Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent ST-segment elevation: effect of inhibition of platelet glycoprotein IIb/IIIa with eptifibatide. The PURSUIT trial investigators.
Publication
, Journal Article
Hasdai, D; Holmes, DR; Criger, DA; Topol, EJ; Califf, RM; Wilcox, RG; Paolasso, E; Simoons, M; Deckers, J; Harrington, RA
Published in: Am Heart J
March 2000
BACKGROUND: Studies have shown that cigarette smokers constitute a substantial proportion of patients with acute coronary syndromes (ACS) and have platelet-rich coronary thrombi. We characterized the influence of smoking status on outcome of patients with ACS without persistent ST-segment elevation and tested the hypothesis that selective inhibition of the platelet glycoprotein IIb/IIIa receptor with eptifibatide would improve outcomes among cigarette smokers. METHODS: The study population included patients enrolled in the PURSUIT trial (Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy) with known smoking status presenting with ischemic chest pain
Duke Scholars
Published In
Am Heart J
DOI
ISSN
0002-8703
Publication Date
March 2000
Volume
139
Issue
3
Start / End Page
454 / 460
Location
United States
Related Subject Headings
- Treatment Outcome
- Smoking
- Platelet Glycoprotein GPIIb-IIIa Complex
- Platelet Aggregation Inhibitors
- Peptides
- Myocardial Infarction
- Middle Aged
- Male
- Humans
- Female
Citation
APA
Chicago
ICMJE
MLA
NLM
Hasdai, D., Holmes, D. R., Criger, D. A., Topol, E. J., Califf, R. M., Wilcox, R. G., … Harrington, R. A. (2000). Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent ST-segment elevation: effect of inhibition of platelet glycoprotein IIb/IIIa with eptifibatide. The PURSUIT trial investigators. Am Heart J, 139(3), 454–460. https://doi.org/10.1016/s0002-8703(00)90089-9
Hasdai, D., D. R. Holmes, D. A. Criger, E. J. Topol, R. M. Califf, R. G. Wilcox, E. Paolasso, M. Simoons, J. Deckers, and R. A. Harrington. “Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent ST-segment elevation: effect of inhibition of platelet glycoprotein IIb/IIIa with eptifibatide. The PURSUIT trial investigators.” Am Heart J 139, no. 3 (March 2000): 454–60. https://doi.org/10.1016/s0002-8703(00)90089-9.
Hasdai D, Holmes DR, Criger DA, Topol EJ, Califf RM, Wilcox RG, et al. Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent ST-segment elevation: effect of inhibition of platelet glycoprotein IIb/IIIa with eptifibatide. The PURSUIT trial investigators. Am Heart J. 2000 Mar;139(3):454–60.
Hasdai, D., et al. “Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent ST-segment elevation: effect of inhibition of platelet glycoprotein IIb/IIIa with eptifibatide. The PURSUIT trial investigators.” Am Heart J, vol. 139, no. 3, Mar. 2000, pp. 454–60. Pubmed, doi:10.1016/s0002-8703(00)90089-9.
Hasdai D, Holmes DR, Criger DA, Topol EJ, Califf RM, Wilcox RG, Paolasso E, Simoons M, Deckers J, Harrington RA. Cigarette smoking status and outcome among patients with acute coronary syndromes without persistent ST-segment elevation: effect of inhibition of platelet glycoprotein IIb/IIIa with eptifibatide. The PURSUIT trial investigators. Am Heart J. 2000 Mar;139(3):454–460.
Published In
Am Heart J
DOI
ISSN
0002-8703
Publication Date
March 2000
Volume
139
Issue
3
Start / End Page
454 / 460
Location
United States
Related Subject Headings
- Treatment Outcome
- Smoking
- Platelet Glycoprotein GPIIb-IIIa Complex
- Platelet Aggregation Inhibitors
- Peptides
- Myocardial Infarction
- Middle Aged
- Male
- Humans
- Female