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Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories.

Publication ,  Journal Article
Bacanskas, LR; Whitaker, J; Di Giulio, RT
Published in: Marine environmental research
August 2004

A population of killifish (Fundulus heteroclitus) inhabiting a creosote-polluted inlet of the Elizabeth River demonstrates tolerance to the acute toxic effects exerted by contaminated sediments on reference site killifish. Previous data have suggested that upregulated antioxidant defenses contribute to short-term tolerance in killifish exposed to Elizabeth River sediments. This study investigated population differences in antioxidant defenses from wild caught Elizabeth River and reference population killifish in different seasons, and after being held in the laboratory. Parameters measured in the killifish were total glutathione concentrations (GSH(T)), activities of glutathione reductase (GR), glutathione peroxidase (GPx), and lipid peroxidation (LPO), all in adult hepatic tissues. The Elizabeth River population exhibited greater GSH(T), higher GPx activities, and increased LPO as compared to the reference population. Sex specific population differences were also observed in GSH(T) and GPx. Both populations displayed decreased GSH(T) and increased GR from early to late summer, as well as after being held in the laboratory. This study indicates that there are many factors that may contribute to differences in levels of antioxidant defenses in addition to exposure to contaminants, including reproductive status and environmental conditions.

Duke Scholars

Published In

Marine environmental research

DOI

EISSN

1879-0291

ISSN

0141-1136

Publication Date

August 2004

Volume

58

Issue

2-5

Start / End Page

597 / 601

Related Subject Headings

  • Virginia
  • Thiobarbituric Acid Reactive Substances
  • Sex Factors
  • Seasons
  • Rivers
  • Oxidative Stress
  • Marine Biology & Hydrobiology
  • Liver
  • Lipid Peroxidation
  • Glutathione Reductase
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Bacanskas, L. R., Whitaker, J., & Di Giulio, R. T. (2004). Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories. Marine Environmental Research, 58(2–5), 597–601. https://doi.org/10.1016/j.marenvres.2004.03.048
Bacanskas, Lisa R., Julia Whitaker, and Richard T. Di Giulio. “Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories.Marine Environmental Research 58, no. 2–5 (August 2004): 597–601. https://doi.org/10.1016/j.marenvres.2004.03.048.
Bacanskas LR, Whitaker J, Di Giulio RT. Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories. Marine environmental research. 2004 Aug;58(2–5):597–601.
Bacanskas, Lisa R., et al. “Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories.Marine Environmental Research, vol. 58, no. 2–5, Aug. 2004, pp. 597–601. Epmc, doi:10.1016/j.marenvres.2004.03.048.
Bacanskas LR, Whitaker J, Di Giulio RT. Oxidative stress in two populations of killifish (Fundulus heteroclitus) with differing contaminant exposure histories. Marine environmental research. 2004 Aug;58(2–5):597–601.
Journal cover image

Published In

Marine environmental research

DOI

EISSN

1879-0291

ISSN

0141-1136

Publication Date

August 2004

Volume

58

Issue

2-5

Start / End Page

597 / 601

Related Subject Headings

  • Virginia
  • Thiobarbituric Acid Reactive Substances
  • Sex Factors
  • Seasons
  • Rivers
  • Oxidative Stress
  • Marine Biology & Hydrobiology
  • Liver
  • Lipid Peroxidation
  • Glutathione Reductase