Skip to main content
construction release_alert
Scholars@Duke will be undergoing maintenance April 11-15. Some features may be unavailable during this time.
cancel
Journal cover image

Prognostic significance of the number of lymph nodes examined in patients with lymph node-negative breast carcinoma.

Publication ,  Journal Article
Moorman, PG; Hamza, A; Marks, JR; Olson, JA
Published in: Cancer
June 15, 2001

BACKGROUND: A recent report suggested that the number of lymph nodes examined was a strong predictor of survival in patients with lymph node-negative breast carcinoma. Among women who had >or= 20 lymph nodes examined, the risk of dying from breast carcinoma within 5 years was increased nearly 4-fold compared with women who had fewer lymph nodes examined. Because these findings were based on a relatively small cohort of patients, corroborative studies with larger patient populations were needed. METHODS: The authors studied the relation between the number of lymph nodes examined and breast carcinoma survival among 911 women with lymph node-negative breast carcinoma with a median length of follow-up of 84 months. The association between other prognostic indicators and survival and the number of lymph nodes examined also was investigated. RESULTS: The number of lymph nodes examined was not found to be associated with either 5-year or long-term survival. The proportion of women dying from breast carcinoma was the same (8%) in both groups (those patients with >or= 20 lymph nodes examined vs. those in whom < 20 lymph nodes were examined) and the hazard ratio was 0.98 (95% confidence interval, 0.58-1.64). CONCLUSIONS: In this larger study population, the authors failed to confirm the findings of an earlier investigation in which having a larger number of lymph nodes examined was associated with poorer survival. This finding suggests that it is unlikely the number of lymph nodes examined is an important prognostic indicator in patients with lymph node-negative breast carcinoma.

Duke Scholars

Published In

Cancer

ISSN

0008-543X

Publication Date

June 15, 2001

Volume

91

Issue

12

Start / End Page

2258 / 2262

Location

United States

Related Subject Headings

  • Prognosis
  • Oncology & Carcinogenesis
  • Middle Aged
  • Lymph Nodes
  • Humans
  • Follow-Up Studies
  • Female
  • Breast Neoplasms
  • Aged, 80 and over
  • Aged
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Moorman, P. G., Hamza, A., Marks, J. R., & Olson, J. A. (2001). Prognostic significance of the number of lymph nodes examined in patients with lymph node-negative breast carcinoma. Cancer, 91(12), 2258–2262.
Moorman, P. G., A. Hamza, J. R. Marks, and J. A. Olson. “Prognostic significance of the number of lymph nodes examined in patients with lymph node-negative breast carcinoma.Cancer 91, no. 12 (June 15, 2001): 2258–62.
Moorman PG, Hamza A, Marks JR, Olson JA. Prognostic significance of the number of lymph nodes examined in patients with lymph node-negative breast carcinoma. Cancer. 2001 Jun 15;91(12):2258–62.
Moorman, P. G., et al. “Prognostic significance of the number of lymph nodes examined in patients with lymph node-negative breast carcinoma.Cancer, vol. 91, no. 12, June 2001, pp. 2258–62.
Moorman PG, Hamza A, Marks JR, Olson JA. Prognostic significance of the number of lymph nodes examined in patients with lymph node-negative breast carcinoma. Cancer. 2001 Jun 15;91(12):2258–2262.
Journal cover image

Published In

Cancer

ISSN

0008-543X

Publication Date

June 15, 2001

Volume

91

Issue

12

Start / End Page

2258 / 2262

Location

United States

Related Subject Headings

  • Prognosis
  • Oncology & Carcinogenesis
  • Middle Aged
  • Lymph Nodes
  • Humans
  • Follow-Up Studies
  • Female
  • Breast Neoplasms
  • Aged, 80 and over
  • Aged