte-endothelium interactions in tissue-engineered blood vessel. Lab on a Chip, 18(14), 2047–2054. https://doi.org/10.1039/c8lc00202aFull Text
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Marsden, A. L., & Truskey, G. A. (2018). The future of biomedical engineering – Vascular bioengineering. Current Opinion in Biomedical Engineering, 5, iii–v. https://doi.org/10.1016/j.cobme.2018.04.002Full Text
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Boularaoui, S. M., Abdel-Raouf, K. M. A., Alwahab, N. S. A., Kondash, M. E., Truskey, G. A., Teo, J. C. M., & Christoforou, N. (2018). Efficient transdifferentiation of human dermal fibroblasts into skeletal muscle. Journal of Tissue Engineering and Regenerative Medicine, 12(2), e918–e936. https://doi.org/10.1002/term.2415Full Text
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Truskey, G. A. (2018). Human Microphysiological Systems and Organoids as in Vitro Models for Toxicological Studies. Frontiers in Public Health, 6, 185. https://doi.org/10.3389/fpubh.2018.00185Full Text
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Atchison, L., Zhang, H., Cao, K., & Truskey, G. A. (2017). A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells. Scientific Reports, 7(1), 8168. https://doi.org/10.1038/s41598-017-08632-4Full Text
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Davis, B. N. J., Santoso, J. W., Walker, M. J., Cheng, C. S., Koves, T. R., Kraus, W. E., & Truskey, G. A. (2017). Human, Tissue-Engineered, Skeletal Muscle Myobundles to Measure Oxygen Uptake and Assess Mitochondrial Toxicity. Tissue Eng Part C Methods, 23(4), 189–199. https://doi.org/10.1089/ten.tec.2016.0264Full Text Link to Item
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Truskey, G. A. (2017). The future of biomedical engineering. Current Opinion in Biomedical Engineering, 1, 1–3. https://doi.org/10.1016/j.cobme.2017.04.004Full Text
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Vernetti, L., Gough, A., Baetz, N., Blutt, S., Broughman, J. R., Brown, J. A., … Taylor, D. L. (2017). Corrigendum: Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. Scientific Reports, 7, 44517. https://doi.org/10.1038/srep44517Full Text Open Access Copy
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Vernetti, L., Gough, A., Baetz, N., Blutt, S., Broughman, J. R., Brown, J. A., … Taylor, D. L. (2017). Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle. Scientific Reports, 7, 42296. https://doi.org/10.1038/srep42296Full Text
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Kleinstreuer, C., Hyun, S., Buchanan, J. R., Longest, P. W., Archie, J. P., & Truskey, G. A. (2017). Hemodynamic Parameters and Early Intimal Thickening in Branching Blood Vessels. Critical Reviews in Biomedical Engineering, 45(1–6), 319–382. https://doi.org/10.1615/critrevbiomedeng.v45.i1-6.140Full Text
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Jantzen, A. E., Noviani, M., Mills, J. S., Baker, K. M., Lin, F.-H., Truskey, G. A., & Achneck, H. E. (2016). Point-of-care seeding of nitinol stents with blood-derived endothelial cells. J Biomed Mater Res B Appl Biomater, 104(8), 1658–1665. https://doi.org/10.1002/jbm.b.33510Full Text Link to Item
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Ji, H., Atchison, L., Chen, Z., Chakraborty, S., Jung, Y., Truskey, G. A., … Leong, K. W. (2016). Transdifferentiation of human endothelial progenitors into smooth muscle cells. Biomaterials, 85, 180–194. https://doi.org/10.1016/j.biomaterials.2016.01.066Full Text
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Cheng, C. S., Ran, L., Bursac, N., Kraus, W. E., & Truskey, G. A. (2016). Cell Density and Joint microRNA-133a and microRNA-696 Inhibition Enhance Differentiation and Contractile Function of Engineered Human Skeletal Muscle Tissues. Tissue Eng Part A, 22(7–8), 573–583. https://doi.org/10.1089/ten.TEA.2015.0359Full Text Link to Item
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Peters, E. B., Christoforou, N., Leong, K. W., Truskey, G. A., & West, J. L. (2016). Poly(ethylene glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells. Cellular and Molecular Bioengineering, 9(1), 38–54. https://doi.org/10.1007/s12195-015-0423-6Full Text
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Fernandez, C. E., Yen, R. W., Perez, S. M., Bedell, H. W., Povsic, T. J., Reichert, W. M., & Truskey, G. A. (2016). Human Vascular Microphysiological System for in vitro Drug Screening. Sci Rep, 6, 21579. https://doi.org/10.1038/srep21579Full Text Open Access Copy Link to Item
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Noviani, M., Jamiolkowski, R. M., Grenet, J. E., Lin, Q., Carlon, T. A., Qi, L., … Achneck, H. E. (2016). Point-of-Care Rapid-Seeding Ventricular Assist Device with Blood-Derived Endothelial Cells to Create a Living Antithrombotic Coating. Asaio J, 62(4), 447–453. https://doi.org/10.1097/MAT.0000000000000351Full Text Link to Item
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Truskey, G. A. (2016). Advancing cardiovascular tissue engineering. F1000research, 5, F1000FacultyRev-1045. https://doi.org/10.12688/f1000research.8237.1Full Text Open Access Copy
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Jung, Y., Ji, H., Chen, Z., Fai Chan, H., Atchison, L., Klitzman, B., … Leong, K. W. (2015). Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels. Sci Rep, 5, 15116. https://doi.org/10.1038/srep15116Full Text Open Access Copy Link to Item
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Peters, E. B., Liu, B., Christoforou, N., West, J. L., & Truskey, G. A. (2015). Umbilical Cord Blood-Derived Mononuclear Cells Exhibit Pericyte-Like Phenotype and Support Network Formation of Endothelial Progenitor Cells In Vitro. Annals of Biomedical Engineering, 43(10), 2552–2568. https://doi.org/10.1007/s10439-015-1301-zFull Text
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Peters, E. B., Liu, B., Christoforou, N., West, J. L., & Truskey, G. A. (2015). Erratum to: Umbilical Cord Blood-Derived Mononuclear Cells Exhibit Pericyte-Like Phenotype and Support Network Formation of Endothelial Progenitor Cells In Vitro. Annals of Biomedical Engineering, 43(8), 2022. https://doi.org/10.1007/s10439-015-1321-8Full Text
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Truskey, G. A., & Fernandez, C. E. (2015). Tissue-engineered blood vessels as promising tools for testing drug toxicity. Expert Opinion on Drug Metabolism & Toxicology, 11(7), 1021–1024. https://doi.org/10.1517/17425255.2015.1047342Full Text
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Jamiolkowski, R. M., Kang, S. D., Rodriguez, A. K., Haseltine, J. M., Galinat, L. J., Jantzen, A. E., … Achneck, H. E. (2015). Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering. Regenerative Medicine, 10(4), 447–460. https://doi.org/10.2217/rme.15.2Full Text
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Cheung, T. M., Yan, J. B., Fu, J. J., Huang, J., Yuan, F., & Truskey, G. A. (2015). Endothelial Cell Senescence Increases Traction Forces due to Age-Associated Changes in the Glycocalyx and SIRT1. Cellular and Molecular Bioengineering, 8(1), 63–75. https://doi.org/10.1007/s12195-014-0371-6Full Text
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Madden, L., Juhas, M., Kraus, W. E., Truskey, G. A., & Bursac, N. (2015). Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs. Elife, 4, e04885. https://doi.org/10.7554/eLife.04885Full Text Open Access Copy Link to Item
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Peters, E. B., Christoforou, N., Moore, E., West, J. L., & Truskey, G. A. (2015). CD45+ Cells Present Within Mesenchymal Stem Cell Populations Affect Network Formation of Blood-Derived Endothelial Outgrowth Cells. Bioresearch Open Access, 4(1), 75–88. https://doi.org/10.1089/biores.2014.0029Full Text Open Access Copy
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Cheng, C. S., Davis, B. N. J., Madden, L., Bursac, N., & Truskey, G. A. (2014). Physiology and metabolism of tissue-engineered skeletal muscle. Experimental Biology and Medicine (Maywood, N.J.), 239(9), 1203–1214. https://doi.org/10.1177/1535370214538589Full Text
