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Genetic linkage analysis of complex genetic traits by using affected sibling pairs.

Publication ,  Journal Article
Hauser, ER; Boehnke, M
Published in: Biometrics
December 1998

We provide an introduction to genetic linkage analysis. We discuss methods for the genetic analysis of common, complex disease such as diabetes, heart disease or hypertension. We describe the analysis of affected sibling pairs and discuss some of the challenges in applying these methods.

Duke Scholars

Published In

Biometrics

ISSN

0006-341X

Publication Date

December 1998

Volume

54

Issue

4

Start / End Page

1238 / 1246

Location

England

Related Subject Headings

  • Statistics & Probability
  • Pedigree
  • Nuclear Family
  • Male
  • Hypertension
  • Humans
  • Heart Diseases
  • Genetic Linkage
  • Female
  • Diabetes Mellitus
 

Citation

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Chicago
ICMJE
MLA
NLM
Hauser, E. R., & Boehnke, M. (1998). Genetic linkage analysis of complex genetic traits by using affected sibling pairs. Biometrics, 54(4), 1238–1246.
Hauser, E. R., and M. Boehnke. “Genetic linkage analysis of complex genetic traits by using affected sibling pairs.Biometrics 54, no. 4 (December 1998): 1238–46.
Hauser ER, Boehnke M. Genetic linkage analysis of complex genetic traits by using affected sibling pairs. Biometrics. 1998 Dec;54(4):1238–46.
Hauser, E. R., and M. Boehnke. “Genetic linkage analysis of complex genetic traits by using affected sibling pairs.Biometrics, vol. 54, no. 4, Dec. 1998, pp. 1238–46.
Hauser ER, Boehnke M. Genetic linkage analysis of complex genetic traits by using affected sibling pairs. Biometrics. 1998 Dec;54(4):1238–1246.
Journal cover image

Published In

Biometrics

ISSN

0006-341X

Publication Date

December 1998

Volume

54

Issue

4

Start / End Page

1238 / 1246

Location

England

Related Subject Headings

  • Statistics & Probability
  • Pedigree
  • Nuclear Family
  • Male
  • Hypertension
  • Humans
  • Heart Diseases
  • Genetic Linkage
  • Female
  • Diabetes Mellitus