Purification and reconstitution of the calcium release channel from skeletal muscle.
Publication
, Journal Article
Lai, FA; Erickson, HP; Rousseau, E; Liu, QY; Meissner, G
Published in: Nature
January 28, 1988
The calcium release channel from rabbit muscle sarcoplasmic reticulum (SR) has been purified and reconstituted as a functional unit in lipid bilayers. Electron microscopy reveals the four-leaf clover structure previously described for the 'feet' that span the transverse tubule (T)-SR junction. Ca2+ release from the SR induced by T-system depolarization during excitation-contraction coupling in muscle may thus be effected through a direct association of the T-system with SR Ca2+-release channels.
Duke Scholars
Published In
Nature
DOI
ISSN
0028-0836
Publication Date
January 28, 1988
Volume
331
Issue
6154
Start / End Page
315 / 319
Location
England
Related Subject Headings
- Sarcoplasmic Reticulum
- Ryanodine Receptor Calcium Release Channel
- Receptors, Cholinergic
- Rabbits
- Membrane Potentials
- Liposomes
- Ion Channels
- General Science & Technology
- Calcium
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Lai, F. A., Erickson, H. P., Rousseau, E., Liu, Q. Y., & Meissner, G. (1988). Purification and reconstitution of the calcium release channel from skeletal muscle. Nature, 331(6154), 315–319. https://doi.org/10.1038/331315a0
Lai, F. A., H. P. Erickson, E. Rousseau, Q. Y. Liu, and G. Meissner. “Purification and reconstitution of the calcium release channel from skeletal muscle.” Nature 331, no. 6154 (January 28, 1988): 315–19. https://doi.org/10.1038/331315a0.
Lai FA, Erickson HP, Rousseau E, Liu QY, Meissner G. Purification and reconstitution of the calcium release channel from skeletal muscle. Nature. 1988 Jan 28;331(6154):315–9.
Lai, F. A., et al. “Purification and reconstitution of the calcium release channel from skeletal muscle.” Nature, vol. 331, no. 6154, Jan. 1988, pp. 315–19. Pubmed, doi:10.1038/331315a0.
Lai FA, Erickson HP, Rousseau E, Liu QY, Meissner G. Purification and reconstitution of the calcium release channel from skeletal muscle. Nature. 1988 Jan 28;331(6154):315–319.
Published In
Nature
DOI
ISSN
0028-0836
Publication Date
January 28, 1988
Volume
331
Issue
6154
Start / End Page
315 / 319
Location
England
Related Subject Headings
- Sarcoplasmic Reticulum
- Ryanodine Receptor Calcium Release Channel
- Receptors, Cholinergic
- Rabbits
- Membrane Potentials
- Liposomes
- Ion Channels
- General Science & Technology
- Calcium
- Animals