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Cheng, C. S., El-Abd, Y., Bui, K., Hyun, Y.-E., Hughes, R. H., Kraus, W. E., & Truskey, G. A. (2014). Conditions that promote primary human skeletal myoblast culture and muscle differentiation in vitro. Am J Physiol Cell Physiol, 306(4), C385–C395. https://doi.org/10.1152/ajpcell.00179.2013Full Text Link to Item
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Fernandez, C. E., Achneck, H. E., Reichert, W. M., & Truskey, G. A. (2014). Biological and engineering design considerations for vascular tissue engineered blood vessels (TEBVs). Current Opinion in Chemical Engineering, 3, 83–90. https://doi.org/10.1016/j.coche.2013.12.001Full Text
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Fernandez, C. E., Obi-onuoha, I. C., Wallace, C. S., Satterwhite, L. L., Truskey, G. A., & Reichert, W. M. (2014). Late-outgrowth endothelial progenitors from patients with coronary artery disease: endothelialization of confluent stromal cell layers. Acta Biomaterialia, 10(2), 893–900. https://doi.org/10.1016/j.actbio.2013.10.004Full Text
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Hong, S., Jung, Y., Yen, R., Chan, H. F., Leong, K. W., Truskey, G. A., & Zhao, X. (2014). Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems. Lab on a Chip, 14(3), 514–521. https://doi.org/10.1039/c3lc51076jFull Text
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Cheung, T. M., & Truskey, G. A. (2013). Aging endothelial cells exhibit decreased response to atheroprotective shear stress. Asme 2013 Summer Bioengineering Conference, Sbc 2013, 1 A. https://doi.org/10.1115/SBC2013-14402Full Text
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Jantzen, A. E., Achneck, H. E., & Truskey, G. A. (2013). Surface projections of titanium substrates increase antithrombotic endothelial function in response to shear stress. Journal of Biomedical Materials Research. Part A, 101(11), 3181–3191. https://doi.org/10.1002/jbm.a.34613Full Text
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Kang, S. D., Carlon, T. A., Jantzen, A. E., Lin, F.-H., Ley, M. M., Allen, J. D., … Achneck, H. E. (2013). Isolation of functional human endothelial cells from small volumes of umbilical cord blood. Annals of Biomedical Engineering, 41(10), 2181–2192. https://doi.org/10.1007/s10439-013-0807-5Full Text
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Cheung, T. M., Ganatra, M. P., Fu, J. J., & Truskey, G. A. (2013). The Effect of Stress-Induced Senescence on Aging Human Cord Blood-Derived Endothelial Cells. Cardiovascular Engineering and Technology, 4(2), 220–230. https://doi.org/10.1007/s13239-013-0128-8Full Text
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Kinev, A. V., Levering, V., Young, K., Ali-Osman, F., Truskey, G. A., Dewhirst, M. W., & Il’yasova, D. (2013). Endothelial colony forming cells (ECFCs) as a model for studying effects of low-dose ionizing radiation: growth inhibition by a single dose. Cancer Invest, 31(5), 359–364. https://doi.org/10.3109/07357907.2013.789903Full Text Link to Item
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Peters, E. B., Christoforou, N., Leong, K. W., & Truskey, G. A. (2013). Comparison of mixed and lamellar coculture spatial arrangements for tissue engineering capillary networks in vitro. Tissue Engineering. Part A, 19(5–6), 697–706. https://doi.org/10.1089/ten.tea.2011.0704Full Text
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Chen, Z., Lessey, E., Berginski, M. E., Cao, L., Li, J., Trepat, X., … Jacobson, K. (2013). Gleevec, an Abl family inhibitor, produces a profound change in cell shape and migration. Plos One, 8(1), e52233. https://doi.org/10.1371/journal.pone.0052233Full Text
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Truskey, G. A., Achneck, H. E., Bursac, N., Chan, H., Cheng, C. S., Fernandez, C., … Zhao, X. (2013). Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing. Stem Cell Res Ther, 4 Suppl 1(Suppl 1), S10. https://doi.org/10.1186/scrt371Full Text Link to Item
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Cheung, T. M., Ganatra, M. P., Peters, E. B., & Truskey, G. A. (2012). Effect of cellular senescence on the albumin permeability of blood-derived endothelial cells. American Journal of Physiology. Heart and Circulatory Physiology, 303(11), H1374–H1383. https://doi.org/10.1152/ajpheart.00182.2012Full Text
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Khismatullin, D. B., & Truskey, G. A. (2012). Leukocyte rolling on P-selectin: a three-dimensional numerical study of the effect of cytoplasmic viscosity. Biophysical Journal, 102(8), 1757–1766. https://doi.org/10.1016/j.bpj.2012.03.018Full Text
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Selgrade, B. P., & Truskey, G. A. (2012). Computational fluid dynamics analysis to determine shear stresses and rates in a centrifugal left ventricular assist device. Artificial Organs, 36(4), E89–E96. https://doi.org/10.1111/j.1525-1594.2011.01416.xFull Text
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Lane, W. O., Jantzen, A. E., Carlon, T. A., Jamiolkowski, R. M., Grenet, J. E., Ley, M. M., … Achneck, H. E. (2012). Parallel-plate flow chamber and continuous flow circuit to evaluate endothelial progenitor cells under laminar flow shear stress. Journal of Visualized Experiments : Jove, (59), 3349. https://doi.org/10.3791/3349Full Text
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Satterwhite, L. L., Shaked, N. T., Cyr, D. D., Telen, M. J., Truskey, G. A., & Wax, A. (2012). Novel optical signature for sickle cell trait red blood cells. Frontiers in Optics, Fio 2012. https://doi.org/10.1364/fio.2012.fw6a.10Full Text
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Jantzen, A. E., Lane, W. O., Gage, S. M., Jamiolkowski, R. M., Haseltine, J. M., Galinat, L. J., … Achneck, H. E. (2011). Use of autologous blood-derived endothelial progenitor cells at point-of-care to protect against implant thrombosis in a large animal model. Biomaterials, 32(33), 8356–8363. https://doi.org/10.1016/j.biomaterials.2011.07.066Full Text Link to Item
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Jantzen, A. E., Lane, W. O., Gage, S. M., Haseltine, J. M., Galinat, L. J., Jamiolkowski, R. M., … Achneck, H. E. (2011). Autologous endothelial progenitor cell-seeding technology and biocompatibility testing for cardiovascular devices in large animal model. Journal of Visualized Experiments : Jove, (55), 3197. https://doi.org/10.3791/3197Full Text
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Cao, L., Wu, A., & Truskey, G. A. (2011). Biomechanical effects of flow and coculture on human aortic and cord blood-derived endothelial cells. Journal of Biomechanics, 44(11), 2150–2157. https://doi.org/10.1016/j.jbiomech.2011.05.024Full Text
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Shaked, N. T., Satterwhite, L. L., Telen, M. J., Truskey, G. A., & Wax, A. (2011). Quantitative microscopy and nanoscopy of sickle red blood cells performed by wide field digital interferometry. J Biomed Opt, 16(3), 030506. https://doi.org/10.1117/1.3556717Full Text Link to Item
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Achneck, H. E., Jamiolkowski, R. M., Jantzen, A. E., Haseltine, J. M., Lane, W. O., Huang, J. K., … Lawson, J. H. (2011). The biocompatibility of titanium cardiovascular devices seeded with autologous blood-derived endothelial progenitor cells: EPC-seeded antithrombotic Ti implants. Biomaterials, 32(1), 10–18. https://doi.org/10.1016/j.biomaterials.2010.08.073Full Text Link to Item
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Jantzen, A. E., Lane, W. O., Gage, S. M., Haseltine, J. M., Galinat, L. J., Jamiolkowski, R. M., … Achneck, H. E. (2011). Autologous endothelial progenitor cell-seeding technology and biocompatibility testing for cardiovascular devices in large animal model. Journal of Visualized Experiments, (55). https://doi.org/10.3791/3197Full Text
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Angelos, M. G., Brown, M. A., Satterwhite, L. L., Levering, V. W., Shaked, N. T., & Truskey, G. A. (2010). Dynamic adhesion of umbilical cord blood endothelial progenitor cells under laminar shear stress. Biophysical Journal, 99(11), 3545–3554. https://doi.org/10.1016/j.bpj.2010.10.004Full Text
