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PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice.

Publication ,  Journal Article
Sun, LV; Jin, K; Liu, Y; Yang, W; Xie, X; Ye, L; Wang, L; Zhu, L; Ding, S; Su, Y; Zhou, J; Han, M; Zhuang, Y; Xu, T; Wu, X; Gu, N; Zhong, Y
Published in: Nucleic Acids Res
January 2008

DNA transposon piggyBac (PB) is a newly established mutagen for large-scale mutagenesis in mice. We have designed and implemented an integrated database system called PBmice (PB Mutagenesis Information CEnter) for storing, retrieving and displaying the information derived from PB insertions (INSERTs) in the mouse genome. This system is centered on INSERTs with information including their genomic locations and flanking genomic sequences, the expression levels of the hit genes, and the expression patterns of the trapped genes if a trapping vector was used. It also archives mouse phenotyping data linked to INSERTs, and allows users to conduct quick and advanced searches for genotypic and phenotypic information relevant to a particular or a set of INSERT(s). Sequence-based information can be cross-referenced with other genomic databases such as Ensembl, BLAST and GBrowse tools used in PBmice offer enhanced search and display for additional information relevant to INSERTs. The total number and genomic distribution of PB INSERTs, as well as the availability of each PB insertional LINE can also be viewed with user-friendly interfaces. PBmice is freely available at http://www.idmshanghai.cn/PBmice or http://www.scbit.org/PBmice/.

Duke Scholars

Published In

Nucleic Acids Res

DOI

EISSN

1362-4962

Publication Date

January 2008

Volume

36

Issue

Database issue

Start / End Page

D729 / D734

Location

England

Related Subject Headings

  • User-Computer Interface
  • Systems Integration
  • Phenotype
  • Mutagenesis, Insertional
  • Mice
  • Internet
  • Genomics
  • Gene Expression
  • Developmental Biology
  • Databases, Genetic
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Sun, L. V., Jin, K., Liu, Y., Yang, W., Xie, X., Ye, L., … Zhong, Y. (2008). PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. Nucleic Acids Res, 36(Database issue), D729–D734. https://doi.org/10.1093/nar/gkm790
Sun, Ling V., Ke Jin, Yiming Liu, Wenwei Yang, Xing Xie, Lin Ye, Li Wang, et al. “PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice.Nucleic Acids Res 36, no. Database issue (January 2008): D729–34. https://doi.org/10.1093/nar/gkm790.
Sun LV, Jin K, Liu Y, Yang W, Xie X, Ye L, et al. PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. Nucleic Acids Res. 2008 Jan;36(Database issue):D729–34.
Sun, Ling V., et al. “PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice.Nucleic Acids Res, vol. 36, no. Database issue, Jan. 2008, pp. D729–34. Pubmed, doi:10.1093/nar/gkm790.
Sun LV, Jin K, Liu Y, Yang W, Xie X, Ye L, Wang L, Zhu L, Ding S, Su Y, Zhou J, Han M, Zhuang Y, Xu T, Wu X, Gu N, Zhong Y. PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice. Nucleic Acids Res. 2008 Jan;36(Database issue):D729–D734.
Journal cover image

Published In

Nucleic Acids Res

DOI

EISSN

1362-4962

Publication Date

January 2008

Volume

36

Issue

Database issue

Start / End Page

D729 / D734

Location

England

Related Subject Headings

  • User-Computer Interface
  • Systems Integration
  • Phenotype
  • Mutagenesis, Insertional
  • Mice
  • Internet
  • Genomics
  • Gene Expression
  • Developmental Biology
  • Databases, Genetic