The dielectric constant of phospholipid bilayers and the permeability of membranes to ions.
Publication
, Journal Article
Dilger, JP; McLaughlin, SG; McIntosh, TJ; Simon, SA
Published in: Science
December 7, 1979
The Born charging equation predicts that the permeability of a phospholipid bilayer membrane to ions should depend markedly on the dielectric constant of the membrane. Increasing the dielectric constant of an artificial bilayer increases its permeability to perchlorate or thiocyanate by a factor of 1000, to a value comparable to that of mitochondrial membranes.
Duke Scholars
Published In
Science
DOI
ISSN
0036-8075
Publication Date
December 7, 1979
Volume
206
Issue
4423
Start / End Page
1196 / 1198
Location
United States
Related Subject Headings
- Thiocyanates
- Phosphatidylcholines
- Permeability
- Perchlorates
- Mitochondria
- Lipid Bilayers
- Hydrocarbons, Chlorinated
- General Science & Technology
- Electric Conductivity
- Chemistry, Physical
Citation
APA
Chicago
ICMJE
MLA
NLM
Dilger, J. P., McLaughlin, S. G., McIntosh, T. J., & Simon, S. A. (1979). The dielectric constant of phospholipid bilayers and the permeability of membranes to ions. Science, 206(4423), 1196–1198. https://doi.org/10.1126/science.228394
Dilger, J. P., S. G. McLaughlin, T. J. McIntosh, and S. A. Simon. “The dielectric constant of phospholipid bilayers and the permeability of membranes to ions.” Science 206, no. 4423 (December 7, 1979): 1196–98. https://doi.org/10.1126/science.228394.
Dilger JP, McLaughlin SG, McIntosh TJ, Simon SA. The dielectric constant of phospholipid bilayers and the permeability of membranes to ions. Science. 1979 Dec 7;206(4423):1196–8.
Dilger, J. P., et al. “The dielectric constant of phospholipid bilayers and the permeability of membranes to ions.” Science, vol. 206, no. 4423, Dec. 1979, pp. 1196–98. Pubmed, doi:10.1126/science.228394.
Dilger JP, McLaughlin SG, McIntosh TJ, Simon SA. The dielectric constant of phospholipid bilayers and the permeability of membranes to ions. Science. 1979 Dec 7;206(4423):1196–1198.
Published In
Science
DOI
ISSN
0036-8075
Publication Date
December 7, 1979
Volume
206
Issue
4423
Start / End Page
1196 / 1198
Location
United States
Related Subject Headings
- Thiocyanates
- Phosphatidylcholines
- Permeability
- Perchlorates
- Mitochondria
- Lipid Bilayers
- Hydrocarbons, Chlorinated
- General Science & Technology
- Electric Conductivity
- Chemistry, Physical