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Rhim, C., Cheng, C. S., Kraus, W. E., & Truskey, G. A. (2010). Effect of microRNA modulation on bioartificial muscle function. Tissue Eng Part A, 16(12), 3589–3597. https://doi.org/10.1089/ten.TEA.2009.0601Full Text Open Access Copy Link to Item
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Brown, M. A., Zhang, L., Levering, V. W., Wu, J.-H., Satterwhite, L. L., Brian, L., … Truskey, G. A. (2010). Human umbilical cord blood-derived endothelial cells reendothelialize vein grafts and prevent thrombosis. Arterioscler Thromb Vasc Biol, 30(11), 2150–2155. https://doi.org/10.1161/ATVBAHA.110.207076Full Text Link to Item
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Truskey, G. A. (2010). Endothelial Cell Vascular Smooth Muscle Cell Co-Culture Assay For High Throughput Screening Assays For Discovery of Anti-Angiogenesis Agents and Other Therapeutic Molecules. International Journal of High Throughput Screening, 2010(1), 171–181. https://doi.org/10.2147/ijhts.s13459Full Text
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Wallace, C. S., & Truskey, G. A. (2010). Direct-contact co-culture between smooth muscle and endothelial cells inhibits TNF-alpha-mediated endothelial cell activation. American Journal of Physiology. Heart and Circulatory Physiology, 299(2), H338–H346. https://doi.org/10.1152/ajpheart.01029.2009Full Text
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Pang, Z., Niklason, L. E., & Truskey, G. A. (2010). Porcine endothelial cells cocultured with smooth muscle cells became procoagulant in vitro. Tissue Engineering. Part A, 16(6), 1835–1844. https://doi.org/10.1089/ten.tea.2009.0448Full Text Open Access Copy
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Huang, X., Zauscher, S., Klitzman, B., Truskey, G. A., Reichert, W. M., Kenan, D. J., & Grinstaff, M. W. (2010). Peptide interfacial biomaterials improve endothelial cell adhesion and spreading on synthetic polyglycolic acid materials. Ann Biomed Eng, 38(6), 1965–1976. https://doi.org/10.1007/s10439-010-9986-5Full Text Open Access Copy Link to Item
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Brown, M. A., Wallace, C. S., Angelos, M., & Truskey, G. A. (2009). Characterization of umbilical cord blood-derived late outgrowth endothelial progenitor cells exposed to laminar shear stress. Tissue Engineering. Part A, 15(11), 3575–3587. https://doi.org/10.1089/ten.tea.2008.0444Full Text
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Stroncek, J. D., Grant, B. S., Brown, M. A., Povsic, T. J., Truskey, G. A., & Reichert, W. M. (2009). Comparison of endothelial cell phenotypic markers of late-outgrowth endothelial progenitor cells isolated from patients with coronary artery disease and healthy volunteers. Tissue Eng Part A, 15(11), 3473–3486. https://doi.org/10.1089/ten.TEA.2008.0673Full Text Link to Item
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Stiber, J. A., Zhang, Z.-S., Burch, J., Eu, J. P., Zhang, S., Truskey, G. A., … Rosenberg, P. B. (2008). Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity. Mol Cell Biol, 28(8), 2637–2647. https://doi.org/10.1128/MCB.01601-07Full Text Link to Item
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Khismatullin, D. B., & Truskey, G. A. (2008). Leukocyte rolling on P-selectin: A 3D numerical study of the effects of cell viscosity and microvillar density. Biorheology, 45(1–2), 63–63.Link to Item
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Stiber, ., A, J., Zhang, ., Z-S, ., Burch, ., J, ., … B, P. (2008). Mice Lacking Homer 1Exhibit a Skeletal Myopathy 1 Characterized by Abnormal TRP Channel Activity. Mol. Cell. Biol., 28, 2637–2647.
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Anamelechi, C. C., Clermont, E. E., Brown, M. A., Truskey, G. A., & Reichert, W. M. (2007). Streptavidin binding and endothelial cell adhesion to biotinylated fibronectin. Langmuir : The Acs Journal of Surfaces and Colloids, 23(25), 12583–12588. https://doi.org/10.1021/la702322nFull Text
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Brown, M. A., Wallace, C. S., Anamelechi, C. C., Clermont, E., Reichert, W. M., & Truskey, G. A. (2007). The use of mild trypsinization conditions in the detachment of endothelial cells to promote subsequent endothelialization on synthetic surfaces. Biomaterials, 28(27), 3928–3935. https://doi.org/10.1016/j.biomaterials.2007.05.009Full Text
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Wallace, C. S., Strike, S. A., & Truskey, G. A. (2007). Smooth muscle cell rigidity and extracellular matrix organization influence endothelial cell spreading and adhesion formation in coculture. American Journal of Physiology. Heart and Circulatory Physiology, 293(3), H1978–H1986. https://doi.org/10.1152/ajpheart.00618.2007Full Text
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Mathur, A. B., Reichert, W. M., & Truskey, G. A. (2007). Flow and high affinity binding affect the elastic modulus of the nucleus, cell body and the stress fibers of endothelial cells. Annals of Biomedical Engineering, 35(7), 1120–1130. https://doi.org/10.1007/s10439-007-9288-8Full Text
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Rhim, C., Lowell, D. A., Reedy, M. C., Slentz, D. H., Zhang, S. J., Kraus, W. E., & Truskey, G. A. (2007). Morphology and ultrastructure of differentiating three-dimensional mammalian skeletal muscle in a collagen gel. Muscle Nerve, 36(1), 71–80. https://doi.org/10.1002/mus.20788Full Text Link to Item
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Zhang, S. J., Truskey, G. A., & Kraus, W. E. (2007). Effect of cyclic stretch on beta1D-integrin expression and activation of FAK and RhoA. Am J Physiol Cell Physiol, 292(6), C2057–C2069. https://doi.org/10.1152/ajpcell.00493.2006Full Text Link to Item
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Wallace, C. S., Champion, J. C., & Truskey, G. A. (2007). Adhesion and function of human endothelial cells co-cultured on smooth muscle cells. Annals of Biomedical Engineering, 35(3), 375–386. https://doi.org/10.1007/s10439-006-9230-5Full Text
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McKinney, V. Z., Rinker, K. D., & Truskey, G. A. (2006). Normal and shear stresses influence the spatial distribution of intracellular adhesion molecule-1 expression in human umbilical vein endothelial cells exposed to sudden expansion flow. Journal of Biomechanics, 39(5), 806–817. https://doi.org/10.1016/j.jbiomech.2005.02.002Full Text
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Anamelechi, C. C., Truskey, G. A., & Reichert, W. M. (2005). Mylar and Teflon-AF as cell culture substrates for studying endothelial cell adhesion. Biomaterials, 26(34), 6887–6896. https://doi.org/10.1016/j.biomaterials.2005.04.027Full Text
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Lavender, M. D., Pang, Z., Wallace, C. S., Niklason, L. E., & Truskey, G. A. (2005). A system for the direct co-culture of endothelium on smooth muscle cells. Biomaterials, 26(22), 4642–4653. https://doi.org/10.1016/j.biomaterials.2004.11.045Full Text
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Choi, M. G., Koh, H. S., Kluess, D., O’Connor, D., Mathur, A., Truskey, G. A., … Sung, K.-L. (2005). Effects of titanium particle size on osteoblast functions in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America, 102(12), 4578–4583. https://doi.org/10.1073/pnas.0500693102Full Text
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Chan, B. P., Liu, W., Klitzman, B., Reichert, W. M., & Truskey, G. A. (2005). In vivo performance of dual ligand augmented endothelialized expanded polytetrafluoroethylene vascular grafts. J Biomed Mater Res B Appl Biomater, 72(1), 52–63. https://doi.org/10.1002/jbm.b.30114Full Text Link to Item
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Khismatullin, D. B., & Truskey, G. A. (2005). Three-dimensional numerical simulation of receptor-mediated leukocyte adhesion to surfaces: Effects of cell deformability and viscoelasticity. Physics of Fluids, 17(3). https://doi.org/10.1063/1.1862635Full Text
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Chan, B. P., Reichert, W. M., & Truskey, G. A. (2004). Synergistic effect of shear stress and streptavidin-biotin on the expression of endothelial vasodilator and cytoskeleton genes. Biotechnology and Bioengineering, 88(6), 750–758. https://doi.org/10.1002/bit.20263Full Text
