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Symptomatic remission in patients with bipolar mania: results from a double-blind, placebo-controlled trial of risperidone monotherapy.

Publication ,  Journal Article
Gopal, S; Steffens, DC; Kramer, ML; Olsen, MK
Published in: J Clin Psychiatry
August 2005

BACKGROUND: The purpose of this analysis was to assess rates of symptomatic remission in patients with bipolar mania receiving risperidone in a double-blind, parallel-group, multicenter, placebo-controlled trial conducted in India. METHOD: Two hundred ninety-one adult patients who met DSM-IV criteria for bipolar I disorder manic or mixed episode were randomly assigned to flexible doses of risperidone (1-6 mg/day, N = 146) or placebo (N = 145) for up to 3 weeks. An entry Young Mania Rating Scale (YMRS) score of >or= 20 was required at trial screening and baseline. Remission was defined as achieving and maintaining a YMRS score

Duke Scholars

Published In

J Clin Psychiatry

DOI

ISSN

0160-6689

Publication Date

August 2005

Volume

66

Issue

8

Start / End Page

1016 / 1020

Location

United States

Related Subject Headings

  • Survival Analysis
  • Severity of Illness Index
  • Risperidone
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Placebos
  • Male
  • Logistic Models
  • Humans
  • Female
 

Citation

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Gopal, S., Steffens, D. C., Kramer, M. L., & Olsen, M. K. (2005). Symptomatic remission in patients with bipolar mania: results from a double-blind, placebo-controlled trial of risperidone monotherapy. J Clin Psychiatry, 66(8), 1016–1020. https://doi.org/10.4088/jcp.v66n0809
Gopal, Srihari, David C. Steffens, Michelle L. Kramer, and Maren K. Olsen. “Symptomatic remission in patients with bipolar mania: results from a double-blind, placebo-controlled trial of risperidone monotherapy.J Clin Psychiatry 66, no. 8 (August 2005): 1016–20. https://doi.org/10.4088/jcp.v66n0809.
Gopal, Srihari, et al. “Symptomatic remission in patients with bipolar mania: results from a double-blind, placebo-controlled trial of risperidone monotherapy.J Clin Psychiatry, vol. 66, no. 8, Aug. 2005, pp. 1016–20. Pubmed, doi:10.4088/jcp.v66n0809.
Gopal S, Steffens DC, Kramer ML, Olsen MK. Symptomatic remission in patients with bipolar mania: results from a double-blind, placebo-controlled trial of risperidone monotherapy. J Clin Psychiatry. 2005 Aug;66(8):1016–1020.

Published In

J Clin Psychiatry

DOI

ISSN

0160-6689

Publication Date

August 2005

Volume

66

Issue

8

Start / End Page

1016 / 1020

Location

United States

Related Subject Headings

  • Survival Analysis
  • Severity of Illness Index
  • Risperidone
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Placebos
  • Male
  • Logistic Models
  • Humans
  • Female