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Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity.

Publication ,  Journal Article
Bedlack, RS; Simel, DL; Bosworth, H; Samsa, G; Tucker-Lipscomb, B; Sanders, DB
Published in: Neurology
June 14, 2005

We prospectively tested the quantitative myasthenia gravis score (QMG) for responsiveness and longitudinal construct validity in 53 patients with myasthenia gravis. Index of responsiveness was high. Longitudinal construct validity was confirmed by the correlation between changes in QMG and manual muscle testing and by a difference in QMG changes across patients that were clinically unchanged, improved, or worse between two visits. Our results support QMG use for assessing clinical change in trials.

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Published In

Neurology

DOI

EISSN

1526-632X

Publication Date

June 14, 2005

Volume

64

Issue

11

Start / End Page

1968 / 1970

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Reproducibility of Results
  • Receptors, Nicotinic
  • Receptors, Cholinergic
  • Receptor Protein-Tyrosine Kinases
  • Prospective Studies
  • Prognosis
  • Predictive Value of Tests
  • Neurology & Neurosurgery
  • Myasthenia Gravis
 

Citation

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Bedlack, R. S., Simel, D. L., Bosworth, H., Samsa, G., Tucker-Lipscomb, B., & Sanders, D. B. (2005). Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity. Neurology, 64(11), 1968–1970. https://doi.org/10.1212/01.WNL.0000163988.28892.79
Bedlack, R. S., D. L. Simel, H. Bosworth, G. Samsa, B. Tucker-Lipscomb, and D. B. Sanders. “Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity.Neurology 64, no. 11 (June 14, 2005): 1968–70. https://doi.org/10.1212/01.WNL.0000163988.28892.79.
Bedlack RS, Simel DL, Bosworth H, Samsa G, Tucker-Lipscomb B, Sanders DB. Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity. Neurology. 2005 Jun 14;64(11):1968–70.
Bedlack, R. S., et al. “Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity.Neurology, vol. 64, no. 11, June 2005, pp. 1968–70. Pubmed, doi:10.1212/01.WNL.0000163988.28892.79.
Bedlack RS, Simel DL, Bosworth H, Samsa G, Tucker-Lipscomb B, Sanders DB. Quantitative myasthenia gravis score: assessment of responsiveness and longitudinal validity. Neurology. 2005 Jun 14;64(11):1968–1970.

Published In

Neurology

DOI

EISSN

1526-632X

Publication Date

June 14, 2005

Volume

64

Issue

11

Start / End Page

1968 / 1970

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Reproducibility of Results
  • Receptors, Nicotinic
  • Receptors, Cholinergic
  • Receptor Protein-Tyrosine Kinases
  • Prospective Studies
  • Prognosis
  • Predictive Value of Tests
  • Neurology & Neurosurgery
  • Myasthenia Gravis