Skip to main content

Therapeutic CD154 antibody for lupus: promise for the future?

Publication ,  Journal Article
Kelsoe, G
Published in: J Clin Invest
November 2003

Systemic lupus erythematosus (SLE) is a prototypical systemic autoimmune disease characterized by the production of pathogenic autoantibodies. A new study demonstrates that passive antibody specific for the TNF family member, CD154, ameliorates disease by reducing levels of self-reactive antibody in the serum. This study demonstrates a substantial potential for anti-CD154 antibody in the treatment of humoral autoimmunity.

Duke Scholars

Published In

J Clin Invest

DOI

ISSN

0021-9738

Publication Date

November 2003

Volume

112

Issue

10

Start / End Page

1480 / 1482

Location

United States

Related Subject Headings

  • Lupus Erythematosus, Systemic
  • Immunology
  • Immunization, Passive
  • Humans
  • CD40 Ligand
  • Autoimmunity
  • Autoantibodies
  • Antibodies, Monoclonal
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Kelsoe, G. (2003). Therapeutic CD154 antibody for lupus: promise for the future? J Clin Invest, 112(10), 1480–1482. https://doi.org/10.1172/JCI20371
Kelsoe, Garnett. “Therapeutic CD154 antibody for lupus: promise for the future?J Clin Invest 112, no. 10 (November 2003): 1480–82. https://doi.org/10.1172/JCI20371.
Kelsoe G. Therapeutic CD154 antibody for lupus: promise for the future? J Clin Invest. 2003 Nov;112(10):1480–2.
Kelsoe, Garnett. “Therapeutic CD154 antibody for lupus: promise for the future?J Clin Invest, vol. 112, no. 10, Nov. 2003, pp. 1480–82. Pubmed, doi:10.1172/JCI20371.
Kelsoe G. Therapeutic CD154 antibody for lupus: promise for the future? J Clin Invest. 2003 Nov;112(10):1480–1482.

Published In

J Clin Invest

DOI

ISSN

0021-9738

Publication Date

November 2003

Volume

112

Issue

10

Start / End Page

1480 / 1482

Location

United States

Related Subject Headings

  • Lupus Erythematosus, Systemic
  • Immunology
  • Immunization, Passive
  • Humans
  • CD40 Ligand
  • Autoimmunity
  • Autoantibodies
  • Antibodies, Monoclonal
  • 42 Health sciences
  • 32 Biomedical and clinical sciences