Progression of impairment in patients with vascular cognitive impairment without dementia.
Publication
, Journal Article
Wentzel, C; Rockwood, K; MacKnight, C; Hachinski, V; Hogan, DB; Feldman, H; Østbye, T; Wolfson, C; Gauthier, S; Verreault, R; McDowell, I
Published in: Neurology
August 28, 2001
Little is known about progression, short of dementia, in vascular cognitive impairment. In the Canadian Study of Health and Aging, 149 participants (79.3 +/- 6.7 years; 61% women) were found to have vascular cognitive impairment, no dementia (CIND). After 5 years, 77 participants (52%) had died and 58 (46%) had developed dementia. Women were at greater risk of dementia (OR 2.1, 1.0 to 4.5). Of 32 participants alive without dementia, cognition had deteriorated in seven and improved in four. Half of those with vascular CIND developed dementia within 5 years, suggesting a target for preventive interventions.
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Published In
Neurology
DOI
ISSN
0028-3878
Publication Date
August 28, 2001
Volume
57
Issue
4
Start / End Page
714 / 716
Location
United States
Related Subject Headings
- Odds Ratio
- Neuropsychological Tests
- Neurology & Neurosurgery
- Male
- Logistic Models
- Humans
- Female
- Disease Progression
- Dementia, Vascular
- Confidence Intervals
Citation
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Chicago
ICMJE
MLA
NLM
Wentzel, C., Rockwood, K., MacKnight, C., Hachinski, V., Hogan, D. B., Feldman, H., … McDowell, I. (2001). Progression of impairment in patients with vascular cognitive impairment without dementia. Neurology, 57(4), 714–716. https://doi.org/10.1212/wnl.57.4.714
Wentzel, C., K. Rockwood, C. MacKnight, V. Hachinski, D. B. Hogan, H. Feldman, T. Østbye, et al. “Progression of impairment in patients with vascular cognitive impairment without dementia.” Neurology 57, no. 4 (August 28, 2001): 714–16. https://doi.org/10.1212/wnl.57.4.714.
Wentzel C, Rockwood K, MacKnight C, Hachinski V, Hogan DB, Feldman H, et al. Progression of impairment in patients with vascular cognitive impairment without dementia. Neurology. 2001 Aug 28;57(4):714–6.
Wentzel, C., et al. “Progression of impairment in patients with vascular cognitive impairment without dementia.” Neurology, vol. 57, no. 4, Aug. 2001, pp. 714–16. Pubmed, doi:10.1212/wnl.57.4.714.
Wentzel C, Rockwood K, MacKnight C, Hachinski V, Hogan DB, Feldman H, Østbye T, Wolfson C, Gauthier S, Verreault R, McDowell I. Progression of impairment in patients with vascular cognitive impairment without dementia. Neurology. 2001 Aug 28;57(4):714–716.
Published In
Neurology
DOI
ISSN
0028-3878
Publication Date
August 28, 2001
Volume
57
Issue
4
Start / End Page
714 / 716
Location
United States
Related Subject Headings
- Odds Ratio
- Neuropsychological Tests
- Neurology & Neurosurgery
- Male
- Logistic Models
- Humans
- Female
- Disease Progression
- Dementia, Vascular
- Confidence Intervals