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Rinker, K. D., Kirkpatrick, A. P., Ting-Beall, H. P., Shepherd, R. D., Levin, J. D., Irick, J., … Truskey, G. A. (2004). Linoleic acid increases monocyte deformation and adhesion to endothelium. Atherosclerosis, 177(2), 275–285. https://doi.org/10.1016/j.atherosclerosis.2004.07.017Full Text
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Khismatullin, D. B., & Truskey, G. A. (2004). A 3D numerical study of the effect of channel height on leukocyte deformation and adhesion in parallel-plate flow chambers. Microvascular Research, 68(3), 188–202. https://doi.org/10.1016/j.mvr.2004.07.003Full Text
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Chan, B. P., Reichert, W. M., & Truskey, G. A. (2004). Effect of streptavidin-biotin on endothelial vasoregulation and leukocyte adhesion. Biomaterials, 25(18), 3951–3961. https://doi.org/10.1016/j.biomaterials.2003.10.077Full Text
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Zhang, J. S., Kraus, W. E., & Truskey, G. A. (2004). Stretch-induced nitric oxide modulates mechanical properties of skeletal muscle cells. Am J Physiol Cell Physiol, 287(2), C292–C299. https://doi.org/10.1152/ajpcell.00018.2004Full Text Link to Item
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Chan, B. P., Reichert, W. M., & Truskey, G. A. (2004). Effect of streptavidin RGD mutant on the adhesion of endothelial cells. Biotechnology Progress, 20(2), 566–575. https://doi.org/10.1021/bp034215zFull Text
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Mathur, A. B., Chan, B. P., Truskey, G. A., & Reichert, W. M. (2003). High-affinity augmentation of endothelial cell attachment: long-term effects on focal contact and actin filament formation. Journal of Biomedical Materials Research. Part A, 66(4), 729–737. https://doi.org/10.1002/jbm.a.10581Full Text
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Buchanan, J. R., Kleinstreuer, C., Hyun, S., & Truskey, G. A. (2003). Hemodynamics simulation and identification of susceptible sites of atherosclerotic lesion formation in a model abdominal aorta. Journal of Biomechanics, 36(8), 1185–1196. https://doi.org/10.1016/s0021-9290(03)00088-5Full Text
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Chan, B. P., Chilkoti, A., Reichert, W. M., & Truskey, G. A. (2003). Effect of streptavidin affinity mutants on the integrin-independent adhesion of biotinylated endothelial cells. Biomaterials, 24(4), 559–570. https://doi.org/10.1016/s0142-9612(02)00367-8Full Text
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Longest, P. W., Kleinstreuer, C., Truskey, G. A., & Buchanan, J. R. (2003). Relation between near-wall residence times of monocytes and early lesion growth in the rabbit aorto-celiac junction. Annals of Biomedical Engineering, 31(1), 53–64. https://doi.org/10.1114/1.1531635Full Text
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Mathur, A. B., Truskey, G. A., & Reichert, W. M. (2003). Synergistic effect of high-affinity binding and flow preconditioning on endothelial cell adhesion. Journal of Biomedical Materials Research. Part A, 64(1), 155–163. https://doi.org/10.1002/jbm.a.10403Full Text
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Chan, B. P., Reichert, W. M., & Truskey, G. A. (2002). The effects of streptavidin-biotin exogenous ligands on the endothelium-derived nitric oxide synthase activity. Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings, 1, 716–717.
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Levin, J. D., & Truskey, G. A. (2002). Increased numbers of bonds stabilize adhesion with multiple tethers between endothelium and monocytes. Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings, 1, 351–352.
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Zhang, J., Kraus, W. M., & Truskey, G. A. (2002). The effects of the actin cytoskeleton on the transverse mechanical properties of skeletal muscle cells. Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings, 1, 400–401.
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Collinsworth, A. M., Zhang, S., Kraus, W. E., & Truskey, G. A. (2002). Apparent elastic modulus and hysteresis of skeletal muscle cells throughout differentiation. Am J Physiol Cell Physiol, 283(4), C1219–C1227. https://doi.org/10.1152/ajpcell.00502.2001Full Text Link to Item
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Ogunrinade, O., Kameya, G. T., & Truskey, G. A. (2002). Effect of fluid shear stress on the permeability of the arterial endothelium. Annals of Biomedical Engineering, 30(4), 430–446. https://doi.org/10.1114/1.1467924Full Text
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Truskey, G. A., Barber, K. M., & Rinker, K. D. (2002). Factors influencing the nonuniform localization of monocytes in the arterial wall. Biorheology, 39(3–4), 325–329.
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Buchanan, J. R., Kleinstreuer, C., & Truskey, G. A. (2001). The lagrangian characterization of resting flow in the rabbit abdominal aorta. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 50, 127–128.
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Buchanan, J. R., Kleinstreuer, C., & Truskey, G. A. (2001). Influence of non-planar curvature at the rabbit aorto-celiac junction. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 50, 471–472.
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Truskey, G. A., Li, H., Kait, J., & Irick, J. (2001). Relationship between LDL residence time and macrophage accumulation in the rabbit aorta. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 50, 679–680.
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Mathur, A. B., Collinsworth, A. M., Reichert, W. M., Kraus, W. E., & Truskey, G. A. (2001). Endothelial, cardiac muscle and skeletal muscle exhibit different viscous and elastic properties as determined by atomic force microscopy. J Biomech, 34(12), 1545–1553. https://doi.org/10.1016/s0021-9290(01)00149-xFull Text Link to Item
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Chan, B. P., Truskey, G. A., & Reichert, W. M. (2001). Binding site tryptophan mutant in the high-affinity avidin-biotin complex: Effect on binding affinity and endothelial cell adhesion. Abstracts of Papers of the American Chemical Society, 221, U123–U123.Link to Item
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Mathur, A. B., Inge, E. W., Reichert, W. M., & Truskey, G. A. (2001). Examination of the effect of stress on streptavidin-biotin/integrin-fibronectin bonds at the cell-substrate interface with the AFM-TIRFM. Abstracts of Papers of the American Chemical Society, 221, U347–U348.Link to Item
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Rinker, K. D., Prabhakar, V., & Truskey, G. A. (2001). Effect of contact time and force on monocyte adhesion to vascular endothelium. Biophysical Journal, 80(4), 1722–1732. https://doi.org/10.1016/s0006-3495(01)76143-7Full Text
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Chan, B. P., Truskey, G. A., & Reichert, W. M. (2001). Binding site tryptophan mutant in the high-affinity avidin-biotin complex: Effect on binding affinity and endothelial cell adhesion. Faseb Journal, 15(4), A451–A451.Link to Item
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Slentz, D. H., Truskey, G. A., & Kraus, W. E. (2001). Effects of chronic exposure to simulated microgravity on skeletal muscle cell proliferation and differentiation. In Vitro Cell Dev Biol Anim, 37(3), 148–156. https://doi.org/10.1290/1071-2690(2001)037<0148:EOCETS>2.0.CO;2Full Text Link to Item
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Kleinstreuer, C., Hyun, S., Buchanan, J. R., Longest, P. W., Archie, J. P., & Truskey, G. A. (2001). Hemodynamic parameters and early intimal thickening in branching blood vessels. Critical Reviews in Biomedical Engineering, 29(1), 1–64. https://doi.org/10.1615/critrevbiomedeng.v29.i1.10Full Text
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Mathur, A., Reichert, W., & Truskey, G. (2000). Atomic force and total internal reflection fluorescence microscopy for the study of force transmission in endothelial cells. Annals of Biomedical Engineering, 28(SUPPL. 1).
