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Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study.

Publication ,  Journal Article
Poulton, R; Caspi, A; Moffitt, TE; Cannon, M; Murray, R; Harrington, H
Published in: Archives of general psychiatry
November 2000

Childhood risk factors for the development of adult schizophrenia have proved to have only modest and nonspecific effects, and most seem unrelated to the adult phenotype. We report the first direct examination of the longitudinal relationship between psychotic symptoms in childhood and adulthood.We analyzed prospective data from a birth cohort (N = 761), in which children were asked about delusional beliefs and hallucinatory experiences at age 11 years, and then followed up to age 26 years. Structured diagnostic interviews were employed at both ages and self-report of schizophreniform symptoms was augmented by other data sources at age 26 years.Self-reported psychotic symptoms at age 11 years predicted a very high risk of a schizophreniform diagnosis at age 26 years (odds ratio, 16.4; 95% confidence interval, 3.9-67.8). In terms of attributable risk, 42% of the age-26 schizophreniform cases in the cohort had reported 1 or more psychotic symptoms at age 11 years. Age-11 psychotic symptoms did not predict mania or depression at age 26 years, suggesting specificity of prediction to schizophreniform disorder. The link between child and adult psychotic symptoms was not simply the result of general childhood psychopathology.These findings provide the first evidence for continuity of psychotic symptoms from childhood to adulthood.

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Published In

Archives of general psychiatry

DOI

EISSN

1538-3636

ISSN

0003-990X

Publication Date

November 2000

Volume

57

Issue

11

Start / End Page

1053 / 1058

Related Subject Headings

  • Risk Factors
  • Psychotic Disorders
  • Psychiatry
  • Prospective Studies
  • Humans
  • Follow-Up Studies
  • Disease Progression
  • Cohort Studies
  • Child
  • Age Factors
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Poulton, R., Caspi, A., Moffitt, T. E., Cannon, M., Murray, R., & Harrington, H. (2000). Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study. Archives of General Psychiatry, 57(11), 1053–1058. https://doi.org/10.1001/archpsyc.57.11.1053
Poulton, R., A. Caspi, T. E. Moffitt, M. Cannon, R. Murray, and H. Harrington. “Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study.Archives of General Psychiatry 57, no. 11 (November 2000): 1053–58. https://doi.org/10.1001/archpsyc.57.11.1053.
Poulton R, Caspi A, Moffitt TE, Cannon M, Murray R, Harrington H. Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study. Archives of general psychiatry. 2000 Nov;57(11):1053–8.
Poulton, R., et al. “Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study.Archives of General Psychiatry, vol. 57, no. 11, Nov. 2000, pp. 1053–58. Epmc, doi:10.1001/archpsyc.57.11.1053.
Poulton R, Caspi A, Moffitt TE, Cannon M, Murray R, Harrington H. Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study. Archives of general psychiatry. 2000 Nov;57(11):1053–1058.

Published In

Archives of general psychiatry

DOI

EISSN

1538-3636

ISSN

0003-990X

Publication Date

November 2000

Volume

57

Issue

11

Start / End Page

1053 / 1058

Related Subject Headings

  • Risk Factors
  • Psychotic Disorders
  • Psychiatry
  • Prospective Studies
  • Humans
  • Follow-Up Studies
  • Disease Progression
  • Cohort Studies
  • Child
  • Age Factors