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Immunohistochemistry of the glial fibrillary acidic protein: basic and applied considerations.

Publication ,  Journal Article
McLendon, RE; Bigner, DD
Published in: Brain Pathol
July 1994

The immunohistochemical localization of glial fibrillary acidic protein has proven its utility in the histologic identification of benign astrocytes and neoplastic cells of glial lineage in the central nervous system. Its application in the developing nervous system has contributed significantly to following the histogenesis of neural tissue. Its identification in various forms of injury and neoplasia has helped in discovering the function of astrocytes in these processes. In diagnostic neuropathology, its greatest contribution has been in the elucidation of the cellular constituencies of neoplasms previously considered of enigmatic origin.

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Published In

Brain Pathol

DOI

ISSN

1015-6305

Publication Date

July 1994

Volume

4

Issue

3

Start / End Page

221 / 228

Location

Switzerland

Related Subject Headings

  • Predictive Value of Tests
  • Oligodendroglioma
  • Neurology & Neurosurgery
  • Immunohistochemistry
  • Humans
  • Glioblastoma
  • Glial Fibrillary Acidic Protein
  • Central Nervous System Neoplasms
  • Brain Neoplasms
  • Brain
 

Citation

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McLendon, R. E., & Bigner, D. D. (1994). Immunohistochemistry of the glial fibrillary acidic protein: basic and applied considerations. Brain Pathol, 4(3), 221–228. https://doi.org/10.1111/j.1750-3639.1994.tb00837.x
McLendon, R. E., and D. D. Bigner. “Immunohistochemistry of the glial fibrillary acidic protein: basic and applied considerations.Brain Pathol 4, no. 3 (July 1994): 221–28. https://doi.org/10.1111/j.1750-3639.1994.tb00837.x.
McLendon, R. E., and D. D. Bigner. “Immunohistochemistry of the glial fibrillary acidic protein: basic and applied considerations.Brain Pathol, vol. 4, no. 3, July 1994, pp. 221–28. Pubmed, doi:10.1111/j.1750-3639.1994.tb00837.x.
McLendon RE, Bigner DD. Immunohistochemistry of the glial fibrillary acidic protein: basic and applied considerations. Brain Pathol. 1994 Jul;4(3):221–228.
Journal cover image

Published In

Brain Pathol

DOI

ISSN

1015-6305

Publication Date

July 1994

Volume

4

Issue

3

Start / End Page

221 / 228

Location

Switzerland

Related Subject Headings

  • Predictive Value of Tests
  • Oligodendroglioma
  • Neurology & Neurosurgery
  • Immunohistochemistry
  • Humans
  • Glioblastoma
  • Glial Fibrillary Acidic Protein
  • Central Nervous System Neoplasms
  • Brain Neoplasms
  • Brain