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Symmetry aortic connector devices and acute renal injury: a comparison of renal dysfunction after three different aortocoronary bypass surgery techniques.

Publication ,  Journal Article
Fischer, SSF; Phillips-Bute, B; Swaminathan, M; Milano, C; Stafford-Smith, M
Published in: Anesth Analg
January 2006

Although the pathogenesis of acute renal injury after cardiac surgery is multifactorial, atherosclerosis of the ascending aorta and embolic burden are strong independent predictors. Use of the Symmetry aortic connector device (ACD) for proximal anastomosis of coronary grafts may reduce ascending aortic atheroembolism. Therefore, we tested the hypothesis that off-pump coronary artery bypass (OPCAB) surgery performed using an ACD is associated with less postoperative renal dysfunction compared with conventional OPCAB or on-pump coronary artery bypass graft (CABG) surgery. Three-thousand-three-hundred consecutive patients undergoing non-emergent aortocoronary bypass surgery were retrospectively divided into three groups by surgical procedure; Group A: OPCAB with ACD (n = 124), Group B: standard OPCAB (n = 313), Group C: on-pump CABG (n = 2863). Postoperative peak fractional change in creatinine compared with baseline was used as a measure of renal outcome. Multivariable analysis did not identify ACD use as an independent predictor of postoperative peak fractional change in creatinine (P = 0.71), although the relationships of several known renal risk factors with postoperative peak fractional change in creatinine were confirmed. We could not find evidence that OPCAB surgery using ACDs reduces acute renal injury compared with standard OPCAB or CABG surgery.

Duke Scholars

Published In

Anesth Analg

DOI

EISSN

1526-7598

Publication Date

January 2006

Volume

102

Issue

1

Start / End Page

25 / 31

Location

United States

Related Subject Headings

  • Surgical Instruments
  • Risk Factors
  • Retrospective Studies
  • Prospective Studies
  • Multivariate Analysis
  • Middle Aged
  • Male
  • Humans
  • Female
  • Coronary Artery Bypass
 

Citation

APA
Chicago
ICMJE
MLA
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Fischer, S. S. F., Phillips-Bute, B., Swaminathan, M., Milano, C., & Stafford-Smith, M. (2006). Symmetry aortic connector devices and acute renal injury: a comparison of renal dysfunction after three different aortocoronary bypass surgery techniques. Anesth Analg, 102(1), 25–31. https://doi.org/10.1213/01.ane.0000189054.17725.73
Fischer, Stephanie S. F., Barbara Phillips-Bute, Madhav Swaminathan, Carmelo Milano, and Mark Stafford-Smith. “Symmetry aortic connector devices and acute renal injury: a comparison of renal dysfunction after three different aortocoronary bypass surgery techniques.Anesth Analg 102, no. 1 (January 2006): 25–31. https://doi.org/10.1213/01.ane.0000189054.17725.73.
Fischer SSF, Phillips-Bute B, Swaminathan M, Milano C, Stafford-Smith M. Symmetry aortic connector devices and acute renal injury: a comparison of renal dysfunction after three different aortocoronary bypass surgery techniques. Anesth Analg. 2006 Jan;102(1):25–31.
Fischer, Stephanie S. F., et al. “Symmetry aortic connector devices and acute renal injury: a comparison of renal dysfunction after three different aortocoronary bypass surgery techniques.Anesth Analg, vol. 102, no. 1, Jan. 2006, pp. 25–31. Pubmed, doi:10.1213/01.ane.0000189054.17725.73.
Fischer SSF, Phillips-Bute B, Swaminathan M, Milano C, Stafford-Smith M. Symmetry aortic connector devices and acute renal injury: a comparison of renal dysfunction after three different aortocoronary bypass surgery techniques. Anesth Analg. 2006 Jan;102(1):25–31.

Published In

Anesth Analg

DOI

EISSN

1526-7598

Publication Date

January 2006

Volume

102

Issue

1

Start / End Page

25 / 31

Location

United States

Related Subject Headings

  • Surgical Instruments
  • Risk Factors
  • Retrospective Studies
  • Prospective Studies
  • Multivariate Analysis
  • Middle Aged
  • Male
  • Humans
  • Female
  • Coronary Artery Bypass