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Rinker, K. D., Ting-Beall, H. P., Hochmuth, R. M., & Truskey, G. A. (2000). Mechanism of shear force-dependent monocyte adhesion to vascular endothelium. Annals of Biomedical Engineering, 28(SUPPL. 1).
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Collinsworth, A. M., Torgan, C. E., Nagda, S. N., Rajalingam, R. J., Kraus, W. E., & Truskey, G. A. (2000). Orientation and length of mammalian skeletal myocytes in response to a unidirectional stretch. Cell Tissue Res, 302(2), 243–251. https://doi.org/10.1007/s004410000224Full Text Link to Item
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Torgan, C. E., Burge, S. S., Collinsworth, A. M., Truskey, G. A., & Kraus, W. E. (2000). Differentiation of mammalian skeletal muscle cells cultured on microcarrier beads in a rotating cell culture system. Med Biol Eng Comput, 38(5), 583–590. https://doi.org/10.1007/BF02345757Full Text Link to Item
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Mathur, A. B., Truskey, G. A., & Reichert, W. M. (2000). Atomic force and total internal reflection fluorescence microscopy for the study of force transmission in endothelial cells. Biophysical Journal, 78(4), 1725–1735. https://doi.org/10.1016/s0006-3495(00)76724-5Full Text
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Mathur, A. B., Truskey, G. A., & Reichert, W. M. (2000). Total internal reflection microscopy and atomic force microscopy (TIRFM-AFM) to study stress transduction mechanisms in endothelial cells. Critical Reviews in Biomedical Engineering, 28(1–2), 197–202. https://doi.org/10.1615/critrevbiomedeng.v28.i12.340Full Text
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Rinker, K. D., Ting-Beall, H. P., Hochmuth, R. M., & Truskey, G. A. (2000). Mechanism of shear force-dependent monocyte adhesion to vascular endothelium. Annals of Biomedical Engineering, 28(SUPPL 1), 70.
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Burmeister, J. S., McKinney, V. Z., Reichert, W. M., & Truskey, G. A. (1999). Role of endothelial cell-substrate contact area and fibronectin-receptor affinity in cell adhesion to HEMA/EMA copolymers. Journal of Biomedical Materials Research, 47(4), 577–584. https://doi.org/10.1002/(sici)1097-4636(19991215)47:4<577::aid-jbm15>3.0.co;2-sFull Text
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Chan, B. P., Bhat, V. D., Yegnasubramanian, S., Reichert, W. M., & Truskey, G. A. (1999). An equilibrium model of endothelial cell adhesion via integrin-dependent and integrin-independent ligands. Biomaterials, 20(23–24), 2395–2403. https://doi.org/10.1016/s0142-9612(99)00167-2Full Text
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Mathur, A. B., Truskey, G. A., & Reichert, W. M. (1999). Integration of total internal reflection and atomic force microscopy (TIRFM-AFM) to study stress transduction mechanisms in endothelial cells. Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings, 1, 3.
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Rinker, K. D., Prabhakar, V., Osborn, E. A., & Truskey, G. A. (1999). Effect of fluid viscosity and erythrocytes on monocyte adhesion. Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings, 1, 59.
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Buchanan, J. R., Hyun, S., Kleinstreuer, C., & Truskey, G. A. (1999). Local monocyte deposition patterns and elevated permeabilities in the rabbit abdominal aorta. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 42, 477–478.
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Zen, Q., Riddle, M. E., Fong, A. M., Patel, D. D., Paulsen, D. M., Truskey, G., & Telen, M. J. (1999). Identification and characterization of another non-integrin IgSF membrane protein receptor for laminin. Faseb Journal, 13(7), A1360–A1360.Link to Item
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Buchanan, J. R., Kleinstreuer, C., Truskey, G. A., & Lei, M. (1999). Relation between non-uniform hemodynamics and sites of altered permeability and lesion growth at the rabbit aorto-celiac junction. Atherosclerosis, 143(1), 27–40. https://doi.org/10.1016/s0021-9150(98)00264-0Full Text
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Truskey, G. A., Herrmann, R. A., Kait, J., & Barber, K. M. (1999). Focal increases in vascular cell adhesion molecule-1 and intimal macrophages at atherosclerosis-susceptible sites in the rabbit aorta after short-term cholesterol feeding. Arteriosclerosis, Thrombosis, and Vascular Biology, 19(2), 393–401. https://doi.org/10.1161/01.atv.19.2.393Full Text
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Zen, Q., Cottman, M., Truskey, G., Fraser, R., & Telen, M. J. (1999). Critical factors in basal cell adhesion molecule/lutheran-mediated adhesion to laminin. J Biol Chem, 274(2), 728–734. https://doi.org/10.1074/jbc.274.2.728Full Text Link to Item
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Olivier, L. A., Yen, J., Reichert, W. M., & Truskey, G. A. (1999). Short-term cell/substrate contact dynamics of subconfluent endothelial cells following exposure to laminar flow. Biotechnology Progress, 15(1), 33–42. https://doi.org/10.1021/bp980107eFull Text
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Barber, K. M., Pinero, A., & Truskey, G. A. (1998). Effects of recirculating flow on U-937 cell adhesion to human umbilical vein endothelial cells. American Journal of Physiology, 275(2 PART 2).
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Mathur, A. B., Truskey, G. A., & Reichert, W. M. (1998). Integration of total internal reflection microscopy and atomic force microscopy (TIRFM-AFM) to study mechanotransduction in endothelial cells. Critical Reviews in Biomedical Engineering, 26(5), 334–337.
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Bhat, V. D., Truskey, G. A., & Reichert, W. M. (1998). Fibronectin and avidin-biotin as a heterogeneous ligand system for enhanced endothelial cell adhesion. Journal of Biomedical Materials Research, 41(3), 377–385. https://doi.org/10.1002/(sici)1097-4636(19980905)41:3<377::aid-jbm6>3.0.co;2-9Full Text
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Malinauskas, R. A., Sarraf, P., Barber, K. M., & Truskey, G. A. (1998). Association between secondary flow in models of the aorto-celiac junction and subendothelial macrophages in the normal rabbit. Atherosclerosis, 140(1), 121–134. https://doi.org/10.1016/s0021-9150(98)00129-4Full Text
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Barber, K. M., Pinero, A., & Truskey, G. A. (1998). Effects of recirculating flow on U-937 cell adhesion to human umbilical vein endothelial cells. The American Journal of Physiology, 275(2), H591–H599. https://doi.org/10.1152/ajpheart.1998.275.2.h591Full Text
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Barber, K. M., Pinero, A., & Truskey, G. A. (1998). Effects of recirculating flow on U-937 cell adhesion to human umbilical vein endothelial cells. American Journal of Physiology Heart and Circulatory Physiology, 275(2), H591–H599.Link to Item
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Udani, M., Zen, Q., Cottman, M., Leonard, N., Jefferson, S., Daymont, C., … Telen, M. J. (1998). Erratum: (The Journal of Clinical Investigation (June 1998) 101:11 (2550-2558)). Journal of Clinical Investigation, 102(1), 269.
