TXNIP links redox circuitry to glucose control.
Publication
, Journal Article
Muoio, DM
Published in: Cell Metab
June 2007
Thioredoxin-interacting protein (TXNIP) binds and inhibits the reducing activity of thioredoxin. A new study (Parikh et al., 2007) implicates this redox rheostat as a negative regulator of peripheral glucose metabolism in humans. Investigators combined human physiology, genomic screening, and cell-based genetic studies to highlight TNXIP as a potential culprit in the pathogenesis of type 2 diabetes.
Duke Scholars
Published In
Cell Metab
DOI
EISSN
1932-7420
Publication Date
June 2007
Volume
5
Issue
6
Start / End Page
412 / 414
Location
United States
Related Subject Headings
- Thioredoxins
- Oxidation-Reduction
- Humans
- Glucose
- Endocrinology & Metabolism
- Diabetes Mellitus, Type 2
- Carrier Proteins
- 3205 Medical biochemistry and metabolomics
- 3101 Biochemistry and cell biology
- 1101 Medical Biochemistry and Metabolomics
Citation
APA
Chicago
ICMJE
MLA
NLM
Muoio, D. M. (2007). TXNIP links redox circuitry to glucose control. Cell Metab, 5(6), 412–414. https://doi.org/10.1016/j.cmet.2007.05.011
Muoio, Deborah M. “TXNIP links redox circuitry to glucose control.” Cell Metab 5, no. 6 (June 2007): 412–14. https://doi.org/10.1016/j.cmet.2007.05.011.
Muoio DM. TXNIP links redox circuitry to glucose control. Cell Metab. 2007 Jun;5(6):412–4.
Muoio, Deborah M. “TXNIP links redox circuitry to glucose control.” Cell Metab, vol. 5, no. 6, June 2007, pp. 412–14. Pubmed, doi:10.1016/j.cmet.2007.05.011.
Muoio DM. TXNIP links redox circuitry to glucose control. Cell Metab. 2007 Jun;5(6):412–414.
Published In
Cell Metab
DOI
EISSN
1932-7420
Publication Date
June 2007
Volume
5
Issue
6
Start / End Page
412 / 414
Location
United States
Related Subject Headings
- Thioredoxins
- Oxidation-Reduction
- Humans
- Glucose
- Endocrinology & Metabolism
- Diabetes Mellitus, Type 2
- Carrier Proteins
- 3205 Medical biochemistry and metabolomics
- 3101 Biochemistry and cell biology
- 1101 Medical Biochemistry and Metabolomics