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March 2000: A 16 year old female with a cerebellar mass.
The March COM: A 16 year old female presented with headaches and cerebellar dysfunction. MR images showed a mass lesion of the right cerebellar hemisphere with mass effect on the medulla. The mass exhibited a striated pattern of alternating isointense and hypointense zones on T1-weighted images that did not contrast enhance. The lesion was hyperintense on T2-weighted images, and also showed a striated appearance. A suboccipital craniotomy and resection of the lesion was performed. Microscopically, the specimen consisted of widened folia and a disorganized cerebellar architectonic pattern in which the internal granular cell layer was occupied by a population of large dysmorphic nerve cell bodies. Patient's diagnosed with Lhermitte-Duclos disease must be adequately evaluated for Cowden's syndrome.
Duke Scholars
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Related Subject Headings
- Nuclear Proteins
- Neurons
- Neurology & Neurosurgery
- Neurofilament Proteins
- Humans
- Headache
- Ganglioneuroma
- Gait
- Female
- Craniotomy
Citation
![Journal cover image](https://secure.syndetics.com/index.aspx?isbn=/lc.gif&issn=1015-6305&client=dukeuniv)
Published In
ISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Nuclear Proteins
- Neurons
- Neurology & Neurosurgery
- Neurofilament Proteins
- Humans
- Headache
- Ganglioneuroma
- Gait
- Female
- Craniotomy