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Sharkawy, A. A., Klitzman, B., Truskey, G. A., & Reichert, W. M. (1998). Engineering the tissue which encapsulates subcutaneous implants. II. Plasma-tissue exchange properties. J Biomed Mater Res, 40(4), 586–597. https://doi.org/10.1002/(sici)1097-4636(19980615)40:4<586::aid-jbm10>3.0.co;2-eFull Text Link to Item
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Sharkawy, A. A., Klitzman, B., Truskey, G. A., & Reichert, W. M. (1998). Engineering the tissue which encapsulates subcutaneous implants. III. Effective tissue response times. J Biomed Mater Res, 40(4), 598–605. https://doi.org/10.1002/(sici)1097-4636(19980615)40:4<598::aid-jbm11>3.0.co;2-cFull Text Link to Item
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Udani, M., Zen, Q., Cottman, M., Leonard, N., Jefferson, S., Daymont, C., … Telen, M. J. (1998). Basal cell adhesion molecule/lutheran protein. The receptor critical for sickle cell adhesion to laminin. J Clin Invest, 101(11), 2550–2558. https://doi.org/10.1172/JCI1204Full Text Link to Item
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Bhat, V. D., Truskey, G. A., & Reichert, W. M. (1998). Using avidin-mediated binding to enhance initial endothelial cell attachment and spreading. Journal of Biomedical Materials Research, 40(1), 57–65. https://doi.org/10.1002/(sici)1097-4636(199804)40:1<57::aid-jbm7>3.0.co;2-qFull Text
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Burmeister, J. S., Olivier, L. A., Reichert, W. M., & Truskey, G. A. (1998). Application of total internal reflection fluorescence microscopy to study cell adhesion to biomaterials. Biomaterials, 19(4–5), 307–325. https://doi.org/10.1016/s0142-9612(97)00109-9Full Text
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Bhat, V. D., Klitzman, B., Koger, K., Truskey, G. A., & Reichert, W. M. (1998). Improving endothelial cell adhesion to vascular graft surfaces: clinical need and strategies. J Biomater Sci Polym Ed, 9(11), 1117–1135. https://doi.org/10.1163/156856298x00686Full Text Link to Item
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Mathur, A. B., Truskey, G. A., & Reichert, W. M. (1998). Integration of total internal reflection microscopy and atomic force microscopy (TIRFM-AFM) to study mechanotransduction in endothelial cells. Critical Reviews in Biomedical Engineering, 26(5–6), 334–337.
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Sharkawy, A. A., Klitzman, B., Truskey, G. A., & Reichert, W. M. (1997). Engineering the tissue which encapsulates subcutaneous implants. I. Diffusion properties. J Biomed Mater Res, 37(3), 401–412. https://doi.org/10.1002/(sici)1097-4636(19971205)37:3<401::aid-jbm11>3.0.co;2-eFull Text Link to Item
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Herrmann, R. A., Kait, J., & Truskey, G. A. (1997). Spatial distribution of VCAM-1 positive endothelium and intimal macrophages during early hypercholesterolemia. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 35, 23–24.
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Xiao, Y., & Truskey, G. A. (1997). Effect of flow recirculation upon endothelial cell height and shape. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 35, 537–538.
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Collinsworth, A. M., Torgan, C. E., Nagda, S. N., Spivey, E. C., Kraus, W. E., & Truskey, G. A. (1997). The orientation of mammalian skeletal muscle followlng a unidirectional stretch. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 35, 275–276.
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Zen, Q., Udani, M., Cottman, M., Fraser, R., Truskey, G., & Telen, M. J. (1997). B-CAM/LU protein: A single IgSF domain and copy number but not the cytoplasmic region are critical for laminin binding. Blood, 90(10), 2685–2685.Link to Item
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Bhat, V. D., Truskey, G. A., & Reichert, W. M. (1997). Avidin-biotin as an extrinsic, high affinity receptor-ligand system to enhance initial cell attachment and spreading. Abstracts of Papers of the American Chemical Society, 213, 357-COLL.Link to Item
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Xiao, Y., & Truskey, G. A. (1996). Effect of receptor-ligand affinity on the strength of endothelial cell adhesion. Biophysical Journal, 71(5), 2869–2884. https://doi.org/10.1016/s0006-3495(96)79484-5Full Text
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Kanai, A. J., Malinski, T., Birder, L. A., Truskey, G. A., & Finkel, M. S. (1996). Constitutive nitric oxide release from vascular endothelial cells, cardiac myocytes and neurons. Circulation, 94(8), 2026–2026.Link to Item
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Lei, M., Kleinstreuer, C., & Truskey, G. A. (1996). A focal stress gradient-dependent mass transfer mechanism for atherogenesis in branching arteries. Medical Engineering & Physics, 18(4), 326–332. https://doi.org/10.1016/1350-4533(95)00045-3Full Text
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Burmeister, J. S., Vrany, J. D., Reichert, W. M., & Truskey, G. A. (1996). Effect of fibronectin amount and conformation on the strength of endothelial cell adhesion to HEMA/EMA copolymers. Journal of Biomedical Materials Research, 30(1), 13–22. https://doi.org/10.1002/(sici)1097-4636(199601)30:1<13::aid-jbm3>3.0.co;2-uFull Text
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Kanai, A. J., Strauss, H. C., Truskey, G. A., Crews, A. L., Grunfeld, S., & Malinski, T. (1995). Shear stress induces ATP-independent transient nitric oxide release from vascular endothelial cells, measured directly with a porphyrinic microsensor. Circulation Research, 77(2), 284–293. https://doi.org/10.1161/01.res.77.2.284Full Text
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Lei, M., Kleinstreuer, C., & Truskey, G. A. (1995). Numerical investigation and prediction of atherogenic sites in branching arteries. Journal of Biomechanical Engineering, 117(3), 350–357. https://doi.org/10.1115/1.2794191Full Text
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Malinauskas, R. A., Herrmann, R. A., & Truskey, G. A. (1995). The distribution of intimal white blood cells in the normal rabbit aorta. Atherosclerosis, 115(2), 147–163. https://doi.org/10.1016/0021-9150(94)05497-7Full Text
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Truskey, G. A., Barber, K. M., Robey, T. C., Olivier, L. A., & Combs, M. P. (1995). Characterization of a sudden expansion flow chamber to study the response of endothelium to flow recirculation. Journal of Biomechanical Engineering, 117(2), 203–210. https://doi.org/10.1115/1.2796002Full Text
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Kanai, A. J., Strauss, H. C., Malinski, T., & Truskey, G. A. (1995). Characterization of shear stress dependent release of nitric oxide from endothelial cells in vitro. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 29, 573–574.
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Olivier, L. A., Reichert, W. M., & Truskey, G. A. (1995). Dynamic response of endothelial cells to flow as measured by total internal reflectance fluorescence microscopy. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 29, 565–566.
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Truskey, G. A., Herrmann, R. A., & Malinauskas, R. A. (1995). Low density lipoprotein transport in the arterial wall of normal and hypercholesterolemic rabbits. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 29, 129–130.
