Selective inhibition of the duck hepatitis B virus by a new class of tetraazamacrocycles.
Publication
, Journal Article
Hantz, O; Borel, C; Trabaud, C; Zoulim, F; Dessolin, J; Camplo, M; Vlieghe, P; Bouygues, M; Trepo, C; Kraus, JL
Published in: Antimicrob Agents Chemother
November 1997
The antiviral activity of a new class of N,N,N',N",NA'''-pentakis (omega-aminoalkyl) tetraazamacrocycles was evaluated in primary duck hepatocyte cultures infected with the duck hepatitis B virus (DHBV). Three of the four tested compounds were able to selectively inhibit DHBV replication by acting at an early step of the hepadnavirus infection but were associated with significant toxicity.
Duke Scholars
Published In
Antimicrob Agents Chemother
DOI
ISSN
0066-4804
Publication Date
November 1997
Volume
41
Issue
11
Start / End Page
2579 / 2581
Location
United States
Related Subject Headings
- Structure-Activity Relationship
- Microbiology
- Microbial Sensitivity Tests
- Liver
- Heterocyclic Compounds
- Hepatitis B Virus, Duck
- DNA, Viral
- Cells, Cultured
- Cell Survival
- Aza Compounds
Citation
APA
Chicago
ICMJE
MLA
NLM
Hantz, O., Borel, C., Trabaud, C., Zoulim, F., Dessolin, J., Camplo, M., … Kraus, J. L. (1997). Selective inhibition of the duck hepatitis B virus by a new class of tetraazamacrocycles. Antimicrob Agents Chemother, 41(11), 2579–2581. https://doi.org/10.1128/AAC.41.11.2579
Hantz, O., C. Borel, C. Trabaud, F. Zoulim, J. Dessolin, M. Camplo, P. Vlieghe, M. Bouygues, C. Trepo, and J. L. Kraus. “Selective inhibition of the duck hepatitis B virus by a new class of tetraazamacrocycles.” Antimicrob Agents Chemother 41, no. 11 (November 1997): 2579–81. https://doi.org/10.1128/AAC.41.11.2579.
Hantz O, Borel C, Trabaud C, Zoulim F, Dessolin J, Camplo M, et al. Selective inhibition of the duck hepatitis B virus by a new class of tetraazamacrocycles. Antimicrob Agents Chemother. 1997 Nov;41(11):2579–81.
Hantz, O., et al. “Selective inhibition of the duck hepatitis B virus by a new class of tetraazamacrocycles.” Antimicrob Agents Chemother, vol. 41, no. 11, Nov. 1997, pp. 2579–81. Pubmed, doi:10.1128/AAC.41.11.2579.
Hantz O, Borel C, Trabaud C, Zoulim F, Dessolin J, Camplo M, Vlieghe P, Bouygues M, Trepo C, Kraus JL. Selective inhibition of the duck hepatitis B virus by a new class of tetraazamacrocycles. Antimicrob Agents Chemother. 1997 Nov;41(11):2579–2581.
Published In
Antimicrob Agents Chemother
DOI
ISSN
0066-4804
Publication Date
November 1997
Volume
41
Issue
11
Start / End Page
2579 / 2581
Location
United States
Related Subject Headings
- Structure-Activity Relationship
- Microbiology
- Microbial Sensitivity Tests
- Liver
- Heterocyclic Compounds
- Hepatitis B Virus, Duck
- DNA, Viral
- Cells, Cultured
- Cell Survival
- Aza Compounds