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Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation.

Publication ,  Journal Article
Lyman, GH; Preisler, HD; Papahadjopoulos, D
Published in: Nature
July 29, 1976

DMSO and other cryoprotective agents produce a pronounced increase on the phase transition temperature of phospholipid membranes, indicating an increased stability. The effects of DMSO and other cryoprotective agents, divalent cations, and local anaesthetics on the transition temperature of phospholipid membranes seem to correlate with their effects on the differentiation of Friend leukaemic cells in vitro. These studies suggest that the induction of differentiation by cryoprotective agents may be the result of the interaction of these agents with cell membranes.

Duke Scholars

Published In

Nature

DOI

ISSN

0028-0836

Publication Date

July 29, 1976

Volume

262

Issue

5567

Start / End Page

361 / 363

Location

England

Related Subject Headings

  • Temperature
  • Phospholipids
  • Phosphatidylglycerols
  • Methylurea Compounds
  • Leukemia, Experimental
  • General Science & Technology
  • Dimethyl Sulfoxide
  • Cryoprotective Agents
  • Chemistry, Physical
  • Chemical Phenomena
 

Citation

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ICMJE
MLA
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Lyman, G. H., Preisler, H. D., & Papahadjopoulos, D. (1976). Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation. Nature, 262(5567), 361–363. https://doi.org/10.1038/262360a0
Lyman, G. H., H. D. Preisler, and D. Papahadjopoulos. “Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation.Nature 262, no. 5567 (July 29, 1976): 361–63. https://doi.org/10.1038/262360a0.
Lyman GH, Preisler HD, Papahadjopoulos D. Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation. Nature. 1976 Jul 29;262(5567):361–3.
Lyman, G. H., et al. “Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation.Nature, vol. 262, no. 5567, July 1976, pp. 361–63. Pubmed, doi:10.1038/262360a0.
Lyman GH, Preisler HD, Papahadjopoulos D. Membrane action of DMSO and other chemical inducers of Friend leukaemic cell differentiation. Nature. 1976 Jul 29;262(5567):361–363.
Journal cover image

Published In

Nature

DOI

ISSN

0028-0836

Publication Date

July 29, 1976

Volume

262

Issue

5567

Start / End Page

361 / 363

Location

England

Related Subject Headings

  • Temperature
  • Phospholipids
  • Phosphatidylglycerols
  • Methylurea Compounds
  • Leukemia, Experimental
  • General Science & Technology
  • Dimethyl Sulfoxide
  • Cryoprotective Agents
  • Chemistry, Physical
  • Chemical Phenomena