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Herrmann, R. A., Malinauskas, R. A., & Truskey, G. A. (1994). Characterization of sites with elevated LDL permeability at intercostal, celiac, and iliac branches of the normal rabbit aorta. Arteriosclerosis and Thrombosis : A Journal of Vascular Biology, 14(2), 313–323. https://doi.org/10.1161/01.atv.14.2.313Full Text
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Banovac, F., Saavedra, S. S., & Truskey, G. A. (1994). Local conformational changes of vitronectin upon adsorption on glass and silane surfaces. Journal of Colloid and Interface Science, 165(1), 31–40. https://doi.org/10.1006/jcis.1994.1202Full Text
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Burmeister, J. S., Truskey, G. A., & Reichert, W. M. (1994). Quantitative analysis of variable-angle total internal reflection fluorescence microscopy (VA-TIRFM) of cell/substrate contacts. Journal of Microscopy, 173(Pt 1), 39–51. https://doi.org/10.1111/j.1365-2818.1994.tb03426.xFull Text
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Burmeister, J. S., Truskey, G. A., Yarbrough, J. L., & Reichert, W. M. (1994). Imaging of cell/substrate contacts on polymers by total internal reflection fluorescence microscopy. Biotechnology Progress, 10(1), 26–31. https://doi.org/10.1021/bp00025a003Full Text
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Olivier, L. A., & Truskey, G. A. (1993). A numerical analysis of forces exerted by laminar flow on spreading cells in a parallel plate flow chamber assay. Biotechnology and Bioengineering, 42(8), 963–973. https://doi.org/10.1002/bit.260420807Full Text
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Iuliano, D. J., Saavedra, S. S., & Truskey, G. A. (1993). Effect of the conformation and orientation of adsorbed fibronectin on endothelial cell spreading and the strength of adhesion. Journal of Biomedical Materials Research, 27(8), 1103–1113. https://doi.org/10.1002/jbm.820270816Full Text
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Truskey, G. A., & Proulx, T. L. (1993). Relationship between 3T3 cell spreading and the strength of adhesion on glass and silane surfaces. Biomaterials, 14(4), 243–254. https://doi.org/10.1016/0142-9612(93)90114-hFull Text
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du Laney, T. V., Cherry, R. S., Coppinger, J. A., & Truskey, G. A. (1992). Altered distribution of mitochondria and actin fibers in 3T3 cells cultured on microcarriers. Biotechnology Progress, 8(6), 572–575. https://doi.org/10.1021/bp00018a600Full Text
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Truskey, G. A., Roberts, W. L., Herrmann, R. A., & Malinauskas, R. A. (1992). Measurement of endothelial permeability to 125I-low density lipoproteins in rabbit arteries by use of en face preparations. Circulation Research, 71(4), 883–897. https://doi.org/10.1161/01.res.71.4.883Full Text
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Truskey, G. A., Burmeister, J. S., Grapa, E., & Reichert, W. M. (1992). Total internal reflection fluorescence microscopy (TIRFM). II. Topographical mapping of relative cell/substratum separation distances. Journal of Cell Science, 103 ( Pt 2), 491–499. https://doi.org/10.1242/jcs.103.2.491Full Text
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BURMEISTER, J. S., REICHERT, W. M., & TRUSKEY, G. A. (1992). MEASUREMENT OF CELL CONTACT AREA ON FIBRONECTIN-COATED SURFACES BY VARIABLE ANGLE TOTAL INTERNAL-REFLECTION FLUORESCENCE MICROSCOPY (TIRFM). Abstracts of Papers of the American Chemical Society, 204, 17-COLL.Link to Item
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Garrison, M. D., Iuliano, D. J., Saavedra, S. S., Truskey, G. A., & Reichert, W. M. (1992). Postadsorption changes in the emission maximum of acrylodan-labeled bovine serum albumin using total internal reflection fluorescence. Journal of Colloid and Interface Science, 148(2), 415–424. https://doi.org/10.1016/0021-9797(92)90180-TFull Text
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TRUSKEY, G. A. (1992). Total internal reflection fluorescence microscopy (TIRFM). II. Topographical mapping of relative cell/substratum separation distances. J Cell Sci, 103, 491–499.
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Burmeister, J., Truskey, G. A., & Reichert, W. M. (1991). Variable angle total internal reflection fluorescence (TIRF) microscopy of fluorescently labelled lipid films and cells at the glass-liquid interface. Annals of Biomedical Engineering, 19(5), 614.
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Herrmann, R. A., Malinauskas, R. A., & Truskey, G. A. (1991). Regional variations in endothelial permeability to 125I-low density lipoproteins in rabbit arteries. Annals of Biomedical Engineering, 19(5), 606.
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Olivier, L. A., & Truskey, G. A. (1991). Numerical simulation of forces on a spreading cell exposed to flow. Annals of Biomedical Engineering, 19(5), 607.
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Iuliano, D. J., Proulx, T. L., Saavedra, S. S., & Truskey, G. A. (1991). Role of adhesion proteins and cytoskeleton in the short-term response of fibroblasts and endothelial cells to steady laminar flow. American Society of Mechanical Engineers, Bioengineering Division (Publication) Bed, 21, 23–25.
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HERRMANN, R. A., ROBERTS, W. L., MALINAUSKAS, R. A., & TRUSKEY, G. A. (1991). FOCAL REGIONS OF INCREASED ARTERIAL PERMEABILITY TO LOW-DENSITY-LIPOPROTEIN (LDL) INVIVO MEASURED BY AUTORADIOGRAPHY. Faseb Journal, 5(5), A1251–A1251.Link to Item
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TRUSKEY, G. A., IULIANO, D. J., & SAAVEDRA, S. S. (1991). THE EFFECT OF THE CONFORMATION OF ADSORBED FIBRONECTIN (FN) ON ENDOTHELIAL-CELL ADHESION. Faseb Journal, 5(4), A372–A372.Link to Item
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Truskey, G. A., & Proulx, T. L. (1990). Quantitation of cell area on glass and fibronectin-coated surfaces by digital image analysis. Biotechnology Progress, 6(6), 513–519. https://doi.org/10.1021/bp00006a016Full Text
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Truskey, G. A., & Pirone, J. S. (1990). The effect of fluid shear stress upon cell adhesion to fibronectin-treated surfaces. Journal of Biomedical Materials Research, 24(10), 1333–1353. https://doi.org/10.1002/jbm.820241006Full Text
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Truskey, G. A., Nicolakis, D. P., DiMasi, D., Haberman, A., & Swartz, R. W. (1990). Kinetic studies and unstructured models of lymphocyte metabolism in fed-batch culture. Biotechnology and Bioengineering, 36(8), 797–807. https://doi.org/10.1002/bit.260360807Full Text
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TRUSKEY, G. A., REICHERT, W. M., & GRAPA, E. (1990). A METHOD TO MEASURE CELL-SEPARATION DISTANCES USING TOTAL INTERNAL-REFLECTION FLUORESCENCE. Abstracts of Papers of the American Chemical Society, 200, 155-BIOT.Link to Item
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Reichert, W. M., & Truskey, G. A. (1990). Total internal reflection fluorescence (TIRF) microscopy. I. Modelling cell contact region fluorescence. Journal of Cell Science, 96 ( Pt 2), 219–230. https://doi.org/10.1242/jcs.96.2.219Full Text
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Truskey, G. A., Gabler, R., DiLeo, A., & Manter, T. (1987). The effect of membrane filtration upon protein conformation. Journal of Parenteral Science and Technology : A Publication of the Parenteral Drug Association, 41(6), 180–193.
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Davies, P. F., Truskey, G. A., Warren, H. B., O’Connor, S. E., & Eisenhaure, B. H. (1985). Metabolic cooperation between vascular endothelial cells and smooth muscle cells in co-culture: changes in low density lipoprotein metabolism. The Journal of Cell Biology, 101(3), 871–879. https://doi.org/10.1083/jcb.101.3.871Full Text
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Truskey, G. A., & Davies, P. F. (1985). Effects of ammonium ion derived from bovine endothelial cells upon low density lipoprotein degradation in cultured vascular smooth muscle cells. Cell Biology International Reports, 9(4), 323–330. https://doi.org/10.1016/0309-1651(85)90027-xFull Text
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TRUSKEY, G. A., COLTON, C. K., & DAVIES, P. F. (1984). Kinetic Analysis of Receptor‐Mediated Endocytosis and Lysosomal Degradation in Cultured Cells. Annals of the New York Academy of Sciences, 435(1), 349–351. https://doi.org/10.1111/j.1749-6632.1984.tb13817.xFull Text
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Book Sections
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Kondash, M. E., Davis, B. N. J., & Truskey, G. A. (2017). Optimizing 3D models of engineered skeletal muscle. In Engineering 3D Tissue Test Systems (pp. 321–350). https://doi.org/10.1201/9781315118260Full Text
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Cheung, T. M., & Truskey, G. A. (2015). Environmental Factors that Influence the Response of the Endothelium to Flow. In H. Aranda-Espinoza (Ed.), Mechanobiology of the Endothelium (pp. 103–131). CRC Press. https://doi.org/10.1201/b18060-6Full Text
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Cheung, T. M., & Truskey, G. A. (2015). Environmental factors that influence the response of the endothelium to flow. In Mechanobiology of the Endothelium (pp. 103–131). https://doi.org/10.1201/b18060Full Text
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Brown, M. A., Cheng, C. S., & Truskey, G. A. (2011). Endothelial progenitor cells for vascular repair. In Stem Cell Engineering: Principles and Applications (pp. 297–320). https://doi.org/10.1007/978-3-642-11865-4_13Full Text
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Other Articles
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Sharkawy, A., Klitzman, B., Truskey, G., & Reichert, W. (1997). Diffusion properties of tissue which encapsulates subcutaneous implants. Abstracts of Papers of the American Chemical Society. AMER CHEMICAL SOC.Link to Item
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Sharkawy, A., Klitzman, B., Truskey, G., & Reichert, W. (1997). Diffusion properties of tissue which encapsulates subcutaneous implants. Polymeric Materials Science and Engineering, Proceedings of the Acs Division of Polymeric Materials Science and Engineering.
