
Fourier-domain low-coherence interferometry for light-scattering spectroscopy.
We present a novel method for obtaining depth-resolved spectra for determining scatterer size through elastic-scattering properties. Depth resolution is achieved with a white-light source in a Michelson interferometer with the mixed signal and reference fields dispersed by a spectrograph. The spectrum is Fourier transformed to yield the axial spatial cross correlation between the signal and reference fields with near 1-microm depth resolution. Spectral information is obtained by windowing to yield the scattering amplitude as a function of wave number. The technique is demonstrated by determination of the size of polystyrene microspheres in a subsurface layer with subwavelength accuracy. Application of the technique to probing the size of cell nuclei in living epithelial tissues is discussed.
Duke Scholars
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Related Subject Headings
- Spectrum Analysis
- Scattering, Radiation
- Optics
- Models, Theoretical
- Light
- Interferometry
- Fourier Analysis
- 0906 Electrical and Electronic Engineering
- 0206 Quantum Physics
- 0205 Optical Physics
Citation

Published In
DOI
EISSN
ISSN
Publication Date
Volume
Issue
Start / End Page
Related Subject Headings
- Spectrum Analysis
- Scattering, Radiation
- Optics
- Models, Theoretical
- Light
- Interferometry
- Fourier Analysis
- 0906 Electrical and Electronic Engineering
- 0206 Quantum Physics
- 0205 Optical Physics