Kinetics and mechanism of axial ligand substitution of alkyl cobaloximes by substituted pyridines in different solvents

These researchers demonstrated that the trans-alkyl group in the vitamin B 12 model RCo(dmgH) 2(solvent) affects the rate and nature of the ligand exchange reaction, based on the ability of the alkyl ligand to donate electron density to the Co(III) center. The ability of the entering ligand to rapidly form a precursor encounter complex through π-π interactions affects the overall mechanism, changing from a dissociative interchange to a purely dissociative mechanism with changing π-donor capabilities of the entering ligand. © 2004 Data Trace Publishing Company.

Duke Scholars

Author Alvin L. Crumbliss Chemistry