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Salicylic acid inhibits pathogen growth in plants through repression of the auxin signaling pathway.

Publication ,  Journal Article
Wang, D; Pajerowska-Mukhtar, K; Culler, AH; Dong, X
Published in: Current biology : CB
October 2007

The phytohormone auxin regulates almost every aspect of plant development. At the molecular level, auxin induces gene expression through direct physical interaction with the TIR1-like F box proteins, which in turn remove the Aux/IAA family of transcriptional repressors [1-4]. A growing body of evidence indicates that many plant pathogens can either produce auxin themselves or manipulate host auxin biosynthesis to interfere with the host's normal developmental processes [5-11]. In response, plants probably evolved mechanisms to repress auxin signaling during infection as a defense strategy. Plants overaccumulating the defense signal molecule salicylic acid (SA) frequently display morphological phenotypes that are reminiscent of auxin-deficient or auxin-insensitive mutants, indicating that SA might interfere with auxin responses. By using the Affymetrix ATH1 GeneChip for Arabidopsis thaliana, we performed a comprehensive study of the effects of SA on auxin signaling [12]. We found that SA causes global repression of auxin-related genes, including the TIR1 receptor gene, resulting in stabilization of the Aux/IAA repressor proteins and inhibition of auxin responses. We demonstrate that this inhibitory effect on auxin signaling is a part of the SA-mediated disease-resistance mechanism.

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Published In

Current biology : CB

DOI

EISSN

1879-0445

ISSN

0960-9822

Publication Date

October 2007

Volume

17

Issue

20

Start / End Page

1784 / 1790

Related Subject Headings

  • Thiadiazoles
  • Signal Transduction
  • Salicylic Acid
  • Plants, Genetically Modified
  • Plant Growth Regulators
  • Plant Diseases
  • Oligonucleotide Array Sequence Analysis
  • Mutation
  • Indoleacetic Acids
  • Genes, Plant
 

Citation

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Wang, D., Pajerowska-Mukhtar, K., Culler, A. H., & Dong, X. (2007). Salicylic acid inhibits pathogen growth in plants through repression of the auxin signaling pathway. Current Biology : CB, 17(20), 1784–1790. https://doi.org/10.1016/j.cub.2007.09.025
Wang, Dong, Karolina Pajerowska-Mukhtar, Angela Hendrickson Culler, and Xinnian Dong. “Salicylic acid inhibits pathogen growth in plants through repression of the auxin signaling pathway.Current Biology : CB 17, no. 20 (October 2007): 1784–90. https://doi.org/10.1016/j.cub.2007.09.025.
Wang D, Pajerowska-Mukhtar K, Culler AH, Dong X. Salicylic acid inhibits pathogen growth in plants through repression of the auxin signaling pathway. Current biology : CB. 2007 Oct;17(20):1784–90.
Wang, Dong, et al. “Salicylic acid inhibits pathogen growth in plants through repression of the auxin signaling pathway.Current Biology : CB, vol. 17, no. 20, Oct. 2007, pp. 1784–90. Epmc, doi:10.1016/j.cub.2007.09.025.
Wang D, Pajerowska-Mukhtar K, Culler AH, Dong X. Salicylic acid inhibits pathogen growth in plants through repression of the auxin signaling pathway. Current biology : CB. 2007 Oct;17(20):1784–1790.
Journal cover image

Published In

Current biology : CB

DOI

EISSN

1879-0445

ISSN

0960-9822

Publication Date

October 2007

Volume

17

Issue

20

Start / End Page

1784 / 1790

Related Subject Headings

  • Thiadiazoles
  • Signal Transduction
  • Salicylic Acid
  • Plants, Genetically Modified
  • Plant Growth Regulators
  • Plant Diseases
  • Oligonucleotide Array Sequence Analysis
  • Mutation
  • Indoleacetic Acids
  • Genes, Plant