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Sharkawy, A. A., Klitzman, B., Truskey, G. A., & Reichert, W. M. (1996). Diffusion properties of capsular tissue. Transactions of the Annual Meeting of the Society for Biomaterials in Conjunction With the International Biomaterials Symposium.
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du Laney, T. V., Truskey, G. A., & Klitzman, B. (1996). Fibronectin enhances cell spreading and retention on ePTFE under shear in vitro. Transactions of the Annual Meeting of the Society for Biomaterials in Conjunction With the International Biomaterials Symposium.
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Conference Papers
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Bishawi, M., Kaplan, M., Chidyagwai, S., Cappiello, J., Cherry, A., MacLeod, D., … Randles, A. (2022). Patient- and Ventilator-Specific Modeling to Drive the Use and Development of 3D Printed Devices for Rapid Ventilator Splitting During the COVID-19 Pandemic. In Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 13352 LNCS, pp. 137–149). https://doi.org/10.1007/978-3-031-08757-8_13Full Text
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Zhang, X., & Truskey, G. A. (2020). A novel in situ monitoring system of 3D engineered muscle. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, Microtas 2017 (pp. 1037–1038).
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Oliver, C. E., Davis, B. N., Hong, J., Huffman, K. M., & Truskey, G. A. (2017). Tissue-Engineered Human Skeletal Muscle Model of Rheumatoid Arthritis. In Tissue Engineering Part A (Vol. 23, pp. S82–S82). Charlotte, NC: MARY ANN LIEBERT, INC.Link to Item
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Zhang, X., & Truskey, G. A. (2017). In Situ Monitoring of Engineering Muscle to Assess Myopathy. In Tissue Engineering Part A (Vol. 23, pp. S117–S117). Charlotte, NC: MARY ANN LIEBERT, INC.Link to Item
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Oliver, C. E., Davis, B. N., Hong, J., Huffman, K. M., & Truskey, G. A. (2017). Tissue-Engineered Human Skeletal Muscle Model of Rheumatoid Arthritis. In Arthritis & Rheumatology (Vol. 69). WILEY.Link to Item
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Fernandez, C. E., Povsic, T. J., & Truskey, G. A. (2016). Statin Responses within a Human Vascular Microphysiological System under Inflammatory Conditions. In Tissue Engineering Part A (Vol. 22, pp. S23–S23). San Diego, CA: MARY ANN LIEBERT, INC.Link to Item
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Christoforou, N., Ji, H., Atchison, L., Teo, J., Truskey, G., & Leong, K. W. (2015). Transdifferentiation of Human Endothelial Progenitors into Functional Smooth Muscle Cells Following Induction with the Transcriptional Co-Activator MYOCD for Tissue Engineering Applications. In Tissue Engineering Part A (Vol. 21, pp. S141–S142). Boston, MA: MARY ANN LIEBERT, INC.Link to Item
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Fernandez, C. E., Yen, R. W., Perez, S. L., Povsic, T. J., Reichert, W. M., & Truskey, G. A. (2015). Human Tissue Engineered Blood Vessels for in vitro Drug Testing. In Tissue Engineering Part A (Vol. 21, pp. S318–S318). Boston, MA: MARY ANN LIEBERT, INC.Link to Item
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Jung, Y., Ji, H., Chen, Z., Chan, H., Atchison, L., Klitzman, B., … Leong, K. W. (2015). Fabrication of Scaffold-free Tissue Engineered Blood Vessel using Nanopatterned Human Mesenchymal Stem Cell Sheet. In Tissue Engineering Part A (Vol. 21, pp. S271–S271). Boston, MA: MARY ANN LIEBERT, INC.Link to Item
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Madden, L., Jackman, C., Wang, J., Kraus, W., Truskey, G., & Bursac, N. (2015). Novel In Vitro Exercise Model of Engineered Human Skeletal Muscle. In Tissue Engineering Part A (Vol. 21, pp. S46–S46). Boston, MA: MARY ANN LIEBERT, INC.Link to Item
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Khismatullin, D. B., & Truskey, G. A. (2013). Viscoelastic Cell Adhesion Model (VECAM). In Biophysical Journal (Vol. 104, pp. 319a-320a). Elsevier BV. https://doi.org/10.1016/j.bpj.2012.11.1772Full Text
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Shaked, N. T., Satterwhite, L. L., Telen, M. J., Truskey, G. A., & Wax, A. (2012). Dynamic quantitative microscopy and nanoscopy of red blood cells in sickle cell disease. In Progress in Biomedical Optics and Imaging Proceedings of Spie (Vol. 8227). https://doi.org/10.1117/12.907659Full Text
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Truskey, G. A., & Irick, J. P. (2008). Effect of fatty acid exchange on leukocyte mechanical properties and adhesion to endothelium. In Biorheology (Vol. 45, pp. 32–33). IOS PRESS.Link to Item
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Khismatullin, D. B., & Truskey, G. A. (2006). Three-dimensional computational modeling of leukocyte rolling and adhesion. In 2006 Asme Joint U.S. European Fluids Engineering Summer Meeting, Fedsm 2006 (Vol. 2006).
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Khismatullin, D. B., & Truskey, G. A. (2006). Three-dimensional computational modeling of leukocyte rolling and adhesion. In Proceedings of Asme Fluids Engineering Division Summer Meeting 2006, Fedsm2006 (Vol. 2 FORUMS, pp. 633–638). https://doi.org/10.1115/fedsm2006-98555Full Text
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Pourtaheri, N., & Truskey, G. A. (2004). Real-time theoretical compartmental model of blood-brain barrier drug delivery. In Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference (Vol. 2006, pp. 790–796). https://doi.org/10.1109/iembs.2004.1403277Full Text
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Chan, B. P., Reichert, W. M., & Truskey, G. A. (2003). A customized DNA array reveals possible pathways for the production of streptavidin(SA)-biotin-induced nitric oxide. In Faseb Journal (Vol. 17, pp. A80–A80). SAN DIEGO, CALIFORNIA: FEDERATION AMER SOC EXP BIOL.Link to Item
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REICHERT, W. M., TRUSKEY, G. A., & WINAKUR, E. (1989). TOTAL INTERNAL-REFLECTION FLUORESCENCE VIDEO MICROSCOPY OF CELL-SURFACE CONTACTS. In Abstracts of Papers of the American Chemical Society (Vol. 198, pp. 177-ANYL). AMER CHEMICAL SOC.Link to Item
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NICOLAKIS, D. P., TRUSKEY, G. A., HABERMAN, A., & SWARTZ, R. W. (1988). METABOLIC STUDIES OF HYBRIDOMAS IN FED-BATCH BIOREACTOR. In Abstracts of Papers of the American Chemical Society (Vol. 196, pp. 1-MBTD). AMER CHEMICAL SOC.Link to Item
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- Teaching & Mentoring
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Recent Courses
- BME 394: Projects in Biomedical Engineering (GE) 2023
- BME 493: Projects in Biomedical Engineering (GE) 2023
- BME 494: Projects in Biomedical Engineering (GE) 2023
- BME 590: Special Topics in Biomedical Engineering 2023
- BME 791: Graduate Independent Study 2023
- BME 394: Projects in Biomedical Engineering (GE) 2022
- BME 493: Projects in Biomedical Engineering (GE) 2022
- BME 494: Projects in Biomedical Engineering (GE) 2022
- BME 590: Special Topics in Biomedical Engineering 2022
- BME 791: Graduate Independent Study 2022
- BME 792: Continuation of Graduate Independent Study 2022
- BME 394: Projects in Biomedical Engineering (GE) 2021
- BME 493: Projects in Biomedical Engineering (GE) 2021
- BME 494: Projects in Biomedical Engineering (GE) 2021
- BME 590: Special Topics in Biomedical Engineering 2021
- BME 791: Graduate Independent Study 2021
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